GENE EXPRESSION Pretty Please Big Brother Back door GENE EXPRESSION Target: I will be able to explain how DNA and genes result in the expression of traits and how genes turn on/off. Gene Expression: Process by which information from a gene is used to make a functional gene product (Proteins, tRNA, and rRNA). The type of cell that is made is determined by the genes that are expressed. Pg. 95 Regulatory Proteins: Proteins that bind to the DNA to control transcription. They act as gene switches to turn on or off the genes. Negative Control: Transcription is controlled because the protein interferes with (stops) transcription Positive Control: Transcription is controlled because the protein enhances (helps) transcription All cells contain the same DNA and Genes •Depending on what genes are turned on or off, will determine what cell it is and how it functions. Cell Differentiation: the genes that are turned on (or transcribed), results in different proteins being made (or translated), which makes the cell what it is. Hox Genes: Master control genes. They control the order and location where cells, tissues and organs develop in an organism If Hox Genes do not turn on in the right order, then body parts may develop in the wrong place. All cells contain the same DNA and Genes •Depending on what genes are turned on or off, will determine what cell it is and how it functions. Cell Differentiation: the genes that are turned on (or transcribed), results in different proteins being made (or translated), which makes the cell what it is. Hox Genes: Master control genes. They control the order and location where cells, tissues and organs develop in an organism If Hox Genes do not turn on in the right order, then body parts may develop in the wrong place. Summary TURNING GENES ON AND OFF Draw a picture to represent positive control of gene expression. • Write a sentence explaining how the picture relates to positive control. Draw a picture to represent negative control of gene expression. • Write a sentence explaining how the picture relates to negative control. Draw what a Hox Gene does, or what happens when it doesn’t work correctly. Pg. 94