Cell Division - Meiosis Meiosis • Process of cell division that reduces the number of chromosomes in new cells to half the number in the original cell. • The haploid cells produced are called gametes. Meiosis • Cells preparing to divide by meiosis undergo the G1, S and G2 phases of interphase. Meiosis • Cells will then begin meiosis with a duplicate set of chromosomes. • Meiosis is divided into two stages called Meiosis I and Meiosis II. Meiosis I • Prophase I • DNA coils tightly into chromosomes, spindles appear, and the nuclear membrane disassembles. Prophase I • Each chromosome lines up next to its homologue. This is called synapsis. • Each pair of homologous chromosomes is called a tetrad. Prophase I • During this stage, crossing-over occurs. • This is when genetic material breaks off and attaches to the adjacent chromatids. • The result is genetic recombination. Metaphase I • Tetrads line up randomly along the midline of the dividing cell. • Spindles attach to the centromeres of the homologous chromosomes. Anaphase I • Each homologous chromosome moves to an opposite pole. • The chromosomes are separated randomly. This is called independent assortment. Telophase I • Chromosomes reach the opposite ends of the cell and cytokinesis begins Meiosis II • Meiosis II is not started by the copying of DNA. • There may be a short resting stage but usually there is no true interphase. Prophase II • Spindle fibers form and begin to move the chromosomes toward the midline of the cell Metaphase II • Chromosomes move to the midline of the cell. Anaphase II • The chromatids separate and move toward opposite poles of the cell. Telophase II • Cytokinesis occurs and produces 4 cells • A nuclear membrane forms around the chromosomes in each of the 4 new cells. Formation of Gametes • In males, meiosis occurs in the testes. This is called spermatogenesis. • Four sperm cells result from meiosis. Formation of Gametes • In females, meiosis occurs in the ovaries. This is called Oogenesis. Formation of Gametes • During cytokinesis for females, the cytoplasm is unequally divided. • This results in only 1 egg cell being formed and 3 polar bodies. Asexual Reproduction • Offspring from only one parent • Offspring are genetically identical • Occurs from binary fission or mitosis Sexual Reproduction • Offspring from two parents • Offspring are genetically different • Meiosis