The American Journal of Sports Medicine http://ajs.sagepub.com/ Predictive Value of Prior Injury on Career in Professional American Football Is Affected by Player Position Robert H. Brophy, Stephen Lyman, Eric L. Chehab, Ronnie P. Barnes, Scott A. Rodeo and Russell F. Warren Am J Sports Med 2009 37: 768 originally published online February 19, 2009 DOI: 10.1177/0363546508329542 The online version of this article can be found at: http://ajs.sagepub.com/content/37/4/768 Published by: http://www.sagepublications.com On behalf of: American Orthopaedic Society for Sports Medicine Additional services and information for The American Journal of Sports Medicine can be found at: Email Alerts: http://ajs.sagepub.com/cgi/alerts Subscriptions: http://ajs.sagepub.com/subscriptions Reprints: http://www.sagepub.com/journalsReprints.nav Permissions: http://www.sagepub.com/journalsPermissions.nav >> Version of Record - Mar 31, 2009 OnlineFirst Version of Record - Feb 19, 2009 What is This? Downloaded from ajs.sagepub.com at UNIV OF DELAWARE LIB on March 5, 2014 Predictive Article TitleValue of Prior Injury on Career in Professional Article Subtitle American Football Is Affected by AuthorPlayer Position Affiliation Robert H. Brophy,* MD, Stephen Lyman, PhD, Eric L. Chehab, MD, Ronnie P. Barnes, Scott A. Rodeo, MD, and Russell F. Warren, MD From the Hospital for covers Special The abstract goes here and two Surgery, columns. New York, New York The abstract goes here and covers two columns. The abstract goes here and covers two columns. Background: The National Football League holds an annual combine where individual teams evaluate college football players The abstract goes here and covers two columns. likely to be drafted for physical skills, review players’ medical history and imaging studies, and perform a physical examination. Purpose: The purpose of this study was to test the effect of specific diagnoses and surgical procedures on the likelihood of playing KEYlength WORDS list of key words goes and of career in the league byhere position. Study Design: Cohort study; Level of evidence, 3. Methods: A database for all players reviewed at the annual National Football League Combine by the medical staff of 1 National Football League team from 1987 to 2000 was created, including each player’s orthopaedic rating, diagnoses, surgical procedures, number of games played, and number of seasons played in the National Football League. Athletes were grouped by position as follows: offensive backfield, offensive receiver, offensive line, quarterback, tight end, defensive line, defensive secondary, linebacker, and kicker. The percentage of athletes who played in the National Football League was calculated by position for each specific diagnosis and surgery. Results: The effect of injury on the likelihood of playing in the league varied by position. Anterior cruciate ligament injury significantly lowered the likelihood of playing in the league for defensive linemen (P = .03) and linebackers (P = .04). Meniscal injury significantly reduced the probability of playing (P < .05) and length of career (P = .002) for athletes in the defensive secondary. Shoulder instability had a significant effect on playing in the league for offensive (P = .03) and defensive linemen (P = .02), and shortened the length of career for defensive linemen (P = .016). Spondylolisthesis did not significantly reduce the chance of playing in the league for any position, while a history of spondylolysis had a significant effect for running backs (P = .01). Miscellaneous injuries (eg. acromioclavicular joint, knee medial collateral ligament, carpal fractures) had isolated position-specific effects. Conclusion: The significant injuries and diagnoses appear congruent with the position-specific demands placed on the athletes. This information is useful to physicians and athletic trainers caring for college football athletes as well as those assessing these athletes at the National Football League Combine. Keywords: college football; National Football League (NFL); combine; anterior cruciate ligament (ACL); shoulder; meniscus The database includes each player’s position, collegiate division, diagnoses, and surgical procedures. A previous study based on this database reported the prevalence and trends of musculoskeletal disorders in this population.1 The most common diagnoses varied by position, but the most common procedures were similar across different positions in this cohort. A follow-up study combined this database with career statistics from Elias Sports Bureau (New York, New York) on each athlete in the NFL to demonstrate that the orthopaedic rating system predicts the likelihood of playing in the league and the length of career in terms of games played in the league.2 Among all participants at the combine, athletes with a history of shoulder instability, meniscal injury, and anterior cruciate ligament (ACL) injury, as The National Football League (NFL) holds an annual combine, organized and operated by National Football Scouting Inc, where individual teams evaluate college football players who are likely to be drafted. As part of the process, the teams review the players’ medical history and imaging studies and perform a physical examination. A database for all players reviewed at the annual combine by the medical staff of 1 NFL team from 1987-2000 was created. Presented at the interim meeting of the AOSSM, San Francisco, California, March 2001. *Address Brophy, MD,1,14532 Address correspondence correspondencetotoRobert AuthorH.1, Address City, South State,Outer Zip, Forty Drive, Chesterfield, MO 63017 (e-mail: brophyr@wudosis.wustl.edu). Affiliation. No conflict of interest Anypotential author’s notes could also go declared. here. The The American American Journal Journal of of Sports Sports Medicine, Medicine, Vol. Vol. 37, 33, No. No. 4X DOI: DOI: 10.1177/0363546508329542 10.1177/1073858403253460 © © 2009 2005 American American Orthopaedic Orthopaedic Society Society for for Sports Sports Medicine Medicine 768 Downloaded from ajs.sagepub.com at UNIV OF DELAWARE LIB on March 5, 2014 Predictive Value of Prior Injury on Football Career Affected by Position 769 Vol. 37, No. 4, 2009 TABLE 1 Summary of the Athletes at the National Football League Combine by Position, 1987-2000 Position Offensive backfield Offensive receiver Offensive line Tight end Quarterback Defensive line Defensive secondary Linebacker Kicker Average Length of Career Number at Combine Number Played in League Percentage Who Played Games Seasons 713 692 870 277 322 929 546 494 161 402 372 471 168 143 612 328 308 41 56.4 53.8 54.1 60.7 44.4 65.9 60.1 62.4 25.5 61.9 ± 48.3 60.8 ± 51.4 73.4 ± 54.6 71.5 ± 50.4 52.4 ± 58.7 72.6 ± 53.5 68.1 ± 51.4 70.7 ± 53.7 99.1 ± 74.2 5.5 ± 3.3 5.5 ± 3.4 6.7 ± 3.4 6.2 ± 3.4 7.3 ± 4.4 6.2 ± 3.5 5.7 ± 3.4 6.0 ± 3.5 7.7 ± 5.2 well as individuals who had undergone ACL reconstruction, were less likely to play in the league than athletes without these diagnoses or surgery.2 Given the varied demands placed on athletes depending on the position they play, the effect of diagnoses and surgical procedures on future success in the NFL likely depends on position. For example, a recent study demonstrated that player position does influence the type of shoulder injury seen among elite collegiate football athletes.8 The purpose of this study was to test the hypothesis that the effect of specific diagnoses and procedures on the likelihood of playing in the league and length of career in the league varies by position. we tested whether an increasing number of diagnoses or procedures made it less likely for athletes who played a particular position to play in the league. Survival analysis using Cox regression was performed to determine whether ACL injury/reconstruction, meniscal injury, and shoulder instability/stabilization affected length of career in the NFL by position. All models were adjusted for draft position, which was considered a surrogate for talent/skill—a presumptive predictor of career length independent of injury history. A P value of < .05 was considered statistically significant. All analyses were performed using SAS for Windows (SAS Institute, Cary, North Carolina). RESULTS METHODS A database for all players reviewed at the annual combine by the medical staff of 1 NFL team from 1987 to 2000 was created from the records of the team’s head physician, including each player’s position, collegiate division, diagnoses, and surgical procedures.1 We then linked this database to a proprietary data set purchased from Elias Sports Bureau, the official statistician of the NFL, containing the round drafted, number of seasons, and number of regular season games played in the NFL for each athlete who first played in the league from 1987 to 2001.2 Athletes were grouped by position: offensive backfield, offensive receiver, offensive line, quarterback, tight end, defensive line, defensive secondary, linebacker, and kicker. The overall number of athletes at the combine, and the number and percentage who played at least 1 game in the NFL, were calculated for each position. For each position, the percentage of all athletes with a history of a particular diagnosis/ surgery who played in the league was compared with the percentage of all athletes without that diagnosis/surgery who played in the league. Finally, the average length of career in the NFL was calculated for each position. Chi-square tests were calculated to compare the frequency of athletes in a particular position with a given diagnosis or procedure playing in the league to the frequency of all other athletes in that position without that diagnosis or procedure playing in the league. In addition, Overall, 56% (2845 of 5004) of the players at the combine played at least 1 game in the NFL. The overall number of athletes at the combine, the number and percentage who played at least 1 game in the NFL, and the mean length of career in games and years for each position are shown in Table 1. The effect of ACL injury and reconstruction by position on the percentage of athletes playing in the league is shown in Table 2. Athletes with a history of ACL reconstruction were included in both groups; athletes with a history of an ACL injury but no history of reconstruction had a severe ACL sprain or a chronic injury that had been treated nonoperatively. A history of ACL injury resulted in a significantly lower percentage of defensive linemen (54% [37 of 69] vs 67% [575 of 860]; P = .03) and linebackers (48% [21 of 44] vs 64% [277 of 450]; P = .04) playing professional football. Anterior cruciate ligament reconstruction resulted in a significantly smaller percentage of linebackers (46% [15 of 33] vs 64% [293 of 461]; P = .04), offensive linemen (40% [18 of 45] vs 55% [453 of 825]; P = .05), and defensive linemen (54% [29 of 54] vs 67% [583 of 875]; P = .05) playing professional football. Anterior cruciate ligament injury (P = .002) and ACL reconstruction (P = .003) resulted in a significantly shorter playing career for offensive linemen (Figure 1), but did not affect length of career for any other positions. Based on the hazard ratio, offensive linemen with a history of ACL injury were 2.0 times Downloaded from ajs.sagepub.com at UNIV OF DELAWARE LIB on March 5, 2014 770 Brophy et al The American Journal of Sports Medicine TABLE 2 Effect of ACL Injury and ACL Reconstruction by Positiona History of ACL Injury Position Present, % Offensive backfield Offensive receiver Offensive line Tight end Quarterback Defensive line Defensive secondary Linebacker Kicker 49 48 43 47 50 54 50 48 33 History of ACL Reconstruction Not Present, % (34/69) (21/44) (26/61)f (8/17) (9/18) (37/69)b (17/34) (21/44)c (3/9) 57 54 55 62 44 67 61 64 25 (368/644) (351/648) (445/809)f (160/260) (134/304) (575/860)b (311/512) (287/450)c (38/152) Present, % 46 49 40 57 47 54 41 46 25 (24/52) (18/37) (18/45)d (8/14) (7/15) (29/54)e (9/22)f (15/33)c (2/8) Not Present, % 57 (378/661) 54 (354/655) 55 (453/825)d 61 (160/263) 44 (136/307) 67 (583/875)e 61 (319/524)f 64 (293/461)c 26 (39/153) a Athletes with a history of anterior cruciate ligament (ACL) reconstruction were included in both groups; athletes with a history of an ACL injury but no history of reconstruction usually had a severe ACL sprain or a chronic injury that had been treated nonoperatively. b P = .03. c P = .04. d P = .05. e P = .05. f P = .06. Figure 1. Survival analysis of offensive linemen in the National Football League. more likely to have a shorter career than those without a history of ACL injury, while those with a history of ACL reconstruction were 2.2 times more likely to have a short career than those without. The effect of meniscal injury by position on the likelihood of playing in the NFL is shown in Table 3. The only position with a statistically significant difference was the secondary (48% [29/60] vs 62% [299/486]; P = .049). All other positions except running backs faced a nonsignificant reduction in the percentage of athletes playing professional football if they had a history of meniscal injury. Among running backs, 60% of athletes with a history of meniscal injury played at least 1 game in the NFL, whereas 56% of athletes without a history of previous meniscal injury played at least 1 game in the NFL. Meniscal injury shortened the length of career for players in the defensive secondary (P = .002) (Figure 2). Athletes in the secondary with a meniscal injury were 2.0 times more likely to have a shorter career than those without a history of meniscal injury. Shoulder instability reduced the percentage of offensive (43.9% [43/98] vs 55.4% [428/772]; P = .03) and defensive (54.3% [44/81] vs 67.0% [568/848]; P = .02) linemen playing in the NFL (Table 4). Shoulder stabilization did not significantly decrease the percentage of athletes playing in the league for any position, although there was a trend Downloaded from ajs.sagepub.com at UNIV OF DELAWARE LIB on March 5, 2014 Predictive Value of Prior Injury on Football Career Affected by Position 771 Vol. 37, No. 4, 2009 TABLE 3 Effect of Meniscal Injury by Positiona Position Offensive backfield Offensive receiver Offensive line Tight end Quarterback Defensive line Defensive secondaryb Linebacker Kicker Meniscal Injury No Meniscal Injury Played in NFL, % Played in NFL, % 60 47 47 58 38 59 48 51 25 (48/80) (34/73) (54/114) (18/31) (12/32) (70/118) (29/60) (24/47) (3/12) 56 55 55 61 45 67 62 64 26 (354/633) (338/619) (417/756) (150/246) (131/290) (542/811) (299/486) (284/447) (38/149) a NFL, National Football League. P = .049. b among defensive linemen (53.7% [22/41] vs 66.4% [590/888]; P = .09). Shoulder instability and shoulder stabilization reduced the length of career for receivers (P = .044 and .014, respectively) and defensive linemen (P = .016 and .044, respectively) (Figures 3 and 4). For receivers, shoulder instability and shoulder stabilization increased the likelihood of a shorter career by a factor of 1.5 and 1.6, respectively. For defensive linemen, the effect was 1.7 (shoulder instability) and 2.4 (shoulder stabilization). A history of spondylolysis reduced the percentage of running backs playing in the league (18.2% [2/11] vs 57% [400/702]; P = .01). There was a trend toward fewer receivers playing in the league with a history of spondylolysis (28.6% [4/14] vs 54.3% [368/678]; P = .06). Spondylolisthesis did not significantly reduce percentage of athletes playing in the NFL for any position. Among offensive linemen, 18 of 24 athletes (75%) with spondylolisthesis played in the league, which was significantly higher than the percentage of offensive linemen without spondylolisthesis who played at least 1 game in the NFL (53.6%) (P = .04). Other significant findings are summarized in Table 5. An increased number of surgical procedures in offensive and defensive linemen significantly decreased the percentage of athletes playing in the league. In other positions, an increasing number of procedures did not have a significant effect. DISCUSSION Figure 2. Survival analysis of defensive secondary in the National Football League. The effect of specific diagnoses and procedures on the NFL career of college American football athletes does vary by position. Defensive linemen who participated in the NFL Combine had the greatest probability of playing at least 1 game in the league, while quarterbacks and kickers had the lowest probability of playing professional football. In terms of seasons in the league, athletes at speed positions such as running backs, receivers, and the defensive secondary had the shortest careers, while quarterbacks and kickers lasted the most seasons in the league. However, quarterbacks had the shortest career length of all positions TABLE 4 Effect of Shoulder Instability and Shoulder Stabilization by Positiona Position Offensive backfield Offensive receiver Offensive line Tight end Quarterback Defensive line Defensive secondary Linebacker Kickers Shoulder Instability No Shoulder Instability Shoulder Stabilization No Shoulder Stabilization Played in NFL, % Played in NFL, % Played in NFL, % Played in NFL, % 54 49 44 58 48 54 53 63 27 (28/52) (18/37) (43/98)b (18/31) (13/27) (44/81)c (27/51) (35/56) (3/11) 57 54 54 61 44 67 61 62 25 (374/661) (354/655) (428/672)b (150/246) (130/295) (568/848)c (301/495) (273/438) (38/150) 54 67 48 62 50 54 48 63 40 (14/26) (8/12) (20/42) (8/13) (8/16) (22/41)d (12/25) (19/30) (2/5) a 56 54 55 61 44 66 61 62 25 (388/687) (364/680) (451/728) (160/264) (135/306) (590/888)d (316/521) (289/464) (39/156) Some athletes with a history of shoulder instability did not have a history of shoulder stabilization. NFL, National Football League. P = .03. c P = .02. d P = .09. b Downloaded from ajs.sagepub.com at UNIV OF DELAWARE LIB on March 5, 2014 772 Brophy et al The American Journal of Sports Medicine Figure 3. Survival analysis of wide receivers in the National Football League. Figure 4. Survival analysis of defensive linemen in the National Football League. in terms of games played while kickers had the longest career in games played. The apparent discrepancy in the quarterback data probably reflects the need for backup quarterbacks, who may be in the league for several seasons but see relatively little playing time. Clearly one of the most significant injuries to a collegiate football player is a rupture of the ACL. From 1987 to 2001, ACL reconstruction was the third most common procedure among participants at the combine, behind meniscectomy and knee arthroscopy (not otherwise specified), and ACL injury was among the top 15 diagnoses at the combine.1 In our previous study including all participants at the combine, ACL injury and ACL reconstruction significantly reduced the percentage of athletes playing in the NFL.2 By position, ACL injury significantly reduced the percentage of defensive linemen and linebackers playing in the league, and showed a strong negative trend for offensive linemen. Anterior cruciate ligament reconstruction resulted in a Downloaded from ajs.sagepub.com at UNIV OF DELAWARE LIB on March 5, 2014 Predictive Value of Prior Injury on Football Career Affected by Position 773 Vol. 37, No. 4, 2009 TABLE 5 Other Diagnoses/Procedures by Position That Decrease the Probability of Playing in the NFLa Position Offensive backfield Offensive receiver Offensive line Tight end Quarterback Defensive line Defensive secondary Linebacker Kicker Diagnosis/Procedure Played Did Not Play Spondylolysis Spondylolysis Carpal fractures Rotator cuff repair Knee articular cartilage surgery LCL (knee) MCL (knee) Forearm fracture Rotator cuff injury na AC joint injury na 2 4 5 0 0 0 16 1 10 na 27 na 9 10 13 4 4 3 36 10 13 na 27 na Total 11 14 18 4 4 3 52 11 23 na 54 na Percentage Played in League 18 29 28 0 0 0 31 9 44 vs vs vs vs vs vs vs vs vs 57 (P 54 (P 55 (P 54 (P 54 (P 61 (P 47 (P 46 (P 67 (P na 50 vs 64 (P na = = = = = = = = = .01) .06) .02) .04) .04) .06) .03) .03) .02) = .05) a NFL, National Football League; LCL, lateral collateral ligament; MCL, medial collateral ligament; AC, acromioclavicular; na, not available. lower percentage of linebackers playing professional football and a strong trend toward less success for offensive and defensive linemen, as well as athletes in the defensive secondary. Although not always statistically significant, ACL injury and ACL reconstruction resulted in a smaller percentage of athletes playing in the league in all other positions except for quarterbacks and kickers. Approximately half the quarterbacks with an ACL injury and a little over 25% of kickers with ACL injuries played in the league. Neither of these rates was significantly different from the overall rate of success for noninjured athletes in those positions. A recent study by Carey et al3 examined the effect of ACL injury on running backs and wide receivers already playing in the NFL. Almost 80% of these athletes returned to play and the performance of those who did play was reduced by a third. Although our previous study suggested that the treatment of ACL injury has improved over time,1 ACL injury reduces the chances of making the transition from collegiate football player to the professional level,2 particularly for linemen and linebackers. However, the magnitude of the difference in terms of the percentage of athletes who play in the NFL is smaller than might be expected for other positions. Among kickers and quarterbacks, for example, athletes with a history of ACL injury had the same percentage or higher of going on to play in the league as athletes without such an injury, suggesting that treatment for these injuries can be very effective. Length of career was significantly affected by ACL injury and reconstruction only among offensive linemen. Combined with the reduced likelihood of playing in the league for offensive linemen, it appears that injury to the ACL may be particularly challenging for these athletes. Future research should study the specific effects of ACL injury and reconstruction on offensive linemen and what influences their ability to continue playing football after such an injury. Meniscal injury has been shown to reduce the likelihood of playing in the NFL for all participants at the combine.2 Although meniscal injury only had a significant negative effect for athletes in the defensive secondary, meniscal injury did reduce the percentage of athletes playing in the league in all positions except running backs. This is particularly relevant because meniscal injury was the sixth most common diagnosis and meniscectomy was the most common procedure among all athletes at the combine.1 The effect of meniscal injury on athletes in the secondary is particularly important as it reduces their likelihood of playing in the league and their longevity if they make it to the NFL. The running and cutting demands on these athletes may make them particularly sensitive to the effects of meniscal injury, and this presents another area of opportunity for future research. It is very interesting that meniscal injury did not decrease the percentage of running backs playing in the NFL. In this sizable cohort of 80 running backs with a history of meniscal injury, 48 of them played at least 1 game of professional football. Furthermore, meniscal injury did not reduce their longevity in the league. The other injury that was shown to have a negative effect on playing in the NFL for all combine participants was shoulder instability.2 Shoulder instability was the ninth most common diagnosis at the NFL combine and shoulder stabilization was the fourth most common procedure.1 A recent MRI study found that football players are 15 times more likely to have a posterior labral tear than non-football players.4 Shoulder instability reduces the percentage of both offensive and defensive linemen who play in the NFL and reduces the length of career for defensive linemen who play in the league. Although rotator cuff injury is less common than shoulder instability among these athletes, rotator cuff injury lowered the percentage of defensive linemen who played professional football and rotator cuff surgery did the same for offensive linemen. A recent study showed that 50% of elite college football athletes have a history of shoulder injury and a third have a history of shoulder surgery.8 While injuries were more common in quarterbacks and defensive backs, surgery was more common in linebackers and linemen. Anterior instability reconstruction made up 48% of those surgeries; posterior instability surgery and rotator cuff surgery each made up another 10%. Linemen were more likely to have Downloaded from ajs.sagepub.com at UNIV OF DELAWARE LIB on March 5, 2014 774 Brophy et al The American Journal of Sports Medicine posterior instability and rotator cuff injuries, making up 71% and 41% of these injuries, respectively. Of note, rotator cuff injuries accounted for 25% of all offensive linemen shoulder injuries in that study. Another study reporting on full-thickness rotator cuff injuries in professional football players reported that offensive linemen were most commonly affected, with 22 of 51 tears occurring in offensive linemen.5 In conjunction with our results, it is clear that shoulder injury can be damaging to the career prospects of a collegiate football lineman. The findings in the spine are contrary to the perception of spondylolisthesis as an unfavorable finding in elite athletes.21 In a survey of NFL team physicians, 64% believed that the presence of spondylolisthesis implies a poor prognosis and 96% downgraded the rating of players with known spondylolisthesis before the NFL draft.19 In our study, spondylolisthesis did not reduce the percentage of athletes playing in the league, even among linemen. At the combine, most of these injuries are probably chronic and asymptomatic. Because athletes with a symptomatic spondylolysis/spondylolisthesis are unlikely to be invited to the combine, our findings are not necessarily applicable to all collegiate linemen. In contrast to spondylolisthesis, spondyloysis did have a negative effect on running backs and approached significance in receivers. Previous studies suggested that spondylolysis was not a significant finding in collegiate football athletes.10,18 However, our study suggests that spondylolysis is a more significant finding in skilled position players than spondylolisthesis in linemen at the combine. The fact that no offensive linemen played in the league after knee articular cartilage surgery is of clinical interest. Among all participants at the combine over this study period, 22 athletes had a history of knee articular cartilage surgery and only 10 of them played at least 1 game in the league. Cartilage lesions can be a difficult problem to treat in any cohort and they are particularly challenging in elite athletes facing the demands of the NFL. Steadman et al20 reported on the results of microfracture for full-thickness chondral lesions in NFL players. They reported that 19 of 25 players (76%) returned to play the following season, while 9 of 25 (36%) continued to play at average follow-up of 4.5 years (range, 2-13 years). Fourteen of the 25 players were linemen, although this study did not report results by position. A prior study that reported on high-impact athletics after microfracture found that only 3 of 9 football players returned to their sport after this surgery.12 This may be related to player size, as a higher body mass index (BMI), specifically a BMI >30, has been shown to be associated with worse outcomes after microfracture.11 This is particularly relevant for linemen, who had the highest BMI in a recent study of 1 NFL team (offensive line BMI, 37.1 ± 1.9; defensive line BMI, 34.6 ± 1.4).9 New treatments are becoming available, and although there are some reports of using these techniques in athletes,6,7,13 no results specific to American football are available to date. Cartilage lesions remain a difficult clinical problem, particularly in high-demand, highperformance athletes such as those in the NFL. Other injuries appear to have position-specific effects that are consistent with the demands of the position. The negative effect of forearm fractures on quarterbacks is not surprising. Carpal fractures may make it difficult for offensive linemen to block. The most common fracture in the wrist among athletes is the scaphoid,16 and previous studies have described both conservative14,16,17 and surgical14,15,16 treatment. We reviewed our data to see if surgery had any effect on outcome. A total of 6 offensive linemen had surgical treatment of their carpal fractures and only 1 (17%) played in the league. Twelve offensive linemen had carpal fractures that were treated nonoperatively and 4 of them (33%) played in the league. With the small numbers in this cohort, the difference was not significant. Furthermore, this small retrospective group does not control for injury severity and more severe injuries may have been more likely to be treated with surgery. The significant effect of a knee medial collateral ligament (MCL) injury on quarterbacks is surprising. We hypothesized that this relatively benign injury reduced the probability of quarterbacks playing in the NFL because it was associated with more significant combined knee ligamentous injury. However, the data did not support this theory. A history of combined ACL-MCL injury was present in only 3 of the 36 quarterbacks at the combine with an MCL injury who did not play in the NFL. By comparison, 4 of the 16 quarterbacks with an MCL injury who did play in the NFL also had an ACL injury. Further investigation is warranted to identify how these injuries may be detrimental to the quarterback athlete. Although this study uses retrospectively collected data from the combine, given the high stakes at risk, the assessment process at the combine is likely both thorough and accurate. To play at least 1 regular season game in the NFL, the athlete has to be functioning at a level at which an NFL coaching staff believes the individual is able to withstand the rigors of professional football competition. Differentiating athletes based on playing 1 game in the NFL is a limitation, although any threshold will be arbitrary and subject to criticism. A higher threshold requiring more games in the league could be more sensitive to other factors, such as athletic talent, relative opportunity based on roster depth, and new injuries incurred in the NFL. By analyzing the length of career as well, we also assessed whether these injuries affect the durability of these athletes. Injuries that reduced the likelihood of playing in the league for athletes in a particular position often reduced the length of career for the same cohort. Analyzing the data by position obviously reduces the power of our study by reducing the sample size. This may have been particularly relevant in the positions with fewer subjects, such as kickers (161), tight ends (275), and quarterbacks (322). However, our database is perhaps the largest collection of comprehensive data available on this population of elite athletes. Despite the limitations, the findings in this study provide new information on how certain injuries may affect collegiate football athletes in different positions. Comparing all athletes with a specific diagnosis/procedure to all other athletes without that specific diagnosis/procedure is a significant limitation as it does not take into account the effect of other diagnoses and/or procedures. However, with the large number of athletes in this database, it is Downloaded from ajs.sagepub.com at UNIV OF DELAWARE LIB on March 5, 2014 Vol. 37, No. 4, 2009 Predictive Value of Prior Injury on Football Career Affected by Position 775 reasonable to assume that the distribution of the other diagnoses and procedures does not bias the results of the comparison. On the other hand, limiting the study population to athletes with a history of only 1 particular diagnosis or surgery, for example, would further limit the power of the study and probably introduce a different, and perhaps more significant, source of bias. Although the study does not adjust for differences by position in the number of athletes at the combine or the number of spots on the field and roster, all comparisons are intraposition, not interposition, so these differences should not alter the analysis. Another limitation is the lack of specific information about each diagnosis; for example, meniscal injury includes both medial and lateral meniscus pathology. Shoulder instability includes anterior and posterior injuries, and we do not know whether shoulder stabilization was open or arthroscopic. Finally, the findings in this study only apply to athletes invited to the combine. This analysis does not account for the effect of injuries on the likelihood to be invited to the combine. Therefore, the findings cannot necessarily be extrapolated to the average collegiate football athlete. College football players should be advised of how specific injuries influence the percentage of athletes who play professional football based on position and their durability in the league. The data reported herein should not be accepted as an absolute predictor for the probability of success or failure, but rather as a general guide on how past injuries may influence the potential for a professional football career. The effect of these injuries does depend on the position that the athlete plays, and the significant injuries and diagnoses appear congruent with the position-specific demands placed on the athletes. This information is useful to physicians and athletic trainers caring for and advising aspiring professional football athletes as well as those assessing these athletes at the NFL Combine. REFERENCES 1.Brophy RH, Barnes R, Rodeo SA, Warren RF. Prevalence of musculoskeletal disorders at the NFL Combine—trends from 1987 to 2000. Med Sci Sports Exerc. 2007;39:22-27. 2.Brophy RH, Chehab EL, Barnes RP, Lyman S, Rodeo SA, Warren RF. Predictive value of orthopedic evaluation and injury history at the NFL combine. Med Sci Sports Exerc. 2008;40:1368-1372. 3.Carey JL, Huffman GR, Parekh SG, Sennett BJ. Outcomes of anterior cruciate ligament injuries to running backs and wide receivers in the National Football League. Am J Sports Med. 2006;34:1911-1917. 4.Escobedo EM, Richardson ML, Schulz YB, Hunter JC, Green JR 3rd, Messick KJ. Increased risk of posterior glenoid labrum tears in football players. AJR Am J Roentgenol. 2007;188:193-197. 5.Foulk DA, Darmelio MP, Rettig AC, Misamore G. Full-thickness rotatorcuff tears in professional football players. Am J Orthop. 2002;31: 622-624. 6.Gudas R, Kalesinskas RJ, Kimtys V, et al. A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint in young athletes. Arthroscopy. 2005;21:1066-1075. 7.Gudas R, Stankevicius E, Monastyreckiene E, Pranys D, Kalesinskas RJ. Osteochondral autologous transplantation versus microfracture for the treatment of articular cartilage defects in the knee joint in athletes. Knee Surg Sports Traumatol Arthrosc. 2006;14:834-842. 8.Kaplan LD, Flanigan DC, Norwig J, Jost P, Bradley J. Prevalence and variance of shoulder injuries in elite collegiate football players. Am J Sports Med. 2005;33:1142-1146. 9.Kraemer WJ, Torine JC, Silvestre R, et al. Body size and composition of National Football League players. J Strength Cond Res. 2005;19: 485-489. 10.McCarroll JR, Miller JM, Ritter MA. Lumbar spondylolysis and spondylolisthesis in college football players: a prospective study. Am J Sports Med. 1986;14:404-406. 11.Mithoefer K, Williams RJ 3rd, Warren RF, et al. The microfracture technique for the treatment of articular cartilage lesions in the knee: a prospective cohort study. J Bone Joint Surg Am. 2005;87:1911-1920. 12.Mithoefer K, Williams RJ 3rd, Warren RF, Wickiewicz TL, Marx RG. High-impact athletics after knee articular cartilage repair: a prospective evaluation of the microfracture technique. Am J Sports Med. 2006;34:1413-1418. 13.Mithofer K, Peterson L, Mandelbaum BR, Minas T. Articular cartilage repair in soccer players with autologous chondrocyte transplantation: functional outcome and return to competition. Am J Sports Med. 2005;33:1639-1646. 14.Rettig AC. Athletic injuries of the wrist and hand: part I, traumatic injuries of the wrist. Am J Sports Med. 2003;31:1038-1048. 15.Rettig AC, Kollias SC. Internal fixation of acute stable scaphoid fractures in the athlete. Am J Sports Med. 1996;24:182-186. 16.Rettig AC, Weidenbener EJ, Gloyeske R. Alternative management of midthird scaphoid fractures in the athlete. Am J Sports Med. 1994;22: 711-714. 17.Riester JN, Baker BE, Mosher JF, Lowe D. A review of scaphoid fracture healing in competitive athletes. Am J Sports Med. 1985;13:159-161. 18.Semon RL, Spengler D. Significance of lumbar spondylolysis in college football players. Spine. 1981;6:172-174. 19.Shaffer B, Wiesel S, Lauerman W. Spondylolisthesis in the elite football player: an epidemiologic study in the NCAA and NFL. J Spinal Disord. 1997;10:365-370. 20.Steadman JR, Miller BS, Karas SG, Schlegel TF, Briggs KK, Hawkins RJ. The microfracture technique in the treatment of full-thickness chondral lesions of the knee in National Football League players. J Knee Surg. 2003;16:83-86. 21.Tallarico RA, Madom IA, Palumbo MA. Spondylolysis and spondylolisthesis in the athlete. Sports Med Arthrosc. 2008;16:32-38. Downloaded from ajs.sagepub.com at UNIV OF DELAWARE LIB on March 5, 2014