The Nervous System Lucas Greb, Anuja Mehta, Will Cooper, Shreya Krishnan, Jeet Kothari Function of the Nervous System The nervous system consists of the brain, spinal cord, and nerves (neurons). It is responsible for connecting all the body parts and allowing for communication. Pathway of a Nerve Signal Neurons Neurons are the basis of the nervous system When linked together, they become capable of performing complex processes such as thought and understanding For the nervous system to be functioning, neurons need to be functioning Neurons Structures: Axon: long-stem that extends to dendrite of another neuron Axon hillock: where the axon meets the cell body Dendrite: receiving node of the neuron Cell body/soma: neurons need to live too Synapse: where the axon meets the dendrite Synaptic Cleft: the gap between Glia: non-neuronal cells that help the neurons maintain homeostasis Neurons Neurons Neural Communication: Synaptic cleft is where all the action takes place Movement of ions cause the neuron to fire Positive ions increase the chance of firing and negative ions decrease the chance of firing Agonists vs Antagonists Agonists act positively Antagonists act negatively Neurotransmitters Neurotransmitters deliver the signal Specific neurotransmitters deliver different signals such as dopamine for excitement and melatonin for drowsiness Reuptake takes the neurotransmitter back The neurotransmitters are reabsorbed into the neuron after they are fired and deliver the signal. Divisions of the Nervous System Central Nervous System (CNS) The main “trunk” of the nervous system Composed of the brain and the spinal cord Transmits signals to the rest of the body decides how the body will react to stimuli Protected by the cranium (brain) and by the vertebrae of the spinal column (spinal Peripheral Nervous System (PNS) Nerves that carry information in and out of the central nervous system Sends messages to the CNS (sensory neurons) Acts based on the feedback from the CNS (motor neurons) Connects the CNS to the rest of the body Not protected by bones Somatic Nervous System Controls the body’s skeletal muscles Controls voluntary movement Walking Waving Autonomic Nervous System Controls the glands, organs, and other muscles In charge of involuntary actions Breathing Blood circulation (heart) Releasing hormones Divided into the Sympathetic Nervous System Sympathetic Nervous System Arouses the body Provides energy in stressful situations Fight Flight Fear Intercourse Parasympathetic Nervous System Calms the body Conserves its energy in non-stressful situations Rest Digest Structures of the Brain Brain Stem Medulla: the base of the brainstem that controls heartbeat and breathing. Reticular Formation- the nerve network that plays an important in controlling arousal Thalamus- the brain’s sensory switchboard, located on top of the brainstem. It directs messages to the sensory areas in the cortex and transmits replies to cerebellum and medulla. Cerebellum The cerebellum is attached to the rear of the brainstem. It helps coordinate voluntary movements and balance. Limbic System The Limbic System is a doughnut- shaped system at the border of the brainstem and cerebrum, associated with emotions like fear and aggression. It includes the hippocampus, amygdala, and hypothalamus Amygdala The Amygdala consists of two neural clusters linked to the emotions of fear and anger. Hypothalamus Lies below the thalamus Directs maintenance activities: drinking, body temperature, control of emotions Governs endocrine system Cerebral Cortex Covers the cerebral hemisphere (the outer layer) Made up of interconnected neural cells Ultimate control and info processing center Outer, dark purple layer is the cerebral cortex Hemispheres of the Brain Left Hemisphere: Right Hemisphere: Processes reading, math, science, etc. Recognition Comprehension skills Processes patterns Analytic thought and logic Responsible for nonverbal thinking Detailed Thoughts Sequential Feelings Daydreams Corpus Callosum These are neural fibers that connect the two hemispheres of the brain and allow for communication When cut, functions of the hemispheres are impaired Lobes of the Brain Frontal: speaking and muscle movements, as well as making plans and judgements, short term memory Occipital: includes visual and perception areas Parietal: receives sensory input for touch and body position Temporal: includes auditory areas, long term memory, Lobes of the Brain Diseases of the Brain Diseases Multiple sclerosis - myelin sheath around some axons in the CNS becomes damaged, causing conduction to slow or even stop, with symptoms such as visual disturbances, muscle weakness, trouble with coordination and balance, and thinking/memory problems Alzheimer’s disease - type of dementia that causes problems with memory, thinking, and behavior based on the extent of the disease (mild, moderate, severe) Parkinson’s disease - progressive disease characterized by loss of neurons in particular locations, resulting in imbalance, rigidity, and slowed movement Diseases Epilepsy - recurrent seizures as a result of any trauma to brain causing brain to be excitable or irritable; seizures depend on part of the brain that is affected Stroke - blood clot travels to the brain causing flow to either slow or stop completely with symptoms such as numbness on one side of the body, trouble speaking, trouble seeing in both eyes, or loss of balance Meningitis - infection of membranes covering brain and spinal cord, centered in the cerebrospinal fluid that surrounds the nervous system with symptoms such as fever/chills, nausea/vomiting, severe headache, sensitivity to light, and mental status changes Diseases Diseases Quiz 1. What are the two divisions of the autonomic nervous system and what are their functions? 2. What is the function of the cerebellum? 3. What is the function of a nerve? 4. What does the somatic nervous system do? 5. What are the three components of the brain stem? 6. What neurologic disease is characterized by loss of neurons, resulting in issues in movement? 7. What is the function of the corpus callosum? 8. What are neurotransmitters?