PP 02Gross anatomy, terms of direction, and sections/planes Two Major Divisions of Nervous System (NS) • CNS: Brain & Spinal Cord – Protection by bony shell, • meninges, & CSF PNS: Sensorimotor (Spinal/Cranial) Nerves: Innervation of organs, muscles, joints, & skin – Somatic nervous system – Autonomic nervous system (ANS) • Sympathetic and parasympathetic systems CNS levels • Cerebrum – incl. basal ganglia, limbic system • Diencephalon (thalamus and hypothalamus) • Brainstem – Midbrain, pons, medulla • Cerebellum • Spinal cord Terms of Direction: Overview Terms of direction denote relative position of one neurological structure to another • Two systems of “higher, lower, more forward, more backward”: – System referenced to person standing in 3-D space • Superior / inferior ; anterior / posterior – System referenced to anatomical neuraxis, which is straight in many animals, and curved in humans. • Rostral / caudal; ventral / dorsal • A system of “closer to the midline, farther from the midline” • Medial / lateral • A system of “how close to the point of connection with the body” • Proximal / distal First system of “higher, lower, more forward, more backward” – System referenced to human in anatomical position in 3D space •Superior / inferior ; anterior / posterior Human anatomical position = Posterior Superior Anterior Inferior Body erect, hands at side, palms facing outward 6- Superior 2- Inferior 1- Anterior 5- Posterior When referring to structures of the head as superior to other structures, the terms cranial or cephalic are sometimes used as terms of direction First system of “higher, lower, more forward, more backward” Examples: • The brain is superior to the spinal cord • The brain is cephalic to the spinal cord • The brain is cranial to the spinal cord • The spinal cord is inferior to the brain • The brain stem is anterior to the cerebellum • The cerebellum is posterior to the brain stem Second system of “higher, lower, more forward, more backward” System The human anatomical neuraxis starts as a referenced to straight tube (called the neural tube). During development it bends/curves almost anatomical 90 degrees at the juncture of the brainstem neuraxis, which and diencephalon is straight in many animals, and curved in humans. rostral/ caudal; ventral / dorsal Human anatomical neuraxis = brain and spinal cord 1- early human embryo neurological system, straight like the salamander’s 2- human embryo neurological system- 3 weeks; curved neuraxis! 3-mature human; major curve remains near juncture of brainstem and diencephalon; neuraxis “mushrooms out” around curve Second system of “higher, lower, more forward, more backward” Examples: • The front part of the cerebrum is rostral to the spinal cord • The spinal cord is caudal to the front part of the cerebrum • The brain stem is ventral to the cerebellum; the lower part of the cerebrum is ventral to the upper part of the cerebrum • The cerebellum is dorsal to the brainstem; the upper part of the cerebral is dorsal to the lower part of the cerebrum Compare the two systems of “higher, lower, more forward, more backward” The neuraxis bends around the junction between the midbrain and diencephalon, so…. – At the level of the spinal cord and brainstem • Anterior=ventral • Posterior=dorsal • Superior=rostral • Inferior=caudal – At the level of the diencephalon and the telencephalon • Inferior=ventral • Superior=dorsal Posterior Anterior Rostral Superior Inferior System of “closer to the midline, farther from the midline” Anterior view of brain Medial/ lateral Lateral view of brain lateral medial Medial view of brain lateral System of “how close to the point of connection with the body” Proximal= nearer to the point where the structure connects to the body vs. Distal = farther from the point where the structure connects to the body Posterior Superior Anterior Inferior Example: The shoulder is more proximal to the body than the fingers. The fingers are more distal from the body than the shoulder. Shoulders more proximal, fingers more distal…… Limb Movement Terms • Flexion • Extension • Abduction • Adduction • Pronation • Supination Sections/Planes: A cut through the body, or a part of it, is called a section; the resulting cut surface is called a plane Sections/Planes • First system based on slices through 3-D space – Horizontal section/plane (A) – Coronal section/plane (B) – Sagittal section/plane (C) Posterior Superior Anterior A C B Inferior Sections/Planes: First System (Continued) A. Horizontal B. Coronal (when anterior, also called frontal) C. Midsagittal (also called medial) C. Parasagittal Sections/Planes: Second system • Second system based on slices at right angles to longitudinal axis of the structure – Transverse or cross section/plane Remember that the longitudinal neuraxis is curved Compare the two systems of sections/planes The neuraxis bends around the junction between the midbrain and diencephalon, so…. – At the level of the spinal cord and lower brainstem • Horizontal=transverse – Near the bend (upper brainstem and diencephalon) • Transverse has no analog in the 3-D system of sections/planes – Rostral to the diencephalon • Coronal = transverse and is also called a frontal section/plane Anatomic vs. clinical orientation (from readings) • Compare the two. See especially pp. 24 and 25 (Figure 1-9)