Drugs 9th grade Health What are drugs? Drugs are substances that are used to treat or prevent diseases. They are also used to relieve pains, to help control mental or physical ailments, and even to help diagnose illnesses. Drug Vocab Tolerance Body becomes accustomed to drug and causes the user to experience a need for more and more drug to achieve the desired effect or high. Psychological Dependence A condition that occurs overtime and causes user to believe that drug is needed in order to feel good or function normally. Drug Vocab Physiological dependence A user develops a chemical need for a drug. Symptoms of withdrawal occure when the effects of the drug wear off. Symptoms can include nervousness, insomnia, headaches, vomiting, chills, and cramps. Addiction A physiological or psychological dependence on a drug. Classification of Drugs Prescription Marijuana and THC Inhalants Steroids Psychoactive “Club Drugs” Stimulants Depressants Marijuana and THC Marijuana is produced from the dried leaves and flowers of the cannabis plant. The active ingredient is THC (tetrahydrocannabinol) A fat-soluble drug Produces psychoactive effects of Marijuana Fat-soluble means that the drug will be distributed to those areas of the body with high fat content. Marijuana and THC THC stays in the body for several weeks Why? Fat soluble areas of the body are: Brain Lungs Reproductive System A person who uses marijuana may be under its effects several days later, even though the "high” has worn off. Marijuana and THC How it’s used Smoked, Ingested or Taken as a Pill It’s used to achieve a state of calmness or euphoria. Almost all users report a change in how they perceive time. Larger doses may produce anxiety and feelings of paranoia. Short term effects When smoked much more THC enters the bloodstream Increase heart rate, reddening of eyes, talkativeness and giddiness Some users may become quiet or reflective Marijuana and THC Medical uses of THC when made synthetically; Lessen nausea associated with Chemotherapy Help people with AIDS regain appetite Used to treat glaucoma Glaucoma is the build up of pressure on the eyeball. Marijuana and THC Effects on the Brain Increases level of dopamine Dopamine produces a pleasurable feeling. THC works by binding to specific receptors in the brain called "cannabinoid receptors," which are located throughout the following brain structures: Cerebellum Hippocampus Cerebral Cortex Limbic System Marijuana and THC Effects on the Brain Cerebellum By binding with the cannabinoid receptors THC interferes with the normal function of the cerebellum, which controls balance, posture, and coordination. Hippocampus THC activates cannibinoid receptors in the hippocampus. effects memory by decreasing nerve cell activity in this area. Short-term memory is the first to be affected. Marijuana and THC Effects on the Brain Cerebral Cortex THC affects areas in the cerebral cortex that are responsible for sensory perception. Sense of taste, sight, smell, hearing, and touch may be altered. Limbic System THC produces changes in the limbic system ( governs) our emotions. These changes, which are most evident during withdrawal from THC, are similar to those observed after long-term use of cocaine, heroin, and alcohol. Inhalants Are substances whose fumes are sniffed or inhaled to give effect. Types of inhalants Prescribed Inhalants Used to treat allergies, asthma, and other medical conditions. Solvents, Aerosols, Glues, Paints, Gasolines These if used can cause brain damage. Inhalants Effects on the body Depress the central nervous system Immediate effects Glassy stare, Slurred Speech, Impaired Judgment, Nausea, Coughing, nosebleeds, fatigue, and lack of coordination. Can lead to permanent loss of Brain Damage Long Term effects Liver and Kidney damage, Blindness, Brain damage, Paralysis, Cardiac Arrest and Death. Inhalants All inhalants are extremely dangerous Many labeled as poisons Can be harmful even if you are not trying to abuse them Can be accidentally inhaled when doing household chores. When using inhalants work in well-ventilated room and wear a mask when project requires long exposure to fumes. Steroids Can be prescribed for medical purposes Anabolic- androgenic steroids Synthetic substance similar to male sex hormones. Anabolic refers to muscle building Androgenic refers to increased male characteristics. Steroids Anabolic-Androgenic Steroids Synthetic derivatives of the naturally occurring male anabolic hormone (testosterone). Anabolic means “to build” Androgenic means “masculinizing” Steroids Testosterone is the primary male hormone responsible for the development of masculine traits Androgenic effect triggers the maturing of the male reproductive system. Anabolic effect helps body retain protein which aids in development of muscles ANABOLIC PROPERTY LURES ATHLETES! Steroids How it’s used Can be taken orally or injected. Injected steroids are broken down into additional categories Long-Lasting Short-Lasting Water-soluble injections Steroids Who takes steroids? Athletes, Men are stereotypically associated with steroids Anyone who uses desires to look, perform or feel better regardless of danger Steroids Health Hazards Transmitting or contracting HIV and Hepatitis B through needles. Side effects can occur long after you stop using Megadosing – using more than one type of steroid at a time Effects can be irreversible body damage. Steroids Physical Side effects Male Feminization effect Decrease in normal sexual function Reduced sperm count Impotence Development of Breasts Shrinking of Testicles Difficulty or pain while urinating Steroids Women Experience Masculinization effect Facial Hair Growth Deepened Voice Breast Reduction Menstrual Cycle Change Steroids Both Genders Acne Bloated Appearance Rapid Weight Gain Clotting Disorders Liver Damage Premature Heart Attacks and Strokes Elevated Cholesterol levels Weakened Tendons Steroids Special Dangers to adolescents Steroids close growth centers in a kid’s bones Once growth plates are closed they cannot reopen So adolescents may end up shorter than they should have been Steroids Addictive Long-time steroid users may experience addiction through: Cravings Difficulty in stopping Withdrawal Symptoms STEROIDS DO NOT HELP IMPROVE SKILL, AGILITY OR CARDIOVASCULAR CAPACITY! Psychoactive Drugs Chemicals that affect the function of the central nervous system and alter brain activity. Four main groups Hallucinogens Opiates Stimulants Depressants Psychoactive Drugs Some have medicinal value When misused and abused an individual’s health is seriously affected. Effects on TEEN’s developing brain and body especially damaging Psychoactive Drugs Consequences of psychoactive drugs Poor judgement and behaviors Unintentional injuries Violence STDs Unintended pregnancy Suicide Psychoactive Drugs Hallucinogens category of drugs that affect the brain in such a way that a person’s perceptions -- meaning their sights, sounds, feelings, and how they judge time -- become very different and unreal. Can cause changes with emotions, memory and judgement. Psychoactive Drugs LSD (Hallucinogen) Also known as acid, doses, trips, tabs, hits, sunshine, window pane, sugar cubes, microdot is a very powerful drug made with a chemical found in a fungus -- that grows on grains. Psychoactive Drugs LSD (Hallucinogen) It was originally developed as a treatment for mental patients, but doctors soon learned that it was too unpredictable to be useful. In the 1960’s, many people took LSD because they believed the drug “expanded the mind.” LSD is usually found as pieces of thin paper sprayed with the drug, which are eaten, or in liquid or gelatin form. Psychoactive Drugs - LSD Side Effects Changes in personality and mood Mood swings Hallucinations Delusions Intense fear Confused senses, like “seeing sounds” and “hearing colors” Dilated pupils Increased body temperature Sweating Loss of appetite Sleeplessness Dry mouth Tremors Psychoactive Drugs LSD (Hallucinogen) Health Risks Increased heart rate and blood pressure Long lasting mental problems, like schizophrenia or depression Psychoactive Drugs LSD (Hallucinogen) Problems with using Scary hallucinations can make people panic, which can lead them into dangerous situations. LSD “flashbacks” are very common, with the drug’s effects returning without warning from a few days to a year later. Users develop tolerance, meaning that they eventually need more and more of the drug to get the same effect. Psychoactive Drugs Opiates which means that it comes from a flower called the opium poppy. Opiates are used in hospitals as painkillers for patients in serious pain from injury, surgery, or illness; morphine is another opiate that you might see used for medical purposes. Psychoactive Drugs Heroin (Opiate) is a brown or white powder that is sometimes snorted or smoked. Most of the time, users turn it into a liquid and inject the drug into their veins with a needle. Psychoactive Drugs Heroin (Opiates) Side effects Euphoria, a “rush” of well-being Reduced pain Dry mouth Droopy eyelids and smaller pupils Flushed skin Heavy arms and legs Slow thinking and movement Slow and slurred speech Periods of sleepiness, sometimes called “the nod” Vomiting Constipation Considered to be the MOST ADDICTIVE DRUG Psychoactive Drugs Heroin (Opiates) Health Risks Collapsed veins Heart infections Pneumonia Death from overdose Psychoactive Drugs Heroin (opiate) Problems with Using Heroin is one of the most physically addictive drugs in the world, and breaking the addiction can be very difficult. Users develop tolerance, meaning that they eventually need more and more of the drug to get the same effect. Because heroin can be expensive, users often turn to crime to get drug money. Sharing needles can lead to infectious diseases, including hepatitis and AIDS. Psychoactive Drugs Heroin (Opiate) Problems with using Quitting the drug or “kicking the habit” can lead to bad withdrawal symptoms, including pain, nausea and vomiting, diarrhea, cold flashes, and an incredible craving to return to the drug. Quitting suddenly, called “going cold turkey,” can lead to death in long-term addicts in bad health. Psychoactive Drugs Stimulants are a class of drugs that elevate mood, increase feelings of well-being, and increase energy and alertness. often produce a feeling of euphoria in users. Examples are caffeine, amphetamines, methamphetamines and cocaine. Psychoactive Drugs Cocaine (Stimulants) is a powerfully addictive stimulant that directly affects the brain The pure chemical, cocaine hydrochloride, has been an abused substance for more than 100 years, and coca leaves, the source of cocaine, have been ingested for thousands of years Effects Dopamine in your brain! Psychoactive Drugs Cocaine (stimulant) Pure cocaine was first extracted from the leaf of the Erythroxylon coca bush, which grows primarily in Peru and Bolivia, in the mid-19th century. In the early 1900s, it became the main stimulant drug used in most of the tonics/elixirs that were developed to treat a wide variety of illnesses Psychoactive Drugs Cocaine (stimulants) How it’s used In powder form it can be snorted or dissolved into water and injected Crack is cocaine that has not been neutralized by an acid to make the hydrochloride salt. This form of cocaine comes in a rock crystal that can be heated and its vapors smoked. The term “crack” refers to the crackling sound heard when it is heated FASTER ABSORPTION MORE INTENSIFIED HIGH! Psychoactive Drugs Cocaine (Stimulants) Short Term Effects Euphoric Energetic Talkative Mentally alert Senses especially alert Decrease need for food or sleep Constricted blood vessels Dilated pupils Increased temperature Increased heart rate and blood pressure Psychoactive Drugs Cocaine (stimulants) Long Term effects Irritability Restlessness Paranoia Lead to paranoid psychosis the individual loses touch with reality and experiences auditory hallucinations Psychoactive Drugs Cocaine (Stimulants) Problems with using Dependence and addiction Cardiovascular problems, including irregular heartbeat, heart attack, and heart failure Neurological incidents, including strokes, seizures, fungal brain infections, and hemorrhaging in tissue surrounding the brain Pulmonary effects, such as fluid in the lungs, aggravation of asthma and other lung disorders, and respiratory failure Psychiatric complications, including psychosis, paranoia, depression, anxiety disorders, and delusions Psychoactive Drugs Cocaine (Stimulants) Problems with using Increased risk of traumatic injury from accidents and aggressive, violent, or criminal behavior Other effects include: sleeplessness, sexual dysfunction, diminished sense of smell, perforated nasal septum, nausea, and headaches. Crack users often singe eyebrows or eyelashes with the flame of matches or lighters. They also burn fingertips and other body parts from contact with superheated vessels (e.g., glass pipes). Psychoactive Drugs Cocaine (Stimulants) Problems with using Fetal cocaine effects include premature separation of the placenta, spontaneous abortion, premature labor, low birthweight and head circumference at birth, greater chance of visual impairment, mental retardation, genitourinary malformations, and greater chance of developmental problems. For intravenous (IV) cocaine users, there is increased risk of hepatitis, HIV infection, and endocarditis. For addicts, whether they smoke, inject, or snort, promiscuous sexual activity can increase the risk of HIV infection Psychoactive Drugs Depressants drugs that sedate by acting on the central nervous system. relieve anxiety and produce sleep. reduce mental or physical activity. Examples; barbiturates, benzodiazepines, and alcohol Psychoactive Drugs Depressants Medical Uses Help treat anxiety, insomnia, tension, muscle spasms, and irritability. Psychoactive Drugs Alcohol (depressants) Is a depressant that slows the central nervous system. Ethanol – is the type of alcohol in alcoholic beverages Can be produced synthetically or naturally by fermenting fruits, veggies, and grains. Fermentation is the chemical action of yeast on sugars. Water and minerals mixed to create beverages. Psychoactive Drugs Alcohol (Depressants) If a person consumes to much alcohol a person will become INTOXICATED! Intoxication – is a state in which the body is poisoned by alcohol or another substance, and a person’s physical and mental control is significantly reduced. ALCOHOL stays in a person’s system until body can metabolize or break it down! Psychoactive Drugs Alcohol (depressants) Factors that influence the effects of alcohol are: Body Size – smaller person faster that larger Gender – generally moves faster in blood in females. Food – food in the stomach slows down the passage of alcohol in bloodstream. Rate of intake – if a person drinks faster than the liver can break it down Amount – more intake more in bloodstream. Medicine – can heighten effect of alcohol Psychoactive Drugs Alcohol (Depressants) Short term effects of alcohol Memory is disorganized Judgement and control Movement, speech, and vision Risk of stroke Increase Heart rate and blood pressure Stomach acid production and can cause nausea and vomiting. Psychoactive Drugs Alcohol (Depressants) Long – Term effects Damage to brain cells and reduction in brain size. Stroke and Heart Attack Buildup of fat cells in liver that can lead to cell death. Damage to digestive lining of the stomach causing ulcers and cancer of the stomach Destruction of pancreas Psychoactive Drugs Alcohol (Depressants) Long Term effects Fetal Alcohol Syndrome Addiction