Blood vessels Dejan Tkalec Mentor: A. Žmegač Horvat What are blood vessels? intricate networks of tubes that transport blood throughout the entire body Types of vessels: Arteries Veins Capillaries Sinusoids Arteries Veins Transport blood away from Transport blood towards the the heart Carry oxygenated blood Have relatively narrow lumens Have relatively more muscle/elastic tissue Transport blood under higher pressure Do not have valves (except for the semi-lunar valves of the pulmonary artery and the aorta) heart Carry de-oxygenated blood Have relatively wide lumens Have relatively less muscle/elastic tissue Transport blood under lower pressure Have valves throughout the main veins of the body (except venae cavae) Histology Arteries and veins have the same structure: 1. Tunica intima: single layer of simple squamous endothelial cells, surrounded by a thin layer of elastic bands – internal elastic lamina 2. Tunica media (thickest layer): circularly arranged elastic fibers, connective tissue, polysaccharide substances surrounded by external elastic lamina; rich in vascular smooth muscle (especially in arteries) 3. Tunica adventitia: entirely made of connective tissue; contains nerves that supply the vessel Functions Transporting blood away from the heart Transporting oxygenated blood across the body Transporting blood from arteries to capillaries Draining blood from capillaries into veins and exchanging oxygen, carbon dioxide, water and salt between the body and surrounding tissues Arterioles - main regulators of blood pressure and flow Capillaries - assist in supplying body tissues with necessary components of blood Common problems Aneurysm - weak spot in the wall of an artery Atherosclerosis - narrowing of the arteries caused by plaque deposits Heart disease - lack of blood supply to the heart because of narrowed arteries High blood pressure - can be caused by obesity, diabetes, rich salt diet, smoking, high cholesterol, kidney disease... Varicose veins - problems with valves that stop blood from running backwards Aorta Largest artery in the body, originating from the left ventricle of the heart and extending down to the abdomen, where it branches off into two common iliacs Usually divided into 5 segments: 1. Ascending aorta 2. Arch of aorta 3. Descending aorta 4. Thoracic aorta 5. Abdominal aorta Other major arteries References http://biology.about.com/library/organs/heart/blblood.htm http://en.wikipedia.org/wiki/Blood_vessel http://www.ivy- rose.co.uk/HumanBody/Blood/Blood_Vessels.php http://www.ehow.com/about_5110377_functions-bloodvessel.html http://video.about.com/heartdisease/How-the-HeartFunctions.htm