Anatomy of a research paper Dario M Torre, MD,MPH, PHD Associate professor of medicine Drexel University College of Medicine Objectives Learners will be able to: ◦ Describe key elements of the research question ◦ Identify the main sections that constitute a research paper ◦ Recognize factors related to the submissionreview process Element of a Research questions: FINER Feasible Interesting Novel Ethical Relevant Hulley SB and Cummings SR. Designing Clinical Research 1988. FINER Feasible -affordable in time, money, resources -manageable in scope -adequate number of subjects -adequate technical expertise FINER Interesting to the researcher to other stakeholders(medical educators, administrators) to the outside academic and non academic world FINER Novel -confirms or refutes previous finding -expands previous findings -provides new findings FINER Ethical -pose harm to the participants, invasion of privacy - violates confidentiality - IRB!! FINER Relevant contributes to the literature, advances scientific knowledge may change current ideas or practice potential to develop further projects Retrieve the components of Research question!!! FINER Feasible Interesting Novel Ethical Relevant Operationalize the research question Review the literature Capitalize on what you do Identify a problem in your clinical practice, QI, course or fellowship Implement and assess a possible solution create a new program and assess feasibility or outcomes National & International meetings ◦ Formal presentations, informal discussions with colleagues Operationalize the research question Peruse the literature; why is that important? ◦ Your question might have been already answered ◦ No literature has addressed the proposed question ◦ Additional research questions may be identified building upon other research ◦ Another researcher may have used a particular methodology for a similar question Research question: few tips! Formulation of a clear and concise research question is the most difficult step of your research project yet the most important You might decide to answer more than one research question however …FOCUS!!! Discuss your research questions with peers, mentors, or experts Some research questions may not require new data to be generated (however it may hinder the quality of the question, or create limitations for your project ) So ASK yourself Would anyone care whether I answered this question/solved this problem? Is it framed as a question; can it be answered? Has it been studied before? Does it pose risks or invasion of privacy? Does it matter? Will it advance educational knowledge and practice? Use the worksheet and write a research question 5-10 min Research Hypotheses Written as a statement of prediction about the specific relationships that are studied or expected outcomes. Structure of the paper 1. Introduction 2. Methods 3. Results 4. Discussion The Introduction The problem supported by few key refs, the current status (What is known) Importance of the problem, gaps in current knowledge (set up your “so what early”) Justify the need for the study Hypothesis, Research question and Purpose The Introduction The introduction builds a logical case and an appropriate context for the statement of the problem and purpose It orients the reader to the topic of the paper Moves logically from the known to the unknown McGaghie et al, 2001 Statement of purpose Written as a statement of intent (purpose)summarizing key elements of the study. ◦ The purpose of this study is to assess whether students who do attend case-based discussions achieve higher scores on the NBME Self Exam in Internal Medicine when compared to students who do not. Methods Reader should be able to replicate the study Describe in detail how the study was performed Describe variables and how they were measured Describe data collection and measurement instrument/s Methods Study population and setting Study design Data collection Data measurement Outcomes Data analysis Methods Study population and setting ◦ Describe the population studied, sampling method, setting where the study was performed ◦ Think that the reader or reviewer need to understand what/why/how you select the population and the setting Methods: study design articulate the link between research question/purpose and study design Study design may be: ◦ ◦ ◦ ◦ ◦ ◦ Meta analysis or SR RCT Case-control Cohort study Observational Case report Data collection Specify population and sampling ◦ 5 sampling methods : random, simple, systematic, stratified random, and cluster. Locate or develop an instrument to collect data ◦ Is the instrument valid and reliable? ◦ Is there an already validated instrument? Ask for permission Data measurement Measurement instrument Test: knoweldge-based test, labs, imaging study, procedure, etc.. A validated questionnaire, rubric Assess issues of validity and reliability Consider using a previously validated instruments Results Include only data ,not background or methods ◦ State findings without interpretation Start with descriptive data then univariate and multivariate results(if quantitative) Provide data relevant to the research question and purpose of the study Results Use tables and figures sparingly: ◦ ◦ ◦ ◦ do not repeat what is in the text use to present complex data Table 1 usually is baseline characteristics Table 2-3 Regher, 2001 Who is he? Giacomo Puccini, 1858-1924 Discussion The organization of the Discussion section should match the structure of the results section to present a coherent interpretation of data and methods. Discussion State the main findings of the study ◦ First paragraph Explain meaning of your results Discuss and interpret results ◦ Cite appropriate references ◦ May need to explain unexpected results Discussion(cont) Include limitations ◦ Every study has limitations ◦ Acknowledge limitations of the study ◦ Assess whether they are fatal ◦ Limitations may be addressed as needs for future research Discussion Keep in mind the research question Summarize your study findings Do not repeat the intro Novelty of your findings, compared to other literature(be selective with the literature) Do not overstate the results !!! Compare and contrast with other studies Acknowledge limitations before the reviewers do!! Summarize the potential significance of your findings and changes your study may support Few tips : submission and review process Look at the type of articles published by the journal you are planning to submit. Would they be interested? Read instructions for authors: Cover letter, abstract, text, figures and tables ◦ Use a software for refs format Grammar , spell check…don’t upset the reviewers!! Discussion Establish the novelty of your findings The conclusions follow from the design, methods and results If appropriate state the implications Conclude by making a point in relation to the main finding Few tips : submission and review process Make sure the journal is peer reviewed Look at their Impact Factor ◦ A journal's impact factor is a measure of the frequency with which an average article in a journal has been cited in a particular year Med Ed Health Prof journals Medical Education and Health Professions Education Journals Academic Medicine (3.524) Advances in Health Sciences Education: Theory and Practice (2.089) Advances in Physiology Education (1.547) BMC Medical Education (1.15*) Canadian Medical Education Journal (6.4) Clinical Teacher (0.443*) Education for Health: Change in Learning & Practice Evaluation & the Health Professions (1.231) Focus on Health Professional Education (0.882*) Journal of Advances in Medical Education and Practice Journal of Cancer Education (0.762) Journal of Continuing Education in the Health Professions (1.521) Journal of Graduate Medical Education Medical Teacher (1.217) Journal of Surgical Education (1.376) Journal of the International Association of Medical Science Educators Medical Education (3.5) Medical Education Development Medical Education Online http://www.med.uottawa.ca/aime/eng/journals.html Summary The research question: ◦ Identify a problem, review the literature, develop your research question, look at what you do!! ◦ Don’t forget the so what?? Introduction: ◦ justify the need for the , state clearly why the answer to this questions is important ◦ State the purpose clearly Summary Methods ◦ Select the appropriate approach(quantitative vs. qualitative) to answer the research question ◦ Explain what you did and how ◦ Follow a framework Study population and setting Study design Data collection Data measurement Outcomes Data analysis Summary Results State the main finding/s first Provide data relevant to the research question Do not interpret your finding in this section Start with descriptive data then univariate and multivariate results(if quantitative study) Integrates tables and figures with the text Summary Discussion Summarize your findings first Interpret the meaning of your findings and compare to most updated literature Do not forget limitations Do not overstate your results State conclusion, implications, future research Questions!