Module Specification An online version of this specification is available to prospective students at http://www.lshtm.ac.uk/study/currentstudents/studentinformation/msc_module_handbook/section3_moduledescript/in dex.html GENERAL INFORMATION Module name Modelling & the Dynamics of Infectious Diseases Module code 2464 Module Organisers Dr Richard White, Dr Emilia Vynnycky and Dr Adam Kucharski Contact email Richard.White@lshtm.ac.uk Emilia.Vynnycky@lshtm.ac.uk Adam.Kucharski@lshtm.ac.uk Home Faculty Faculty of Epidemiology & Population Health Level This module is at Level 7 (postgraduate Masters ‘M’ level) of the QAA Framework for Higher Education Qualifications in England, Wales & Northern Ireland (FHEQ). Credit LSHTM award 15 credits on successful completion of this module. Accreditation Not currently accredited by any other body. Keywords Infectious Disease Modelling, [HIV/AIDS, Bacterial, TB, Malaria, Viral Disease prevention & control, Research (in general), Epidemiology (incl. surveillance), Quantitative methods. AIMS, OBJECTIVES AND AUDIENCE Overall aim To introduce students to key methods for setting up models of the transmission dynamics of infectious diseases and their application. Intended learning outcomes By the end of this module, students should be able to: Understand the basic methods for setting up deterministic and stochastic infectious disease models; Understand some of the host and pathogen factors determining variation in infectious diseases over time and how to incorporate these into models; Analyse seroprevalence data using models to estimate age and timedependent transmission rates and their application for understanding control of childhood infections; Understand the applications of modelling in infectious disease epidemiology and of some of the insights that models have provided, including describing the time-course of outbreaks and predicting the impact of control strategies; Understand the application of modelling to measles, mumps, rubella and influenza, STI/HIV, tuberculosis, vector-borne diseases and applications in veterinary epidemiology; 1 Target audience Critically read and interpret modelling papers. The course aims to bring a conceptual understanding of mathematical models and their applications in infectious disease research to individuals who have not had any advanced training in mathematics. It is also suitable for individuals with a background in mathematical disciplines who wish to obtain an understanding of the broad range of applications of mathematical models in infectious disease epidemiology and who may wish to specialize in this area in the future. CONTENT Session content The module is expected to include sessions addressing the following topics (though please note that these may be subject to change): Basic methods and motives for developing infectious disease models; Analysis and applications of seroprevalence data: methods for elucidating age (and time-) dependent transmission; application for designing models for predicting the impact of control strategies; Additional methods and dynamics - stochastic and network modelling, model-fitting and sensitivity analyses; Applications of modelling. TEACHING, LEARNING AND ASSESSMENT Study resources provided or required Course folder provided Teaching and learning methods A variety of teaching methods are employed including lectures, computer practicals, small group work and paper discussions. The course will introduce participants to the use of mathematical models for analysing a wide range of problems involving many different pathogens, and will equip participants with the skills to build and analyse simple models for their own area of interest. We use periodic review sessions to consolidate and expand on concepts covered during the course. Paper discussion sessions are included to enhance understanding of modelling papers and to encourage critical thinking of model structures and the underlying assumptions. Assessment details The assessment consists of two components: a data analysis/modelling exercise that students carry out in small groups (20%) and an MCQ exam taken individually (80%) of 1.5 hours. For students who are required to re-sit, or granted a deferral or new attempt, the task will be an individual MCQ exam of 1.5 hours. Assessment dates The groupwork assessment is carried out during the 3rd or 4th week of the module. The MCQ occurs in the final week of the module For students who are required to re-sit, or who are granted a deferral or new attempt, the next assessment date will be the standard School-recommended date in mid/late September 2016. Language of study and assessment English (please see ‘English language requirements’ below regarding the standard required for entry). 2 TIMING AND MODE OF STUDY Duration The module runs for 5 weeks at 2.5 days per week; this module runs between Monday morning and Wednesday lunchtime. Dates For 2015-16, the module will start on Monday 24 February 2016 and finish on Wednesday 23 March 2016. Timetable slot The module runs in LSHTM timetable slot D1. Mode of Study The module is taught face-to-face in London. Both full-time and part-time students follow the same schedule. For full-time students, other LSHTM modules are available in the other half of the week for the C and D slots. Learning time The notional learning time for the module totals 150 hours, consisting of: Contact time ≈ 50 hours Directed self-study ≈ 35 hours Self-directed learning ≈ 20 hours Assessment, review and revision ≈ 25 hours APPLICATION, ADMISSION AND FEES Pre-requisites This module builds on and consolidates many of the themes covered in the module on the Epidemiology & Control of Communicable Diseases (2437), and attendance at that module (or equivalent knowledge) is beneficial, but not required. Students will need to have an understanding of basic epidemiology. Students will benefit from reading the first chapter of the book “An Introduction to Infectious Disease Modelling” by E Vynnycky and RG White before the start of the course. They may also find it helpful to work through the exercises in the basic maths chapter of this book or through the maths refresher which will be posted on Moodle before the course. Familiarity with the spreadsheet package Excel is important (those with no experience should attend introductory courses). Training in the modelling package Berkeley Madonna is provided. Specialist mathematical training is not required as the emphasis is on developing a conceptual understanding of the basic methods and their practical application. Students who have attained the equivalent of a good high school mathematics training have generally been able to benefit from the course. English language requirements A strong command of the English language is necessary to benefit from studying the module. Applicants whose first language is not English or whose prior university studies have not been conducted wholly in English must fulfil LSHTM’s English language requirements, with an acceptable score in an approved test taken in the two years prior to entry. Applicants may be asked to take a test even if the standard conditions have been met. Student numbers Student numbers are typically 40-70 per year; numbers may be capped due to limitations in facilities or staffing. 3 Student selection Preference will be given to LSHTM MSc students and LSHTM research degree students. Other applicants meeting the entry criteria will usually be offered a place in the order applications are received, until any cap on numbers is reached. Applicants may be placed on a waiting list and given priority the next time the module is run. Full Registration (full participation) by LSHTM research degree students is required for this module. Fees For registered LSHTM MSc students, fees for the module are included within MSc fees (given on individual course prospectus pages). If registering specifically for this module, as a stand-alone short course, individual module fees will apply. Tuition fees must be paid in full before commencing the module, or by any fee deadline set by the Registry. Scholarships Scholarships are not available for individual modules. Some potential sources of funding are detailed on the LSHTM website. Admission deadlines For 2015-16: For registered LSHTM MSc students, the module choice deadline (for Term 2 and 3 modules) is Friday 20 November 2015 . If registering specifically for this module, applications may be made at any time but, as places are limited, applications ahead of the MSc deadline are strongly advised. All applications should be submitted at the latest 8 weeks prior to the start of the module. Formal registration will take place on the morning of the first day of the module. ABOUT THIS DOCUMENT This module specification applies for the academic year 2015-16 Last revised 23 June 2014 by Richard White Minor amendments SDB 20th July 15 London School of Hygiene & Tropical Medicine, Keppel St., London WC1E 7HT. www.lshtm.ac.uk 4