Slide set 15 Stat402B (Spring 2016) Last update: April 17, 2016 Stat 402 (Spring 2016): Slide set 15 Fractional Factorial Designs • So far we have discussed experiments involving all treatment combinations in 2k factorials (blocked or not). • But the numbers of runs (or experimental units) required for these complete replicates of 2k factorials increases geometrically as k increases. • However, in practice when k is not small, the desired information can often be obtained by performing only a selected fraction of the 2k experimental runs needed for a single replicate of a full factorial. • For simplicity of discussion, consider a 23 factorial in a 1/2 replication, i.e., we will run only 1/2 of the 8 treatment combinations. 1 Stat 402 (Spring 2016): Slide set 15 One-half fraction of a 23 factorial • We shall use the 4 treatment combinations a, b, c, and abc in a CRD. • What are the effects that can be estimated? • We begin by attempting to estimate the effects using the defining contrasts in the usual way. Treatment Combinations a b c abc I + + + + A + + B + + Factorial Effect AB C AC BC + + + + + + + + ABC + + + + 2 Stat 402 (Spring 2016): Slide set 15 One-half fraction of a 23 factorial (Cont’d 1) • If we examine the contrasts of the observations that estimate the effects carefully, it can be observed that the effects A and BC are estimated by the same contrast. That is, d = 1/2[ya − yb − yc + yabc] Â = 1/2[ya − yb − yc + yabc] and BC • This says that these two effects cannot be estimated separately (i.e., they will always have the same value). They are indistinguishable. • We say that the effect A is aliased with effect BC. In other words, this contrast of observations is identified as estimating both A and BC effects. • In addition, it is seen that the effects B and AC, the effects C and AB, and effects I and ABC are all aliased in pairs. 3 Stat 402 (Spring 2016): Slide set 15 One-half fraction of a 23 factorial (Cont’d 2) • We write all this information in the form: I A B C • • • • = = = = ABC BC AC AB The above is called the alias pattern. The alias pattern is the most important idea in fractional factorials. The alias pattern of a design tells us which of the effects can be estimated. To be able to use a fractional factorial the experimenter needs to know in advance whether certain effects can be assumed to be negligible. For example, in the above, if we knew that the two factors B and C do not interact from prior knowledge about these two factors, then the value we estimated by the contrast 1/2(ya − yb − yc + yabc) above should be an estimate of the effect A (instead of BC). 4 Stat 402 (Spring 2016): Slide set 15 One-half fraction of a 23 factorial (Cont’d 3) • In the above example, we selected the treatment combinations to be run in the following way. Take the effect aliased with the mean effect I (in this case ABC), and write the defining contrast for that effect: ABC=1/2[abc+a+b+c-ab-ac-bc-(1)] • • We used the 4 treatment combinations with the + sign in the experiment. This is just one method of obtaining the treatment combinations (or the 1/2 fraction) to be run. We will call this Method I. The relation I=ABC is called the defining relation, and we use it to obtain the alias pattern in the following way: 1. Take the defining relation I=ABC 2. Multiply both sides by A to give A(I) = A2BC which simplifies to A=BC 3. Similarly multiplying by B and C, respectively, gives B=AC and C=AB. • Thus, the defining relation is the key to obtaining the alias pattern. 5 Stat 402 (Spring 2016): Slide set 15 One-half fraction of a 23 factorial (Cont’d 4) • Most applications involve − aliasing main effects with 3-factor or higher order interactions, and − aliasing 2-factor interactions with 3-factor or higher order interactions, etc. • Then, we assume that the 3- and higher order interactions do not exist, in order to estimate main effects and 2 factor interactions. • As discussed above, a method for obtaining the treatment combinations to be run involves writing out the defining contrast for the effect in the defining relation and choosing the treatment combinations with the + signs as the desired fraction. (Method I) • However, this method becomes too unwieldy for large experiments. The following method (Method II) is used in those cases. 6 Stat 402 (Spring 2016): Slide set 15 One-half fraction of a 23 factorial (again) • • Suppose we want to obtain the treatment combinations to be run for a 1/2 fraction of a 23 factorial, as in the previous example. Write the defining contrasts for A and B effects as for a 22 factorial. The generate a contrast for C using C=AB. Thus (1) a b ab • • A + + B + + C(=AB) + + c a b abc Now the treatment combinations to be run are obtained by interpreting the columns as indicating levels of factors A, B, and C to be used. For example, (-,-,+) is c; (+,-,-) is a, etc. Thus the treatment combinations to be run are c, a, b, and abc, as also was obtained usin Method I. 7 Stat 402 (Spring 2016): Slide set 15 • • • • 1 th 2p fraction of a 2 factorial is called a 2k−p fractional In general factorial. For example a 1/2 fraction of a 24 factorial is a 24−1 fractional factorial and has 8 runs. An example, of a 24−1 experiment is given in Example 8.1 (p.326 text). To determine the 8 runs that are chosen to be run in this example, consider the defining relation I=ABCD and use Method I. Write the contrast for ABCD: (1) ABCD=+ • 2k−p Fractional Factorial k a - b - ab + c - ac + bc + abc - d - ad + bd + abd - cd + acd - bcd - abcd + Then select those 16 treatment combinations that has + signs (1), ab, ac, bc, ad, bd, cd, and abcd. 8 Stat 402 (Spring 2016): Slide set 15 4−1 2 with defining relation I=ABCD • Alternatively Method II could be used. Write the defining contrast for A, B, and C as for a 23 factorial and then generate a contrast for D using D=ABC: • Again the treatment combinations to be run are obtained by interpreting the columns as indicating levels of factors A, B, C, and D, as shown in the above table. 9 Stat 402 (Spring 2016): Slide set 15 • 24−1: Analysis Computations in the 1/2 fraction of the Filtration Data Example are shown below. The estimate of effects are obtained by first computing the contrast and then dividing by 2k−p−1. Treatment Combination (1) ad bd ab cd ac bc abcd Contrast Divisor Estimate 45 100 45 65 75 60 80 96 I + + + + + + + + 566 8 70.75 A + + + + 76 4 19 B + + + + 6 4 1.5 Factorial Effects AB C AC + + + + + + + + + + + + -4 56 -74 4 4 4 -1 14 -18.5 BC + + + + 76 4 19 (D=ABC) + + + + 66 4 16.5 10 Stat 402 (Spring 2016): Slide set 15 24−1: Analysis (Cont’d) • The fact that the above are the only factorial effects that need to be computed is clear from looking at the alias pattern: I=ABCD A=BCD AB=CD B=ACD AC=BD C=ABD BC=AD D=ABC • The analysis is based on assuming that the 3 factor and higher order interactions do not occur. From this table it is not unreasonable to conclude that main effects A, C, and D are large and that AC(=BD) and AD(=BC) are also significant. • These facts are summarized in Table 18.4 (p.327 of the text). 11 Stat 402 (Spring 2016): Slide set 15 • Also discussed in the text is how the complimentary half fraction given by I=−ABCD is combined with the above fraction to make more satisfactory conclusions. (See Example 8.3) 12