Product datasheet
Anti-Substance P antibody ab67006
1 Abreviews 1 References 1 Image
Overview
Product name
Anti-Substance P antibody
Description
Rabbit polyclonal to Substance P
Tested applications
ICC/IF, IHC-Fr
Species reactivity
Reacts with: Rat
Immunogen
Synthetic peptide corresponding to Rat Substance P conjugated to Keyhole Limpet
Haemocyanin (KLH).
Positive control
Rat spinal cord dorsal horn
Properties
Form
Lyophilised:Reconstitute vial with 100 µL of distilled or deionized water.
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw
cycles.
Storage buffer
Preservative: Less than 0.09% Sodium Azide
Constituents: Whole serum
Purity
Whole antiserum
Clonality
Polyclonal
Isotype
IgG
Applications
Our Abpromise guarantee covers the use of ab67006 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
Abreviews
Notes
ICC/IF
IHC-Fr
Application notes
ICC/IF: 1/300 - 1/500.
IHC-Fr: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
1
The Substance P antiserum was quality control tested using standard immunohistochemical
methods. The antiserum demonstrates significant positive labeling of rat substantia nigra and
spinal cord using indirect immunofluorescent techniques. Specificity was demonstrated using
soluble pre-adsorption with the peptides in question at a final concentration of 10 µg of peptide
per mL of diluted antiserum. Immunolabeling was completely abolished by pre-adsorption with
Substance P. Pre-adsorption with the following peptides resulted in no reduction of
immunostaining: neurokinin A, neurokinin B, somatostatin and neuropeptide K.
Target
Function
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent
vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Sequence similarities
Belongs to the tachykinin family.
Cellular localization
Secreted.
Anti-Substance P antibody images
Detection of Substance P in rat spinal cord
dorsal horn with ab67006 (25 um sections).
Immunocytochemistry/ Immunofluorescence Substance P antibody (ab67006)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Our Abpromise to you: Quality guaranteed and expert technical support
Replacement or refund for products not performing as stated on the datasheet
Valid for 12 months from date of delivery
Response to your inquiry within 24 hours
We provide support in Chinese, English, French, German, Japanese and Spanish
Extensive multi-media technical resources to help you
We investigate all quality concerns to ensure our products perform to the highest standards
If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise,
please visit http://www.abcam.com/abpromise or contact our technical team.
Terms and conditions
2
Guarantee only valid for products bought direct from Abcam or one of our authorized distributors
3