Chemical Compatibility (continued)
Acids
Alcohols
Bases
Esters
Glycols
HH*
Ac
eto
ne
(10
Ac
%)
eto
ne
(20
Me
%
thy
)
l et
hyl
Ph
k
eno
eto
l (0
ne
.5%
(M
Ac
EK
)
eto
) (1
nit
0%
rile
)
Alc
(20
ono
%
)
x◆
(1%
Am
)
mo
niu
m
Am
c
hlo
mo
rid
niu
e(
m
Ca
1%
sul
lciu
)
f
a
m
te
c
hlo
Dim
r
i
d
eth
e(
yl f
5%
orm
)
Dim
am
eth
ide
yl f
(DM
orm
Dim
am
F)
eth
(<
ide
yl f
5%
(20
orm
Dim
)
%
am
eth
)
ide
yl s
(10
ulf
Dim
oxi
0%
eth
de
)
yl s
(DM
ulf
Dim
SO
oxi
eth
) (<
de
yl s
(20
5%
ulf
Dis
%)
)
oxi
odi
de
um
(10
sal
For
0%
to
ma
)
fE
lde
DT
hyd
A(
For
10%
e(
ma
1%
lde
)
)
hyd
Glu
e(
tal
5%
deh
)
yde
Gly
(0.
cer
5%
ine
)
(50
Gu
%)
ani
din
eH
Hyd
CI
rog
(6M
en
)
per
Ph
osp
oxi
de
hat
(10
eb
Sod
%)
uff
ium
er
azi
Sod
de
(1%
ium
)
chl
Sod
ori
d
ium
e(
5%
deo
, 50
Sod
xyc
C)
ium
hol
ate
dod
Sod
(5%
ecy
ium
)
l su
hyp
lfa
te
Sod
och
(
0.0
ium
lor
1M
ite
hyp
)
(0.
Sod
och
0
5%
ium
lor
)
ite
nit
(0.
rat
Ter
1%
e
g-a
)
-zy
m
Tri
◆
e
sb
(
1
uff
%)
er
Ult
(1M
ras
)
il 1
1(
Ure
2%
a(
)
6M
)
Ac
etic
aci
d(
Cit
10%
ric
aci
)
d
For
(1%
mic
)
aci
d(
Hyd
1N
roc
)
hlo
ric
Lac
aci
tic
d(
aci
1N
d(
Nit
) (0
5%
ric
.1N
)
aci
, 50
d
Ox
(
ºC)
1
%
alic
)
aci
d(
Ph
1%
osp
)
hor
ic a
Su
cid
lfu
ric
(1N
aci
) (0
Bu
d(
.1N
tan
1N
, 25
ol (
)
70%
ºC)
Bu
tyl
)
cel
los
Eth
olv
ano
e(
10%
l (7
0%
)
Iso
)
pr o
pan
ol (
Me
25%
rca
pto
)
e
tha
Me
tha
nol
nol
(10
%)
(70
Pro
%)
pan
(
25%
ol (
70%
Am
)
mo
)
niu
m
Sod
hyd
ium
rox
ide
hyd
Iso
rox
(1
pr o
N)
i
d
e(
pyl
1N
ace
Eth
)
t
yl a
ate
cet
(1%
ate
Eth
)
(10
yl a
%
cet
)
ate
Gly
(10
cer
0%
ol
)
Pol
yet
hyl
ene
Ch
gly
lor
ofo
col
r
(0.
m
Ch
1%
(0.
lor
8
)
%)
ofo
rm
(10
0%
)
Centrifugal and TFF Devices
Miscellaneous
Ketones
Centrifugal Devices
Nanosep® Device
Microsep™ Advance Device
Macrosep® Advance Device
Jumbosep™ Device
R
R
R
R
-
R
R
R
R
R
R
R
R
-
-
-
R
R
R
R
R
R
R
R
R
R
R
R
R
R
R
R
R
R
R
R
-
-
R
R
R
R
R
R
R
R
R
R
R
R
R
R
R
R
-
N
N
N
N
N
N
R
R
R
R
R
R
R
R
R
R
R
R
N
-
R
R
R
R
R
R
R
R
-
R
R
R
R
-
-
R
R
R
R
-
-
R
R
R
R
N
N
-
R
R
R
R
N
N
-
-
R
R
R
R
-
-
R
R
R
R
R
R
R
R
R
R
R
R
-
-
-
R
R
R
R
R
R
R
R
N
R
R
R
-
R
R
R
R
R
-
R
-
R
-
R
R
R
R
R
R
R
R
-
R
-
R
R
R
R
R
R
R
-
R
N
-
R
R
R
R
N
R
R
-
R
R
-
R
R
R
-
R
-
R
R
-
R
-
R
N
R
-
R
N
R
-
R
-
R
R
-
R
-
R
R
R
R
R
R
R
-
R
-
R
-
R
R
R
R
-
R
-
R
-
-
-
R
-
-
-
R
-
-
-
-
N
-
-
-
-
-
-
-
-
-
-
-
-
-
R
-
-
-
-
-
-
-
-
-
-
R
-
-
R
R
-
-
-
-
-
R
-
R
R
R
R
R
R
R
-
-
-
R
R
-
-
-
-
R
R
-
-
-
-
R
-
R
-
-
R
R
R
R
-
R
R
-
-
R
-
-
R
R
-
R
R
R
-
-
R
R
R
R
-
R
R
R
R
R
R
R
R
R
R
R
R
R
R
R
R
N
R
-
R
R
R
R
R
R
R
R
R
-
-
R
-
-
-
R
-
R
R
R
-
-
TFF Devices
Minimate™ Device
Ultrasette™ Device
T-Series TFF Cassettes
*HH = Halogenated Hydrocarbons
Cassettes
Centramate™ Cassettes
*AH = Aromatic Hydrocarbons
**HH = Halogenated Hydrocarbons
R
R
R
R
R
R
R
Alcohols
R
R
R
N
R
R
R
R
Bases
R
R
N
N
R
R
Ethers
Esters
R
R
R
N
R
R
R
N
R
AH*
R
HH**
N
R
Ketones
R
R
N
R
Miscellaneous
R
R
R
specific filter under actual use conditions.
Because chemical compatibility is affected
by many variables (including temperature,
pressure, concentration, and purity), various
chemical combinations prevent complete
accuracy.
N
N
R
R
R
R
R
R
R
R
R
R
R
N
R
R
R
R
R
R
R
R
R
R
Compatibility with Omega™ membrane cassettes should
be used only as a guide. Cassettes should be tested in the
appropriate solvent and product under actual operating conditions and for an appropriate time to determine compatibility for
the specific application.
No significant change was observed in flow rate or bubble
point of the membrane. No visible indication of chemical
attack was detected.
L = Limited Resistance
Moderate changes in physical properties or dimensions of the
membrane were observed. The filter may be suitable for short
term, non-critical use. Hardware or housing may be suitable for
short-term exposure at low pressures and ambient temperatures.
N = Not Resistant
APPENDIX
Our ultrafiltration membranes have been
evaluated for compatibility with many
common laboratory buffers and solvents
over a wide pH range.
R
R = Resistant
Alcohol residues that are allowed to dry on a filter may cause
stress cracks. Pall Corporation recommends that filters used
in alcohol processing should remain alcohol wet, or should be
flushed with copious quantities of water to remove residuals
prior to drying and subsequent reuse.
This chart is intended only as a guide.
Accuracy cannot be guaranteed. Users
should verify chemical compatibility with a
296
R
Caution
Test Methods
This data is a compilation of testing by
Pall Corporation with the listed chemicals.
Chemical compatibility was determined with
discs. Flux rates and solute retention was
determined before and after a two-hour
exposure to the indicated chemical. If
membrane integrity was unchanged, the
chemical was deemed compatible.
Membrane integrity for syringe filters
was tested by bubble point.
APPENDIX
R
Eth
ers
Tet
rah
ydr
Tol
uen ofura
n(
5%
Aro e (1%
)
)
ma
tic
Ch
&c
lor
hlo
of
rin
Me orm
ate
(0.
thy
dh
8%
len
ydr
)
Ac
ec
oca
eto
hlo
r bo
ne
rid
ns
(<
e(
Ket
ME
30%
one
K)
)
(1%
Me
)
thy
l et
Ph
eno hyl k
eto
l (0
ne
Ac
(1%
eto .5%)
nit
)
r
ile
Am
(<
mo
40%
niu
Alc
m
chl )
ono
ori
x◆
de
Ca
(
lciu 1%)
(1%
m
)
chl
Dim
o
rid
eth
e(
Dim yl ac
5%
eta
)
eth
mid
y
l
Dim
fo
e
eth rmam (DMA
C)
ide
Dis yl su
(DM (< 4
lf
odi
0%
um oxide
F
)(
)
For
ma salt o (DMS < 40%
lde
O)
fE
)
DT
Glu
(<
hyd
A(
tar
e(
10% 40%)
a
1
Gly ldehy %)
)
cer
de
i
Gu ne (5 (0.5%
ani
0%
)
d
)
Hyd ine H
CI
rog
(6
N-M en pe M)
rox
eth
ide
y
l
Ph
(1%
osp pyrro
)
lido
hat
Sod
eb
ne
uff
(1%
ium
e
r (1
)
az
Sod
ium ide (1 M) (p
H
%
c
8.2
)
Sod
h
)
ium loride
(
d
5%
Sod
e
ium oxych ) (50
ola
ºC)
do
Sod
ium decyl te (5%
sul
)
hy
Sod
ium poch fate (
hyp lorite 0.01
Sod
M
(0.
ium och
005 )
hyp lorite
Sod
%)
o
(
ium
0.0
chl
2%
ori
ni
Ter
te
)
(0.
g-a trate
1%
z
ym
)
Tri
e◆
sb
(1%
u
Tri ffer (
ton
1M )
) (p
X-1
Ure
H8
.
a ( 00 (0
.00 2)
25%
2
Ult
M)
)
ras
il 1
1(
1%
)
chemical compatibility
Acids
Omega™ Membrane
chemical compatibility
Ac
etic
Ac acid
etic
(5%
)
Cit acid
(25
ric
.5%
aci
d
For
)
mic (1%)
a
c
Hyd
id
(5%
roc
Hyd hloric )
roc
aci
Hyd hloric d (0.
1N
roc
aci
at
25
Lac hloric d (0.
ºC
1
tic
Na
aci
a
t5 )
d(
cid
Nit
0º
1
Na
(5%
ric
C)
t5
aci
)
0º
d(
Ox
C)
alic
<1
%)
Ph acid
osp
(1%
hor
)
Su
lfu ic ac
id
ric
(1
a
Bu
tan cid (1 N)
ol (
%)
70%
Bu
tyl
)
c
Eth ellos
olv
ano
e
Iso l (70% (10%
pr o
)
)
pyl
Me
rca alcoh
o
pto
Me
eth l (25%
thy
ano
l al
l (0 )
Am
c
.1%
ine ohol
)
(25
s
Am
%)
mo
niu
Sod
m
hyd
ium
r
h
Sod
ydr oxide
oxi
ium
(5%
de
h
)
Sod
y
(0.
1N
ium droxi
a
d
t
e
hy
25
Sod
(0.
ºC)
1N
ium droxi
hyd de (0 at 50
Sod
.5N
ºC)
ium roxi
at
de
h
25
Ali
ph ydrox (1N a
ºC)
ati
t2
c & ide (
5º
Bu
1N
C)
aro
tyl
at
a
ma
50
t
Eth cetat
e ( ic est ºC)
yl a
4
ers
0
c
%
e
Iso
t
pro ate (< )
pyl
ace 30%)
tat
e(
1%
)
Ultrafiltration Membrane
The membrane or housing is basically unstable and is not
recommended for use.
- = Insufficient Data
Information is not available. Trial testing is recommended.
1.800.521.1520 (USA and Canada)
(+)800.PALL.LIFE (Outside USA and Canada)
www.pall.com/lab
297