Fall 2012 USC-Aiken ABIO 541 Principles of Biochemistry Syllabus PROFESSOR: Dr. C. Nathan Hancock OFFICE: Room 205, Science Building OFFICE HOURS: By appointment COURSE CREDIT: 3 Credit Hours PREREQUISITES: ACHM 332 and ABIO 121 or consent of instructor CLASS TIME: (200 SCI BLDG) M/W 2:30 to 3:45 CONTACT: 803-641-3390 nathanh@usca.edu TEXT: Fundamentals of Biochemistry: Life at the Molecular Level, 4th Edition Available as an e-book, loose leaf, or hardback 3rd edition may also be acceptable Please read this syllabus carefully and refer to it when you have questions about the course. COURSE DESCRIPTION AND OBJECTIVES: A survey of the fundamental principles of biochemistry. The topics covered include: cellular chemistry, amino acid structure and chemistry, protein structure, carbohydrate chemistry, nucleic acid chemistry, enzyme kinetics and enzyme inhibition. Objectives: Describe the basic role of carbohydrates, lipids, nucleic acids and proteins Understand the relationship between chemical structure and biological function Explore the chemistry behind reactions occurring in living systems GRADE COMPONENTS: Two Midterm Exams Lecture quizzes and assignments Final exam 200 pts each 400 pts 200 pts (40% total) (40%) (20%) GRADING SCALE: 100-90% = A; 89-85% = B+; 84-80% = B; 79-75% = C+; 74-70% = C; 69-65% = D+; 64-60% = D; 59-0% = F. GRADING: The exams, in class assignments, and laboratory notebooks will require hand written answers. Answers will only be accepted if they are clearly legible. Late assignments will receive an automatic reduction in score (up to 50% of the possible points). Assignments due at the start of class are considered late 5 minutes after the indicated course time. Assignments can be turned in early if needed. Graded materials will be returned in a reasonable time period. Fall 2012 TENTATIVE LECTURE SCHEDULE Spring 2012 Date Topic 27 Aug Introduction 29 Aug Water 3 Sept Labor Day 5 Sept Water 10 Sept Nucleotides, Nucleic Acids, and Genetic Information 12 Sept Nucleotides, Nucleic Acids, and Genetic Information 17 Sept Carbohydrates 19 Sept Carbohydrates 24 Sept Lipids and Biological Membranes 26 Sept Lipids and Biological Membranes 1 Oct Review 3 Oct 1st Exam 8 Oct Amino Acids 10 Oct Amino Acids (12 Oct - last day to withdraw without WF) 15 Oct Proteins: Primary Structure 17 Oct Proteins: Primary Structure 22 Oct Proteins: Three-Dimensional Structure 24 Oct Proteins: Three-Dimensional Structure 29 Oct Protein Function: 31 Oct Protein Function: 5 Nov Review 7 Nov 2nd Exam 12 Nov Enzyme Catalysis 14 Nov Enzyme Catalysis 19 Nov Enzyme Kinetics, Inhibition, and Control 21 Nov Thanksgiving 26 Nov Enzyme Kinetics, Inhibition, and Control 28 Nov Biochemical Signaling 3 Dec Biochemical Signaling 5 Dec Review 12 Dec Final Exam (2pm) USC-Aiken ABIO 541 Chapter 1 2 2 3 3 8 8 9 9 1-3, 8-9 4 4 5 5 6 6 7 7 4-7 11 11 12 12 13 13 11-13 ATTENDANCE POLICY: “When students enroll in a particular course, they obligate themselves for all the work which may be assigned. Punctual and regular attendance is vital to the discharge of this obligation.” Though attendance will not be taken, you must be present to receive credit for in class assignments, and quizzes. There are also no make-up exams. Should you miss an exam for a documented excusable reason (i.e. sickness or required university event); an alternate exam may be arranged. Only one exam will be treated in this manner; any other missed exams will be counted as a zero. Fall 2012 USC-Aiken ABIO 541 CLASSROOM BEHAVOIR AND PORTABLE ELECTRONIC DEVICES: It is the instructor’s right to remove any student who disrupts or disturbs the proceedings of the class. In extreme cases the professor can request assistance from the University police. If the student who has been ejected causes similar disturbances in subsequent meetings of the class, he/she may be denied admittance to the class for the remainder of the semester and assigned a grade of “F”. The use of any portable electronic devices, including cell phones, pagers, MP3 players, iPods, etc., during class is not allowed for any reason unless prior approval has been given to a student from the instructor or unless required for the course. If you are planning to have any of these devices in class, they must be turned off and stowed away for the duration of the class period. If you use a portable electronic device during a test, quiz, or other assessment, you are eligible to receive a failing grade on that assignment. DISABILITY STATEMENT: If you have a physical, psychological, and/or learning disability that might affect your performance in this class, please contact the Office of Disability Services, B&E 134, (803) 643-6816, as soon as possible. The Office of Disability Services will determine appropriate accommodations based on documentation. WRITING CENTER: USCA provides a writing center located on room 201 of the H&SS building. If you need extra assistance on any writing assignment for this or any other class that you are taking, please try the writing center. HONOR CODE: Students are expected to abide by the Academic Code of Conduct as described in the Student Handbook. Appropriate disciplinary action will be taken if academic integrity is violated. The following honor pledge is to be written, signed, and dated by the student on all exams and assignments turned into the instructor. “On my honor as a University of South Carolina at Aiken student, I have neither given nor received any unauthorized aid on this assignment/ examination. To the best of my knowledge, I am not in violation of academic honesty.” TEST PROCEDURES: Students will not be allowed to sit in adjacent seats during the exams. If a student must leave during an exam, they forfeit their right to finish the exam. Calculators will only be allowed at the teacher’s discretion.