CURRICULUM VITAE Date of last review: September 29, 2014 BIOGRAPHICAL Name: Citizenship: Business Address: Business Phone: Business Fax: E-mail address 1: E-mail address 2: Marcela Horvitz-Lennon US 4570 Fifth Avenue, Suite 600; Pittsburgh PA 15213 (412) 683.2300 x4635 (412) 683.2800 mhorvitz@rand.org Marcela.HorvitzLennon@va.org EDUCATION AND TRAINING POSTGRADUATE Sept 1992-June 1994 July 1988-June 1992 GRADUATE Sept 1993-June 1994 March 1980-Dec 1986 UNDERGRADUATE March 1980-Dec 1986 Johns Hopkins University Medical School University of Maryland Medical School Community Psychiatry Fellowship Adult Psychiatry Residency Training Johns Hopkins University (Baltimore, MD) Catholic University Medical School (Santiago, Chile) MPH (1994) Public Health MD (1987) Medicine Catholic University Medical School (Santiago, Chile) MD (1987) Medicine APPOINTMENTS AND POSITIONS July 2013 – present July 2013 – present Sept 2010 – present Sept 2010 – present Nov 2004 – Aug 2010 July 2001- Aug 2004 July 1997- Aug 2004 July 1997- Aug 2004 Oct 1994-April 1997 Veterans Health Administration, Pittsburgh PA VA Center for Health Equity Research and Promotion (CHERP), Pittsburgh PA RAND Corporation, Pittsburgh PA Dept. of Psychiatry, University of Pittsburgh Medical School Dept. of Psychiatry, University of Pittsburgh Medical School Dept. of Health Care Policy, Harvard Medical School, Boston MA Dept. of Psychiatry, Harvard Medical School, Boston MA Cambridge Health Alliance, Cambridge MA Mental Health Department, Ministry of Health (Santiago, Chile) Clinical staff Core Investigator Full Natural Scientist Adjunct Faculty Assistant Professor Lecturer Instructor Attending Psychiatrist Permanent Staff CERTIFICATION AND LICENSURE SPECIALTY CERTIFICATION American Board of Psychiatry and Neurology Re-certified 1995 June 2006 MEDICAL OR OTHER PROFESSIONAL LICENSURE Pennsylvania Board of Registration in Medicine Massachusetts Board of Registration in Medicine Maryland Board of Registration in Medicine 2004-present 1997-2005 1988-1994 MEMBERSHIPS in PROFESSIONAL and SCIENTIFIC SOCIETIES Psychiatric Services Editorial Board Member Editor Best Practices Column Co-Editor Latin American Services Research Column American Psychiatric Association Clinical Guideline Writing Group Academy Health Pennsylvania Psychiatric Society Massachusetts Psychiatric Society American Psychiatric Association Maryland Psychiatric Society 2014-present 2013-present 2010-2013 2013-present 2007-present 2004-present 1997-2004 1990-present 1990-1994 HONORS Scholars in Medicine Fellowship (Harvard Medical School) Stelios M. Stelson Fellowship (Columbus Foundation) Brody Psychotherapy Award (University of Maryland Medical School) Full Scholarship (Catholic University Medical School) 2003 1992 1992 1982, 1983, 1984 CLINICAL ACTIVITIES July 2013- present: Veterans Health Administration: Psychiatrist (Telemedicine; Integrated primary-behavioral health clinic) Nov 2004 - July 2013: Dept. of Psychiatry, University of Pittsburgh Medical School, and Western Psychiatric Institute & Clinic: Psychiatrist (Assertive Community Treatment; Emergency Department) July 1997- Aug 2004: Dept. of Psychiatry, Cambridge Health Alliance: Psychiatrist (Assertive Community Treatment) July 1998 – July 2003: Dept. of Psychiatry, Cambridge Health Alliance: Consultation/Liaison psychiatrist for primary care clinic serving a Spanish-speaking and immigrant population Sept 1994-April 1997:Private Practice, Santiago Chile Sept 1992- June 1994: Community Psychiatry Program, Johns Hopkins University Medical School: Psychiatrist (Mobile Treatment Team) July 1991-June 1993: Baltimore County Detention Center: Psychiatrist TEACHING ACTIVITIES Nov 2004 – July 2013: July 2007 – June 2008: July 2004: July 2001 – June 2003: July 2000 – June 2003: July 1997 – June 2003: Dept. of Psychiatry, University of Pittsburgh Medical School, and Western Psychiatric Institute & Clinic: Mentoring and supervision (medical students, PGYIII residents) Dept. of Psychiatry, University of Pittsburgh Medical School, and Western Psychiatric Institute & Clinic: Community psychiatry course (PGY-IV/V residents) Harvard Medical School: Mentoring, Integrated medicine-psychiatry rotation (3d year medical students) Dept. of Psychiatry, Cambridge Health Alliance and Harvard Medical School: Director and primary instructor, Basics of psychopharmacology course (PGYII residents) Harvard Medical School: Basics of medical interview course (1st year medical students). Dept. of Psychiatry, Cambridge Health Alliance and Harvard Medical School: Psychopharmacology supervision (PGYIII Residents, Prescribing Nurses) PUBLICATIONS REFEREED ARTICLES 1. Horvitz-Lennon, M., Volya, R., Garfield, R., Donohue, J., Lave, Normand, SL.T. Where you live matters: Quality and racial/ethnic disparities in the care of schizophrenia in four state Medicaid programs. Under review at Health Services Research. 2. Mulcahy, A.M., Normand, SL.T., Newcomer, J., Colaiaco, B., Donohue, J., Lave, Keeler, E., Sorbero, M., Horvitz-Lennon, M. Simulated Effects of Policies to Improve Safety of Antipsychotic Prescribing in Medicaid. Under review at Health Services Research. 3. Horvitz-Lennon, M., Volya, R., Donohue, J., Lave, J., Stein B., Normand, SL.T. (2014). Disparities in quality of care among publicly insured adults with schizophrenia in four large US states, 2002-2008. Health Services Research, 49:1121-44. doi: 10.1111/1475-6773.12162. PMID: 24628414; PMCID: PMC4111783. 4. Donohue, J., O’Malley, J.D., Horvitz-Lennon, M., Taub, A.L., Berndt, E.R., Huskamp, H.A. (2014). Changes in Physician Antipsychotic Prescribing Preferences, 2002–2007. Psychiatric Services, 65:315–322. doi: 10.1176/appi.ps.201200536. PMID: 24337224; PMCID: PMC3947600. 5. Horvitz-Lennon, M. (2013). The enduring mismatch between service need and use (column). Psychiatric Services, 64:1073-1073. PMCID: PMC24185534. 6. Huskamp, H.A., O’Malley, J.D., Horvitz-Lennon, M., Taub, A.L., Berndt, E.R., Donohue, J. (2013). How quickly do physicians adopt new drugs? The case of antipsychotics. Psychiatric Services, 64:324-330. doi: 10.1176/appi.ps.201200186. PMID: 23280376; PMCID: PMC3907700. 7. Horvitz-Lennon, M., Donohue, J., Lave, J., Alegria, M., Normand, SL.T. (2013). The effect of race/ethnicity on clozapine outcomes among Medicaid beneficiaries with schizophrenia. Psychiatric Services, 64:230-237. doi: 10.1176/appi.ps.201200041. PMID: 23242347; PMCID: PMC3713199. 8. Horvitz-Lennon, M., Iyer, N., Minoletti, A. (2013). Do low and middle income countries learn from the experience of high-income countries? Lessons from the use of atypical antipsychotics for the treatment of schizophrenia. International Journal of Mental Health, 42:33-50. doi: 10.2753/IMH0020-7411420103. 9. Horvitz-Lennon, M., Alegria, M., Normand, SL.T. (2012). The effect of race/ethnicity and geography on the adoption of innovations in the treatment of schizophrenia. Psychiatric Services, 63:1171-1177. doi: 10.1176/appi.ps.201100408. PMCID: PMC3666934. 10. Minoletti, A., Sepulveda R., Horvitz-Lennon, M. (2012). Twenty years of mental health policies in Chile: Lessons and challenges. International Journal of Mental Health, 41:21-37. doi: 10.2753/IMH0020-7411410102. 11. Watkins, K. E., Pincus, H. A., Paddock, S., Smith, B., Woodroffe, A., Farmer, C., Sorbero, M. E., Horvitz-Lennon, M. Mannle, T. Jr., Hepner, K.A., Solomon, J., and Call, C. (2011). Care for veterans with mental and substance use disorders: good performance, but room to improve on many measures. Health Affairs, 30(11): 2194-203. doi: 10.1377/hlthaff.2011.0509. PMID: 22012967. 12. Horvitz-Lennon, M., Zhou, D., Normand, SL.T, Alegria, M., Thompson, W. (2011). Racial/Ethnic service disparities among homeless adults with severe mental illnesses receiving Assertive Community Treatment. Psychiatric Services, 62:598-604. doi: 10.1176/appi.ps.62.6.598. PMID: 21632726; PMCID: PMC3648808. 13. Watkins, K.W., Horvitz-Lennon, M., Caldarone, L., Shugarman, L., Smith, B., Mannle, T., Kivlahan, D.R., and Pincus, H.A. (2011). Developing Medical Record-Based Performance Indicators to Measure the Quality of Mental Health Care. Journal for Healthcare Quality, 33, 49-67. doi: 10.1111/j.1945-1474.2010.00128.x. PMID: 21199073. 14. Mulvaney-Day, N.E., Horvitz-Lennon, M., Chen, C-n., Laderman, M., and Alegria, M. (2010). Valuing health in a racially and ethnically diverse community sample: An analysis using the valuation metrics of money and time. Quality of Life Research, 19, 1529-40. doi: 10.1007/s11136-010-9713-6. PMID: 20680690; PMCID: PMC3596787. 15. Watkins, K.W., Keyser, D.J., Smith, B., Mannle, T., Kivlahan, D.R., Paddock, S., Mattox, T., Horvitz-Lennon, M., and Pincus, H.A. (2010). Transforming mental health care in the Veterans Health Administration: A new model for measuring performance to improve access, quality, and outcomes. Journal for Healthcare Quality, 32, 33-43. doi: 10.1111/j.19451474.2010.00109.x. PMID: 20946424. 16. Caldas de Almeida, J.M., Horvitz-Lennon, M. (2010). An overview of mental health care reforms in Latin America and the Caribbean. Psychiatric Services, 61, 218-221. doi: 10.1176/appi.ps.61.3.218. 17. Horvitz-Lennon, M., Frank, R.G., Thompson, W., Baik, S.H., Alegria, M., Rosenheck, R.A., Normand, SL.T. (2009). Investigation of racial and ethnic disparities in service utilization among homeless adults with severe mental illnesses. Psychiatric Services, 60(8), 1032-1038. doi: 10.1176/appi.ps.60.8.1032. PMID: 19648189; PMCID: PMC2898183. 18. Horvitz-Lennon, M., Reynolds, S., Wolbert, R., Witheridge, T.F. (2009). The role of Assertive Community Treatment in the treatment of persons with borderline personality disorder. American Journal of Psychiatric Rehabilitation, 12, 261-277. doi: 10.1080/15487760903066446. PMID: 20514357; PMCID: PMC2877283. 19. Horvitz-Lennon, M., McGuire, T., Alegria, M., and Frank, R.G. (2009). Racial and ethnic disparities in the treatment of a Medicaid population with schizophrenia. Health Services Research, 44 (6), 2106 – 2122. doi: 10.1111/j.1475-6773.2009.01041.x. PMID: 19780855; PMCID: PMC2796317. 20. Horvitz-Lennon, M., Donohue, J., Domino, M., and Normand, SL. T. (2009). Improving quality and diffusing best practices: The case of schizophrenia. Health Affairs, 28, 701-712. doi: 10.1377/hlthaff.28.3.701. PMCID: PMC2832306. 21. Lewis-Fernandez, R., Horvitz-Lennon, M., Blanco, C., Guarnaccia, P.J., Cao, Z., Alegria, M. (2009). Significance of endorsement of psychotic symptoms by US Latinos. Journal of Nervous and Mental Disorders, 197:337-347. doi: 10.1097/NMD.0b013e3181a2087e. PMID: 19440107; PMCID: PMC2782526. 22. Stuart, E.A., Marcus, S.M., Horvitz-Lennon, M., Gibbons, R.D., Normand, SL.T. (2009). Using non-experimental data to estimate treatment effects. Psychiatric Annals, 39, 719-728. doi: 10.3928/00485713-20090625-07. PMID: 20563313; PMCID: PMC2886294. 23. Kilbourne, A.M., Horvitz-Lennon, M., Post, E.P., McCarthy, J.F., Cruz, M., Welsh, D., Blow, F. (2007). Oral health in veterans diagnosed with serious mental illness. Journal of Public Health Dentistry, 67, 42-48. PMID: 17436978. 24. Horvitz-Lennon, M., Kilbourne, A.K, Pincus, H.A. (2006). From silos to bridges: Meeting the general health care needs of severely mentally ill adults. Health Affairs, 25,659-669. doi: 10.1377/hlthaff.25.3.659. PMID: 16684729. 25. Timbie, J., Frank, R.G., Horvitz-Lennon, M., Normand, SL.T. (2006). A meta-analysis of the effect of evidence-based care for depression on labor supply. Psychiatric Services, 57, 212-218. doi: 10.1176/appi.ps.57.2.212. PMID: 16452698. 26. Horvitz-Lennon, M., O’Malley, J., Frank, R.G., Normand, SL.T. (2005). Improving traditional intention-to-treat analyses: A new approach. Psychological Medicine, 35, 961-970. PMID: 16045063. 27. Tchernis, R., Horvitz-Lennon, M., Normand, SL.T. (2005). On the use of discrete choice models for causal inference. Statistics in Medicine, 24, 2197-2212. doi: 10.1002/sim.2095. PMID: 15887310. 28. Horvitz-Lennon, M., Normand, SL.T., Frank, R.G., Goldman, H.H. (2003). Usual care for major depression in the 1990’s: Characteristics and expert-estimated outcomes. American Journal of Psychiatry, 160, 720-726. PMID: 12668361. 29. Horvitz-Lennon, M., Normand, SL.T., Gaccione, P., Frank, R.G. (2001). Partial versus full hospitalization for adults in psychiatric distress: A systematic review of the published literature (1957-1997). American Journal of Psychiatry, 158, 676-685. doi: 10.1176/appi.ajp.158.5.676. 30. Weiden, P., Rapkin, B., Mott, T., Zygmunt, A., Goldman, D., Horvitz-Lennon, M., Frances, M. (1994). Rating of Medication Influences (ROMI) Scale in schizophrenia. Schizophrenia Bulletin, 20, 297-310. PMID: 7916162. 31. Levav, I., Lima, B., Horvitz-Lennon, M., Kramer, M., Gonzalez, R. (1989). Mental health for all in Latin America and the Caribbean? The epidemiological bases for action. Boletin de la Oficina Sanitaria Panamericana (OPS/PAHO), 107, 196-219. OTHER PUBLICATIONS 1. Scharf, D.M., N.K. Eberhart, N.S. Hackbarth, M. Horvitz-Lennon, R.L. Beckman, B. Han, S.L. Lovejoy, H.A. Pincus, and M.A. Burnam. (2014). Improving the Physical Health of Adults with Serious Mental Illness. Santa Monica, CA: RAND. 2. Scharf, D.M., N.K. Eberhart, N.S. Hackbarth, M. Horvitz-Lennon, R.L. Beckman, B. Han, S.L. Lovejoy, H.A. Pincus, and M.A. Burnam. 2014. Evaluation of the SAMHSA Primary and Behavioral Health Care Integration (PBHCI) Grant Program: Final Report (Task 13). Santa Monica, CA: RAND. 3. Horvitz-Lennon, M. (2014), Reply (Cohen, D: Prescribers fear as a major side-effect of clozapine). Acta Psychiatrica Scandinavica, 130: 156. doi: 10.1111/acps.12291. PMID: 24870215. 4. Wooding, S., A. Pollitt, S. Castle-Clarke, G. Cochrane, S. Diepeveen, S. Guthrie, M. HorvitzLennon, V. Larivière, M.M. Jones, S. Ni Chonaill, C. O'Brien, S.S. Olmsted, D.J. Schultz, E. Winpenny, H.A. Pincus, and J. Grant. 2013. Mental Health Retrosight: Understanding the Returns from Research (Lessons from Schizophrenia): Policy Report. Santa Monica, CA: RAND. 5. Wooding, S., A. Pollitt, S. Castle-Clarke, G. Cochrane, S. Diepeveen, S. Guthrie, M. HorvitzLennon, V. Larivière, M.M. Jones, S. Ni Chonaill, C. O'Brien, S.S. Olmsted, D.J. Schultz, E. Winpenny, H.A. Pincus, and J. Grant. 2013. Mental Health Retrosight : Identifying the Attributes of Successfully Translated Research (Lessons from Schizophrenia). Santa Monica, CA: RAND. 6. Pollitt, A., S. Diepeveen, S. Guthrie, M. Horvitz-Lennon, M.M. Jones, S. Ni Chonaill, D.J. Schultz, H.A. Pincus, J. Grant, and S. Wooding. 2013. Mental Health Retrosight : Perspectives. Santa Monica, CA: RAND. 7. Minoletti, A., Rojas, G., Horvitz-Lennon, M. Integrating Mental Health into Primary Care: Lessons from the Experience of Chile. In: Sorel E., ed. 21st Century Global Mental Health. Burlington, MA: Jones & Bartlett Publishers; 2013. 8. Goldman, H.H., Horvitz-Lennon, M., Hu, T-W., Alegria, M., Chisholm, D.H., Heinze, G., Njenga, F.G., Regier, D.A., Sayce, L. The Economic Consequences of Revising the Diagnostic Nomenclature for Mental Disorders. In: Saxena, Shekhar, Patricia Esparza, Darrel A. Regier, and Benedetto Saraceno, eds. Public Health Aspects of Diagnosis and Classification of Mental and Behavioral Disorders: Refining the Research Agenda for DSM-5 and ICD-11. American Psychiatric Pub, 2012. 9. Horvitz-Lennon, Marcela, Katherine E. Watkins, Harold Alan Pincus, Lisa R. Shugarman, Brad Smith, Teryn Mattox and Thomas E. Mannle. Veteran's Health Administration Mental Health Program Evaluation Technical Manual. Santa Monica, CA: RAND Corporation, 2009. http://www.rand.org/pubs/working_papers/WR682.html. SEMINARS, TALKS, POSTERS Poster: “Disparities in Quality of Care among Medicaid Beneficiaries with Schizophrenia in a Large State, 2002-2008,” presented at the Annual Meeting of Academy Health (Baltimore, June 23 2013). Talk (Invited Session): “The Effect of Race/Ethnicity and Geography on Adoption of a Novel Antipsychotic Medication among Publicly Insured Adults with Schizophrenia,” Annual Conference: Mental Health Service Disparities, From Disparities Research to Disparities Interventions: Lessons Learned and Opportunities for the Future of Behavioral Health Services (Arlington VA, April 6 2011). Talk (Invited Session): “Racial and Ethnic Disparities in the Treatment of a Medicaid Population with Schizophrenia,” National Hispanic Science Network 2010 International Conference (New Orleans, September 30, 2010). Grand Rounds: "Are there Racial and Ethnic Disparities in Service Utilization Among People who are Severely Mentally Ill and Homeless?," Columbia Center for Homelessness Prevention Studies (http://cchps.columbia.edu), Columbia University Medical School (New York, April 17 2008). Talk (Invited Session): “An Investigation of Racial/Ethnic Disparities in Service Utilization among Severely Mentally Ill Homeless Adults,” Annual Meeting of the American Public Health Association (Washington DC, November 7 2007). Poster: “An Investigation of Racial/Ethnic Disparities in Service Utilization among Severely Mentally Ill Homeless Adults,” presented at the Annual Meeting of Academy Health (Florida, June 4 2007). Talk (Invited Session): “A Naturalistic Study of Serious Adverse Effects of Atypical Antipsychotics in a Large Multi-ethnic Publicly Insured US Population,” Spring Meeting of the International Biometric Society, Eastern North American Region [ENAR] (Pittsburgh, March 2004). Poster: “A Naturalistic Study of Serious Adverse Effects of Atypical Antipsychotics in a Large Multi-ethnic Publicly Insured US Population,” presented at the American Psychiatric Association’s Institute on Psychiatric Services, 55th Annual Meeting (Boston, October 2003). Symposium (guest speaker): “Psychiatric partial hospitalization in a public mental health system,” Mental Health Unit, Ministry of Health (Santiago, August 2002). Talk: “Methodological Challenges of Broken Controlled Trials for Psychiatric Outcome Research,” 15th NIMH-sponsored International Conference on Mental Health Services Research (Washington D.C., April 2002). Forum (speaker and moderator): “Meeting Mental Health Information Needs for the Public Health System,” Mental Health Unit, Ministry of Health (Santiago, August 1998). Seminar: “Where Hispanics are a Minority within Minorities,” presented at a Symposium on Hispanics’ Service Needs, chaired by Renato Alarcon MD MPH. American Psychiatric Association’s Institute of Hospital and Community Psychiatry (Baltimore, October 1993). Poster: “Medication Compliance among the Homeless Mentally Ill,” presented at the Young Investigators Session, 145th annual meeting of the APA (Washington D.C., May 1992). Conference: Co-chairperson, Scientific Program of the IV International Symposium of the American Association of Hispanic Psychiatrists, Puerto Vallarta, Mexico, March 1992. Seminar: “Training in the US: applicable to Latin-America?,” presented at the Symposium “NorthLatin American Psychiatry: Opposing Issues,” chaired by Bruno Lima MD MPH. 144th annual meeting of the American Psychiatric Association, New Orleans, May 1991. OTHER Journal Refereeing: Health Services Research; Medical Care; Psychiatric Services; American Journal of Public Health; British Journal of Psychiatry; Journal of Clinical Psychiatry; Administration and Policy in Mental Health and Mental Health Services Research; Internet Journal of Mental Health Ad Hoc Grant reviews for NIH (2013) RESEARCH RESEARCH INTERESTS Quality and value of care for persons with mental illnesses Health care disparities (racial/ethnic, geographic) Public payer antipsychotic drug policies Physician prescribing behavior Underuse of high-value practices and overuse of low-value practices Care of medical comorbidities Services and policies in low- and middle-income countries (LMICs) Diffusion of innovations GRANTS & CONTRACTS ACTIVE 1R01MH093359 - 01A1 (Huskamp, Donohue) 4/1/12 – 3/31/15 NIMH Influences on Psychiatrist Prescribing of Antipsychotics The goals of this project are to examine the adoption of new antipsychotic medications by psychiatrists and how psychiatrists respond to new information about medication safety and efficacy from different sources. Role: Co-Investigator R01 (Breslau, Yu) 4-year grant NIMH Integrating Physical and Mental Care for Adults with Serious Mental Illness The proposed research will leverage a natural experiment to test various approaches to integrated care in New York State in order to study economic and client outcomes of the integration of physical and behavioral health care for individuals with severe mental illness. Role: Co-Investigator PENDING R01 (Horvitz-Lennon, Normand) 4-year grant NIMH Improving Value of Publicly Funded Mental Health Care The goal of the proposed research is to investigate antipsychotic utilization and its impacts among Medicaid, Medicare, and dually eligible beneficiaries, and using these findings, to simulate the impacts of strategies to improve value of care. Role: Principal Investigator R21 (Horvitz-Lennon, Minoletti) NIH-Fogarty International Center An Integrated Care Model for People with Severe Mental Illnesses in Chile 2-year grant The goal of the proposed research is to develop and later test an intervention to advance access, quality, and efficiency of care for people with SMI living in LMICs, and to build capacity to successfully implement and evaluate the developed integrated care intervention. Role: Principal Investigator COMPLETED 1 R01 MH087488-01A1 (Horvitz-Lennon, Normand) 9/15/2010 - 7/31/2014 NIMH An In-Depth Investigation of Racial & Ethnic Disparities in Schizophrenia Care The major goal of this proposal is to assess disparities in quality of care and to systematically estimate the contribution of county-level factors to disparities. Role: Principal Investigator HHSP23320095649WC (Burnam) 10/1/2010 – 9/30/2013 DHHS Evaluation of the SAMHSA Primary and Behavioral Health Care Integration (PBHCI) Grant Program The goal of this project is to conduct an independent and objective national evaluation of the PBHCI program. Role: Co-Investigator 11043 (Wooding/Pincus/Horvitz-Lennon) 10/1/10-5/13 The Graham Boeckh Foundation Science of Science for Mental Health Research Network Mental Health Retrosight – Phase 2 The goal of this project is to investigate the translation and payback from schizophrenia-relevant research into actual schizophrenia care. Role: Co-Investigator REFERENCES Upon Request