The measurement problem Measurement theory and provider profiling construct indicator Quality εi(jk) Timothy P. Hofer MD Dept. Medicine, University of Michigan VA Ann Arbor HSR&D Center of Excellence Levels of care Implications of the measurement model Site (clinic, hospital) The indicator is a fallible measure of the construct Provider (physician) Some indicators are less precise than others Quality indicators are very imprecise for a variety of reasons You need to account for the measurement error The location of the construct variability can suggest different causes, interventions and measurement procedures Patient i i i Indicators Intra-class correlation(=reliability) Ability to distinguish between physicians (or sites) single observation under a specified set of conditions of measurement. 2 ⎛ ⎞ σ physician ⎟ Rx = ⎜ 2 2 2 ⎜ ⎟ + + ⎝ σ site σ physician σ patient ⎠ Vol. 281 No. 22, pp. 2065-2160, June 9, 1999 1 Table 3: Amount of variation in hospitalization and outpatient visit rates attributable MD laboratory utilization profiles to a physician practice style effect Adjusted for reliability Unadjusted for reliability Age-Sex Adjusted Casemix Adjusted 13% 10% 7% 4% 0.51 0.40 Unadjusted for reliability (R2) * 8% 8% Reliability adjusted (ICC) † 2% 1% 0.24 0.17 Deviations of MD profiles from mean laboratory utilization ($) Variable Visits % of variation associated w/ physician Unadjusted for reliability(R2) * 60 Reliability adjusted (ICC) † Reliability‡ 20 Hospitalizations % of variation associated w/ physician -20 -60 Reliability‡ Resources available VA Network 11 Diabetes Care Project VA Diabetes Registry Project (1998-2001) Automated Clinical Databases Data warehouse (VA Healthcare and analysis group) Database Components Cohort identification procedure Data quality and measure validation Selected Measures: Resource Use Encounter records (OPC/PTF ) Outpatient Pharmacy Lab primary care provider database (PCMM () Vitals Kerr EA , et al. Journal on Quality Improvement 2002; 28(10):555-65. Selected Measures : Intermediate Outcomes Cost of hypoglycemic medications Cost of home glucose monitoring for patients not on insulin Cost of calcium channel blockers Last A1c value A1c ≥ 9.5% Last LDL value LDL ≥ 3.6 mmol/L (140mg/dl) Quality Outcomes Intermediate Outcomes Processes Quality Outcomes Intermediate Outcomes Processes 2 Selected Measures: Process Measures Selected Measures: Mixed or Linked Measure Hemoglobin A1c obtained LDL-C obtained Lipid profile obtained LDL ≥ 3.6 mmol/L (140mg/dl) or on a statin Quality Outcomes Intermediate Outcomes Processes Are there differences between physicians? Outcomes What are the sources of variation? Diabetes Care Indicator Noise Unmeasured differences Physician effects Noise Clinic or group effects Physician Health System/payor effects Clinic Intermediate outcomes Diabetes Care Indicator Intermediate Outcomes Last HbA1c value Team PCP 1% 0 2% Cost of home glucose monitoring for patients not on insulin 18% 3% 3% Cost of home glucose monitoring for patients on insulin 8% 2% 1% Cost of Calcium Channel Blockers 1% 0 0 Resource Use Cost of hypoglycemic medications System/Payor Level of Care Facility Process measures Level of Care Diabetes Care Indicator Facility Team PCP 12% 0 1% Last HbA1c value ≥ 9.5% 16% 0 0 Last LDL-C value‡ 7% – 1% Last LDL-C value ≥ 3.6 mmol/L (140mg/dL)‡ 2% 1% 1% Last LDL-C value < 3.6 mmol/L (140 mg/dL) or on a statin (%)‡ 2% 2% 5% Process Measures† Hemoglobin A1c (HbA1c) obtained Low Density Lipoprotein Cholesterol (LDL-C) obtained‡ Lipid profile obtained Level of Care Facility Team PCP - 1% 8% – 2% 8% 7% 2% 9% 3 Physician effect size Physician effect size Negligible PCP Effect 200 Last LDL-C Value (1%) Panel size 150 100 Small Moderate Cost of home glucose monitoring for patients not on Insulin Last LDL-C value <3.6 mmol/L or on a statin (5%) Hemoglobin A1c obtained (8%) 50 Median PCP Panel size in study sample 0 .02 .04 .08 .10 Variance attributable to level of care Implicit chart review – site level How many reviews are needed? 1 (to detect differences between sites) Re liability of site level quality score .2 .4 .6 .8 Trained physician reviewers 621 records 26 clinical sites Site level reliability HTN 0.17 DM 0.10 COPD 0.11 Measurement models are fundamentally important to measuring and profiling quality. There is often little reason or capability to profile at the physician level. Profiles that ignore measurement error 0 Conclusions 0 10 20 30 40 50 cases Misrepresent the variability in quality Are difficult (or impossible) to validate Example – the imprecise thermometer Budget cuts inspire innovation in the clinic 4 Observed vs. true temperature 85 85 90 90 Body temperature(F) 95 100 Body temperature(F) 95 100 105 105 Observed temperature true observed Scale transformation 0 85 .2 90 Body temperature(F) 95 100 Probability of prevention .4 .6 .8 105 1 Strength in numbers observed true observed average 1 Reliability 2 3 4 Rating of preventability 5 6 Effect of gaming Outlier Physicians (1991) “A person with two watches is never quite sure” 0.4 Deviations of MD profiles from mean Hgb A1c levels “A person with one watch knows what time it is” 0.2 0.0 These physicians eliminate from their 1992 panels the patients who in 1991 had HgbA1c levels -0.2 in the top 5%. -0.4 Non-outlier Physicians (1991) 0.4 0.2 These physicians have the same patient panels in 1992 as in 1991. 0.0 -0.2 -0.4 1991 1992 5 6