TRAUMATIC AMNESIAS: psychogenic forgetting? • Global retrograde amnesias and fugues – Sudden loss of autobiographical memory and identity – May be triggered by severe psychological stress – Some evidence for link to earlier physical trauma or disease – Pattern of recovery is diverse • Sudden, quick and complete • Gradual and incomplete • Failure of recovery – Rarer than the media suggest • < 1% of clinical casework in some estimates Richard Gere and Ed Norton in Primal Fear Renee Zellweger As Nurse Betty "A fugue is a combination of amnesia and physical fright. The individual flees from his customary surroundings toward the assumptions of a new identity.“ American Psychiatric Association 1994 Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition • Recovery from Fugue states: a sampler – Libby Morris: lost from a shopping mall • Rapid, almost complete recovery • Amnesia for fugue period – Ricky Stephenson: AWOL • Unresolved after two years • Relearning his past – Jody Roberts: You’re a thousand miles away • Unresolved after 12 years • New, stable identity established – James Smith: Rip van Winkle awakes • Fugue ends after 25 years • “gap” before recovery • Amnesia for fugue period • Dissociative Identity Disorder (aka Multiple Personality Disorder): A capsule history – Rash of cases in late 19th century • Seen as symptom of “hysteria” – Extremely rare until 1980’s • Pre 1970’s < 100; ’85 – ’89, c. 40,000 • Media and professional attention – DID and the recovered memory movement • Often linked to recovered memories of abuse, other more bizarre experiences • Often evolves during aggressive therapy – 1990’s: backlash of skepticism Recanters in court CHARACTERISTICS OF DID • The person – Associated with early, chronic abuse or trauma (est. 50-70% sexual or physical abuse incidence) – And with “a trail of psychopathology” – Tend to be highly hypnotizable • Memory aspects – Autobiographical dissociation may be complete, or “leaky” – Some evidence for implicit memory “across identities” • The outlook – May resolve with therapy or time – Difficult to separate “genuine” cases from role-playing – Relation to everyday “dissociations” in mood and memory – Relation to fugues? DID: an fMRI study (Tsai, et al. 1999) • 47-yr old woman – Severe childhood abuse – DID and PTSD diagnosis; long-term therapy – Hippocampal volume reduced 1.1 cm3 vs. 2.6 +/-.02 cm3 – Normal-range score (106) on WMS • Cued switch to/from: – Alter personality (“Guardian” 8 yr old) – Irrelevant personality (“Player” 8 yr old) • Avg. 30 seconds to switch – fMRI during switch, maintenance – Right hippocampus: • Inhibition during switch to alter • Activation during switch from alter • No changes during “control” switches