Anatomy of the Central Nervous System Divisions of the Mammalian Nervous System Central Nervous System = the brain and the spinal cord Peripheral Nervous System = the nerves outside the brain and spinal cord Two Divisions of the PNS Somatic Nervous System - the nerves that convey messages from the sense organs to and from the CNS Autonomic Nervous System - a set of neurons that control the heart, the intestines, and other organs Nervous System PNS SNS CNS ANS sympathetic Brain parasympathetic Spinal Cord The Nervous System The Spinal Cord-part of the CNS found within the spinal column The spinal cord communicates with the sense organs and muscles below the level of the head Bell-Magendie Law-the entering dorsal roots carry sensory information …and the exiting ventral roots carry motor information to the muscles and glands Dorsal Root Ganglia - are clusters of neurons outside the spinal cord Figure 4.3 Diagram of a cross section through the spinal cord The dorsal root on each side conveys sensory information to the spinal cord; the Autonomic Nervous System Sympathetic - prepares the Parasympathetic - facilitates vegetative, non-emergency body for activity responses by the body’s organs Increased breathing, Increase digestive activity, and heart rate, activities opposing decreased digestive sympathetic system activity Consists of cranial nerves and Form chain of ganglia nerves from sacral spinal cord just outside spinal cord Long preganglionic axons extend from the spinal cord to Short preganglionic parasympathetic ganglia axons release close to each internal organ; norepinephrine release norepinephrine Long postganglionic Shorter postganglionic fibers axons release then extend from the norepinephrine parasympathetic ganglia in the organs; release acetylcholine The Mammalian Brain There are 4 main parts to the brain: 1. Hindbrain (cerebellum + medulla oblongata) 2. Midbrain 3. Diencephalon ( thalamus + hypothalamus) 4. Forebrain (cerebral hemispheres) The Brain The Hindbrain ( Posterior part of brain ) Medulla Oblongata - controls vital reflexes like breathing, heart beat Blood pressure (all via sympathetic and parasympathetic n.s.) Cerebellum – controls movement, shifts of attention, balance and coordination. Works by comparing intended with actual movement. Medulla oblongata Para-sympathetic slows down Sympathetic speeds up Sino Atrial Node (SAN) The Brain The Midbrain - middle of the brain Connects fore and hind brains. Mainly responsible for movements such as head and eyes focussing on an object. The diencephalon Thalamus Centre of forebrain Relay Station for sensory information (‘switchboard’) Hypothalamus Regulates homeostasis, sexual behavior, fighting, feeding Pituitary Gland Endocrine gland attached to the base of the hypothalamus (ADH, GH, FSH, TSH) The Brain The Forebrain - most anterior and most prominent part of the mammalian brain, comprising the… Cerebrum (left and right cerebral hemispheres) Figure 4.12 A sagittal section through the human brain The Cerebrum The cerebral hemispheres contain 109 nerve cells in a layer only 3mm thick. Left and Right hemispheres are linked by the CORPUS CALLOSUM. Each hemisphere has 4 LOBES: i) Frontal ii) Parietal iii) Temporal iv) Occipital Frontal Lobe The Frontal Lobe-extends from the central sulcus (groove) to the anterior limit of the brain Contains Primary Motor Cortex – responsible for fine movements Contributes to shifting attention, planning of action, delayed response tasks as examples Parietal Lobe The Parietal Lobe - between occipital lobe and the central sulcus Contains the primary somato-sensory cortex – i.e. receiving touch sensation, muscle-stretch information and joint position information Also, 3-D processing (visualisations, face recognition etc) Temporal Lobe The Temporal Lobe - lateral portion of each hemisphere, near the temples Contains targets for hearing, essential for understanding spoken language (Wernicke’s Area), complex visual processes, emotional and motivational behaviors Occipital Lobe The Occipital Lobe - posterior end of cortex Contains primary visual cortex Figure 4.20 Some major subdivisions of the human cerebral cortex The four lobes: occipital, parietal, temporal, and frontal. Which part of the brain contains: The cerebrum? Forebrain The cerebellum? Hindbrain The medulla oblongata? Hindbrain Pituitary gland? Diencephalon. Which lobe of the cerebrum deals with: a) b) c) d) e) memory vision language hearing spatial awareness Essay for next week: a) Outline the functions of the cerebrum in the human brain. b) Describe the changes that occur in the cerebrum of a person with Alzheimer’s disease and discuss the possible causes of the disease. Try a web search eg www.alz.org or www.alzheimers.org