After The Genome: A Language for Our Biotechnology Future Opening Remarks James A. Herrick April 12, 2013 Biotechnologies are changing not just the way we experience life, but how we understand ourselves. In response, new paradigms now situate us in somewhat more ambiguous arrangements with our innovations than in the past: as co-existent with our machines, as augmented by our pharmaceuticals, as shaped by our devices, perhaps even as subject to our discoveries. It thus comes as no surprise that we are involved in a broad cultural debate over perhaps the most basic question imaginable—What does it mean to be human in a biotechnological age? We are here at Wake Forest University to explore the intersection of biotechnology, ethics, religion, rhetoric and language itself. There are perhaps no more pressing and consequential concerns being addressed by any group. This national forum provides a location for leading scholars from a variety of disciplines to discuss the vital topics of how language shapes competing visions of our biotechnological future, how our talk affects the reception of biotechnologies in the public sphere, how the growing moral implications of biotechnology demand robust new ethical perspectives, and how a new scientific order of things impinges on venerable religious ideas. Even if your only source of information was the popular press, it would be clear that important developments were taking place in biotech circles. You might even discern that we are in the midst of a technological revolution the likes of which the human race has never witnessed, one that is ushering in enormous changes in social and private life. A team at Duke University under the direction of Miguel Nicoleli recently connected the brains of two rats so as to allow an untrained rat to learn from the experience of a trained rat thousands of miles away via signals transmitted directly to its brain over the Internet. Nicoleli confidently affirmed that such an arrangement could be adapted to human applications. President Obama recently announced plans to map the entire circuitry of the brain, perhaps an American answer to the enormous Human Brain Project recently launched by the European Union under the direction of Henry Markram. Just yesterday researchers announced a technique for rendering the brain transparent, a breakthrough that some thing will revolutionize the study of brain diseases. In October researchers under the direction of Shoukhrat Mitalipov at the Oregon Health and Science University succeeded in repairing defects in germ line mitochondrial DNA in a human embryo. Just last week news sources reported 3D printing of synthetic tissue at Oxford University, a development that might be used to restore or replace damaged organs. Here at Wake Forest University Medical Center, cutting edge research under the direction of Dr. Anthony Atala in the exciting field of regenerative medicine is producing remarkable therapeutic results that are shaping the future of organ transplant procedures. We will be hearing more about these remarkable developments this morning. While today’s biotechnological research is full of promise for widespread benefit, some developments also raise major ethical questions that will require vigorous public debate. These questions include the implications of genetic engineering for our understanding of human nature, the impacts of advanced medical procedures on diverse human communities, and the just distribution of life-saving and capacity-restoring technologies. Robust ethical systems are essential in the context of such sweeping change, systems sufficiently grounded as to provide reliable moral guidance on hugely consequential issues, yet sufficiently adaptable as to ensure meaningful response in the face of rapid technological advances. And, any truly adequate ethic of the biotechnological future will have to attend to the nuances of the emerging languages that are shaping public discussion of biotechnologies. Embedded in the question of biotech language are concerns such as public comprehension and reception of the new technologies, the moral valences of terminology deployed in the public sphere, the persuasive force of rhetorical resources such as narratives and metaphors, and the linguistic nuances of documents that ground important medical decisions. Rhetorical scholar John Lyne has noted that “the discourses of science have substantial impact on thought, action and culture in our time.” And yet, we often are aware of a great chasm between the language of the laboratory and discourse in the public arena. Susan Wells has written of the languages of science that “no other discursive formation is so relentlessly inaccessible to the public, so exclusively addressed to practitioners of scientific disciplines.” In response to a 2009 Gallup Poll only 55% of adult Americans could correctly associate the name Charles Darwin with the term evolution, or any other term, for that matter. Here is another challenge at the intersection of science, language and the public sphere—improving public awareness and understanding of science. But, the issues associated with language about technology are even more complex than we might assume, for language is not a morally neutral tool, a fact as true of the language of biotechnology as of other kinds of discourse. Implicit in its metaphors and metonyms, its narratives and tropes, are ethical imperatives, moral preferences, and selective perceptions. Psychologist Rom Harre wrote in 1986 that “Metaphor and simile are the characteristic tropes of scientific thought, not formal validity or argument,” while cybernetics pioneer Norbert Wiener added the cautionary note that, “The price of metaphor is eternal vigilance.” This is not a new insight. Two hundred years ago physicist Christoph Georg Licntenberg said, “A good metaphor is something even the police should keep an eye on.” Maybe just such a policing action is what philosopher of science Susan Oyama had in mind in taking Richard Dawkins to task for anthropomorphizing DNA in his monumental work, The Selfish Gene. Moreover, language itself evolves; terms emerge and mutate as we craft a language adequate to describe the biotechnological future. Thus economist Robert Fogel has written of “techno-physio evolution,” journalist Joel Garreau of “radical evolution,” philosopher John Harris of “enhanced evolution,” and so on. When we speak of the language of a biotechnology future, we must imagine a large number of stakeholders operating in a wide range of arenas, each employing language strategically to capture public attention, shape interpretation and expectation, promote new technologies, order research agendas, and influence legislation. We also face the challenge of creating forums for citizen response to the constantly changing biotechnology scene, and such forums will demand a comprehensible public language of biotechnology. Finally, in recent decades science and religion have often been understood as rival explanatory systems. As recently as 1997 Stephen J. Gould’s could employ the strategically diplomatic phrase, “nonoverlapping magisteria” to describe their relationship, or lack thereof. More recently, however, we have witnessed something of a linguistic blurring of the line between the two titanic systems of science and technology on the one hand, and religion and spirituality on the other. Some scientific writing has taken on the tone and even the vocabulary of religious discourse: machines can be “spiritual” according to inventor Ray Kurzweil, biotechnology miraculous according to filmmaker Jim Gilliam, carefully managed genetic research might lead us back to Eden according to biologist Lee M. Silver. Tech guru and critic Jaron Lanier writing in a New York Times piece entitled “The First Church of Robotics,” argues that technology is increasingly treated in technology circles as possessing transcendent, even redemptive qualities. And, biotechnology and religion may be more intricately intertwined than even these examples suggest. As the biotechnologies of the next fifty years emerge and develop, as they shape our lives and even our views of ourselves, the themes of this conference will need to be central considerations if our powerful biotechnologies are to develop humanely and be distributed justly.