Living Donor Kidney Transplant
Margaret Leid
Transplant Community Liaison
Penn Transplant Institute
margaret.leid@uphs.upenn.edu
April 15, 2012
Greater Philadelphia Region Kidney Transplant Centers
Deceased & Living Donor Transplants: Volume*
* Scientific Registry of Transplant Patients, January 2012.Time period 7/1/2010 – 6/30/2011. www.srtr.org
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Penn Transplant Institute
Highest Volume Center in the Region
Penn Transplant Institute
Best 3-Year Graft Survival in Region
100.00%
200
90.00%
180
80.00%
160
70.00%
140
60.00%
120
50.00%
100
40.00%
80
30.00%
60
20.00%
40
10.00%
20
0.00%
PENN
0
PENN
A
B
A
B
C
C
Penn Transplant Institute
3-Year Patient Survival
100.00%
95.00%
90.00%
85.00%
80.00%
75.00%
PENN
A
B
C
SRTR Data 1/2012. For
patients transplanted
between 1/1/2006 and
3
6/30/2008
Penn Transplant Institute – Kidney Transplant Program
EXPERIENCE
First kidney
transplant
1966
VOLUME
Highest volume in
Philadelphia
Region
OUTCOMES
Best 3-year graft
survival rates in
Philadelphia region*
LIVING DONOR TEAM
One of country’s most
experienced teams.
Most living kidney
donors in region*
GUEST HOUSE
For transplant
patients and their
families traveling
more than 50
miles
EVAL CLINIC
YARDLEY, PA
Reduces travel
time by car from
NYC by one hour
each direction
ACCESSIBLE
By Train
Amtrak, NJ Transit
By Bus
Greyhound
Megabus, Bolt Bus
LOCATION
Historic University of
Pennsylvania Campus
located in
shopping/dining
University City District
*Based on January 2012 SRTR data
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Clyde F. Barker Penn Transplant House
NEW GUESTHOUSE
SUPPORT THROUGH ALL
PHASES OF CARE
CONVENIENT
LOCATION
Evaluation
Surgery
Follow-up
Five blocks from Penn
On Septa bus line
INSURANCE
COVERAGE
KIDNEY TRANSPLANT
SUPPORT GROUPS
LONG TERM STAYS
Considered part of travel
expense for transplant
evaluation and follow-up.
Check with insurance company
Second Sunday of each month.
Pre and post transplant
patients and their families
Light refreshments provided
Built in June 2011
For Penn transplant patients
and families traveling more
than 50 miles
Beautiful common kitchen area
with storage for each family.
Common living and dining area
for connection with other
transplant patients and families.
For Reservations and Additional Information: 215-662-4540
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Questions to Run On
 Why does a kidney from a living donor sometimes last twice
as long as a kidney from a deceased donor?
 How do I know it is safe for my friends or family to donate a
kidney to me?
 How does someone interested in learning about donating a
kidney get information before committing to the surgery?
 What are the health requirements for someone thinking about
donating a kidney?
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How Do Kidneys Become Available?
Deceased Donor Kidneys
Living Kidney Donors
4 to 6 Year Wait
UNITED NETWORK OF ORGAN SHARING (UNOS)
OR
Living Donors
Do Not Need
to Be in Your
Family
DONOR
HOSPITAL
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Where do deceased donor kidneys come from?
TRANSPLANT CENTERS
List patients for transplant
Penn is 1 of 256 transplant
centers in the U.S.
Recipient data
sent to UNOS
computer system
(UNITED NETWORK FOR ORGAN
SHARING)
Government contract to
oversee the national
system for U.S. organ
procurement an
transplantation
ACUTE CARE HOSPITALS
Work with OPOs to coordinate the
organ donation process
One Central Database
Family Says
Yes to
Donation
Transplant Waiting List:
Updated Every Time A Family Says
Yes to Donation and Every Time a
Patient is Added to the List
Donor Data Sent to
UNOS
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OPTN DATA
1/20/2012
http://optn.transplant.hrsa.gov
U.S.TRANSPLANT
WAITING LIST
ALL ORGANS
Our Region
112,637
KIDNEY = 80%
90,621
GIFT OF LIFE DONOR PROGRAM
DONATION YEAR 2009-2010
780
5,335
KIDNEY
TRANSPLANTS
WAITING
AVERAGE WAITING TIME
3–5
YEARS
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91,425 people in U.S. waiting for kidney
An average of 16,000 people receive
kidney transplants per year
Gallup Poll of
Americans
Donor Designation
Pennsylvania
93%
45.2%
Would Donate Their Loved
One’s Organs If They Knew
Their Wishes Ahead of Time
Philadelphia County
30%
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How Many of Your Patients
Understand:
Dialysis shortens life expectancy
compared to transplant.
The less time on dialysis before transplant,
the better the kidney will function and
the longer it will last.
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Optimum Strategies to
Minimize Time On Dialysis
Living Donors
Consider Kidneys from
Expanded Criteria Donors
(ECD)
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Summary of Options
Most life years
 Own healthy kidneys
 Living donor kidney
 Standard criteria kidney
 Expanded criteria kidney
 Dialysis
Fewest life years
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Why does a kidney from a living donor
sometimes last twice as long as a kidney from
a deceased donor?
 Kidney not impacted by brain death.
 The time the kidney is without blood
flow is dramatically reduced.
 Living kidney donors are healthier
than the average person.
 Only very healthy people are accepted
at Penn to be living kidney donors.
 First living donor transplant at Penn
more than 40 years ago. Donor and
recipient still doing well.
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Benefits of Living Kidney Donor Transplantation
 Kidney lasts longer – improved quality
 Avoid dialysis completely or shorten time on dialysis
• Before complications develop
 Improved patient survival
 Avoid 4-6 year wait for deceased donor kidney
 Time of transplant operation is made at convenient
time for donor and recipient
 Minimal delayed organ function
 Medicines post-transplant may be less aggressive
Who can be a living donor?
 Family member
 Friend
 Stranger
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Living Donor Evaluation Process
Extensive and Thorough
DONOR
EDUCATION
SESSION
MULTIDISCIPLINARY
EVALUATION
NEPHROLOGY
EVALUATION
SURGICAL
EVALUATION
DONOR SELECTION
COMMITTEE REVIEW
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Interested in Living Kidney Donation?
Steps for Listed Patients
Steps for Potential Donors
Complete all testing and attain status
1 on the transplant waiting list.
1. Submit request for private
preliminary consultation
with the Living Kidney
Donor team.
Share with your family and friends
your experiences with chronic
kidney disease and dialysis.
1. Invite interested potential donors
to complete the Living Kidney
Donation Referral Form.
2. Encourage friends and family
members to support organ
donation awareness initiatives
through Gift of Life.
2. Learn about the living
kidney donor process
through the evaluation
process
3. Talk with the team about
concerns and questions.
4. Decide if this is the right
option for you at this time.
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What Are the Top 5 Criteria to be a Living Kidney Donor?
Good general health
Between 21 and 60 years old
Physically fit - Body Mass Index
(BMI) <30
Stability in life maintenance issues.
Free from diabetes, cancer, kidney
disease, heart disease and
substantial high blood pressure.
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Paired Kidney Exchange
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How to Find a Living Donor
Share your story about dialysis and needing
a kidney transplant.
- Volunteer organizations
- Religious groups
- Friends and family: consider a spokesperson
Learn about living donor kidney transplant
Penn Transplant Website
http://www.pennmedicine.org/transplant/
American Society of Transplant Surgeons (ASTS)
http://www.a-s-t.org/
National Kidney Foundation - http://www.kidney.org/
American Society of Transplantation
http://www.asts.org/ResearchEducation/PatientEducation.aspx
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How does someone interested in learning
about donating a kidney get information
before committing to the surgery?
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PENN KIDNEY TRANSPLANT : PATIENT & STAFF EDUCATION SERVICES
Patient Education
Dialysis Unit Staff
Lobby Days
Inservices/Luncheons
One to One Sessions
Transplant Eval Process
Intro to Kidney Transplant
Organ Donation Protocols
Multiple Listing
Understanding SRTR Data
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