Cell Structure and Function Chapter 3 I. Cell Theory A. Discovery of Cells 1. Robert Hooke (1665) a. first to identify cells by looking at slices of cork under a microscope b. Hooke named cells, he thought they looked like the rooms (cells) monks lived in 2. Anton van Leeuwenhoek (1674) - made a better microscope, one of the first to describe living cells he observed swimming in a drop of pond water B. Development of the Cell Theory 1. Matthias Schleiden (1838) – first to note that plants are made of cells 2. Theodor Schwann (1839) – first to note that animals are made of cells, concluded that all living things are made of cells 3. Rudolf Virchow (1855) – reported all cells come from preexisting cells 4. Cell Theory (three parts) a. all organisms are made of cells b. all existing cells are produced by other living cells c. the cell is the most basic unit of life C. Prokaryotic cells and eukaryotic cells 1. Prokaryotic cells do not have a nucleus or other membrane bound organelles Examples - bacteria 2. Eukaryotic cells have a nucleus and other membranebound organelles Examples: Animals, plants, fungus, protist II. Cell Organelles – structures specialized to perform distinct processes within a cell A. Cells have an internal structure 1. Cytoskeleton – network of proteins, such as microtubules and microfilaments inside a eukaryotic cell a. Microtubules – long hollow tubes, give cell shape and act as tracks for the movement of organelles b. Microfilaments – tiny threads that enable cells to move and divide 2. Cytoplasm – jellylike substance inside cells that contains molecules, helps cells maintain shape B. Organelles involved in making and processing proteins 1. Nucleus – storehouse for genetic information (DNA) 2. Nuclear Envelope – double membrane that encloses the nucleus 3. Endoplasmic reticulum (ER) – interconnected network of thin folded membranes that produce, process and distribute proteins a. smooth ER – lacks ribosomes b. rough ER – studded with ribosomes 4. Ribosomes – tiny organelles that link amino acids together to form proteins (site of protein synthesis) 5. Golgi Apparatus – closely layered stacks of membrane-enclosed spaces that process, sort, packages, and deliver proteins 6. Vesicles – small organelle that contains and transports materials within the cytoplasm C. Other Organelles 1. Mitochondria – Supply energy to the cell, bean shaped and have two membranes, inner membrane has many folds that increases surface area 2. Vacuole – fluid-filled sack used for storage of materials needed by the cell a. animal cells usually have many small vacuoles b. plant cells have a single, large vacuole 3. lysosomes – membrane-bound organelle that contains enzymes, defends cell from invading bacteria and viruses, they also break down damaged or worn-out cell parts 4. centrosome – small region of cytoplasm that produces microtubules 5. centriole – small cylinder-shaped organelle in animal cells D. Plant cells have cell walls and chloroplast 1. Cell walls - rigid layer that surrounds the cell membrane, gives protection, support, and shape to the cell, found in plants, algae, fungi, and most bacteria, the cell wall is made primarily of cellulose 2. Chloroplasts – organelle that carries out photosynthesis III. Cell Membrane A. Cell Membranes are composed of two phospholipids layers 1. Cell membrane (Plasma membrane) a. forms a boundary between a cell and the outside environment b. controls the passage of material into and out of a cell 2. Phospholipid molecules make up the cell membrane a. Three parts to each phospholipids 1) a charged phosphate head 2) a glycerol 3) two fatty acid chains b. the phosphate head and the glycerol form a polar head (hydrophilic) c. the fatty acids form the nonpolar tails (hydrophobic) 3. Cholesterol molecules strengthen the cell membrane 4. proteins extend through the phospholipids layers and help materials across the membrane B. Fluid Mosaic Model – describes the arrangement of molecules that make up the membrane (see page 82) C. Selective permeability (semipermiable) – allows some, but not all, materials to cross D. Chemical signals are transmitted across the cell membrane 1. receptor – a protein that detects a signal molecule and performs an action in response 2. intracellular receptor – within the cell 3. Membrane Receptor – located within the cell membrane IV. Diffusion and Osmosis A. Passive Transport – movement of molecules across a cell membrane without energy input from the cell 1. Diffusion – movement of molecules from a region of higher concentration to a region of lower concentration a. Concentration gradient – difference in the concentration of a substance from one location to another b. Molecules diffuse down their concentration gradient (from high to low concentration) c. Example – oxygen easily diffuses into a cell without the cell expending energy 2. Osmosis – the movement of water molecules across a semipermeable membrane from an area of high concentration to an area of low concentration a. Isotonic solution (iso = same) – a solution has the same concentration of dissolved particles as the cell b. Hypertonic solution (hyper = higher) – a solution has a higher concentration of dissolved particles than a cell c. Hypotonic solution (hypo = lower) a solution has a lower concentration of dissolved particles than a cell 3. Facilitated diffusion – the diffusion of molecules across a membrane through transport proteins (passive transport) V. Active Transport – movement of molecules across a membrane from an area of low concentration to an area of high concentration, requires an input of energy A. Proteins can transport materials against the concentration gradient B. Active transport with vesicles 1. Endocytosis – uptake of liquids or large molecules into a cell by inward folding of the cell membrane 2. Phagocytosis - uptake of a solid particle into a cell by engulfing the particle 3. Exocytosis – release of substances out of a cell by the fusion of a vesicle with the membrane 4. Process when a cell engulfs a liquid (cell drinking)