SEATTLE GENETICS
TOUR + MIXER
WELCOME
4:00 – 4:15 p.m. Registration + Networking
4:15 – 4:30 p.m. Opening Remarks
4:30 – 5:30 p.m. Seattle Genetics Building Tours
5:30 – 6:30 p.m. Networking Mixer + ISPE Announcements
APPETIZERS + DRINKS WILL BE PROVIDED AFTER THE TOUR.
SEATTLE GENETICS PROJECT TEAM
OWNER
Seattle Genetics, Inc.
SYSTEMS
 PCS
ARCHITECT
 PSF Mechanical
Stock & Associates
 Auburn Mechanical
STRUCTURAL DESIGN
DESIGN-BUILD MECHANICAL + PLBG
RODI
CONTRACTOR
 Sparling
GLY Construction
 Nelson Electric
ELECTRICAL DESIGN
LIGHTING DESIGN + ELECTRICAL
INSTALLATION
 The Greenbusch Group
COMMISSIONING AGENT
S E AT T L E G E N E T I C S
H I S TO RY
is a biotechnology company focused on developing

Company founded in 1998
and commercializing empowered antibody-based

First building mixed use lab
and office 2001

Second building dedicated
to office 2008

Third building mixed use
lab and office 2011

Total square foot 196,000
therapies for the treatment of cancer. We are
leading the field in developing antibody-drug
conjugates (ADCs), a technology designed to
harness the targeting ability of antibodies to deliver
cell-killing agents directly to cancer cells.
ADCETRIS® was approved by the FDA in 2011 and Health
Canada in 2013 for two indications.
PROJECT APPROACH PHASED DELIVERY
PHASE 1
CORPORATE
OFFICE TI
PHASE 2
LABORATORY
CONSTRUCTION
PHASE 3
LABORATORY +
LARGE MEETING SPACE
CONSTRUCTION
 45,000 SF
 Duration: May 23, 2011 – September 26, 2011 [~5 Months]
 23,000 SF
 Duration: July 23, 2012 – March 5, 2013 [~8 Months]
 15,000 SF
 Duration: March 15, 2013 – October 10, 2013 [~7 Months]
PHASED DELIVERY TOUR AREAS
LEVEL 1
LEVEL 2
SUCCESS STORY PRE-PLANNING
APPROACH
 Master Plan Pre-planning
 Early Preconstruction with City of Bothell
 Leverage Multiple Permit Packages
 Clarify Validation Requirements/Needs
 Equipment Procurement Strategies
 Pull Planning
 3D Model Collaboration + Prefabrication
 Lean Principals
ZONED WORK PLAN | PHASE 2
SUCCESS STORY LESSONS LEARNED
 Lab Equipment Procurement [Sterilizers]
 Mechanical Equipment Coordination + Procurement
 HazMat Prefab Building [Early Procurement]
 Phased Permit Strategies with Coordinated
Procurement Schedule
 Ensure VMP is Developed During Preconstruction
QUESTIONS?
Se at tle genetics | ph ase 2 logistic s
Construction Access from
East Lot (job trailer staging)
NO Construction Access
***Phase 2 Work Area***
21'-1"
GWB
GWB
(through taping,
then finish sub#
5)
Safety Perimeter
Finish Sub #3
8'-11"
***PPE Beyond this Point***
***Lay Down Area***
8'-7"
***NORTH Loading Dock***
10'-0"
21'-1"
(through framing,
then "just-in-time"
deliveries)
Finish Sub #4
WEST Corridor Access
12'-0"
GLY
GLY
PSF
PSF
(through rough-in,
then finish Sub #1)
Nelson
Nelson
(through rough-in,
then finish Sub #2)
Limited Work/Access
to this area
NO WORK - NO
ACCESS in this area
General Notes:
1. NO TABACCO USE on-site
2. Parking is in designated construction parking zones only.
3. Site access is through the man doors at the Northend of the buildings.
4. Visitors must check-in at the GLY Office
5. Coordinate deliveries 48 hours in advance with GLY. Deliveries should go directly
to the building Loading Dock - DO NOT check-in at the building reception desk.
SOUTH Staging Area and LOAD/UNLOAD
EAST Corridor Access
***SOUTH Loading Dock***
Seattle Genetics Storage
~4400 sf
Seattle Genetics - Phase 2 Logistics Plan_REV. 0
GLY Sketch dated 06-14-12
21717 30th Dr. SE, Bothell WA
Se at tle genetics | e x terior logistic s
Con
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rking (19
ction Pa
Constru
stru
ctio
nP
arkin
g (1
Construction Fence
AD
NLO
0)
***
Area
AD/U
H LO
ORT
***N
GLY
Park
ing
ape
(9)
a
Are
dsc
Lan
OW
***N
General Notes:
1. NO TABBACO USE on-site
2. Parking is in designated
construction parking zones only.
3. Site access is through the man
doors at the Northend of the
buildings.
4. Visitors must check-in at the
GLY Office
5. Coordinate deliveries 48 hours
in advance with GLY. Deliveries
should go directly to the building
Loading Dock - DO NOT check-in
at the building reception desk.
Construction
Trailers
MAIN CONSTRUCTION
ENTRANCE
ape
ng
dsc
Lan
agi
r St
Ko
OR
NO Construction Access
through East Doors
low
this
verf
nO
ctio
on
stru
Con
a
Are
Pedestrian "Safety
Path" to Building 1
)
(15
sid
a
Are
tag
1"
ing
1
27'-
***
ing
uild
ape
dsc
Lan
Construction Overflow (8)
I-405
eB
f th
eo
Bothell-Everett Highway
***Location of Boiler
Enclosure/HazMat
Enclosure Work***
XS
NNE
CO
AD
NLO
a***
Are
D/U
A
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)
tagin
low
"
32'-0
HS
OUT
***S
C
verf
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ons
(10
Se at tle genetics | ph ase 2 zones Se at tle genetics | ph ase 1 PH ASE Facts
5 Months
45,000 SF
$115/SF
„„ 27 RFIs | 16 Confirming
„„ Designed to LEED
Certification Standards
„„ Corporate Offices
„„ High Density File Storage
„„ Campus IT Hub
„„ New Elevator, Feature
Stair, Main Lobby,
Entry Canopy
Building 3 – Level 2
„„ Demo/Structural Upgrade
Included Look-Ahead
Phase 2 Work
Building 3 – Level 1
„„ New BMS System
Se at tle geneti cs | ph ase 2 PH ASE Facts
8 Months | 23,000 SF
$76/SF Rooftop Platform + MEP
$274/SF Lab Construction
„„ 30 RFIs | 22 Confirming
„„ 3 Miles Pipe | 312 Plbg Fixtures
„„ 16 Tons Ductwork
„„ 80 Miles Electrical +
Communication Wiring
„„ 5.5 Miles Conduit
„„ 21 Fume Hoods
„„ 19 Bio-Safety Cabinets
„„ 500 Gall Validated RODI System
„„ 1,700 LF 50mm DI Piping
„„ 84 Pre-Fab Spool Pieces + 1,312
Shop Welds
Building 3 – Level 1
„„ 13 Qualified Labs
„„ 4,600 LF Lab Piping
„„ 900 LF Underground Waste +
Vent Plumbing
„„ New 450KW Genset
Se at tle geneti cs | phase 3
PH ASE Facts
7 Months
9,000 SF | $200/SF Laboratory
5,000 SF | $176/SF Meeting
Space/Laboratory
„„ 30 RFIs | 18 Confirming
„„ New Rooftop Mechanical
Platform
„„ 1,000 LF Lab Piping
„„ 3.5 Tons Ductwork
„„ 37 Miles Electrical +
Communication Wiring
Building 3 – Level 1
„„ Working Adjacent/Below
Phase 2 Labs + Corporate
Offices
S E AT T L E G E N E T I C S
Think. Plan. Build.
200 112th Avenue NE, Suite 300 Bellevue, WA 98004-5878
PO Box 6728 Bellevue, WA 98008-0728
p: 425.451.8877 f: 425.453.5680 w: www.gly.com
S E AT T L E G E N E T I C S T O U R
OCTOBER 24, 2013
PROJECT OVERVIEW —
­ PHASING IN A
MASTER PLAN + LEAN PROCESS
Owner/Developer
Seattle Genetics
Architect
Stock + Associates, Inc.
PROJECT OBJECTIVE
Provide appropriate lab and office resources while simultaneously creating
a better working environment for staff and lowering overall costs.
General Contractor
GLY Construction, Inc.
Partners – Design-Build
Structural Design: PCS
Electrical Design: Sparling
MP Design-Build: PSF Mechanical
RODI: Auburn Mechanical
Electrical Installation: Nelson Electric
Commissioning Agent: The Greenbusch Group
PROJECT GOALS
ƒƒ Use phased plan + Lean process to develop design that aligns with
business operations
LEAN
EXPEDITES
EFFICIENCY.
The corridor MEP rack systems were fabricated
Early in the design process, the team
man hours in the corridor, installing piping and
used 3D modeling to identify areas of
conduit to the racks.
in sections and trucked to the site on casters, rolled
into place, lifted to their final elevation and bolted
to the wall. This process eliminated hundreds of
congestion in the lab work spaces and
Underground drainage pipe was fabricated in
minimize them. Modeling coordinated
sections, trucked to site and installed the same
the systems in these areas at a
ƒƒ Collaborate with design team to implement modeling to support
prefabrication through a shared 3D Model [BIM] that is reviewed +
refined as design evolves
level of detail that allowed for offsite
ƒƒ Focus on modularity, flexibility, sustainability, lower energy consumption
and install with maximum efficiency.
day. This strategy minimized the need for lay down
areas and open trench time that would conflict
prefabrication. Then Lean processes
with installation of overhead utilities systems via
helped us plan, build, expedite delivery
overhead lifts.
Our multi-faceted approach allowed
PROJECT APPROACH
Nine phases of sequenced construction of the Master Plan helped Seattle
Genetics grow. Now on the fourth consecutive project, GLY just completed 23,000 square
Surface Mounted Raceway at the lab benches was
unrestricted flow of labor and materials
pre-wired and trimmed-out prior to arriving onsite.
through the corridor and into the labs,
As soon as it was delivered, it was attached to the
while overhead MEP systems were
wall, thus eliminating congestion at the lab benches
feet of validated development and research laboratory space, and nearly 81,000 square feet
being installed in the corridor.
where other trades were trimming-out the plumbing
and electrical systems.
of renovated office and large meeting space, and complex mechanical, electrical, plumbing and
fireproofing installations. Seattle Genetics’ new research lab spaces were on a fast track to
support work on their growing cancer drug development pipeline. The complex work took
careful planning with a project team of trusted partners.
It’s all about flow + timing was crucial. Stock & Associates
Validated = Qualified. The aggressive permitting and multi-zone
plus GLY partnered with subcontractors in a series of Lean Pull Planning
schedule aligned with our Quality Control approach. Throughout
Seattle Genetics, architect Stock & Associates and Design-Build subcontractors PSF Mechanical,
sessions to coordinate sequencing and scope durations into a Phasing
the lab build-out, GLY supported documentation for 11 qualified lab
Nelson Electric and Auburn Mechanical. The team developed a strong collaborative approach to
Plan that maximized schedule efficiency. Laboratories were designed
spaces and worked directly with Seattle Genetics’ Facility Compliance
challenging requirements, that began with Stock completing their design in Revit, which became
around a corridor with all gases and utilities installed in overhead
team and their third party validation agent to ensure a timely, efficient
the foundation for the 3D MEP coordination.
rack systems that fed directly into the lab spaces and down to the lab
transition into newly qualified and validated lab spaces – so research
benches. The most efficient approach was to figure out how to install the
teams could get underway as soon as possible.
Strong collaboration makes it work. Throughout all phases, GLY worked closely with
With the designers working hand-in-hand with the contractor and subcontractors through
actual construction, decisions were made and issues resolved quickly in Phase 2 and Phase 3.
MEP systems in the corridors while concurrently building out lab spaces.
Together, the team accomplished a lab build-out that included 20 adjustable-height Bio-Safety
The highly accurate 3D software model and lean prefabrication strategy
cabinets and 24 fume hoods, supported by all new mechanical and electrical systems, new emergency
provided the solution. This approach jump-started the MEP process,
generator, and a validated RODI pure water generation system and loop that fed the lab areas.
eliminated redundancies, assured accuracy, accelerated schedule and
BOTTOM LINE | DESIGN, SYSTEMS AND INSTALLATIONS
CAME TOGETHER SMOOTHLY, MET END-USER PHASED
START-UP AND OCCUPANCY OF THE NEW LAB SPACES.
05.23
Start
Demo/
Structural
Upgrades
MAY 2011
06.13
GMP Executed
07.01
Start Finishes
09.26
Certificate of
Occupancy
JUN 2011
JUL 2011
SEATTLE GENETICS TOUR | OCTOBER 24, 2013
AUG 2011
SEP 2011
07.23
Demo/
Structural
Upgrades
07.24
CLEAN
BUILD:
Initiate
Level 1
JUL 2012
08.01
ƒƒ Coordination +
Procurement
Long-lead Casework
+ Equipment
ƒƒ Coordinate Logistics
with Validation
10.04
Needs
CLEAN
08.22
BUILD:
07.30
90% CD
Initiate
Start
Model
Level 2
Demo/
Complete
Structural
08.27
Upgrades
Install Plumbing
in Labs
AUG 2012
SEP 2012
11.29
CLEAN
BUILD:
Initiate
Level 3
10.05-10
Start Lab +
Corridor MEPF
Rough-in
10.15
100%
CD Set
Issued
10.31
GMP
Established
11.13
RODI
Rough-in
Begin
MEP
Install
Verifications
Checks
OCT 2012
11.17
Set
Rooftop
Equipment
NOV 2012
12.17
Rooftop Equipment
Start-up
12.18
Lab Equipment +
Casework Install
12.27
Begin
Lab MEP
Trim-out
DEC 2012
JAN 2013
01.28
Start Commissioning
MEP + Lab Equipment
02.04
SeaGen
Begins
Early
Equipment
Validation
Work in
Labs
FEB 2013
03.01
Lab
Commissioning
100% Complete
03.05
Certificate of
Occupancy
MAR 2013
APR 2013
2013 PHASE 3
KEY PROJECT DATES
2012 PHASE 2
2011 PHASE 1
created efficiencies in timing, installation and cost control.
03.15
Begin Demo/
Structural
Upgrades
03.29
Begin
Under
Slab
Plumbing
MAR 2013
APR 2013
04.17
Prep +
Fireproof
Structure
05.14
Start MEPF
Rough-in
06.01
Begin MEP
Install
Verification
Checks
Prior
to Wall +
Ceiling
Cover
07.13
Set
Rooftop
Equipment
06.17
Start
Finishes
MAY 2013
JUN 2013
08.12
ƒƒ Install Lab
Equipment +
Casework
ƒƒ Start-up Rooftop
Equipment
09.13
RODI
Validated
Loop
Tie-in
08.19
Begin Lab
MEP Trim-out
10.07
Commissioning
100% Complete
10.10
Lab
Certificate of
Occupancy
08.26
Begin Lab
Commissioning
JUL 2013
AUG 2013
SEP 2013
OCT 2013
NOV 2013