Charcot-Marie-Tooth Disease
By Will Hurd and Richie Excell
http://publications.nigms.nih.gov
/biobeat/07-07-18/index.html
Links
DNA and Amino
Acid Sequences
Details
Citations
Conclusion
Charcot-Marie-Tooth Disease is a disease where the
nervous system can’t communicate with itself. Therefore it
shows the symptoms of feeling no pain or temperature
(because of no sensory nerves) and then not being able to
move muscles in the lower body then later in the whole body
(because of motor nerves). Onset of symptoms is most often
in adolescence or early adulthood, but some individuals
develop symptoms in mid-adulthood. This disease is
autosomal dominant and located 19p13.2. CMT originally got
its name from the 3 scientists who discovered it in 1866, JeanMartin Charcot and Pierre Marie in Paris, France, and Howard
Henry Tooth in Cambridge. It also is the most common
neurological disorder in the United States, affecting
approximately 1 in every 2500 people. There is no cure for
CMT, however physical therapy as well as orthopedic exercises
and sometimes every surgery can help people cope with the
symptoms of the disease. The prognosis for CMT is most
certainly not fatal. In fact, most people with this disease life a
normal life expectancy. It is a very interesting disease to learn
about, especially behind the complicated process of how it
develops.
http://www.ninds.nih.gov/disorders/charcot_marie_tooth/det
ail_charcot_marie_tooth.htm
http://publications.nigms.nih.gov/biobeat/07-0718/index.html