6th Grade Assignment
 Title Page – Disease and student names
 Introduction – Write last
 2 slides for each student’s disease
5-8
symptoms of the disease
Pictures of people with the disease (nice
pictures)
Treatment of the disease
Which chromosome is involved?
Number of people who have the disease
 Conclusion
– Write second last
7th Grade Assignment
 1st Par –
Who
discovered?
List symptoms
What population,
nationality, or gender
is affected?



Spelling
Complete
Sentences
Varied Sentence
Structure
 2nd
Par –
 How
is it treated?
 What tests are used to diagnose?
 3rd
Par –
 What
chromosome is this disease found on?
 What year was the disease identified and how long until it
was associated with being a genetically transferred disease?
 Discuss any other genetic connections you learned about as
you investigated this disease.
 How many people have this disease?
 Male
= XY sex chromosomes
 Female = XX sex chromosomes
 Father determines the sex of baby.



How?
X or Y in the sperm
½ set of chromosomes has only one sex
chromosome
 Alleles
– different forms of the same gene
 Blood types A, B, AB, O
 Alleles A, B, O
 Controlled by Chromosome 9
 Combinations
Blood
 Blood
 Blood
 Blood

type A
type B
type AB
type O
AO or AA
BB or BO
AB
OO
 If
one parent is blood type A and the other
blood type O what are the possible children
blood types?
 If
a parent is blood type A and the other
parent is blood type B what are the possible
blood types of their children?
 Universal

donor?
No antigens…
 Universal
receiver of
blood?

Have all the different
antigens already in
blood…
 Alters
the shape of the red blood cells
 A = normal allele for red blood cells
 S = sickle cell allele for red blood cells
 AA = normal blood type
 AS = carrier of sickle cell (1/2 of cells are
normal)
 SS = sickle cell disease
 Identical
twins
Same egg and same sperm = same DNA
 Have to be the same sex (two sisters)
 .5 % of total population

 Fraternal


twins
Different egg and different sperm = diff DNA
Same sex or different sex (two brothers or a
brother and sister)
 Traits
that are carried on the
X chromosome
 Can mothers pass traits to sons?
 Can fathers pass traits to sons?
 Can mothers pass traits to daughters?
 Can fathers pass traits to daughters?
 Hemophilia


“bleeder’s disease”
blood clots abnormally slowly or not at all
 Ryan
White died in 1990 from hemophilia,
contracted AIDS from a blood transfusion,
which is necessary for hemophiliacs when
they bleed from injuries often.
 Royal family has a history of hemo… page
68
 QEII does her line have H… in it today?
 Hemophilia
 Colorblindness
– can’t
distinguish between
colors
 Male patterned
baldness





Shows the size, number, and shape of all the chromosomes in an
organism
47 chromosomes
Trisomy 21 - 3 chromosomes in a pair
Down Syndrome
Amniocentesis – test for down syndrome
1
2
3
4
5
Do you support abortion?
Would you abort a Down Syndrome child?
Does the state have the right to force a couple to
abort an unborn handicap child?
Would you want to genetically engineer your child?
Should it be helping people who are very sick to kill
themselves?





Amniocentesis – removal of small amount of fluid from
sac that surrounds the baby (baby cells are in the fluid –
test done between 16-18 weeks
Other tests can be done at 10-12 weeks CVS
No cures for genetic disorders WHY?
1982 – doctors tested a drug that was to change the
cells of Sickle Cell page 71
1989 – identifies gene responsible for cystic fibrosis and
changed the gene in the cell and it became normal???
 1:700
births
 Most common
syndrome
 1866 JL Down
 Flat broad hands
 Flat bridge of nose
 Flat space between
1st and 2nd toe
 Can
we detect genetic disorders?
 Can we cure genetic disorders?
 What do we do if we can’t cure the
disorder?
ABORTION
 TAXPAYERS PAY TO KEEP THESE CHILDREN
 INSURANCE PRICES ???
 SOCIETIES COST ???
 IS THIS SCIENCE OR RELIGION OR MORALS?

 Definition
– the rules a society lives by
 What morals do you live by?
 Make a list of what rules you live by.
 Put
the things that are good on the right.
 Put the things that are wrong on the left.
 Karyotype
 Incomplete
Dominance
 Multiple Alleles
 Sex-Linked Traits
 Pedigree
 Karyotype
- pairing of chromatids
 Nondisjunction

Occurs during meiosis when chromosomes
do not separate properly
 Pedigree
shows members of a family
 Amniocentesis - tests fluid around the
baby for genetic disorders
 Codominant – capital letters for all
alleles
 DNA
molecules= basic substances of heredity
 DNA stores and passes genetic information
 The discovery of DNA was most important
discovery of 20th century
1
2
3
4
5
Name the 4 blood types
How many different alleles are there
for blood type?
Name the two different arrangements
of alleles for blood type A
Name the most uncommon type of
blood
Name a blood type that has two
different antigens.
6.
7.
8.
9.
What do we call a picture that shows all
your relatives and who had a specific
disorder?
What gender are you if you have an XY
chromosome?
Who is the universal donor for blood?
Describe what a sickle cell anemia blood
cell looks like?
10.
11.
12.
13.
14.
Can a sickle cell father pass the disease
on to his son?
Name 3 diseases that are sex-linked
traits.
What does it mean when a trait is a sexlinked trait?
Describe what a sickle cell anemia
blood cell looks like?
What do we call the test that removes
fluid from next to the baby and does a
karyotype?
1.
2.
3.
4.
5.
Read directions
Only father flips for
gender of baby
Record an H or T
depending on the flip
of the coin
Record the genotype
from the key
Record the phenotype
from the key