Minerals and Antioxidants HOMEOSTATIC REGULATION OF MINERAL ELEMENTS Homeostasis is the term used to describe the ability of the body to maintain the content of a specific substance within a certain range despite varying intakes. Homeostasis involves the processes of absorption, storage, and excretion. The relative importance of these three processes varies among the trace elements. Excretion through the urine, bile, sweat, and breath is, therefore, the primary mechanism for controlling the amount of these trace elements in an organism. By being stored in inactive sites, some trace elements are prevented from causing adverse reactions when present in high quantities. An example of this homeostatic process is the storage of iron as ferritin. Release of a trace element from a storage site also can be important in preventing deficiency. What are minerals? Minerals are substances help the body to grow, develop, and stay healthy. The body uses minerals to perform many different functions — from building strong bones to transmitting nerve impulses. Some minerals are even used to make hormones or maintain a normal heartbeat General Characteristics of the Minerals: - Regulate body processes - Give structure to things in the body - No calories (energy) - Cannot be destroyed by heat Classification of Minerals: 1- Major minerals—macrominerals with special duties in the body; calcium, phosphorus, magnesium, sodium, chloride, and potassium 2- Trace minerals—minerals needed in only small amounts but serving vital body functions. Categories of minerals: 1- Major minerals: a. Calcium b. Phosphorus c. Magnesium 1 d. Electrolytes (sodium, chloride, potassium) b. Trace minerals 1. 2. 3. 4. 5. 6. 7. 8. Chromium Copper Fluoride Iodine Iron Manganese Selenium Zinc Essential Minerals and Their Functions Participates in the regulation of osmotic pressure and Fluid balance Participates in active transport mechanisms as part of the plasma membrane Na+K+ ATPase Muscles relax, transmit nerve impulses Regulates blood pressure - Ca is mainly extracellular mineral - Is an important cell signal with respect to metabolic regulation and the transport of metabolites (and some hormones) from one compartment to another or from one cell to the bloodstream - Is a key mineral in cell death, in muscle contraction, Heart rate and Nerve function - Play an important role in Teeth and Bone building - Helps in blood cloting - Participates in the regulation of osmotic pressure Participates in active transport mechanisms as part of the Na+K+ATPase Has a role in muscle contraction and Nerve impulses. Maintains blood pressure - Participates in the regulation of osmotic pressure and Fluid balance - Is a part of gastric acid (HCl) help in Digestion of food. - Transmits nerve impulses 2 - Is a good oxidizing agent - Participates in the exchange of oxygen for carbon dioxide - Important to vitamin B12 absorption - As a component of high-energy compounds (ATP, ADP, etc.) - Is a component of bones and teeth - Serves as a component of nucleic acids (RNA and DNA) - Part of 300 enzymes (regulates body functions) Maintains cells in nerves impulses, muscles relaxation. Component of bones and teeth Best sources are legumes, nuts, and whole grains - Part of hemoglobin, carries oxygen - Brain development - Healthy immune system Disorders: - Hypertension—high-blood pressure linked to high salt intake. - Osteomalacia—a disease caused by a lack of vitamin D in adults. - Osteoporosis—condition caused by calcium deficiency; bones become porous, weak, fragile. - Toxicity—An excessive amount of a substance that is poisonous in the body. Antioxidants - Antioxidants are molecules that prevent cell damage and serve as parts of enzymes. - There are many types of antioxidants found in nature. There are vitamin antioxidants that are known to be protective like vitamins A, C, and E. - There are mineral antioxidants like selenium and zinc and there are pigments (colors). Some pigments in plants and animals are potent antioxidants. - Antioxidants trap harmful forms of oxygen and prevent them from damaging cells. - Antioxidants in the diet enter the blood stream and act directly to protect cells of the body from damage. - In addition, some antioxidants stimulate the immune system, and/or increase the activity of detoxifying enzymes in the liver. 3 - Carotenoids – beta carotene (familiar) Vitamin C Vitamin E Found in colorful fruits/veggies and grains 4