Saami K. Yazdani, PhD
University of South Alabama
Department of Mechanical Engineering
150 Jaguar Drive, Shelby Hall, Room 3123
Mobile, AL 36688
T: 251.460.7220, F: 251.460.6549, M: 703.966.3047
Email: syazdani@southalabama.edu
EDUCATION
Wake Forest University School of Medicine
Doctorate of Philosophy, Biomedical Engineering
Department of Biomedical Engineering / Wake Forest Institute for Regenerative Medicine
Dissertation: “Bioreactor Preconditioning of Tissue Engineered Blood Vessels”
2008
Winston-Salem, NC
Virginia Tech
Master of Science, Engineering Mechanics
Department of Engineering Science and Mechanics
Thesis: “Geometry Induced Flow Disturbances”
2004
Blacksburg, VA
Virginia Tech
Bachelor of Science, Engineering of Science and Mechanics
Department of Engineering Science and Mechanics
2001
Blacksburg, VA
EXPERIENCE
Assistant Professor
University of South Alabama, Department of Mechanical Engineering
August 2012 - present
Mobile, AL
Post-Doctoral Research Scientist
2008-2012
CVPath Institute, Inc.
Gaithersburg, MD
• Conducted pathologic assessments of catheter-based clinical devices for the purpose of understanding mode
of failures related to design and implementation
• Developed in vitro models to analyze the biological impact of varying design criteria of coronary stents
• Performed histological and molecular assessments of vulnerable lesions in post-mortem material to better
understand events leading to sudden cardiac death
• Initiated collaboration with NIH and FDA which has lead to multiple research projects and publications
submissions
• Served as project manager for multiple contract-based preclinical studies.
• Assisted in budget planning for future work load projections
Graduate Research Assistant
2003-2008
Wake Forest University, Department of Biomedical Engineering
Winston-Salem, NC
Wake Forest Institute for Regenerative Medicine (WFIRM)
• Designed, built and successfully implemented a novel blood vessel bioreactor
• Successfully developed dual seeded tissue engineered blood vessels (TEBV) ; the first step to toward an
alternate solution for synthetic grafts used for dialysis patients
• Computed Finite Element Analysis of stented arteries
• Developed a novel in vitro system for evaluation of stent-induced cell proliferation
Graduate Teaching Assistant
Summer 2003
Virginia Tech, The Center for the Enhancement for Engineering Diversity
Blacksburg, VA
advisor: Tremayne Waller
• Taught freshmen engineering students fundamental concepts in mathematics and physics through interactive
learning
Saami K. Yazdani, PhD
Graduate Research Assistant
Virginia Tech, Department of Engineering Science and Mechanics
advisor: Pavlos Vlachos, PhD
• Performed analysis on fluid dynamics of arterial flow in control animals
• Tested and quantified stent-induced flow disturbances
Peer Reviewed Journal Articles
2001-2003
Blacksburg, VA
PUBLICATIONS
1. Otsuka F, Cheng Q, Yahagi K, Acampado E, Sheehy A, Yazdani SK, Sakakura K, Euller K, Perkins LE, Kolodgie FD,
Virmani R, Joner M. Acute Thrombogenicity of a Durable Polymer Everolimus-Eluting Stent Relative to Contemporary
Drug-Eluting Stents With Biodegradable Polymer Coatings Assessed Ex Vivo in a Swine Shunt Model. JACC
Cardiovasc Interv. 2015;8(9):1248-60.
2. Malve M, Gharib AM, Yazdani SK, Finet G, Martinez MA, Pettigrew R, Ohayon J. Tortuosity of coronary bifurcation
as a potential local risk factor for atherosclerosis: CFD steady state study based on in vivo dynamic CT
measurements. Ann Biomed Eng. 2015; 43(1):82-93.
3. Yazdani SK, Pacheco E, Nakano M, Otsuka F, Naisbitt S, Kolodgie FD, Ladich E, Rousselle S, Virmani R. Vascular,
downstream, and pharmacokinetic responses to treatment with a low dose drug-coated balloon in a swine femoral
artery model. Catheter Cardiovasc Interv. 2014; 83(1):132-140.
4. Bouvier A, Deleaval F, Doyley MM, Yazdani SK, Finet G, Le Floc'h S, Cloutier G, Pettigrew RI, Ohayon J. A direct
vulnerable atherosclerotic plaque elasticity reconstruction method based on an original material-finite element
formulation: theoretical framework. Phys Med Biol. 2013; 58(23):8457-8476.
5. Yazdani SK, Nakano M, Otsuka F, Kolodgie FD, Virmani R. Animal models of vascular repair and reendothelialization. Rev Esp Cardiol Supl. 2013; 13(E):20-28.
6. Yazdani SK, Sheehy A, Nakano M, Nakazawa G, Vorphal M, Outsuka F, Donn RS, Perkins LE, Simonton CA, Kolodgie
FD, Virmani R. Preclinical evaluation of 2nd generation everolimus and zotarolimus eluting coronary stents. Journal
of Invasive Cardiology. 2013; 25 (8):383-90.
7. Deleaval F, Bouvier A, Finet G, Cloutier G, Yazdani SK, Le Floc'h S, Clarysse P, Pettigrew RI, Ohayon J. The
Intravascular Ultrasound Elasticity-Palpography Technique Revisited: A reliable Tool for the in vivo Detection of
Vulnerable Coronary Atherosclerotic Plaques. Ultrasound in Medicine & Biology. 2013; 39(8):1469-81.
8. Yazdani SK, Otsuka F, Nakano M, Ladich E, Virmani R. Pathology of Saphenous Vein Grafts. Interventional
Cardiology Clinics. 2013; 2(2):242-249.
9. Habib A, Karmali V, Polavarapu R, Akahori H, Nakano M, Yazdani S, Otsuka F, Pachura K, Davis T, Narula J, Kolodgie
FD, Virmani R, Finn AV. Metformin impairs vascular endothelial recovery after stent placement in the setting of local
eluted mammalian target of rapamycin inhibitors via s6 kinase-dependent inhibition of cell proliferation. JACC.
2013; 61 (9):971-80.
10. Le Floc'h S, Cloutier G, Saijo Y, Finet G, Yazdani SK, Deleaval F, Rioufol G, Pettigrew RI, Ohayon J. A Four-Criterion
Selection Procedure for Atherosclerotic Plaque Elasticity Reconstruction Based on In Vivo Coronary Intravascular
Ultrasound Radial Strain Sequences. Ultrasound in Medicine & Biology. 2012; 38(12):2084-2097.
11. Tillman BW, Yazdani SK, Neff LP, Corriere MA, Christ GJ, Soker S, Geary RL, Yoo JJ. Bioengineered Vascular Access
Maintains Structural Integrity in Response to Arteriovenous Graft Flow and Repeated Needle Puncture. Journal of
Vascular Surgery. 2012; 56(3):783-93.
12. Yazdani SK, Farb A, Nakano M, Vorpahl M, Ladich E, Finn AV, Kolodgie FD, Virmani R. Pathology of drug-eluting
versus bare metal stents in saphenous vein graft lesions. JACC Cardiovascular Intervention. 2012; 5(6):666-74.
13. Otsuka F, Finn AV, Yazdani SK, Nakano M, Kolodgie FD, Virmani R. The Importance of the Endothelium in
Atherothrombosis and Coronary Stenting . Nature Reviews Cardiology. 2012; 9(8): 439-53.
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14. Yazdani SK, Nakano M, Otsuka F, Kolodgie FD, Virmani R. Accelerating Endothelialization of Coronary Stents by
Capturing Circulating Endothelial Progenitor Cells with CD34 antibody. Interventional Cardiology. 2012;4(2): 168181.
15. Yazdani SK, Kolodgie FD, Virmani R. Ex vivo and preclinical assessment of an endothelial progenitor cell capturing
bioengineering stent. Minerva Cardioangiologica. 2012; 60(1):11-22.
16. Nakano M, Vorpahl M, Otsuka F, Taniwaki M, Yazdani SK, Finn AV, Ladich ER, Kolodgie FD, Virmani R. Ex vivo
assessment of vascular response to coronary stents by optical frequency domain imaging. JACC Cardiovascular
Imaging. 2012; 5(1):71-82.
17. Finn AV, Nakano M, Polavarapu R, Karmali V, Zhao X, Yazdani S, Davis T, Habib A, Saeed O, Narula J, Kolodgie FD,
Virmani R. Hemoglobin directs macrophage differentiation and determines lipid uptake in human atherosclerotic
plaques. Journal of American College of Cardiology. 2012; 59(2):166-77.
18. Larsen K, Cheng C, Tempel D, Parker S, Yazdani S, den Dekker WK, Houtgraaf JH, de Jong R, Hoor SS, Ligtenberg E,
Kolodgie FD, Serruys PW, Virmani R, Duckers HJ. Capture of circulatory endothelial progenitor cells and accelerated
re-endothelialization of a bioengineered stent in human ex vivo shunt and rabbit denudation model. European
Heart Journal. 2012; 33(1):120-8.
19. Otsuka F, Nakano M, Yazdani SK, Ladich E, Kolodgie F, Virmani R. Pathology of fist-generation drug eluting stents.
Interventional Cardiology. 2011; 6(1):28-35.
20. Yazdani SK, Vorpahl M, Nakano M, Shih-Horng S, Kolodgie FD, Virmani R. In vitro and in vivo characterization of
biodegradable polymer-based drug eluting stent. Euro Intervention. 2011; 7(7):835-43.
21. Sheehy A, Hsu S, Sinn I, Tai J, Kolodgie FD, Nakazawa G, Yazdani SK, Quee SC, Virmani R, Polyakov I. Vascular
response to coronary artery stenting in mature and juvenile swine. Cardiovascular Revascularization Medicine.
2011; 12(6):375-84.
22. Ohayon J, Gharib AM, Garcia A, Heroux J, Yazdani SK, Valve M, Tracqui P, Martinez MA, Doblare M, Finet G,
Pettigrew RI. Is Arterial Wall-Strain Stiffening an Additional Process Responsible for Atherosclerosis in Coronary
Bifurcations: in vivo Study Based on Dynamic CT and MRI. American Journal of Physiology – Heart and Circulatory
Physiology. 2011; 301(3): H1097-107.
23. Nakazawa G, Otsuka F, Nakano M, Vorpahl M, Yazdani SK, Ladich E, Kolodgie FD, Finn AV, Virmani R. The pathology
of neoatherosclerosis in human coronary implants: bare metal and drug-eluting stents. Journal of the American
College of Cardiology. 2011; 57(11), 1314-1322.
24. Neff LP, Tillman BW, Yazdani SK, Machingal M, Yoo JJ, Soker S, Bernish B, Geary RL, Christ GJ. Vascular smooth
muscle enhances functionality of tissue engineered blood vessels in vivo. Journal of Vascular Surgery. 2011; 53(2),
426-434.
25. Yazdani SK, Nakano M, Otsuka F, Kolodgie FD, Virmani R. Atheroma and coronary bifurcations: before and after
stenting. EuroIntervention. 2010; 6, J24-30.
26. Vorpahl M, Yazdani SK, Nakano M, Ladich E, Kolodgie FD, Finn AV, Virmani R. Pathobiology of stent thrombosis
after drug-eluting stent implantation. Current Pharmaceutical Design. 2010; 16(36), 4064-4071.
27. Reifart N, Gyongyosi M, Hauptmann KE, Rabe A, Enayat D, Giokoglu K, Kolodgie FD, Vorpahl M, Yazdani SK,
Hemetsberger R, Samaha E, Pavo IJ, Virmani R. Pre-clinical and clinical study results for the CoractoTM Rapamycineluting stent – A new-generation drug-eluting stent. Interventional Cardiology. 2010; 5, 39-42.
28. Yazdani SK, Vorpahl M, Ladich E, Virmani R. Pathology and vulnerability of atherosclerotic plaque: Identification,
treatment options, and individual patient differences for prevention of stroke. Current Treatment Options in
Cardiovascular Medicine. 2010; 12, 297-314.
29. Nakazawa G, Yazdani SK, Finn AV, Kolodgie FD, Virmani R. Pathological findings at bifurcation lesions: The impact of
flow distribution on atherosclerosis and arterial healing following stent implantation. Journal of the American
College of Cardiology. 2010; 55, 1679-1687.
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30. Bekkers S, Yazdani SK, Virmani R, Waltenberger J. Microvascular obstruction: Underlying pathophysiology and
clinical diagnosis. Journal of the American College of Cardiology. 2010; 55, 1649-1660.
31. Yazdani SK, Tillman BW, Berry JL, Soker S, Geary RL. The fate of an endothelium layer after preconditioning: An in
vitro and in vivo analysis. Journal of Vascular Surgery. 2010; 51, 174-183.
32. Yazdani SK, Watts B, Machingal M, Jarajapu Y, Van Dyke ME, Christ GJ. Smooth muscle cell seeding of decellularized
scaffolds: The importance of bioreactor preconditioning to development of a more native architecture for tissue
engineered blood vessels. Tissue Engineering Part A. 2009; 15, 827-840.
33. Tillman BW, Yazdani SK, Corriere M, Geary RL, Atala A, Yoo JJ. Efficient recovery of endothelial progenitors for
clinical translation. Tissue Engineering Part C. 2009; 15, 213-221.
34. Yazdani SK, Berry JL. The development of an in vitro system to assess stent induced smooth muscle cell
proliferation: a feasibility study. Journal of Vascular Interventional Radiology. 2009; 20, 101-106.
35. Tillman BW, Yazdani SK, Lee SJ, Geary RL, Atala A, Yoo JJ. The in vivo stability of electrospun polycaprolactonecollagen scaffolds in vascular reconstruction. Biomaterials. 2009; 30, 583-588.
36. Whitlow CT, Geer CP, Mattern CW, Mussat-Whitlow BJ, Yazdani SK, Berry JL, Lalli JH, Claus RO, Challa VR, Morris PP.
Endovascular histologic effects of ultrathin gold-or vitronectin-coated platinum aneurysm coils in a rodent arterial
occlusion model: a preliminary investigation. American Journal of Neuroradiology. 2009; 30, 85-90.
37. Whitlow CT, Yazdani SK, Reedy ML, Kaminsky SE, Berry JL, Morris PP. Investigating sacroplasty: Technical
considerations and biomechanical properties of polymethylmethacrylate infusion into cadaveric sacrum. American
Journal of Neuroradiology. 2007; 28, 1036-1041.
38. Amiel G, Komura M, Shapira O, Yoo J, Yazdani S, Berry JL, Kaushal S, Bischoff J, Atala A, Soker S. Engineering of
Blood Vessels from Acellular Collagen Matrices Coated with Human Endothelial Cells. Tissue Engineering. 2006; 12,
2355-2365.
39. Yazdani SK, Berry JL, Moore J, Vlachos PP. DPIV Measurements of Flow Disturbances in Stented Artery Models:
Importance of Compliance Mismatch. Journal of Biomechanical Engineering. 2004; 126, 559-566.
Invited Commentaries and Articles
1. Nakano M, Yazdani SK, Virmani R. The Present State of Drug-Coated Balloons. Cardiology Today Intervention.
December 2012.
2. Yazdani SK, Otsuka F, Nakano M, Finn AV, Virmani R. Do animal models of vein graft atherosclerosis predict
outcomes in man? Atherosclerosis. 2012; 223(1): 102-5.
3. Yazdani SK, Kolodgie FD, Virmani R. Atherosclerotic Disease at Coronary Bifurcations and the Impact of Stenting.
International Atherosclerosis Society. April 2011.
Book Chapters
1. Nakano M, Kolodgie FD, Otsuka F, Yazdani SK, Ladich ER, Carter-Monroe N, Finn AV, Virmani R. Vulnerable Plaque.
Coronary Heart Disease: Clinical, Pathological, Imaging and Molecular Profiles. Springer, New York, NY, 2012.
2. Machingal MA, Yazdani SK, Christ GJ. Engineering of Large Diameter Vessels. Principles of Regenerative Medicine.
Second Edition. Elsevier, Burlington, MA, 2011.
3. Yazdani SK, Ladich E, Virmani R. Pathology of Myocardial Ischemia, Infarction, Reperfusion, and Sudden Death.
Hurst’s The Heart, 13th Edition. McGraw-Hill, New York, NY, 2011.
4. Nakano M, Vorpahl M, Yazdani S, Ladich E, Kuts R, Kolodgie FD, Finn AV, Virmani R. The Thrombotic AMI Lesion:
Lessons from Pathology. Textbook of STEMI Interventions, 2nd Edition. HMP Communications. Malvern, PA, 2010.
5. Carter-Monroe N, Yazdani SK, Ladich E, Kolodgie FD, Virmani R. Introduction to the Pathology of Carotid
Atherosclerosis: Histologic Classification and Imaging Correlation. In Atherosclerosis Disease Management .
Atherosclerosis disease. Springer, New York, NY, 2010.
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6. Nakano M, Vorpahl M, Yazdani S, Kolodgie FD, Finn AV, Virmani R. Structure of Stable and Vulnerable
Atheromatous Plaques. Coronary Stenosis: Imaging, Structure and Physiology. Europa Edition, Toulouse, France,
2010.
7. Yazdani SK, Christ GJ. Engineering of Large Diameter Vessels. Principles of Regenerative Medicine. Elsevier,
Burlington, MA, 2008.
Abstracts and Conference Papers
1. Turner E, Marzieh A, Yazdani SK. Pharmacokinetic Evaluation of Non-Stent Drug Delivery: An In Vitro System For
Rapid Evaluation, NCVH 2015, May 27 - 29, New Orleans, LA.
2. Turner E, Marzieh A, Christians U, Yazdani SK. Ex vivo system for pharmacokinetic analysis of catheter-based,
vascular drug delivery. 31st Annual Southern Biomedical Engineering Conference, 2015, May 1-2, New Orleans, LA.
3. Carroll N, Morrison J, Gould E, Kim SH, Yazdani SK. Efficacy of a Real-Time Optical Measurement System. 31st
Annual Southern Biomedical Engineering Conference, 2015, May 1-2, New Orleans, LA.
4. Turner E, Tomblyn S, Burnett L, Yazdani SK. Keratose as a novel drug carrier for drug coated balloons. Society for
Biomaterials Annual Meeting, 2015, April 15-18, Charlotte, NC. b
5. Moore G, Yazdani SK. An in vitro model of endothelialized scaffolds to assess the impact of varying stiffness. Annual
Biomedical Research Conference for Minority Students, 2014, November 11-14, San Antonio, TX.
6. Atigh M, Yazdani SK. Pharmacokinetic Evaluation of Non-Stent Drug Delivery: An In Vitro System For Rapid
Evaluation. BMES Annual Meeting, 2014, October 22-25, San Antonio, TX.
7. Yazdani SK, Atigh M, Kim SH, Finet J, Pettigrew RI, Ohayon J. An original endothelialized coronary bifurcation model
to investigate pathologic mechanisms underlying coronary atherosclerotic disease. 7th World Congress of
Biomechanics, 2014, July 6-11, Boston, MA.
8. Huot A, Yazdani SK. Finite element analysis of arterial vessel wall stiffness. 30th Annual Southern Biomedical
Engineering Conference, 2014, April 11-12, Gulfport, MS. (Journal of the Mississippi Academy of Sciences. 2014; 59
(Supl.), 347-350)
9. Turner E, Tomblyn S, Burnett L, Yazdani SK. Keratin as a novel drug carrier for drug coated balloons. 30th Annual
Southern Biomedical Engineering Conference, 2014, April 11-12, Gulfport, MS. (Journal of the Mississippi Academy
of Sciences. 2014; 59 (Supl.), 204-208)
10. Parks A, Yazdani SK. Development of silicone coronary bifurcation models for in vitro flow evaluation. 30th Annual
Southern Biomedical Engineering Conference, 2014, April 11-12, Gulfport, MS. (Journal of the Mississippi Academy
of Sciences. 2014; 59 (Supl.), 383-386)
11. Gould E, Carroll N, Jefferson GD, Yazdani SK. Development of a three-dimensional digital image correlation for
displacement and strain measurement of seeded endothelial cells. 30th Annual Southern Biomedical Engineering
Conference, 2014, April 11-12, Gulfport, MS. (Journal of the Mississippi Academy of Sciences. 2014; 59 (Supl.), 379382)
12. Carroll N, Yazdani SK. Development of a novel bench-top model to mimic the lower extremity arteries and stent
mechanics. 30th Annual Southern Biomedical Engineering Conference, 2014, April 11-12, Gulfport, MS. (Journal of
the Mississippi Academy of Sciences. 2014; 59 (Supl.), 332-334)
13. Atigh MK, Smith K, Yazdani SK. Endothelialized in vitro tubular silicone scaffolds. 30th Annual Southern Biomedical
Engineering Conference, 2014, April 11-12, Gulfport, MS. (Journal of the Mississippi Academy of Sciences. 2014; 59
(Supl.), 174-177)
14. Marzieh A, Yazdani SK. Development of an in vitro system for rapid evaluation of cardiovascular devices, NCVH
2013, June 5 - 7, New Orleans, LA.
15. Sojitra P, Yazdani S, Otsuka F, Doshi M, Kolodgie F, Virmani R. A Novel Nano Particle Sirolimus Delivery Via Coated
Balloon. Cardiovascular Research Technologies, 2013, February 23-26, Washington, DC.
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16. Yazdani SK, Kolodgie FD, Virmani R, "Vascular Response to Treatment with a Paclitaxel Coated Balloon in a
Preclinical Femoral Artery Model", BMES 2012 Annual Meeting, October 24-27, Atlanta, GA.
17. Sheehy A, Yazdani S, Berger E, Donn RS, Ngo TD, Pacetti S, Hossainy S, Kolodgie FD, Virmani R, “Pharmacokinetic
Evaluation of Drug Eluting Stents in a Healthy and Atheroclerotic Rabbit Iliac Model”, Transcatheter Cardiovascular
Therapeutics, 2011, November 7-11, San Francisco, CA. (Journal of the American College of Cardiology.
2011;58;B124-B125)
18. Yazdani SK, Nakano M, Sherdiwala DP, Doshi M, Sojitra PN, Kolodgie FD, Virmani R, “A Temporal Assessment of Drug
Distribution Following Local Balloon Delivery of Nanoparticle Sirolimus”, Transcatheter Cardiovascular Therapeutics,
2011, November 7-11, San Francisco, CA. (Journal of the American College of Cardiology. 2011;58;B56)
19. Sheehy A, Yazdani S, Berger E, Donn RS, Ngo TD, Pacetti S, Hossainy S, Kolodgie FD, Virmani R, “Evaluation of Drug
Tissue Concentration Following Stenting in a Healthy Rabbit Iliac Model”, Transcatheter Cardiovascular Therapeutics,
2011, November 7-11, San Francisco, CA. (Journal of the American College of Cardiology. 2011;58;B124)
20. Yazdani SK, Su S, Shulze J, Kolodgie FD, Virmani R, “Endothelialization of Polymer-Free Drug-Coated Stents”, Euro
PCR, 2011, May 17-20, Paris, France. (EuroIntervention. 2011; Vol. 7, Suppl M)
21. Yazdani SK, Parker S, Rowland S, Ligtenberg E, Kolodgie FD, Virmani R, “Anti-CD34 Stent Surface Modification
Reduce Thrombogenicity and Increase Endothelialization”, Euro PCR, 2011, May 17-20, Paris, France.
(EuroIntervention. 2011; Vol. 7, Suppl M)
22. Yazdani SK, Pacheco E, Monroe NC, Kolodgie FD, Virmani R, “A Novel Polymer Coating for Drug Eluting Stent
Applications”, American College of Cardiology & i2 Summit, 2011, April 2-5, New Orleans, LA. (Journal of the
American College of Cardiology. 2011; 5:E1664)
23. Otsuka F, Nakano M, Yazdani SK, Ladich E, Kolodgie FD, Finn AV, Virmani R, “Are Stent Related and Non-Stent
Related Deaths Different Between Drug-Eluting Stents and Bare Metal Stents? A Pathologic Study”, American
College of Cardiology & i2 Summit, 2011, April 2-5, New Orleans, LA. (Journal of the American College of Cardiology.
2011; 57:E1647)
24. Nakano M, Otsuka F, Yazdani SK, Finn AV, Kolodgie FD, Jagat N, Virmani R, “Histomorphometric Characteristics of
High-Risk Plaques”, American College of Cardiology & i2 Summit, 2011, April 2-5, New Orleans, LA. (Journal of the
American College of Cardiology. 2011; 57:E1445)
25. Yazdani SK, Parker S, Rowland S, Ligtenberg E, Larsen K, Houtgraaf J, Serruys P, Duckers HJ, Kolodgie FD, Virmani R,
“The Impact of an Anti-CD34 Stent Surface Modification on the Acute Attachment of Circulating Blood Cells in an
Human Shunt Model’, American Heart Association, 2010, Nov 13-17, Chicago, IL. (Circulation. 2010;122:A20012)
26. Nakano M, Vorpahl M, Yazdani SK, Otsuka F, Kolodgie FD, Virmani R, “OFDI is a Better Predictor of Above Strut
Coverage than IVUS in Stented Human Coronary Arteries Studied Ex-Vivo”, American Heart Association, 2010, Nov
13-17, Chicago, IL. (Circulation. 2010;122:A18936)
27. Yazdani SK, Vorpahl M, Su S, Shulze J, Kolodgie FD, Virmani R, “In Vitro and In Vivo Characterization of
Biodegradable Polymer-Based Drug Eluting Stent”, BMES Annual Fall Scientific Meeting, 2010, October 6-9, 2010,
Austin, TX.
28. Yazdani SK, Kolodgie FD, Virmani R, “Drug Release Kinetics of Coronary Stents: An In Vivo Analysis”, BMES Annual
Fall Scientific Meeting, 2010, October 6-9, 2010, Austin, TX.
29. Yazdani SK, Grant G, Su S, Shulze J, Kolodgie FD, Virmani R, “Endothelialization of Drug-Eluting Stents with
Biodegradable Polymer Coating”, Transcatheter Cardiovascular Therapeutics, 2010, September 21-25, Washington,
DC. (Journal of the American College of Cardiology. 2010;56;B57)
30. Yazdani SK, Kolodgie FD, Virmani R, “Pathology of Drug-Eluting Stents in Saphenous Vein Graft Lesions”, American
College of Cardiology & i2 Summit, 2010, March 14-16, 2010, Atlanta, GA. (Journal of the American College of
Cardiology. 2010;55;10A)
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31. Yazdani SK, Grant G, Su S, Shulze J, Kolodgie FD, Virmani R, “Evaluation of Downstream Myocardial Pathological
Changes After Implantation of BA9-Eluting, PLA-Polymer Abluminally-Coated Stents in a Porcine Coronary Artery
Model”, Transcatheter Cardiovascular Therapeutics, 2009, September 21-25, San Francisco, CA.
32. Yazdani SK, Nakazawa G, Kolodgie FD, Virmani R, “In vitro Assessment of Coronary Stent Re-Endothelialization”,
BMES Annual Fall Scientific Meeting, 2009, October 7-10, Pittsburg, PA.
33. Cheng Y, Sherman W, Yi G, Canditt G, Sheehy A, Tellez A, Gu A, Kolodgie FD, Bradley D, Yazdani SK, Basu S, Schuster
M, Itescu S, Kaluza GL, Virmani R, Granada J, “Catheter-Based Endomyocardial Delivery of Mesenchymal Precursor
Cells Dose Dependently Enhances Myocardial Neovascularization in an Ovine Model of Ischemic Cardiomyopathy’,
Transcatheter Cardiovascular Therapeutics, 2009, September 21-25, San Francisco, CA.
34. Yazdani SK, Nakazawa G, Kolodgie FD, Virmani R, “Pathological Finding in Bifurcation Lesion and Stenting”, 4th
International Symposium on Biomechanics in Vascular Biology and Cardiovascular Disease, 2009, April 16-17,
Rotterdam, Netherlands.
35. Kolodgie FD, Nakazawa A, Yazdani SK, Pacheco E, Xu X, Cheng Q, Ladich E, Virmani R, “Infiltrating CD4 Positive T cells
may Support an Angiogenic Switch in Human Coronary Atheroma”, American Heart Association, 2008, Nov 8-12,
New Orleans, LA. (Circulation. 2008;118:S308-309)
36. Whitlow CT, Berry JL, Geer C, Mattern CW, Yazdani SK, Morris P, “ Endovascular Histological Effects of Ultra-Thin
Gold Coated Platinum Coil in a Rodent Model of Saccular Aneurysm: A Preliminary Investigation”, Radiological
Society of North America, 2008, Nov 30-Dec 5, Chicago, IL.
37. Tillman BW, Yazdani S, Atala A, Yoo JJ, Geary RL, “Tissue Engineering of Vascular Access: A Feasibility Study”,
Southern Association for Vascular Surgery 32nd Annual Meeting, 2008, January 16-19, Naples, FL
38. Yazdani SK, Tillman BW, Soker S, Geary RL, Yoo JJ, Berry JL, Atala A, “Tissue Engineering Blood Vessels for
Hemodialysis Access”, Charlotte Biotechnology Conference, 2007, October 12, Charlotte, NC.
39. Yazdani SK, Watts B, Machingal M, Jarajapu Y, Van Dyke ME, Christ GJ, “Surface Modification and Bioreactor
Protocols for Seeding for Seeding of Engineered Blood Vessel”, NC Tissue Engineering and Regenerative Medicine
Conference, 2007, September 20-21, Winston-Salem, NC.
40. Yazdani SK, Watts B, Machingal M, Jarajapu Y, Van Dyke ME, Christ GJ, “Development of Tissue Engineered Blood
Vessels with a Functional Medial Muscle Layer”, Conference and Exhibition on Tissue Engineering and Regenerative
Medicine (Europe), 2007, September 4 - 7, London, England.
41. Yazdani SK, Watts B, Machingal M, Jarajapu Y, Van Dyke ME, Christ GJ, “Bioreactor Protocols for Improved Cellular
Penetration of Decellularized Scaffolds”, Conference and Exhibition on Tissue Engineering and Regenerative
Medicine (Europe), 2007, September 4 - 7, London, England.
42. Yazdani SK, Berry JL, “Stent Induced Smooth Muscle Cell Proliferation: An In Vitro System for Rapid Evaluation”,
ASME Summer Bioengineering Conference, 2007, June 20-24, Keystone, CO.
43. Yazdani SK, Watts B, Machingal M, Jarajapu Y, Van Dyke ME, Christ GJ, “Cellular Environment and Bioreactor
Protocol for Improved Vascular Smooth Muscle Cell Proliferation of Naturally Derived Scaffolds used in Tissue
Engineered Blood Vessel”, Conference and Exhibition on Tissue Engineering and Regenerative Medicine (North
America), 2007, June 13 - 16, Toronto, Canada.
44. Yazdani SK, Watts B, Machingal M, Jarajapu Y, Van Dyke ME, Christ GJ, “Surface Modification and Bioreactor
Protocols for Seeding Vascular Smooth Muscle Cells onto Decellularized Scaffolds used for Tissue Engineered Blood
Vessel”, Conference and Exhibition on Tissue Engineering and Regenerative Medicine (North America), 2007, June
13 - 16, Toronto, Canada.
45. Yazdani SK, Watts B, Machingal M, Jarajapu Y, Van Dyke ME, Christ GJ, “Smooth Muscle Seeded Natural Collagen
Scaffolds for Tissue Engineered Blood Vessels”, Experimental Biology Annual Meeting, 2007, April 28 – May 2,
Washington, DC.
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Saami K. Yazdani, PhD
46. Yazdani SK, Watts B, Machingal M, Jarajapu Y, Van Dyke ME, Christ GJ, “Development of Naturally Derived
Biomaterial Scaffold For Tissue Engineered Blood Vessels”, Society for Biomaterials Annual Meeting, 2007, April 18 –
21, Chicago, IL.
47. Yazdani SK, Berry JL, “Stent Induced Smooth Muscle Cell Proliferation: An In Vitro System for Rapid Evaluation”,
International Symposium on Endovascular Therapy, 2007, January 28 – February 1, Ft. Lauderdale, FL.
48. Yazdani SK, Machingal M, Jarajapu Y, Van Dyke ME, Christ GJ, “Smooth Muscle Cell Seeding of Decellularized
Scaffolds: Developments towards a Functional Tissue Engineered Blood Vessel”, Wake Forest University Resident’s
and Fellows Research Day, 2006, November 2, Winston-Salem, NC.
49. Yazdani SK, Berry JL, Atala A, Soker S, “Natural Collagen Scaffolds for Tissue Engineered Blood Vessels”,
Experimental Biology Annual Meeting, 2006, April 1 -5, San Francisco, CA.
50. Yazdani SK, Berry JL, Atala A, Soker S, “Natural Collagen Scaffolds for Blood Vessel Engineering”, Society for
Biomaterials Annual Meeting, 2006, April 26-29, Pittsburgh, PA.
51. Yazdani SK, Komura M, Berry JL, Atala A, Soker S, “Endothelialization of Acellular Porcine Scaffolds,” North Carolina
Tissue Engineering Interest Meeting, 2005, October 14, Research Triangle Park, NC.
52. Yazdani SK, Komura M, Berry JL, Soker S, “Characterization of an Endothelialized Tissue Engineered
Small-Caliber Blood Vessel”, Regenerate 2005, March, Atlanta, GA.
53. Yazdani SK, Berry JL, “Investigation of Strut Thickness in Coronary Stents via Finite Element Analysis,” Proceedings of
the ASME IMECE Annual Meeting, November 14-19, 2004, Anaheim, CA.
54. Hantgan RR, Stahle MC, Yazdani SK, Connor JC, Lyles DS, Horita DA, Rocco M, Nagaswami C, Weisel JW, McLane MA,
“Integrin Activation and Clustering Mechanisms Elucidated with Echistatin, A Model Multisite Ligand,” American
Heart Scientific Sessions, November 7-10, 2004, New Orleans, LA.
55. Whitlow CT, Eberhardt AW, Yazdani SK, Reedy ML, Berry JL, Morris PP, “Fluoroscopy-guided Percutaneous Injection
of Polymethylmethacrylate into Cadaveric Hip: A Possible Prophylactic Treatment for Individuals at Risk for Hip
Fracture”, Radiology society of North America Annual Meeting, 2004, October 28 - November 3, Chicago, IL.
56. Yazdani SK, Berry JL, “Vessel Wall Stress Created by Thin Strut versus Thick Strut Stents”, Transcatheter
Cardiovascular Therapeutics, 2004, October, Washington, DC.
57. Yazdani SK, Stahle MC, Guthold M, Berry JL, Hantgan RR, “Platelet Affinity for Coated Stent Surfaces,” BMES Fall
Annual Meeting, October 13-16, 2004, Philadelphia, PA.
58. Charonko J, Yazdani SK, Berry JL, Vlachos PP, “An In-Vitro Comparison of Flow Variations with Stent Design Using
DPIV,” BMES Fall Annual Meeting, October 13-16, 2004, Philadelphia, PA.
59. Charonko J, Yazdani SK, Berry JL, Vlachos PP, “In-Vitro Examination of Coronary flow in Stented Arteries using DPIV,”
BMES Fall Annual Meeting, October 13-16, 2004, Philadelphia, PA.
60. Hantgan RR, Yazdani SK, Stahle MC, Horita DA, Rocco M, “Jump-Starting Fibrinogen: Integrin interactions,” XVIIIth
International Fibrinogen Workshop, July 17-20, 2004, Chapel Hill, NC.
61. Yazdani SK, Vlachos PP, Berry JL, Pierrakos O, “Analysis of Fluid-Stent Interaction via Digital Particle Image
Velocimetry,” Proceedings of the ASME IMECE Annual Meeting, November 18-24, 2002, New Orleans, LA
62. Yazdani SK, Vlachos PP, Telionis DP, Pierrakos O, “Effects of Womersley and Reynolds Number On A Symmetric
Compliant Bifurcation,” Proceedings of the ASME IMECE Annual Meeting, November 18-24, 2002, New Orleans, LA.
63. Yazdani SK, Vlachos PP, Berry JL, Etabari A, “Wall Shear Rate Calculations Proximal Of Inserted Stents,” Proceedings
of the 21st Southern Biomedical Engineering Conference, September 28-29, 2002, Bethesda, MD.
64. Berry JL, Vlachos PP, Yazdani SK, “Vascular Stent Fluid Dynamics Using Digital Particle Image Velocimetry,” 4th
International Congress of Pathophysiology, July 2002, Budapest, Hungry
65. Yazdani SK, Vlachos PP, “A Time Resolved DPIV Study of The Flow Characteristics In A Flexible Bifurcation Model,”
BMES Fall Annual Meeting, October 4-7, 2001, Durham, NC.
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Saami K. Yazdani, PhD
MANUSCRIPT REVIEWED FOR:
Journal of Biomechanics
Expert Review of Cardiovascular Therapy
European Heart Journal
Journal of Cardiovascular Pharmacology and Therapeutics
Materials Science and Engineering C
EuroIntervention
Cardiovascular Engineering and Technology
Journal of Vascular Intervention and Radiology
Laboratory Investigation
Interventional Cardiology
Acta Biomaterialia
Cardiovascular Pathology
Journal of The Royal Society Interface
Experimental Techniques
Scientific Reports
Biomedical Engineering Online
INVITIED SEMINARS AND PRESENTATIONS
Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA
GW Institute for Biomedical Engineering, George Washington University, Washington DC
6th Annual European Bifurcation Club Meeting, Budapest, Hungary
Bioengineering Department, George Mason University, Fairfax, VA
Department of Biomedical Engineering, University of Alabama-Birmingham, Birmingham, AL
Department of Anesthesiology, University of Colorado Health Sciences Center, Denver, CO
Department of Mechanical Engineering, University of South Alabama, Mobile, AL
Department of Biomedical Engineering, Saint Louis University, Saint Louis, MO
The Skirball Symposium on Drug Coated Balloon Technologies, Orangeburg, NY
Department of Internal Medicine, Keesler Medical Center, Biloxi, MS
BioAlabama Science Symposium and Annual Meeting, Birmingham, AL
AWARDS & HONORS
ASME International Mechanical Engineering Congress & Exposition, Travel Award
International Symposium for Endovascular Therapy in Miami, Travel Award
Charlotte Biotechnology Conference, 2nd place graduate poster competition
Faculty, Transcatheter Cardiovascular Therapeutics Conference
Invited Commentary for the International Atherosclerosis Society (IAS)
Funded Proposals
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2010
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2010
2010
2011
2011
2012
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2012
2015
2015
2004
2005
2007
2010
2010
RESEARCH ACTIVITY
Yazdani, S. K., "A novel drug delivery system to treat peripheral arterial disease," Sponsored by American Heart
Association, National Scientist Development Grant, Federal, $306,600.00. (July 1, 2015 - June 30, 2019).
Yazdani, S. K. (Principal), Stenson A. (Co-Principal), "A Novel Drug Coated Balloon to Treat Peripheral Disease",
Sponsored by UNIVERSITY OF SOUTH ALABAMA OFFICE OF RESEARCH AND DEVELOPMENT (ORED) PROPOSALS,
Internal to the University, $25,000. (May 1, 2015 - March 31, 2016).
Yazdani, S. K. (Principal), "Tissue Engineering Blood Vessels," Sponsored by UNIVERSITY OF SOUTH ALABAMA
FACULTY DEVELOPMENT COUNCIL (USAFDC) PROPOSALS, Internal to the University, $4,491.00. (April 1, 2013 March 31, 2014).
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