General Information Page 1 of 2
MBV4120/MBV9120 - Eukaryotic genes and genomes
Spring 2016
General information
Thefirstlecturestarts09:15andendatlatest12:00.
Allotherlecturesstartat09:15andend11:00
Allcolloquiastartat09:15andendat12:00
Colloquium exercises
ColloquiumexercisesforeachweekarefoundinFronter(fronter.uio.no).Pleasepreparefor
excersises@home.Theexercisesarediscussedduringthecolloquiawhereyouaresubdivided
intosmallergroups.Attheendofeachcolloquiumtheexerciseswillbesummarizedbyall
groupstogether.
Eachcolloquiumgroupwillgiveoralpresentations09:15–15.00inweek7(19.02).
Pleaseseethe“TeachingPlan”andbelowfordetails.
Course material
ThemaintextbookisLewins“Genes”,XIEdition.
AllothercoursematerialisfoundatFronter(fronter.uio.no).
Themandatoryreadinginthetextbookisgiveninthe“TeachingPlan”.
Inadditiontothetextbook,eachlecture/colloquiumisaccompaniedbytwofoldersonFronter
containingsupportingliterature:
• The“compulsory”folderismandatoryreading.
• The“recommended”foldercontainsarticlesprovidingbackgroundandadditionaldepthto
someoftheaspectscoveredinthelectures.Thesearticlesarenotmandatory.
Oral presentations
Theoralpresentationsaimtoexemplifytheuseofmodelorganismsandmethodologyin
geneticsandmolecularbiologyresearch.Eachgroupgivesonepresentationononemodel
organism/system.
InFronteryouwillfindfoldersforselectedmodelorganismsinthefolder"ORAL
PRESENTATIONS".Youwillfindanarticletermed"TheArtandDesignofGeneticScreens"ineach
folder.Thisisthemainarticleforthepresentation.Additionalinformationcanalsobefoundin
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theotherarticles.YoucanalsoconsulttheGENOMEarticlesfromWEEK3orWWWlinksposted
withineachorganismfolderorunderLINKS-ModelOrganisms.
Thepresentationswillbeheldinweek7(19.02,09:15–15.00).Youshouldstarttopreparethe
presentationsinweek6.
Belowyouwillfindsomecentralaspectsandasuggestedoutlineofthepresentation.
Scheduledtime:Planfor25minutesincludingquestionsfromtheothergroups.
Oral Presentation Outline
•
Descriptionandhistoryofthemodelorganism.Lifecycle.
•
Genomesizeandorganization.
•
Comparegenometootherorganisms
•
Epigeneticsofyourmodel
•
Whatrecognizesagoodmodelorganism-whatisthescoreforyourorganism?Whyis
yourorganismagoodmodel?
•
Whichtoolsareavailableforgeneticmodifications?Classicalmutagenesis/genetic
engineering?Whichtypesofgeneticmodificationsarepossible(transfection,
transformation,integrationbyhomologousorillegitimaterecombination?)
•
Typesofgeneticscreens(ifyouthinkthatatypeofscreenisaspecialfeatureofyour
organism,presentthisinbrief!)
•
Otherspecialapplicationsand/orpositive/negativefeaturesofthemodel.
•
Specialattention,NobelPrizesetc
•
TheFUTURE...(Applicationsandfutureaspects).
PhD students
PhDstudents(withcoursecodeMBV9120)musthandinanessayonagiventopic.More
informationwillbegivenTuesdayweek4.
Thedeadlineforhandingintheessayis08:00,22.02.2015.
PleaseuploadyouressayinFronterinthefolder"9120Essay".