WCVM’s matching gift program doubles the impact of a $10,000 gift from the Equine Foundation of Canada. E I N S I D E 4 Idea Expands into New Technique EHRF Research Fellow Dr. Chris Bell and summer research student Dane Tatarniuk transform an idea into a new, minimally-invasive treatment for sinusitis. 6 Anatomy Project Goes Live A basic anatomy project turned into a golden opportunity for EHRF summer research student Dane Tatarniuk. 8 The Future’s Bright for Horse Health Care Meet three young veterinary students at the WCVM who represent the future of horse health care in Western Canada. 10 EHRF Studies Build on Research Experience EHRF invests $69,000 in five WCVM equine health research projects. 12 Horse Health Care Through the Ages Tips on how you can keep your older horses healthy and happy. 14 Lasting Value Paint breeder Shirley Brodsky talks about the health and care of Double Value, her 25-year-old broodmare. FRONT COVER: Large animal surgery resident Dr. Chris Bell of Airdrie, Alta. Bell is one of three EHRF Research Fellows at the WCVM. ABOVE: A curious colt at Jack and Shirley Brodsky’s farm near Saskatoon, Sask. Foaled by Jackie on April 7, the palomino Paint’s sire is Far Ute Finale (Finnegan). H O R S E H E A L T H L I N E S Horse Health Lines is produced by the Western College of Veterinary Medicine’s Equine Health Research Fund. Visit www.ehrf.usask.ca for more information. Please send comments to: Dr. Hugh Townsend, Editor, Horse Health Lines WCVM, University of Saskatchewan 52 Campus Drive, Saskatoon, SK S7N 5B4 Tel: 306-966-7453 • Fax: 306-966-7274 wcvm.research@usask.ca For article reprint information, please contact sm.ridley@sasktel.net. ldon Bienert remembers the early days of the Equine Foundation of Canada when Nova Scotia horseman George Wade and a small band of volunteers from across the country regularly met in the early 1980s to set up the fledgling charity. Wade, a successful Nova Scotia businessman and Morgan horse breeder, had a simple but ambitious dream for the organization: he wanted the EFC to improve the health and welfare of all horses — no matter what breed — across Canada. That dream has led to more than $230,000 in support for veterinary scholarships, research grants and the purchase of medical equipment over the past 25 years. The money has been spread across the country through the foundation’s rotation of annual donations among Canada’s veterinary colleges. “I always said to George, ‘This is something that we gotta carry on.’ And George said to me, ‘Well, when I’m gone, it’s something that you gotta carry on,’” said Bienert, a Morgan horse breeder from Leduc, Alta. “And that’s what happened. I couldn’t go back on my promise.” But keeping that promise to his longtime friend wasn’t always easy. After Wade died in 1997, Bienert, his wife Peggy MacDonald and others struggled to keep the foundation afloat and to attract more interest among Canada’s horse owners. “You have your lean years and you have your good years,” said Bienert, who became the foundation’s president after Wade’s death. Last year was one of the EFC’s good years. Through several fundraising trail rides in Alberta and Saskatchewan, along with a generous gift from the Alberta Trail Riding Association, the foundation raised $10,000 for the Western College of Veterinary Medicine’s equine health research program. For Bienert, things got even better when he learned that the EFC gift met the requirements for the college’s matching gift program. Developed by the Heather Ryan and L. David Dubé Foundation, the Saskatoon-based organization will match any new or increased donations to the WCVM’s equine research programs between 2006 and 2011. In its first two years, the program has already helped to raise more than $300,000 in increased funding for the WCVM’s horse health activities. “We think the matching gift program is just wonderful news, and we’re very pleased that our donation will bring additional money to the WCVM’s horse health research projects. It makes all of the hard work of organizing our fundraisers throughout the year even more worthwhile for our supporters,” said Bienert. The new funding will support the WCVM’s ongoing research investigations of equine sarcoids — the most commonly diagnosed skin tumours in horses around the world (see sidebar). “We’re extremely grateful to the hundreds of horse owners and enthusiasts across Canada who worked together through the EFC and raised this significant donation for the College’s horse health research program,” said WCVM Dean Dr. Charles Rhodes. “The EFC’s long-standing commitment to enhancing the health and welfare of all horses is an impressive example for the country’s entire horse industry.” The gift is the largest that the EFC has ever presented to the WCVM since the national charity was created in 1983. Altogether, the foundation has contributed nearly $42,000 to the WCVM for equipment purchases and research grants, plus it has provided $20,000 worth of scholarships. owners can raise money for the EFC by participating in trail rides in Nova Scotia, Ontario, Manitoba, Saskatchewan, Alberta and B.C. “We usually head out at 1:30 p.m., ride for a couple of hours and then come back for a big potluck supper. We always have lots of good food — it makes an enjoyable evening for everyone,” says Bienert, whose enthusiasm for the volunteer-run foundation hasn’t waned during the past quarter century. He’s also proud of the fact that 94 per cent of every dollar raised through the EFC goes directly to support horse health and welfare. “A lot of horse people don’t know about the Equine Foundation of Canada, so if we just take the time to explain what we do and why we do it, the light usually comes on. We just need to make people aware of why it’s important to take care of our horses.” For more information about the EFC and upcoming fundraising events, visit www.equinefoundation.ca. H A Perfect Match “The WCVM was our very first recipient of a whopping $500 in 1984. Over the years, we’ve just been giving and you’ve been giving back,” EFC vice president Charlene Dalen-Brown told a group of WCVM representatives and researchers during the cheque presentation at the veterinary college on April 24. “Twenty-five years — that’s how long the Foundation and the WCVM have been in partnership. We’re helping you and you’re helping our horses — so thank you.” While Dalen-Brown was celebrating the EFC’s latest donation at the WCVM, Bienert and MacDonald were already talking about the foundation’s next season of fundraisers with visitors at the Mane Event in Red Deer, Alta. This summer, horse SARCOIDS, WESTERN CANADIAN STYLE: The Equine Foundation of Canada’s gift, along with the matching funding, will help to support an investigation of equine sarcoids — common skin tumours that can seriously impair a horse’s comfort and performance. Led by Dr. Andy Allen of the WCVM’s Department of Veterinary Pathology, the study is a continuation of work that began two years ago when Allen, PhD student Dr. Bruce Wobeser and veterinary pathologist Dr. Beverly Kidney set out to answer some of the unknowns about sarcoids and to develop a western Canadian “profile” of the tumours. The team is still analyzing more than 800 biopsies of sarcoids from horses in Alberta, Saskatchewan and B.C., but based on preliminary findings, their results may demonstrate some regional variations in sarcoid epidemiology. One difference may be in the breeds that are most susceptible to developing equine sarcoids in Western Canada. Another regional distinction showed up when researchers looked at the link between sarcoid development and a common cattle virus called bovine papillomavirus (BPV). In the majority of existing research, BPV-1 is the most commonly found virus in about 80 per cent of sarcoid samples taken from horses in Europe and the eastern U.S. In contrast, the WCVM research team found that in sarcoids from which BPV DNA was recovered, 80 per cent was BPV-2 while only 20 per cent was BPV-1. These results are similar to what researchers have found in equine sarcoid samples taken from horses living in the western U.S. ABOVE, left to right: Dr. Gillian Muir, WCVM’s acting associate dean of research, EFC supporters Laurie Friesen and Sharon Elder, researchers Drs. Janet Hill, Bruce Wobeser and Andy Allen, EFC supporter Anita Zadorozny, researchers Dr. Beverly Kidney and Betty Chow-Lockerbie, Dr. David Wilson, WCVM Equine Health Research Fund chair, EFC supporter Nicole Shedden, WCVM Dean Charles Rhodes, EFC vice president Charlene Dalen-Brown and her husband, Bill Brown. In a second study, the team developed immunohistochemical techniques to demonstrate markers of apoptosis (programmed cell death) in archived tumour tissue samples. Based on recent research in human cervical cancer, which is also caused by a papillomavirus, the expression of apoptosis markers can be useful to determine the prognoses of these tumours. WCVM researchers are working to find similar diagnostic markers in equine sarcoids. Now, microbiologist Dr. Janet Hill and lab technician Betty Chow-Lockerbie are joining the original research team for a third study — one that will use molecular techniques to further explore the role of BPV in the growth of equine sarcoids. Based on recent studies, BPV may also play a role in inflammatory skin lesions and non-sarcoid neoplasms — a possibility that the WCVM researchers wants to investigate in western Canadian horses. Based on their findings, the team hopes to develop more effective methods of diagnosing the skin tumours and to eventually find better strategies for treating the disease. Visit www.ehrf.usask.ca for more background information about the College’s equine sarcoid investigations. Western College of Veterinar y Medicine 3