URINARY SYSTEM 1 URINARY SYSTEM • AKA Excretory system • Removes certain wastes and excess water • Maintains the acidbase balance 2 URINARY STRUCTURES • 2 KIDNEYS • 2 URETERS • BLADDER • URETHRA 3 KIDNEYS • 2 BEAN-SHAPED ORGANS 4 KIDNEYS LOCATION: -BESIDE VERTEBRAL COLUMN -BEHIND ABDOMINAL CAVITY (Retroperitoneal space) 5 KIDNEYS • Protected by a cushion of fat and the ribs • Held in place by connective tissue • Enclosed in a mass of fatty tissue called the adipose capsule • Covered by tough fibrous tissue called the renal fascia 6 KIDNEYS DIVIDED INTO 2 MAIN SECTIONS: Renal cortex and renal medulla 7 CORTEX • Outer section of the kidney • Contains most of the filtering units called nephrons (which aid in the production of urine) 8 MEDULLA • INNER SECTION OF KIDNEY • CONTAINS MOST OF THE COLLECTING TUBULES (WHICH CARRY THE URINE FROM THE NEPHRONS THROUGH THE KIDNEYS) 9 NEPHRONS • Microscopic filtering units • Over a million in each kidney 10 NEPHRONS • CONSISTS OF: -Glomerulus -Bowman’s capsule -Proximal convolutes tubule - Loop of Henle -Distal convoluted tubule -Collecting duct 11 RENAL ARTERIES Carry blood to the kidneys Branches pass through the medulla to the cortex where blood enters the glomerulus 12 GLOMERULUS • A cluster of capillaries • Filtered from the blood: water, salt, sugar, metabolic products and other substances • Does not filter red blood cells and protein out of the blood • Substances that were filtered out enter the Bowman’s capsule 13 BOWMAN’S CAPSULE • C-Shaped structure • Surrounds the glomerulus • Is the beginning of the proximal convoluted tubule • Passes the filtered substances into the convoluted tubules 14 TUBULES • Filtered substances that are needed by the body are reabsorbed in the convoluted tubules • Most of the sugar, water and salts are reabosorbed • Urea, uric acid and creatinine remain in the tubules 15 URINE • Made up of concentrated liquid called urea, uric acid, creatinine, mineral salts, pigments and 95% water, • Liquid waste product of the urinary system • The presence of sugar or protein may indicate disease 16 URINE • The kidneys produce about 1500 to 2000 ml (cc) of urine per day (1 ½ to 2 quarts) • The kidneys filter about 150 quarts of blood per day • From the Bowman’s capsule, the urine enters the convoluted tubules and goes to the collecting ducts in the renal medulla 17 COLLECTING DUCTS • Located in the renal medulla • AKA tubules • Empty into the renal pelvis (renal basin)(which forms the first part of the ureter) 18 URETERS • Two muscular tubules • 10 - 12 inches long • Extends from the renal pelvis to the bladder • Peristalsis moves urine down the tubules 19 BLADDER • A hollow muscular sac located in the pelvis • Located behind the symphysis pubis • Midline in the pelvic cavity • Lined with a mucous membrane 20 BLADDER • Mucous membrane is arranged in folds called rugae • The rugae disappear as the bladder fills and expands 21 BLADDER FUNCTIONS • Receives urine form the kidneys • Stores the urine until it is expelled from the body 22 BLADDER MUSCLES • A circular sphincter muscle controls the opening leading from the bladder • As the bladder fills receptors in the wall sends a message to the brain • The brain sends the sphincter muscle a message to relax and release the urine 23 URETHRA • Tube that carries urine from the bladder to the outside of the body • The external opening is called the urinary meatus • The urethra is different in males and females 24 FEMALE URETHRA -FEMALES: urethra is about 1 ½ inches long -opens in front of the vagina -carries urine ONLY 25 MALE URETHRA -MALES: about 8 inches long and s-shaped -passes through the prostate gland -carries BOTH urine and semen 26 POLYURIA EXCESS URINATION 27 OLIGURIA BELOW NORMAL AMOUNT OF URINE 28 ANURIA ABSENCE OF URINE 29 HEMATURIA BLOOD IN URINE 30 NOCTURIA URINATION AT NIGHT 31 DYSURIA PAINFUL URINATION 32 RETENTION INABILITY TO EMPTY BLADDER 33 INCONTINENCE INVOLUNTARY URINATION 34 DISEASES OF THE URINARY SYSTEM 35 CYSTITIS • Inflammation of the urinary bladder usually due to an ascending urinary tract infection. • Symptoms: decreased bladder capacity, an urgent need to urinate frequently day and night, feelings of pressure, pain, and tenderness around the bladder and pelvis. • Treatment: antibiotics 36 NEPHRITIS • Nephritis is a term used to clinically denote a group of renal disorders associated with hypertension, decreased renal function, hematuria, and edema. • Nephritis is a noninfectious inflammatory process involving the nephron; glomerulonephritis (GN) generally is a more precise term. 37 PYELONEPHRITIS • Pyelonephritis is a kidney infection, usually from bacteria that have spread from the bladder. • Possible causes of kidney infection include the following: -infections in the bladder -use of a catheter to drain urine from the bladder -use of a cystoscope to examine the bladder -surgery on the urinary tract -conditions such as prostate enlargement and kidney stones that prevent the efficient flow of urine from the bladder -efects or abnormalities in the urinary tract that block the flow of urine 38 Symptoms of Pyelonephritis -back, side, and groin pain -urgent, frequent urination -pain or burning during urination -fever -nausea and vomiting -pus and blood in the urine 39 RENAL CALCULUS • Kidney stones, also called renal calculi, are solid concretions (crystal aggregations) of dissolved minerals in urine; calculi typically form inside the kidneys or bladder. The terms nephrolithiasis and urolithiasis refer to the presence of calculi in the kidneys and urinary tract, respectively. • Symptoms of kidney stones include: -Colicky pain: "loin to groin". Often described as the "the worst pain I've ever experienced" -Hematuria: blood in the urine, due to minor damage to inside wall of kidney, ureter and/or urethra -Dysuria: burning on urination when passing stones (rare). More typical of infection. -Oliguria: reduced urinary volume caused by obstruction of the bladder or urethra by stone, or extremely rarely, simultaneous obstruction of both ureters by a stone. -Nausea/vomiting 40 Renal Calculus (stones) 41 RENAL FAILURE • • • Renal failure or kidney failure is a situation in which the kidneys fail to function adequately. It is divided in acute and chronic forms; either form may be due to a large number of other medical problems. Acute renal failure (ARF) is a rapidly progressive loss of renal function, generally characterized by oliguria (decreased urine production, quantified as less than 400 mL per day in adults; body water and body fluids disturbances; and electrolyte derangement. An underlying cause must be identified to arrest the progress, and dialysis may be necessary to bridge the time gap required for treating these fundamental causes. ARF can result from a large number of causes. Chronic renal failure can either develop slowly and show few initial symptoms, be the long term result of irreversible acute disease or be part of a disease progression. There are many causes of CKD. The most common cause is diabetes mellitus. 42 Dialysis – treatment of Renal Failure 43 The END of the Urinary System 44