Sexual Reproduction MEIOSIS MEIOSIS •The production of sex cells (gametes) •Male gamete (sperm), Female gamete (egg/ovum) •2 Stage cell division in which the chromosome number is reduced by one half MEIOSIS •A human cell normally contains 46 chromosomes. This number is referred to as the diploid chromosome number (2n) •When the same human cell undergoes meiosis, it produces sex cells (gametes) that have 23 chromosomes •This number is referred to as haploid (half) and is given the symbol “n” 23 chromosomes male gamete (sperm) 23 chromosomes female gamete (egg) 46 chromosome zygote To summarize: Meiosis Mitosis 2n 2n 46 2n 46 n 46 n 23 46 23 23 23 23 23 MEIOSIS Involves 2 cell divisions that produce 4 haploid cells Meiosis I = “reduction division” and “genetic recombination” Meiosis II = separation of 2 chromatids (maintains haploid number) Stages of Meiosis Meiosis I Prophase I tetrad •Nuclear membrane dissolves •Centrioles move to opposite poles •Spindle fibres appear •Chromosomes come together as homologous chromosomes (4 chromatids called a tetrad) •Aligning of homologous chromosomes is called synapsis •Chromatids often intertwine and exchange segments (crossing over a.k.a. genetic recombination) Causes diversity Stages of Meiosis Meiosis I Metaphase I •Homologous pairs attach to the spindle fibres and line up at the equatorial plate (middle of cell) Stages of Meiosis Meiosis I Anaphase I •Homologous chromosomes move to opposite poles •Each side gets only 23 chromosomes Stages of Meiosis Meiosis I Telophase I •Cytoplasm divides forming two cells •Each new cell is now haploid •Nuclear membrane reappears Stages of Meiosis Meiosis II - similar to Mitosis..only without DNA replication Prophase II •Nuclear membrane dissolves •Spindle fibres begin to form Stages of Meiosis Meiosis II - similar to Mitosis..only without DNA replication Metaphase II •Chromosomes line up along the equatorial plate Stages of Meiosis Meiosis II - similar to Mitosis..only without DNA replication Anaphase II •Chromatids move to opposite poles Stages of Meiosis Meiosis II - similar to Mitosis..only without DNA replication Telophase II •Cytoplasm divides and nuclear membrane appears •Meiotic division is complete with four daughter cells each with 23 chromosomes Meiosis is important because... It allows for sexual reproduction It allows for greater range of characteristics It ensures (via sexual reproduction) the recombination of genes Summary: Genetics Videos Genetics 101 Part 1, Part 3 Homework Complete Mitosis/Meiosis worksheet Read pages 169-172 #7, 8, 10-12 (page 172)