summer 2008 B ringing better health to your horses FINE TUNER of Fusion EHRF Fellow Dr. Luca Panizzi WESTERN COLLEGE OF VETERINARY MEDICINE • EQUINE HEALTH RESEARCH FUND E H R F C ove r s the West I N S I D E 4 Akin to the Fund Nearly three decades after Dr. Jeremy Bailey was an EHRF Fellow, the large animal surgeon, professor and associate dean (academic) is retiring. 6 Diggin’ Deep Five WCVM-based research teams dig deep to investigate five horse health research studies with the support of the Equine Health Research Fund. 8 Carpal Spavin Surgery, Fine Tuned EHRF Research Fellow Dr. Luca Panizzi teamed up with equine surgeon Dr. Spencer Barber to test a less invasive technique for treating carpal spavin. 10 Study Sheds New Light on Night Blindness A WCVM study’s results show a definite association between congenital stationary night blindness and coat patterns in the Appaloosa breed. 11 Straight from the Horse’s Mouth Veterinary dentist Dr. James Anthony talks about the growing recognition of dentistry’s importance in equine health — and a glimpse of its future. 14 Key Facts about Equine Herpes Virus Learn more about equine herpes virus and how you can prevent its spread among horse populations. FRONT COVER: EHRF Research Fellow Dr. Luca Panizzi with one of his research horses in WCVM’s paddock area. Panizzi has been investigating a less invasive arthrodesis technique for treating carpal spavin in horses. H O R S E H E A L T H L I N E S Horse Health Lines is produced by the Western College of Veterinary Medicine’s Equine Health Research Fund. Visit www.ehrf.usask.ca for more information. Please send comments to: Dr. Hugh Townsend, Editor, Horse Health Lines WCVM, University of Saskatchewan 52 Campus Drive, Saskatoon, SK S7N 5B4 Tel: 306-966-7453 • Fax: 306-966-7274 wcvm.research@usask.ca For article reprint information, please contact sm.ridley@sasktel.net. When Western Canada’s cold weather puts most riding and driving events on ice, horse people do the next best thing: take in the region’s annual equine trade shows, conferences and meetings. In the past months, representatives from WCVM have promoted the Equine Health Research Fund and the College’s matching gift incentive program at several of these equine events. To raise more awareness about WCVM’s “Give $1, Invest $2 in Horse Health” campaign, the Fund also organized several draws for embroidered rain sheets and coolers. Combined with matching funding, proceeds from these draws have raised more than $1,400 for equine health research activities at WCVM. • The Mane Event Equine Education and Trade Fair, Chilliwack, B.C. (top photo, left to right): Two EHRF Fellows — Drs. Luca Panizzi and Tal Raz — joined WCVM development officer Patti Tweed and second-year veterinary student Hayley Lang at this mega-trade show from October 19-21, 2007. WCVM representatives also met with horse owners in the demonstration ring where they gave tips on basic equine veterinary care. Throughout the weekend, EHRF advisory board members Drs. John Twidale and David Paton joined the WCVM team along with Drs. Theresa Burns, Kirsten Schwichtenberg, Farshad Maloufi, Hermen Geertsema and Eric Martin. The raffle winner was Kelly Bilquist, a horse owner from Gabriola Island, B.C. • Alberta Horse Breeders and Owners Conference, Red Deer, Alta.: Veterinary students Carolyn Kondra, Nicole MacMillan, Jamie Rothenburger and Jenna Bayne travelled with EHRF Fellow Dr. Chris Bell to attend this popular conference from Jan. 11-13. Dr. Katharina Lohmann of WCVM also gave a presentation on geriatric horse care during the weekend. In the second photo (left to right), MacMillan and Kondra present an embroidered rain sheet to raffle winner Laurie Thiessen of St. Albert, Alta. • WCVM Equine Club’s annual Equine Seminar, Saskatoon, Sask.: On February 2, nearly 300 people — Pony Club and 4-H members and their chaperones and parents — came to WCVM to learn more about equine health care from more than two dozen WCVM Equine Club members. The students organized 15 different presentations with topics ranging from dentistry and first aid to performance-related injuries. Veterinary student Tamara Quaschnick (bottom photo, left) presents an embroidered cooler to the day’s winner, Brandy Dobroskay from Dalmeny, Sask. • Saskatchewan Horse Federation annual general meeting, Regina, Sask.: Field service resident Dr. Kristin Poirier and veterinary student Carolyn Kondra represented the EHRF at the weekend conference that took place from March 7-9. Marie Fitzgerald of Saskatoon, Sask., was the raffle winner. • Royal Manitoba Winter Fair, Brandon, Man.: Members of the Manitoba Equine Ranching Association and the North American Equine Ranching Information Council (NAERIC) promoted the Fund by distributing copies of Horse Health Lines and other EHRF material at the organization’s booth during the week-long fair that began on March 29 and wrapped up on April 5. H M a k e Yo u r Match! Western Canadian horse owners helped the Western College of Veterinary Medicine meet the $100,000 maximum for the matching gift incentive program’s first year. Now let’s make it two years in a row! Through a five-year fund raising incentive, the Heather Ryan and L. David Dubé Foundation has pledged to match any “new” funding dollars to the College’s equine health research programs. In total, the Foundation will contribute as much as $500,000 in matching funds over five years — beginning in 2006 and ending in 2011. The goal is that this unique incentive will encourage more horse owners, horse sport groups, breed associations and equine businesses to support vital equine health research at WCVM. And remember, any amount that you or your organization can give will make a significant impact on horse health — especially when it can be doubled! Here’s how you can double your investment in equine health research: • BECOME a donor. As a first-time contributor to the Equine Health Research Fund, your gift will increase the Fund’s annual donations used to conduct cutting-edge research, to train equine specialists and to generate valuable horse health information. • BOOST your annual donation. Every dollar that you give to the Equine Health Research Fund over and above the amount of your usual contribution will be matched. • INVEST in major equine health research projects at WCVM. Besides its support of the EHRF, the Heather Ryan and L. David Dubé Foundation is investing in large-scale, collaborative research initiatives at WCVM over the next five years. The Foundation will donate one dollar for every dollar that you contribute to supporting these high-priority projects that focus on critical issues in horse health. For more details, contact WCVM’s Development Office at 306-966-7450 (wcvm.supportus@usask.ca). Western College of Veterinar y Medicine 3 Dr. Jeremy Bailey Akin to the Fund There are some people at the Western College of Veterinary Medicine who share a special kinship with the Equine Health Research Fund — people whose careers are intertwined with the organization’s growth, whose names are associated with key events in the Fund’s three-decade history. Dr. Jeremy Bailey is one of those individuals. Long before he put his own brand on the role of WCVM’s associate dean (academic) and years before he established his reputation as a veterinary surgeon, researcher and teacher, Bailey was the third graduate student to take on the title of EHRF Research Fellow. 4 Horse Health Lines • Summer 2008 The year was 1979. When Bailey walked into the Large Animal Clinic on the first morning of his residency, the Fund’s first Fellow — Dr. Hugh Townsend — had just joined the veterinary college’s faculty after completing his residency. The second EHRF Fellow, Dr. Neil McKenzie, was halfway through his two-year program. Before arriving at WCVM, Bailey’s career had already taken him a long way from home. Born and raised in Zimbabwe, the young clinician had earned his Doctor of Veterinary Medicine degree from the University of Pretoria (Onderstepoort) in 1973. After practising in South Africa and England for several years, he moved to Alberta where he worked in mixed animal practices based in Stettler and Edmonton. Bailey first heard about the new EHRF fellowship when he attended a meeting of the Western Canadian Association of Equine Practitioners at WCVM. Closely involved with horses since his youth in Zimbabwe, Bailey was keen on the chance to specialize in equine clinical studies. He came to WCVM just as a golden era for equine health research and training was ramping up at the veterinary college. For an equine resident who was eager to gain clinical and surgical experience, WCVM’s Veterinary Teaching Hospital offered the ideal caseload with performance horses and racehorses coming from Winnipeg, Edmonton, Calgary and even Vancouver for treatment. “Those were the days when intra-articular surgery was in its development stages,” explains Bailey. “Many of the cases involved bone chips, but we were treating those with open arthrotomies as opposed to arthroscopies. The surgeons started using arthroscopy a few years later while Dr. Mark Hurtig (EHRF Fellow from 1982-84) was here.” While Bailey gained valuable experience in WCVM’s surgery suites, he was also working on a research project as part of his Master of Veterinary Science program. The EHRF Fellow collaborated with his graduate supervisor, Dr. Frank Bristol, a reproduction specialist who was gaining international recognition for his foundational work in the behaviour of pasture breeding stallions. Bailey’s research study focused on uterine involution in mares after induced parturition, and the researchers’ findings were eventually published in the American Journal of Veterinary Research in 1983. Bailey joined WCVM’s faculty as a large animal surgeon as soon as he finished his residency in 1981, but the change in roles didn’t diminish his involvement with the Fund. Back then, anyone who was interested in equine work was part of the EHRF management committee, and faculty members and residents all took turns participating in the Fund’s “travelling road show” — a series of equine health presentations that were given across Western Canada for horse owners and enthusiasts. “I think for the College, it was an important effort since many western Canadians did not fully understand or appreciate the kinds of facilities and resources that we had here at WCVM,” says Bailey, looking back at the EHRF public presentations. “It was an exciting time — the whole equine program was really growing.” As the Fund’s research and training programs grew, so did Bailey’s equine research interests with An equine treadmill demonstration during the 2007 Vetavision. much of his work reflecting the same issues that he and other WCVM surgeons dealt with on a daily basis: “We used to see some fairly severe lacerations in horses, so “I think it was an accomplishment to get everybody here had some level of interest in wounds and basic wound healing techniques.” that level of technology to the College: But if the veterinary surgeon had to choose his favourite area of interest, it was soft tissue surgery: wound healing, at the time, our treadmill was the only abdominal surgery and upper airway problems in horses, to be specific. That clinical and research interest led to an even larger one of its kind in Western Canada.” venture when Bailey took on a leading role in bringing a highspeed treadmill to the veterinary college and establishing the Equine Performance Centre. It wasn’t an easy task: Bailey and his colleagues initially had to raise These kinds of research achievements provided Bailey with ideal material $270,000 to pay for the treadmill and an in-ground force plate as well as for for another EHRF-related role that he filled. He was the longtime editor of the refurbishment and expansion of an old animal isolation building at the Horse Health Lines — a volunteer job that he looks back at with affection. veterinary college. Eventually, enough funding came from several different “It was good fun,” says Bailey, who edited and outlined Horse Health sources including a grant from the Natural Sciences and Engineering Lines’ layout twice a year whenever he could spare the time from his clinical, Research Council of Canada (NSERC) and support from WCVM, U of S, and teaching and research duties. the Western Canadian Veterinary Students’ Association. Altogether, the veterinary surgeon was editor of 12 of the publication’s During the centre’s official opening in April 1997, students worked with issues from April 1992 to April 1998. But after becoming WCVM’s associate a Percheron-cross grey mare named Pat to demonstrate the treadmill to a dean (academic) in July 1997, Bailey finally decided to turn over his editor’s crowd of people that included U of S President George Ivany — one of the role to Dr. Hugh Townsend. centre’s individual supporters. The demands of Bailey’s role in the Dean’s Office have limited his “It was where things were going at the time: people were starting to use involvement in the EHRF’s recent activities and programs, but even as he high-speed treadmills to assess upper airway problems. I think it was an prepares to retire from the College in December 2008, Bailey’s interest in the accomplishment to get that level of technology to the College: at the time, it Fund’s growth and its future still remains strong. For when you really think was the only one of its kind in Western Canada,” says Bailey, one of several about it, Bailey’s successful association with WCVM over the past 30 years may clinicians who have used the centre’s technologies for research related to never have happened if it wasn’t for the Fund. respiratory diseases, locomotion and lameness issues. “Would I have come to the College without the EHRF fellowship? In the late 1990s, the treadmill also played a specific role in a Probably not, because there wouldn’t have been any other choice (for groundbreaking, EHRF-supported study that defined the function of the advanced training) in horses,” admits Bailey. equine guttural pouch. A WCVM-based research team that included Drs. Keith In other words, it’s just one more example of how the Equine Health Baptiste, Jonathan Naylor and Bailey made the discovery, and their work Research Fund has brought good things — and good people — to the was eventually published in Nature — one of the most prestigious science Western College of Veterinary Medicine. H magazines in the world. Western College of Veterinar y Medicine 5 Diggin’ DEEP You don’t win at barrel racing without digging deep around those critical corners — and the same can be said for achieving success in the arena of equine health research. This year, five teams at the Western College of Veterinary Medicine are rising to the challenge and taking an in-depth look at health issues that affect horses around the world. WCVM’s Equine Health Research Fund is supporting the scientists’ studies with nearly $70,000 — essential research funding that comes directly from members of Western Canada’s horse industry. What’s the shelf life of pergolide mesylate? Drs. Trish Dowling and Katherine Ball, WCVM; and Dr. Gordon McKay, U of S College of Pharmacy and Nutrition Pituitary pars intermedia dysfunction (PPID) — or equine Cushing’s disease — is a significant health problem in senior horses, affecting one in 10 horses more than 20 years of age. Affected horses commonly suffer careerlimiting and potentially fatal complications such as laminitis and chronic infections. In many cases, PPID can be successfully managed with the dopamine agonist pergolide that’s normally administered orally as the mesylate salt. There’s no approved veterinary formulation of pergolide in North America, and since the approved human formulations have been withdrawn from the market, veterinarians must rely on pergolide mesylate formulated from active pharmaceutical ingredients. However, the stability of pergolide mesylate in these formulations is currently unknown. This places treated horses at risk of treatment failure and devastating complications from sub-therapeutic doses. In this study, the research team will measure the concentration of pergolide mesylate in oral solutions on eight different occasions during a 20-week period. The researchers will analyze three separate batches from three different pharmacies to determine the rate of pergolide degradation, 6 Horse Health Lines • Summer 2008 then compare results between pharmacies to determine if the different formulations behave similarly. By determining the stability of pergolide mesylate in compounded oral solutions, the research team will be able to recommend appropriate shelf lives and improve the use of pergolide in treating horses with PPID. What’s the most effective protocol for diagnosing R. equi pneumonia in foals? Drs. Fernando Marqués, Steve Manning, Kristin Poirier, Katharina Lohmann, Andy Allen, John Pharr, Marianela López and Hugh Townsend Rhodococcus equi is the most devastating cause of pneumonia in young foals and is of great economic significance in many parts of the world. The disease is characterized by chronic, progressive and often fatal pneumonia in foals between three weeks and five months of age. Pneumonic lesions develop slowly and clinical signs usually remain undetected until the disease is well advanced, a feature that increases the cost and limits the efficacy of treatment. In this study, the research team will use an R. equi disease model that closely mimics natural disease. By following the foals from the time of infection, researchers will be able to determine the time at which disease becomes detectable — providing new information on the early detection, timing and development of lung lesions. This project’s goal is to develop a sensitive and specific protocol for the diagnosis of R. equi pneumonia in foals as an aid to clinical veterinarians involved in the diagnosis, treatment and prevention of this disease. As well, the research team will provide clinical researchers with a reliable diagnostic outcome that can be used in experimental studies. What plate technique is the strongest for pastern arthrodesis? Drs. James Carmalt, David Wilson and Chris Bell Horses that develop debilitating arthritis of the pastern joint are frequently middle-aged, highly-trained athletes and their inability to perform results in significant economic and emotional loss to their owners. The disease known as high ring bone is a common condition, especially in western performance horses, and was often career ending until surgical techniques to fuse the joint (arthrodesis) were developed. Equine surgeons use one of two recommended techniques for fusing the pastern joint: one involves placing parallel screws across the joint while the second, more-preferred method consists of using a bone plate called the limited contact-dynamic compression plate (LC-DCP) combined with parallel screws. So far, no research team has compared the cyclic fatigue properties of this technique with the parallel screw method or with the new generation of bone plate — the locking contact plate (LCP). LAMINITIS STUDY RECEIVES GRANT: This spring, the Heather Ryan and L. David Dubé Veterinary Health and Research Award allocated $128,000 to a twoyear WCVM investigation of laminitis — a severe health issue that affects horses around the world. Led by Dr. Baljit Singh of WCVM’s Veterinary Biomedical Sciences, the research team will evaluate the expression and function of Toll-like receptor (TLR) 4 and 2 in lamellar tissues from normal and inflamed equine hooves. TLR4 and TLR2 are innate immune molecules that activate cell signalling in response to bacterial products such as endotoxins. This activation of cells leads to the expression of inflammatory cytokines, the migration of activated neutrophils and tissue damage. Based on previous research, Singh and his collaborators believe TLR4 and TLR2 play a central role in the development of laminitis. By inhibiting cell activation induced by TLR4 and TLR2, the team expects to be able to inhibit the development of laminitis in two models of this disease. Singh, whose research focuses on the mechanisms of inflammation, will collaborate on this study with three people: Dr. Sarabjeet Suri, a molecular biologist; Dr. Hugh Townsend, a specialist in vaccine efficacy and infectious diseases; and Dr. David Wilson who has more than 20 years of experience in equine orthopedics. Visit www.ehrf.usask.ca for further updates on WCVM’s horse health research projects. In this project, the research team will use the limbs of equine cadavers to biomechanically compare the cyclic fatigue properties of the LC-DCP augmented by 5.5 millimetre transarticular screws and the new LCP plate combined with transarticular screws. Based on the study’s results, the team will determine which of the plate-augmented techniques provides equine patients with the strongest implant after surgery. What are the characteristics of immune regulators in fertile and subfertile mares? Drs. Claire Card and Sarah Eaton Persistent post-mating uterine inflammation is the main cause of subfertility in mares. Subfertile mares usually have increased bacterial contamination of the genital tract with fecal and genital bacteria because of poor vulvar conformation and wind sucking. Genital tract contamination increases the probability of bacteria ascending, colonizing the uterus and contributing to endometritis. So far, no one completely understands how bacteria and sperm interact with the immune system in subfertile and fertile mares. In this study, Dr. Claire Card and theriogenology resident Dr. Sarah Eaton will evaluate the immune mechanisms responsible for uterine inflammation in terms of certain key immune regulators: Toll-like receptors, neutrophils and cytokines. The scientists will also evaluate fertile and subfertile mares and analyze the effect of endometrial biopsy features, stage of cycle, season and breeding on these immune regulators. Findings from this study will help clinicians understand the pathogenesis of excess uterine inflammation in mares that are subfertile and determine the tissue and cytologic features of mares with endometritis due to breeding. Eventually, the information will help to determine whether treatments that decrease cytokine production are an effective strategy to decrease uterine inflammation in subfertile mares. What does a horse’s nasomaxillary opening look like? Drs. James Carmalt and Chris Bell A horse’s paranasal sinus system consists of six pairs of sinuses with a common drainage path (the nasomaxillary opening) to the nasal cavity. This path hasn’t been clearly defined in the horse, and no one has a definite understanding of whether there’s a single opening, two closely related openings from each of the rostral and caudal maxillary sinuses, or two distinct drainage pathways. For veterinary surgeons, gaining a better understanding of the nasomaxillary opening’s anatomy would be helpful since the pathway is vital to the normal clearance of the sinus system in health and disease. Conditions of the paranasal sinuses such as sinusitis, paranasal sinus cysts, neoplasia and ethmoid hematoma have a direct impact on the function and anatomy of the nasomaxillary opening. During this study, Dr. James Carmalt and large animal surgery resident Dr. Chris Bell will describe the clinical and three-dimensional anatomy of the nasomaxillary opening in the horse using axial computed tomography (CT) and gross anatomy on equine cadavers. As a result, the researchers will be able to accurately describe the horse’s nasomaxillary opening and its relations to paranasal sinus pathology. H Western College of Veterinar y Medicine 7 Several years ago, Dr. Spencer Barber at the Western College of Veterinary Medicine (WCVM) achieved a first in equine surgery when he developed a successful arthrodesis (surgical fusion) technique for treating a debilitating arthritic condition in horses called carpal spavin. This degenerative disease affects the carpometacarpal joint — the lower joint space of the knee in a horse’s front leg. Carpal spavin is most commonly diagnosed in middle-aged to older horses — especially in the Arabian and Quarter horse breeds. Unfortunately, the pain associated with carpal spavin can’t be controlled with normal intra-articular medication used for other arthritic conditions in horses. As a result, affected horses usually become so severely lame that most patients are humanely euthanized within two to three years after diagnosis. Barber’s surgical procedure offered horse owners a much more attractive option. By inserting a drill bit into a horse’s carpometacarpal joint in several places, Barber used a “fanning” motion to destroy cartilage and bone, helping the joint fuse together during the horse’s recovery. Once the joint fused, his patients were able to walk normally without any pain. While the procedure seemed to work well, it was very invasive and required four or five different entry points. The technique was also subjective, and it was challenging for other surgeons to successfully repeat the procedure in their patients. As an alternative, Barber devised a new, less invasive technique using two entry points and three drill tracts into the joint. The concept is based on a similar arthrodesis procedure developed for the equine tarsus (or hock) — another “low motion” joint. Carpal Spavin Surgery, Here’s the drill And that’s where Dr. Luca Panizzi enters the story. Not long after the large animal surgical resident arrived at WCVM in 2006, Barber asked him if he wanted to test the minimallyinvasive technique in a research study as part of his Master of Veterinary Science (MVetSc) program. “I’m interested in orthopedics so I thought, ‘Why not?’” says Panizzi, now in the third and final year of his residency and graduate degree. “If this technique proves to be as good as the one that Dr. Barber first developed, it will mean that we can use a less invasive approach and get the same result: a sound horse that’s still usable.” Panizzi, Barber and summer research student Hayley Lang began the research trial during the spring of 2007. After initially testing and perfecting the modified arthrodesis technique on the limbs of equine cadavers, Panizzi performed the surgery in six healthy horses that were selected for the research project. One carpometacarpal joint of each horse underwent the treatment. Through a single point of entry, Panizzi directed the drill bit in three different directions to destroy some of the cartilage and subchondral bone in the joint. “We’re trying to cause a counterbalance between not causing too much damage to the cartilage and bone — but enough to cause the joint to fuse,” explains the resident. 8 Horse Health Lines • Summer 2008 FINE TUNED By David Shield Unlike Barber’s initial technique, this method is standardized with particular measurements and angles for the drill bit passes. During the procedures, Panizzi also used the veterinary college’s C-arm fluoroscope unit to guide and measure his movements. Fast-tracked fusion All of the horses received anti-inflammatory drugs for the first few days after their surgeries, and as expected, the animals were still noticeably lame two to three months later. “After that point, they became progressively better,” says Panizzi. He adds that it usually takes about six to eight months for the joint to completely fuse. The research team took radiographs of the horses’ treated carpometacarpal joints one day after surgery, and then took further X-rays at four, six, eight and 12 months post-surgery. Panizzi and Barber also used the veterinary college’s force plate to determine each horse’s grade of lameness: those evaluations took place before surgery and at six, eight and 12 months post-surgery. By the eight-month mark, Panizzi says four of the six horses appeared to be sound without any lingering issues from the surgical procedure. Additional analyses must be completed in the next few months before CMC the research team can make any concise conclusions about the new technique. However, after watching the horses’ progress in the past year, Panizzi believes the new procedure should help horses heal faster than the previous technique. “Being minimally invasive means creating less pain and less damage, and hopefully the joint will fuse in a shorter amount of time with minimal pain.” Since the lower carpal joint doesn’t move very much, Panizzi says surgical fusion shouldn’t affect the locomotion of the horse: treated horses should be able to walk, trot and even gallop. “When you flex the knee in a horse, that joint doesn’t open up. It’s just a very minimal motion, but apparently it’s enough to create pain when the cartilage is damaged,” he says. Apart from the study, Panizzi says the research team used the new arthrodesis procedure on two clinical patients that were diagnosed with carpal spavin at WCVM’s Veterinary Teaching Hospital last summer. “We performed surgery on one case around the same time as the research project’s surgeries. Since then, the owner was in touch with us and she said the horse is doing fine,” points out Panizzi. Will the new arthrodesis procedure prove to be the best alternative for treating patients diagnosed with carpal spavin? Panizzi says that can only be determined after it’s used in more clinical cases and develops a track record. But ultimately, results from this research project will help to fine tune the fusion process: “The idea is that if this arthrodesis technique works in normal horses, there’s a good chance that’s it’s going to work in horses that have the disease.” H David Shield has written for many Saskatchewan-based publications including Planet S Magazine, U of S On Campus News, Pulsepoint Magazine and Eagle Feather News. He also works as a casual reporter for CBC Radio News in Saskatoon, Sask. CARPAL CLOSE UP: The photo (far left) shows a horse’s leg after surgical fusion of its carpometacarpal joint. The noticeable bump (see arrow) is caused by new bone that forms during fusion. The carpometacarpal joint (CMC) is evident in this close up of an equine skeleton’s left front limb. Using the new, minimally-invasive arthrodesis procedure, Dr. Luca Panizzi inserted a drill bit into the joint space through two different entry points and drilled three tracts to destroy some of the cartilage and bone — but only enough to encourage fusion. PANIZZI IN PROFILE: Hailing from Italy, Dr. Luca Panizzi graduated from the University of Parma’s veterinary program in 2003. His next move was to the United States where he completed internship and fellowship programs at Chino Valley Equine in Chino, Calif. In 2006, Panizzi came north to Saskatoon, Sask., to begin a three-year Master of Veterinary Science program and a large animal surgery residency in the Western College of Veterinary Medicine’s Department of Large Animal Clinical Sciences. The talented graduate student was also selected as one of the Equine Health Research Fund’s 2006-07 Research Fellows — a honour that has been renewed for the past two years. While he’s never actually owned a horse, Panizzi says he’s always been drawn to working with them: “When I was a kid, my father took me to a racetrack one Sunday and I fell in love right there.” Panizzi says he’s learned a lot during his time at WCVM and has appreciated working with Dr. Spencer Barber, one of the veterinary college’s longtime equine surgeons and Panizzi’s graduate supervisor. “I was more than happy to start this project because orthopedics is one of my main interests, so I was really interested when he proposed this to me.” While Panizzi has enjoyed his time in Saskatchewan, he admits that he finds winters last a little too long for his taste. Last year, Panizzi had first-hand experience with the power of Prairie storms when the student’s flight from Italy was diverted to Regina because of Saskatoon’s memorable blizzard on January 10, 2007. After renting a van, Panizzi and other travellers tried to drive home but the bad weather finally forced them to spend the night in Davidson, Sask. Storm-stayed — another western Canadian experience that Panizzi won’t soon forget. Western College of Veterinar y Medicine 9 When veterinary ophthalmologist Dr. Lynne Sandmeyer began her investigation of congenital stationary night blindness (CSNB) in Appaloosa horses nearly three years ago, there was plenty of speculation, theories and anecdotes that associated the disease to particular coat patterns in the Appaloosa breed — but not much else in terms of solid veterinary research. Now, findings from the Western College of Veterinary Medicine (WCVM) study show a definite association between the eye disease and the Lp (leopard complex) gene that’s responsible for “turning on” the breed’s spotting coat patterns. The study results were published in the November 2007 issue of Veterinary Ophthalmology.* “All 10 of the homozygous Lp (few-spot or snowcappatterned) horses in our study have been diagnosed with CSNB, but none of the other horses has the disease,” reports Sandmeyer, an associate professor in WCVM’s Department of Small Animal Clinical Sciences. “It’s a relatively small sample, but the evidence seems conclusive. Whether the problem is with the Lp gene itself or with a nearby gene that’s linked to it — we don’t know that yet.” Sandmeyer and her research collaborators selected 30 purebred Appaloosa horses that displayed three different coat patterns found within the breed to participate in the two-year study. Ten horses had the “few spot” or “snowcap” pattern (homozygous for the Lp gene, or carrying two copies of the gene), 10 animals were “leopard” or “blanket spotted” (heterozygous Lp, or carrying one copy), and 10 were solid-coloured (not carrying the Lp mutation). Sandmeyer thoroughly examined the eyes of all of the horses and conducted electroretinographic (ERG) testing to confirm the presence or absence of CSNB. Tissue and blood samples were also taken from each of the horses. Confirming the association between coat patterns and genetics is just one aim of the study; determining where the problem lies and how to fix it are also important goals of the investigation that’s backed by the College’s Equine Health Research Fund. “The eyes of the affected horses appear completely normal, but the ERG testing shows that there’s a disruption somewhere in the signal transmission. Information is not getting through from the horses’ eyes to their brains,” explains Sandmeyer. Although it’s still not clear where the broken link in the signal transmission occurs, she suspects the problem might be with a receptor, and that transmembrane proteins may be involved. As for other aspects of the study, it will take about a year to complete the immunohistochemical analysis of the horses’ tissue samples — testing that will help to pin down any physiological differences between the eyes of normal horses and the eyes of horses diagnosed with CSNB. Sandmeyer’s CSNB study is part of a much larger, North America-wide initiative called the Appaloosa Project that’s exploring the genetic makeup of the equine breed. Dr. Rebecca Bellone, a genetic researcher from the University of Tampa and one of the Appaloosa Project’s key collaborators, is responsible for analyzing the horses’ blood samples. “We’ll start our investigation into the puzzle at this end, they’ll start at the other, and we hope to meet somewhere in the middle with a few of the answers,” says Sandmeyer. Once researchers have pinpointed what causes the transmission problems and the gene responsible for the disease has been identified and located, then scientists can focus on developing potential gene therapy for CSNB. By Roberta Pattison Research Sheds New Light on Night Blindness 10 Horse Health Lines • Summer 2008 Several types of night blindness have been identified in people, and it’s likely that one or more of these types share similarities with CSNB in horses, says Sandmeyer. “We can learn from the work that’s been going on in human medicine, and they can learn from studies such as ours. Information goes both ways.” Meanwhile, Sandmeyer is interested in examining and identifying other horses afflicted with CSNB. It only takes about 40 minutes to conduct the physical examination and the testing required for diagnosing the disease — and she has already found a few more CSNB-affected horses. She suspects that part of the reason why the disease has gone unnoticed for so long is because it’s seldom diagnosed: many horse owners simply have no idea that their animals can’t see in the dark. “Horses are adaptable creatures, and when they live from birth with a condition like this, they learn to cope. As well, people aren’t around their horses much at night so often aren’t aware that there’s a problem,” explains Sandmeyer, who welcomes inquiries from veterinarians or horse owners about the disease. “This is an important problem that affects probably a quarter of the Appaloosa population. It’s also a manageable disorder. Affected horses get by very well as it is, but once you know your horse has CSNB, you can make life a little easier for him.” H *Sandmeyer LS, Breaux CB, Archer S, Grahn BH. “Clinical and electroretinographic characteristics of congenital stationary night blindness in the Appaloosa and the association with the leopard complex.” Veterinary Ophthalmology. 10(6): 368-375. Visit www.ehrf.usask.ca to view the Fall 2005 issue of Horse Health Lines that includes more background information about WCVM’s investigation of CSNB. Contact Dr. Lynne Sandmeyer for more details (306-966-1336; lynne.sandmeyer@usask.ca). Roberta Pattison is a freelance writer who is a regular contributor to the national publication, Dogs in Canada. Recently retired from grain farming, she still lives on her farm near Delisle, Saskatchewan. Q. Why is equine dentistry such a hot topic in horse health today? I think that’s fueled by the growing interest of horse owners and veterinarians. People now recognize that dental pathology is there, it’s not going away, and it needs to be addressed. In turn, veterinarians are gaining the owner’s acceptance for the need to sedate a horse and do a thorough oral evaluation with a full mouth speculum. Now, it’s just not enough to pull the tongue to the side and take a quick look anymore: people now appreciate why it’s just as important to examine the horse’s mouth as it is to examine any other part of its body. Q. What’s the most significant change that you’ve seen in equine dentistry during the past decade? Straight from the Horse’s Mouth A Specialist’s View on Equine Dentistr y in Wester n Canada Dr. James Anthony is a 1983 graduate of the Western College of Veterinary Medicine and a diplomate of the American Veterinary Dental College — the certifying organization for North American veterinary dentists. Since joining WCVM’s faculty in 2006, Anthony has provided referral and clinical services in veterinary dentistry to a wide range of small animal and large animal patients at the College’s Veterinary Teaching Hospital. He also offers advanced training to undergraduate students and practising veterinarians, and he will soon implement Canada’s first accredited residency program in veterinary dentistry. As a veterinarian with more than 20 years of experience in veterinary dentistry, Anthony offers a unique perspective on issues related to this specialized field, the growing recognition of dentistry’s importance in equine health — and a glimpse of its future. The biggest change is that veterinarians are now taking a real good look in the horse’s mouth: they’re conducting oral examinations and recognizing what’s normal and reporting what’s abnormal. Simple things like having more specialized equipment available for equine dentistry have made that possible: besides the traditional full mouth speculum, we now have dental mirrors, dental probes, dental picks, some of the newer extraction forceps and elevators, plus equipment for root canals in equine teeth. These tools have really come along in the last few years, and it’s made life a lot easier for veterinarians. Q. What about technology: what’s the most important development? I would say it’s the advances that have been made in dental radiography for small animals and horses. Dental radiographs are imperative for visualizing lesions and planning treatments. Without them, you’re using insufficient data to develop a treatment plan, so that’s why they’re really the foundation of your examination. With the advent of computerized radiographs, it’s actually become affordable for veterinarians to conduct and produce dental radiographs. That’s why I think we’ll see more and more veterinarians using dental radiography for their equine patients. In the past, there were dangers related to sedatives that are necessary for taking dental radiographs. But with the introduction of better, faster and safer drugs, the incidence of adverse reactions is much, much lower. An experienced veterinarian will be on alert for any problems and have all of the precautions ready for those types of situations. Q. What do you think horse owners want when it comes to equine dentistry? I think people are demanding that dental practices be evidence-based. They want to use practices that are proven scientifically sound instead of just relying on hearsay or anecdotal evidence. Western College of Veterinar y Medicine 11 Veterinary Medicine’s Equine Health Research Fund that supports equine health research projects addressing critical health issues in the horse industry. Q. How is veterinary dentistry education changing at WCVM? Beginning next year, our veterinary students will have even more training in veterinary dentistry than they currently receive. During the students’ second year at WCVM, we’ll focus on teaching them the principles and fundamentals of veterinary dentistry so they’re capable of working with any species — everything from dogs, cats, horses and cattle to exotic species and wildlife. It’s the most extensive dentistry program in the world as far as the number of teaching hours and the time spent in hands-on laboratories. Plus, the students will also have the option of taking further dental rotations in their senior year to focus even further on the discipline before graduation. EQUINE DENTAL RESEARCH DOLLARS: Investigating the incidence of oral pathologic conditions in horses is a topic that’s high up on Dr. James Anthony’s (above) research priority list. Last fall, that research goal received a boost when Anthony and his co-investigator, Dr. James Carmalt, received a $5,000 research grant from the Peter Emily International Veterinary Dental Foundation that supports research initiatives in veterinary dentistry. Anthony accepted the research award during the annual Veterinary Dental Forum that was held last October in Minneapolis, Minn. Besides accepting funding, Anthony also presented two papers at the Forum: one on the problem of “furcation” (the area where roots join the crown in a tooth with multiple roots) and the other on a new crown design to enhance retention. Q. What are key areas where more research is crucial? The challenge is that right now, we really don’t have a true grasp on the incidence of oral pathologic conditions of the horse, and that’s why an incidence study of oral pathology in horses is at the top of my list. Developing new types of equipment and testing better ways of doing certain procedures would be another key research area. For example, we need to develop some proper instruments for extracting horses’ teeth. Another area where we need further research is dealing with tooth loss in horses. A big problem with horses — or any type of herbivore species — is that when they lose a tooth, other teeth move into the open space causing “collapsing of the arcade.” We need to try and find a way to stabilize the remaining teeth while still having a functional mouth. Q. What are the pitfalls of conducting dentistry research? Clinical studies can be very challenging to do, plus the investigations are not cheap. The main concern is that you have to compare “apples to apples”: you need to ensure that there are no other causes of the specific oral problems in the equine cases that are participating in the study and no other influences on the research. One source of veterinary dentistry research funding is the Peter Emily International Veterinary Dental Foundation that awards annual research grants to researchers. Another potential source is the Western College of 12 Horse Health Lines • Summer 2008 Q. As equine dentistry gains acceptance, how will health care teams evolve? I think the growing awareness of equine dentistry has already helped most veterinarians appreciate the need to add to their existing knowledge of the discipline through continuing education. For some, it’s also underlined the value of referring certain patients on to someone who specializes in veterinary dentistry and can address specific problems. Ultimately, the goal is to ensure that all dental procedures in horses are done correctly and safely, and I think that future includes qualified lay equine dentists. However, they also have to realize their limitations. They can have a lot of knowledge about basic procedures in oral hygiene, but they don’t have the specialized training in the discipline and in veterinary medicine to resolve an unexpected problem or to reduce the pain and trauma for a patient. What I foresee is a system similar to human medicine where dentists work closely with dental hygienists in their clinics. Lay dentists will do oral hygiene procedures, teeth floating and other procedures, but their work will be under the supervision of a veterinarian who ensures the patients’ safety at all times. If we work together for the common good of our patients, I think everyone is going to benefit. Q. What’s your vision of equine dentistry in 10 years? By 2018, equine dentistry will be at the same level as small animal dentistry: it’s been growing by leaps and bounds and the amount of knowledge is increasing exponentially. One of the main reasons is that as we treat these animals, the horse owners and their veterinarians see the true benefits of the treatments and they’re recognizing that oral pathologies are a real problem. It’s not some kind of marketing scheme, but rather, it’s a reality that will benefit the whole horse and ultimately benefit the owner and rider since the treatments can increase a horse’s performance level. I’ve had many, many clients tell me, “I never even realized how much my animal was suffering until I saw the response after the procedure was done.” That’s become a very common statement from owners of small animals as well as large animals, and to me, that’s why veterinary dentistry is such a great profession. The results are almost instantaneous, and it’s very gratifying to see the difference you can make. H S t u d e n t s Sink Teeth into Equine Dentistr y In late January, a group of equine-minded veterinary students at the Western College of Veterinary Medicine (WCVM) spent an entire Saturday polishing up their knowledge of equine dentistry. Organized by the WCVM student chapter of the American Association of Equine Practitioners (or the WCVM Equine Club), the one-day event included a morning lecture by Dr. James Carmalt, an associate professor of large animal surgery who has clinical and research interests in equine dentistry. More than 70 students from all class years attended Carmalt’s four-hour lecture that gave a comprehensive overview of horses’ oral anatomy and common pathologic issues, dental therapy techniques and oral management. After lunch, about 30 third-year veterinary students participated in an equine dentistry wet lab that began with a hands-on training session in the college’s anatomy lab. With the help of large animal clinicians and residents, the students practised their oral examination skills and manual floating techniques on equine cadavers. Afterwards, the group moved to one of the college’s barns where clinicians demonstrated sedation, power floating and oral examination methods on live horses. During lab’s final two hours, the students had the chance to work with the sedated horses and hone their skills with the help of faculty and residents. While the equine dentistry lab has been an annual event for the past few years, this was the first time that the Equine Health Research Fund invested $2,500 in the student-organized activity. The Fund helped to pay for the day’s expenses and resources as well as refreshments for the morning’s coffee break. The students’ equine dental lab fits in well with the EHRF’s mandate to support veterinary training in equine-related health care. The financial support also recognizes the valuable contributions that members of the WCVM Equine Club make to the Fund’s activities and events throughout the year. H Top left: Dr. Steve Manning steadies a sedated patient while resident Dr. Kristin Poirier demonstrates the use of a PowerFloat®. Above: Veterinary student Tamara Quaschnick peers into a horse’s mouth. Centre: Resident Dr. Nathalie Tokateloff holds up a horse’s lip so students can get a better view. Western College of Veterinar y Medicine 13 Key Facts about Equine Herpes Virus During an EHV outbreak, knowledge and awareness are powerful tools in controlling the spread of the virus among horse populations. Q. What is equine herpes virus and EHV-1? Equine herpes virus is a common virus that occurs in horse populations worldwide. One of the virus’ most common strains is equine herpes virus type 1 (EHV-1) that’s known to cause respiratory diseases as well as outbreaks of abortions and neurologic disease. Q. Which horses are most susceptible? The respiratory disease caused by EHV is most common in weanlings and yearlings. Older horses are more likely to transmit the virus without showing clinical signs. Q. What are the clinical signs? Fever commonly precedes other clinical signs, but it may be the only sign of infection. Other potential clinical signs include respiratory disease: fever, coughing and nasal discharge. Abortion is another potential sign: abortions caused by EHV typically occur late in pregnancy, often without warning signs. Neonatal foals may be infected in utero and are usually abnormal from birth. Weakness, jaundice, respiratory distress and neurologic signs are among the clinical signs. Affected foals typically die within several days. Older infected foals generally have nasal discharge or other signs of respiratory disease. Q. What is EHM? Equine herpesvirus myeloencephalopathy (EHM) is another name for the neurologic disease caused by EHV-1 infection. It results from widespread damage to blood vessel endothelium (lining) — including damage to the blood-brain barrier. EHM can cause single cases of disease, but it has also been identified as a cause of outbreaks affecting 20 to 50 per cent of affected populations. EHM outbreaks may or may not be associated with previous or concurrent respiratory disease. Q. What are the clinical signs of EHM? Neurologic disease may be preceded by fever and respiratory signs. EHM typically affects the hind limbs and urinary tract. Common signs include inco-ordination, urinary incontinence and bladder distension. Severely affected horses may become recumbent and unable to rise. “Dog-sitting” may be observed. Horses generally remain bright and often continue to eat and drink. Q. How is EHV infection diagnosed? Veterinarians often suspect the disease based on clinical signs, but it’s recommended that further testing (serology, virus isolation and molecular testing) be done to establish the diagnosis. Q. What’s the treatment for EHM? • Treatment is mostly supportive and includes anti-inflammatory medication such as corticosteroids. Some horses may require IV fluid therapy. • Place affected horses in a safe, well-bedded stall, especially if they’re severely unco-ordinated and have trouble rising. Recumbent horses may benefit from the use of a sling. • Horses that have difficulty urinating may need to be catheterized several times daily and may benefit from medication to support bladder function. • Specific treatments directed against the virus are under investigation. Preliminary research suggests a potential benefit of antiviral medications such as acyclovir and valacyclovir. Q. What’s the prognosis? While the prognosis is generally favourable for mildly affected horses, the outcome is poor for those that become recumbent for prolonged periods. It may take several weeks to months before neurologic deficits resolve in recovering horses, and some may have persistent deficits for the rest of their lives. Q. How long are affected horses still infectious? Q. How is the virus transmitted? Affected horses usually shed the virus for up to a week — possibly longer — after the onset of fever or neurologic disease. Infected animals typically develop latent infections, and they can shed virus with or without showing signs of the disease for the rest of their lives. Latently-infected horses typically shed the virus during periods of stress, and re-activation of the virus is responsible for the spread and survival of the virus in horses. This also provides a logical explanation for occasional outbreaks observed in isolated herds. • Aerosol: The virus is primarily transmitted by aerosol (inhalation of infectious droplets from coughing and snorting) and through direct and Q. Can owners vaccinate horses against EHV? Q. What’s the virus’ incubation period? While the time between infection and onset of clinical signs can be as short as 24 hours, the incubation period typically lasts between four and six days — and can extend longer. EHV abortions can occur from two weeks to several months following infection. 14 indirect contact. Shedding by the respiratory route typically lasts for seven to 10 days but can persist longer. • EHV-related abortions: Aborted fetuses, fetal membranes and fetal fluids are infectious. Mares that have aborted also shed virus in their respiratory secretions. • Indirect transmission: The virus can be indirectly transmitted between infected and uninfected horses when nasal secretions or fluids from abortions are moved via people or inanimate objects. • Poor hygiene: A lack of handwashing and sharing of equipment can potentially transmit the virus to uninfected horses. People who are in contact with infected horses should change their clothes and thoroughly clean and disinfect their hands before handling other horses. Horse Health Lines • Summer 2008 Several vaccines against EHV are available. Vaccination should be based on the perceived risk of infection, but it’s generally recommended for broodmares. Horse owners should talk to their veterinarians about vaccination programs. Horse owners and veterinarians can also consult the American Association of Equine Practitioners (AAEP) vaccination guidelines. None of the currently available vaccines states any claim for protection against the neurologic form of EHV infection. Q. Can vaccines prevent further cases during an EHV outbreak? The benefit of vaccination in the face of an outbreak is questionable. Booster vaccination may reduce virus spread and it hasn’t been associated with detrimental effects. Q. What can I do to control EHV’s spread? • If you suspect your horse is infected with EHV, ask your veterinarian to examine your horse and conduct appropriate testing. • Isolate any infected horses immediately and avoid all direct and indirect contact with other horses. Exposed horses should also be isolated as a precautionary measure. • Stop all horse traffic on and off premises where infected horses have been identified. • Isolate infected and exposed horses from the general population for 28 days following the onset of the last identified case. Veterinarians can conduct testing to determine whether horses are still shedding the virus. • Pay strict attention to hygiene and wash your hands properly. Q. What should be done after an EHV outbreak? To prevent further cases, it’s important to thoroughly clean and disinfect your facilities and all equipment. EHV is susceptible to many disinfectants, but as a precaution, read the information provided with disinfectant products or contact the manufacturers. Before disinfecting your facilities, make sure to remove manure, nasal secretions and other organic materials from the site. Q. How can you prevent EHV outbreaks? Boarding facilities, show grounds, auction barns and other public facilities should discuss biosecurity with their attending veterinarian and develop a biosecurity protocol specific to their situation. Biosecurity measures include isolation of new horses upon arrival, testing of new horses upon arrival, and requirements for health certificates and/or vaccination. Original source: American Association of Equine Practitioners (www.aaep.org), with additional information provided by Dr. Katharina Lohmann, Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine (www.wcvm.com). Spring 2008: EHV-1 Outbreak Early this spring, an outbreak of equine herpes virus type 1 (EHV-1) in the Saskatoon area put horse owners across the province on alert and caused WCVM’s Veterinary Teaching Hospital to suspend its regular equine clinical services for 29 days. By mid-April, WCVM veterinarians believed that more than 100 horses at two farms in the Saskatoon area had been exposed to the virus in the previous four weeks. About 20 per cent of those horses developed clinical signs of the neurologic form of EHV-1, and one horse was euthanized due to severe neurologic signs. During the outbreak, WCVM teamed up with the Farm Animal Council of Saskatchewan Inc. (FACS) to organize an EHV information seminar for Saskatoon-area horse owners on April 10. The same partners, along with the Saskatchewan Veterinary Medical Association, organized a second seminar for southern Saskatchewan’s horse community on April 22 in Regina, Sask. During both sessions, a combined total of more than 400 horse owners learned the facts about EHV-1 from infectious disease specialist Dr. Hugh Townsend. As Townsend pointed out in his presentations, the percentage of horses affected by the neurologic form in the Saskatchewanbased outbreak is very similar to what has been seen in other outbreaks of EHV-1 throughout North America. “EHV-1 is not a new disease: we’ve seen it for many years. Based on the numbers that we have for this outbreak, it does not seem that our situation is different or more severe than what has been seen in other situations,” said Townsend, a professor in WCVM’s Department of Large Animal Clinical Sciences and a senior research scientist at the Vaccine and Infectious Disease Organization (VIDO). Townsend added that there’s no scientific evidence indicating that recovered horses increase the risk of EHV infection to other horses. “Extrapolating from studies conducted in the United States, it seems likely that about 10 per cent of the horses in Saskatchewan carry the neurotropic strain of EHV-1, and have probably done so for many years. Currently, there is no evidence to suggest that these horses should be treated or managed differently from any of their herdmates.” Photo: Adele Buettner, Farm Animal Council of Saskatchewan Western College of Veterinar y Medicine 15 GALLOPING GAZETTE NEW HOSPITAL DIRECTOR: Dr. Jacques Messier took over the reins of director at WCVM’s Veterinary Teaching Hospital on April 21. Messier, who earned a Doctor of Veterinary Medicine at the Université de Montréal’s Faculté de médecine vétérinaire and an MBA from the University of Western Ontario, brings a range of management training and experiences to his new role. Early in his career, Messier practised veterinary medicine in Saskatchewan for six years before joining Agriculture and Agri-Food Canada where he held several management positions including the Bureau of Veterinary Drugs and the Bureau of Human Prescription Drugs. In the private sector, Messier has been part of the senior management team for several large pharmaceutical and biotechnical companies — including president, COO and CEO of an international pharmaceutical manufacturer and distributor. Dr. Klaas Post, head of WCVM’s Department of Small Animal Clinical Sciences, has been WCVM’s acting hospital director since the former director, Dr. Stan Rubin, rejoined the veterinary college’s faculty during the summer of 2007. CLINIC UNDERGOES REVAMP: In April 2008, crews began renovation work in the WCVM Large Animal Clinic. The construction project includes renovations to the clinic’s surgery suites and equine ward as well as to other services in the clinical area. The construction work, which is scheduled for completion in early 2009, will not affect the clinic’s regular services. Watch for a construction update in the Autumn 2008 issue of Horse Health Lines. EQUINE PATIENT ADVOCATE: Dr. Kirby Penttila of Chase, B.C., a member of WCVM’s Class of 2008 and a newly-minted Doctor of Veterinary Medicine, was the 2008 recipient of the Dino and Dr. Ashburner Award in Equine Care at WCVM’s 2008 Graduation Banquet on May 28. Penttila received the $7,000 award in recognition of her care for equine patients during the veterinary student’s fourth-year equine rotations. The annual scholarship was created in 2007 by the Heather Ryan and L. David Dubé Foundation. EQUINE CONTENT IN LAVR: Large Animal Veterinary Rounds is a WCVM-led publication that provides valuable veterinary resources to Canada’s large animal practitioners. Some of its latest editions focused on equine-related health issues: • “Minimally invasive surgery in the horse,” by Dr. David Wilson, head of WCVM’s Department of Large Animal Clinical Sciences. 8(2). February 2008. • “Equine field anesthesia and sedation,” by Dr. Nigel Caulkett, Department of Clinical and Diagnostic Science, Faculty of Veterinary Medicine, University of Calgary. 7(9). November 2007. • “Diseases affecting the geriatric horse,” by Dr. Katharina Lohmann, Department of Large Animal Clinical Sciences, WCVM. 7(7). September 2007. For more information or to download your own copies of these issues (in PDF format), visit www.canadianveterinarians.net/larounds. Above: Rocky Ridge Clydesdales of Odessa, Mo., win the eight-horse hitch class at the 2008 Royal Manitoba Winter Fair in Brandon, Man. V i s i t H o r s e H e a l t h L i n e s o n l i n e a t w w w. e h r f. u s a s k . c a WCVM PRESENTS: Several WCVM representatives gave scientific presentations at recent international equine health meetings: • Equine reproduction specialist Dr. Claire Card gave a presentation on “GnRF immunization in mares: ovarian function, return to cycling and fertility” at the American Association of Equine Practitioners’ annual convention. The 53rd convention took place in Orlando, Fla., from Dec. 1-5, 2007. • Large animal surgery resident Dr. Ryan Wolker presented his abstract, “A biomechanical comparison of two parallel AT screws and two parallel 5.5 mm bone screws for equine proximal interphalangeal joint arthrodesis,” at the Veterinary Orthopedic Conference. The meeting took place in Big Sky, Mont., from March 8-15, 2008. • In late April, equine surgeon Dr. David Wilson and clinical associate Dr. Joe Bracamonte presented a short course on laparoscopy during the “Cirso Internacional de Laparoscopia Equina” (International Conference on Laparascopy in the Horse) in Caceres, Spain. The course included two days of instruction and a one-day wet lab for participants. FUND GOES TO MANE EVENT: Are you heading out to the 2008 Mane Event Equine Education and Trade Fair this fall? So are we! Make sure to stop in at Booth #905 on Hoofbeat Way where representatives from WCVM and the Equine Health Research Fund will be happy to tell you more about the College’s equine health initiatives and to answer your questions about the Fund and WCVM. The Mane Event takes place from October 17-19, 2008, at the Chilliwack Heritage Park in Chilliwack, B.C. For more details, visit www. maneventexpo.com. 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