Unit 1: Intro to Biology & Biochemistry Learning Targets: 1. I can apply criteria that scientists use to evaluate the validity of scientific claims and theories. (SC-H-I-S-6) Reliability and Validity The principles of validity and reliability are fundamental cornerstones of the scientific method. The idea behind reliability is that any significant results must be more than a one-time finding and be repeatable. Other researchers must be able to perform exactly the same experiment, under the same conditions and generate the same results. This will reinforce the findings and ensure that the wider scientific community will accept the hypothesis. Validity encompasses the entire experimental concept and establishes whether the results obtained meet all of the requirements of the scientific research method. For example, there must have been randomization of the sample groups and appropriate care and diligence shown in the allocation of constants. 2. I can safely use laboratory equipment and techniques when conducting scientific investigations. (AE 2.1) List 2 situations in which goggles must be worn: a. Using chemicals b. Open flame and/or heating liquids 3. I can describe the biological criteria that need to be met in order for an organism to be considered alive. (prior knowledge-SC-4-UDU-1) Describe 4 characteristics that are essential to living organisms: a. Cells All organisms are made of one or more cells. Cell is the basic unit of life. b. Use Energy Organisms need a source of energy. Some make their own food with sunlight through photosynthesis. Animals get energy eating other organisms. c. Respond to Environment Organisms react to light, temperature, touch, sound, and other parts of their environment. Ex. Plants grow toward light. d. Reproduction and Development Members of a species must be able to reproduce, or make new organisms. The offspring grow and develop, through a life cycle, and pass on genetic info (DNA). 4. I can compare the types of bonding between atoms to form molecules. (SC-HS-1.1.7) List and describe 3 types of bonding: a. Ionic Bond: forms between oppositely charged ions that have lost or gained electrons. Ex. NaCl- table salt b. Covalent Bond: forms when atoms share a pair of electrons— forming molecules Ex. H and O in water molecule are held together by covalent bond. c. Hydrogen bond: Attraction between slightly positive and negative polar ends of molecules like water. Causes cohesion in water. 5. I can define and explain the unique properties of water that are essential to living organisms. (SC-HS-1.1.5) Cohesion- The attraction among molecules of the same substance. Cohesion from hydrogen bonds between water molecules cause water to stick to other water molecules. Adhesion- The attraction among molecules of different substances. Water molecules stick to other things—Capillarity in plants helps move water from roots to leaves. High Specific Heat- Hydrogen bonds give water this property. Water resists changes in temperature, helping cells to maintain homeostasis ( a stable balance). 6. I can describe the general structure and function(s) of the carbon compounds. (SC-HS-4.6.5) Organic Compound Carbohydrate Monomer (building blocks) Function *Main source of energy Monosaccharide *Structure in cell wall of plants Examples Mono- glucose, Lactose-milk sugar Sucrose-table sugar Cellulose- dietary fiber Amino acids Protein Lipid Nucleic Acid *Structural framework; *ENYZMES -Control metabolism Lactase- digests lactose Bromelain- protease in pineapples Fatty acid *Long-term energy storage; *insulation; *protective coverings, *component in cell membrane Fats, oils, waxes, steroids Nucleotide *Stores genetic code *Protein synthesis DNA, RNA 7. I can describe the function of enzymes, including how enzymesubstrate specificity works, in biochemical reactions. (SC-HS-3.4.2) How do enzymes affect biological reactions? They decrease the __activation_________________________energy necessary to initiate the chemical change causing the reaction to speed up. Describe each step: 1. The substrates are beginning to bind to the enzyme. 2. The enzyme is causing new bonds to form between the substrates. 3. The catalyzed reaction is releasing a product. 8. I can design and conduct an experiment. (AE 2.1) Methods of Scientists I. The Nature of Scientific Investigation A. Question 1. Identify a problem. 2. What is it you want to know? 3. Research the problem. 4. Design a test and define the variables 5. State a ___hypothesis________________________a suggested explanation for an observation. If…then… statement. 6. Make a prediction. B. Test/Experimentation: an organized procedure that involves making measurements and observations. 1. Select a sample. 2. Determine how the variables will be controlled and measured. Test only C. one______variable______________________________: changeable factor a.___Independent_________________________________ ___ variable: the factor that is manipulated by the experimenter. b. ___Dependent________________________________ variable: a factor that is affected by the experiment and observed/measured. c. __Constants_____________________________________ _: factors that do not change in an experiment d. ______Control________________________________ ___: Used in an experiment as comparision to show that the results are due to the condition being tested. 3. Conduct the experiment. (Remember Lab Safety!) 4. Make accurate observations and measurements. 5. Record the results—Data Table Analyze 1. Organize the data using graphs, tables, and charts. D. 2. Look for trends in the data. 3. Compare the data with the hypothesis and the prediction. Conclude 1. Look at the data, make inferences and form conclusions. 2. If data does not support the original hypothesis, reevaluate the hypothesis. 3. Formulate new questions. 9. I can communicate experimental findings/evidence in an authentic form by writing a formal lab report. (AE 2.2; Literacy/Writing in Science)