Fall 2013 USC-Aiken BIOL 541 Principles of Biochemistry Syllabus PROFESSOR: Dr. C. Nathan Hancock OFFICE: Room 205, Science Building OFFICE HOURS: By appointment COURSE CREDIT: 3 Credit Hours PREREQUISITES: ACHM 332 and ABIO 121 or consent of instructor CLASS TIME: (200 SCI BLDG) M/W 2:30 to 3:45 CONTACT: 803-641-3390 nathanh@usca.edu TEXT: Fundamentals of Biochemistry: Life at the Molecular Level, 4th Edition Available as an e-book, loose leaf, or hardback 3rd edition may also be acceptable Please read this syllabus carefully and refer to it when you have questions about the course. COURSE DESCRIPTION AND OBJECTIVES: A survey of the fundamental principles of biochemistry. The topics covered include: cellular chemistry, amino acid structure and chemistry, protein structure, carbohydrate chemistry, nucleic acid chemistry, enzyme kinetics and enzyme inhibition. Objectives: Describe the basic role of carbohydrates, lipids, nucleic acids and proteins Understand the relationship between chemical structure and biological function Explore the chemistry behind reactions occurring in living systems GRADE COMPONENTS: Lecture Participation Two Midterm Exams Quizzes and assignments Enzyme Report Final exam 100 pts 200 pts each 200 pts 100 pts 200 pts (10%) (40% total) (20%) (10%) (20%) GRADING SCALE: 100-90% = A; 89-85% = B+; 84-80% = B; 79-75% = C+; 74-70% = C; 69-65% = D+; 64-60% = D; 59-0% = F. GRADING: The exams, in class assignments, and laboratory notebooks will require hand written answers. Answers will only be accepted if they are clearly legible. Late assignments will receive an automatic reduction in score (up to 50% of the possible points). Assignments due at the start of class are considered late 5 minutes after the indicated course time. Assignments can be turned in early if needed. Graded materials will be returned in a reasonable time period. Fall 2013 TENTATIVE LECTURE SCHEDULE Fall 2013 Date Topic 26 Aug Introduction 28 Aug Water 3 Sept Labor Day 4 Sep Water 9 Sep Nucleotides, Nucleic Acids, and Genetic Information 11 Sep Nucleotides, Nucleic Acids, and Genetic Information 16 Sep Carbohydrates 18 Sep Carbohydrates 23 Sep Lipids and Biological Membranes 25 Sep Lipids and Biological Membranes 30 Sep Review 2 Oct 1st Exam 7 Oct Amino Acids 9 Oct Amino Acids (12 Oct - last day to withdraw without WF) 14 Oct Proteins: Primary Structure 16 Oct Proteins: Primary Structure 21 Oct Proteins: Three-Dimensional Structure 23 Oct Proteins: Three-Dimensional Structure 28 Oct Protein Function: 30 Oct Protein Function: 4 Nov Review 6 Nov 2nd Exam 11 Nov Enzyme Catalysis 13 Nov Enzyme Catalysis 18 Nov Enzyme Kinetics, Inhibition, and Control 20 Nov Enzyme Kinetics, Inhibition, and Control 25 Nov Biochemical Signaling 27 Nov Thanksgiving 2 Dec Biochemical Signaling 4 Dec Review 11 Dec Final Exam (2pm) USC-Aiken BIOL 541 Chapter 1 2 2 3 3 8 8 9 9 1-3, 8-9 4 4 5 5 6 6 7 7 4-7 11 11 12 12 13 13 11-13 ATTENDANCE POLICY: “When students enroll in a particular course, they obligate themselves for all the work which may be assigned. Punctual and regular attendance is vital to the discharge of this obligation.” Though attendance will not be taken, you must be present to receive credit for in class assignments, and quizzes. There are also no make-up exams. Should you miss an exam for a documented excusable reason (i.e. sickness or required university event); an alternate exam may be arranged. Only one exam will be treated in this manner; any other missed exams will be counted as a zero. Fall 2013 USC-Aiken BIOL 541 CLASSROOM BEHAVOIR AND PORTABLE ELECTRONIC DEVICES: It is the instructor’s right to remove any student who disrupts or disturbs the proceedings of the class. In extreme cases the professor can request assistance from the University police. If the student who has been ejected causes similar disturbances in subsequent meetings of the class, he/she may be denied admittance to the class for the remainder of the semester and assigned a grade of “F”. The use of any portable electronic devices, including cell phones, pagers, MP3 players, iPods, etc., during class is not allowed for any reason unless prior approval has been given to a student from the instructor or unless required for the course. If you are planning to have any of these devices in class, they must be turned off and stowed away for the duration of the class period. If you use a portable electronic device during a test, quiz, or other assessment, you are eligible to receive a failing grade on that assignment. DISABILITY STATEMENT: If you have a physical, psychological, and/or learning disability that might affect your performance in this class, please contact the Office of Disability Services, B&E 134, (803) 643-6816, as soon as possible. The Disability Services Office will determine appropriate accommodations based on medical documentation. WRITING CENTER: USCA provides a writing center located on room 201 of the H&SS building. If you need extra assistance on any writing assignment for this or any other class that you are taking, please try the writing center. HONOR CODE: Students are expected to abide by the Academic Code of Conduct as described in the Student Handbook. Appropriate disciplinary action will be taken if academic integrity is violated. The following honor pledge is to be written, signed, and dated by the student on all exams and assignments turned into the instructor. “On my honor as a University of South Carolina at Aiken student, I have neither given nor received any unauthorized aid on this assignment/ examination. To the best of my knowledge, I am not in violation of academic honesty.” TEST PROCEDURES: Students will not be allowed to sit in adjacent seats during the exams. If a student must leave during an exam, they forfeit their right to finish the exam. Calculators will only be allowed at the teacher’s discretion.