CELL: THE UNIT OF LIFE What is a cell? A cell is the smallest unit that is capable of performing life functions. All living organisms are composed of cells. Examples of cell: Amoeba Proteus Plant Stem Bacteria Red Blood Cell Nerve Cell Cell Theory All living things are made up of cells. Cells are the smallest working units of all living things. All cells come from preexisting cells through cell division. Discovery of cell: In 1665, Robert Hooke examined a thin slice of a cork under a microscope. He saw that it was made of thousands of tiny chambers. These chambers reminded him of the tiny rooms in a monastery, called cells. TYPES OF CELL: There are two types of cells: Prokaryotic cell Eukaryotic cell Characteristics of Prokaryotic cell: Cells that lack a membranebound nucleus are called prokaryotes (from the Greek meaning before nuclei). Cells in the monera kingdom such as bacteria and cyanobacteria (also known as blue-green algae) are prokaryotes. They don't have a membrane-bound nucleus and their genetic information is in a circular loop called a plasmid. Bacterial cells are very small, roughly the size of an animal mitochondrion (about 12µm in diameter and 10 µm long). Characteristics of Eukaryotic cell: Eukaryotic cells (from the Greek meaning truly nuclear) comprise all of the life kingdoms except monera. They can be easily distinguished through a membrane-bound nucleus. Eukaryotic cells also contain many internal membranebound structures called organelles. These organelles such as the mitochondrion or chloroplast Following are the Important Cellorganelles: Cell membrane Cell wall Endoplasmic reticulum Golgi apparatus Lysosome Vacuoles Mitochondria Plastids Ribosomes Cilia and Flagella Centrosome and centrioles Nucleus Microbodies Let us study about each of them individually……………………………… Cell membrane: Outer membrane of cell that controls movement in and out of the cell Double layer It is a multipurpose covering composed of phospholipids and proteins. Apart from the plasma membrane, an eukaryotic cell also shows intracellular and subcellular membranes around its organelles and vacuoles. A fluid mosaic model was given by singer and nicholson. Cell Wall: A cell wall is a characteristic feature of plant cells, bacteria and fungi. The composition however varies in different groups. cell wall is chiefly composed of insoluble polysaccharides, most common constituent is cellulose, pectin, hemicellulose, lignin and xylan may also be present. The cell wall is generally deposited in two layers a primary wall and a secondary wall. the cell wall is involved in some specific functions such as : Protection against the attack of pathogens Providing mechanical support Allowing movement of materials in and out of the cell Cytoplasm: The term cytoplasm can be used to describe the matrix of a cell found between its plasma membrane and the nucleus. It encloses various cell organelles and inclusions. The cytoplasm is a semi viscous jelly-like substance. It consists of an aqueous, almost transparent structureless ground substance called hyaloplasm or cytosol. Cytoplasm serves the following functions It is the seat of all metabolic and biochemical processes taking place in a cell. It is involved in the storage of raw materials or reserve food required by the cell. It brings about exchange of materials between the cell organelles. It exchanges materials with the surrounding environment such as extra cellular fluid. Endoplasmic Reticulum(ER): This is a complex network of tubes, the lumen of which is filled with fluid. Two types of endoplasmic reticula are seen. They are: Tubes with a smooth surface are called smooth endoplasmic reticula. They secrete lipids. Tubes with spherical bodies (ribosomes) attached are known as rough endoplasmic reticula. The functions of the endoplasmic reticulum are to form the skeletal framework of the cell, to provide a pathway for the distribution of nuclear material from one cell to the other and to synthesize fats, steroids and cholesterol with the help of enzymes secreted by the cell. Golgi apparatus Also known as Golgi Complex or Golgi Bodies, they consist of tiny, elongated, flattened sacs (cisternae), which are stacked parallel to one another along with some vacuoles and clusters of vesicles. The function of the golgi body is to secrete certain hormones and enzymes. It also forms lysosomes and peroxisomes. The golgi body is usually found close to the nucleus. Lysosomes: These are tiny, spherical, sac-like structures scattered all over the cytoplasm. Their main function is digestion. They contain powerful destructive enzymes capable of digesting all organic material, and hence called “digestive bags”. “suicide bag” is a sobriquet that is often used for Lysosomes. Vacuoles: Membrane-bound sacs for storage, digestion, and waste removal Contains water solution Help plants maintain shape Mitochondria: These may be cylindrical, rod-shaped or spherical and distributed in the cytoplasm. Each mitochondrion is bound by a double membrane. The inner membrane is folded into ridges called cristae, which increase the surface area of the membrane. It is in the mitochondria that the sugar is finally burnt during cellular respiration. The energy thus released is stored as high-energy chemicals called ATP (adenosine triphosphate). Hence, mitochondria are termed as the “power house” or the “power plant” of the cell. Plastids: These organelles are found only in plant cells. Plastids are of three types: Chloroplasts Chromoplasts Leucoplasts Chloroplasts They are green and found in leaves. The green colour is due to the presence of chlorophyll. Chromoplasts They are yellow, orange and red, and found in flowers and fruits. Leucoplasts They are colourless and found in roots, seeds and underground stems. The function of the chloroplast is to trap solar energy for photosynthesis. Chromoplasts impart colour to flowers to attract insects for pollination. Leucoplasts store food in the form of carbohydrates, fats and proteins. Ribosomes: These are spherical, granular particles which occur freely in the matrix or remain attached to the rough endoplasmic reticulum. Ribosomes contain RNA (ribonucleic acid) and proteins Their function is to provide the surface for protein synthesis. Cytoskeleton: An elaborate network of filamentous proteinaceous structures present in cytoplasm. They are involved in many functions as mechanical support, motility, maintenance of shape of cell etc. Cilia and Flagella: Hair-like outgrowths of the cell membrane Covered by plasma membrane Their core axoneme possesses a no. of microtubules parallel to long axis. Cilia are small hair-like structures which work like oars. Flagella are longer hair like structures which beat anteriorly or posteriorly. Flagella are of two types: 1.) Whiplash 2.)Tinsel Centrosome and Centrioles: Present only in animal cells Made up of two centrioles (cylindrical structures). The central part of proximal region of centriole is also proteinaceous and called hub. Function:formation of spindle fibres. Nucleus: This is a prominent, spherical or oval structure found at the centre of the cell. It is the controlling centre of all cell activities and has been described as the brain of the cell. It regulates all metabolic and hereditary activities of the cell. The nucleus is composed of the following structures: Nuclear Membrane Nucleoplasm Nucleolus Chromatin network Nuclear Membrane This is a double-layered membrane which separates the nucleoplasm from the cytoplasm. The nuclear membrane has minute pores which allow the selective transfer of material between the nucleoplasm and the cytoplasm. Nucleoplasm Within the nuclear membrane, completely filling up the space, is a clear, semisolid, granular substance or matrix called the nucleoplasm. The nucleolus and the chromatin network lie suspended in the nucleoplasm. Nucleolus This dense, spherical granule found in the nucleus contains RNA (ribonucleic acid) which is responsible for protein synthesis in the cytoplasm. Chromatin Network These are very fine thread-like, coiled filaments uniformly distributed in the nucleoplasm. At the time of cell division, the chromatin becomes thick and ribbon like and are known as chromosomes. The chromosomes contain genes, which are composed of DNA (deoxy-ribonucleic acid). Genes are responsible for storing and transmitting hereditary characteristics from one generation to another. A gene is the functional unit of a chromosome. Genes are arranged in single linear order along the chromosome. One gene may be responsible for a single characteristic, or a single characteristic may be transmitted by a set of genes. Types of chromosomes based on the position of centromere: Microbodies: Small sac like structures which contain various hydrolytic enzymes. 1- Nucleus 2- Chromosomes 3- Mitochondria 4- Ribosomes 5- Chloroplasts 6- Vacuoles 7- ER 8- Cell Membrane THANK YOU