Cardiovascular System: Blood Vessels Components of the Vascular System Tunics (Layers) Around Blood Vessels Blood Vessel Types Movement of Blood Through System Capillary Beds and Diffusion Major Arteries and Veins of the Body Hepatic Portal Circulation Fetal Circulation Blood Vessels: The Vascular System Taking blood to the tissues and back • Arteries o Arterioles Capillaries o Venules • Veins The Vascular System Three layers (tunics) • Tunic intima o Endothelium • Tunic media o Smooth muscle o Controlled by sympathetic nervous system • Tunic externa o Mostly fibrous connective tissue Figure 11.8b Differences Between Blood Vessel Types Walls of arteries are the thickest Lumens of veins are larger Walls of capillaries are only one cell layer thick to allow for exchanges between blood and tissue Movement of Blood Through Vessels Most arterial blood is pumped by the heart Veins use the milking action of muscles to help move blood Expansion of vein walls when lungs inflate pulls pulmonary artery blood in Figure 11.9 Capillary Beds Capillary beds consist of two types of vessels • Vascular shunt – directly connects an arteriole to a venule • Shunt operates during trauma, cold temps Figure 11.10 Capillary Beds True capillaries – exchange vessels o Oxygen and nutrients cross to cells o Carbon dioxide and metabolic waste products cross into blood Figure 11.10 Major Arteries of Systemic Circulation Internal carotid artery External carotid artery Common carotid arteries Vertebral artery Subclavian artery Brachiocephalic trunk Aortic arch Ascending aorta Coronary artery Thoracic aorta (above diaphragm) Celiac trunk Abdominal aorta Superior mesenteric artery Renal artery Gonadal artery Common iliac artery Inferior mesenteric artery Internal iliac artery (b) Illustration, anterior view Arteries that supply the upper limb Subclavian artery Axillary artery Brachial artery Radial artery Ulnar artery Deep palmar arch Superficial palmar arch Digital arteries Arteries that supply the lower limb External iliac artery Femoral artery Popliteal artery Anterior tibial artery Posterior tibial artery Arcuate artery The Arm and Thorax Vertebral artery Thyrocervical trunk Suprascapular artery Costocervical trunk Thoracoacromial artery Axillary artery Posterior circumflex humeral artery Anterior circumflex humeral artery Subscapular artery Brachial artery Deep artery of arm Common interosseous artery Common carotid arteries Left subclavian artery Right subclavian artery Brachiocephalic trunk Posterior intercostal arteries Anterior intercostal artery Internal thoracic artery Descending aorta Lateral thoracic artery Radial artery Ulnar artery Deep palmar arch Superficial palmar arch Digital arteries Arterial Supply of the Brain Anterior Frontal lobe Optic chiasma Cerebral arterial circle (circle of Willis) • Anterior communicating artery • Anterior cerebral artery • Posterior communicating artery • Posterior cerebral artery Basilar artery Middle cerebral artery Internal carotid artery Mammillary body Temporal lobe Pons Occipital lobe Vertebral artery Cerebellum Posterior (d) Major arteries serving the brain (inferior view, right side of cerebellum and part of right temporal lobe removed) Major Veins of Systemic Circulation Dural venous sinuses External jugular vein Vertebral vein Internal jugular vein Right and left brachiocephalic veins Superior vena cava Great cardiac vein Hepatic veins Splenic vein Hepatic portal vein Renal vein Veins that drain the upper limb Subclavian vein Axillary vein Cephalic vein Brachial vein Basilic vein Median cubital vein Ulnar vein Radial vein Digital veins Veins that drain the lower limb Superior mesenteric vein Inferior vena cava Inferior mesenteric vein External iliac vein Common iliac vein Popliteal vein Internal iliac vein Posterior tibial vein Femoral vein Great saphenous vein Anterior tibial vein (b) Illustration, anterior view. The vessels of the pulmonary circulation are not shown. Small saphenous vein Dorsal venous arch Dorsal metatarsal veins Hepatic Portal Circulation Figure 11.14 Pressure/Pulse Points Superficial temporal artery Facial artery Common carotid artery Brachial artery Radial artery Femoral artery Popliteal artery Posterior tibial artery Dorsalis pedis artery Figure 19.12 Circulation to the Fetus Modif 1 Modif 2 Handling of collapsed lungs Measuring Arterial Blood Pressure Measurements by health professionals are made on the pressure in large arteries • Systolic – pressure at the peak of ventricular contraction • Diastolic – pressure when ventricles relax Pressure in blood vessels decreases as the distance away from the heart increases Listen for the sounds of Kortokoff Normal BP is 120/75-80 Blood pressure animation online Using a cuff online Comparison of Blood Pressures Disease causing blood pressure change Arteriosclerosis: Hardening of the artery walls and decrease of elasticity, restricting flow and increasing blood pressure. Atherosclerosis: A specific type of arterosclerosis where arteries are clogged by an accumulation of plaques: cholesterol particles (lipoproteins), fat, calcium, cellular waste and other substances. One-way valves in veins prevent backflow where positive pressure is at a mininum Blood Pressure: Effects of Factors Blood Pressure = Cardiac Output x Total Peripheral Resistance BP = CO x TPR Neural factors • Renal factors • Regulation by altering blood volume: salt and water retention • Renin – hormonal control Temperature • Heat has a vasodilating effect • Cold has a vasoconstricting effect Chemicals • Autonomic nervous system adjustments (sympathetic division): vasoconstriction Various substances can cause increases or decreases Diet • High salt causes elevated BP Variations in Blood Pressure Human normal range is variable • Normal o 140–110 mm Hg systolic o 80–75 mm Hg diastolic • Hypotension o Low systolic (below 110 mm HG) o Often associated with illness or physical conditioning • Hypertension o High systolic (above 140 mm HG) o Can be dangerous if it is chronic Developmental Aspects of the Cardiovascular System A simple “tube heart” develops in the embryo and pumps by the fourth week The heart becomes a four-chambered organ by the end of seven weeks Few structural changes occur after the seventh week Congential heart defects sometimes arise Hypertrophy of the heart occurs through regular aerobic exercise Varicose veins develop as we age, along with atherosclerosis, & hypertension Congenital Heart Defects Varicose Veins