Case Study Paper: Bleeding During Pregnancy Ashley Deal University of Central Florida Case Presentation S.W. is a 28 year old female patient G1P0 who came into the office complaining of frequent vaginal bleeding without cramping. She is 26 weeks and 2 days pregnant based on last menstrual period consistent with eight week sonogram with an estimated due date of January 22, 2014. She is not currently bleeding. She states that she has had bleeding throughout her pregnancy. S.W. has gone to the emergency department twice during her pregnancy for episodes of excessive vaginal bleeding. She received a comprehensive work up including a transvaginal ultrasound and blood work. The patient states she would saturate a menses pad with frank red blood in about an hour lasting between three and four hours at a time. She has noted a small amount of blood daily throughout her pregnancy since about 12 weeks. She denies any pain and cramping associated with bleeding episodes. S.W. denies any past medical or surgical history. She started her menses at the age of 14 and she reports normal monthly periods. Her last menstrual period was April 17, 2013. The patient denies any surgical history. The patient has no known allergies. The patient is currently taking a daily prenatal vitamin with iron supplement by mouth and Tums as needed for heartburn typically one to two times per week. The patient denies any family medical history. She currently lives in a single family home with her husband. Both the patient and her husband are nonsmokers and the patient denies alcohol or illicit drug use. She is in a monogamous relationship with her husband and has not been sexually active since the confirmation of pregnancy. She denies any previous sexually transmitted infections. The patient works as a paralegal in a small law firm. She sits at a desk for the majority of the day. She is not currently exercising or engaging in any strenuous physical activity. The patients’ last Pap smear was in May 2013 and was within normal limits. The patient denies any previous abnormal pap smears. The prenatal lab work was all within normal limits. The patients’ blood type is A+, rubella: immune, HIV: negative, STI’s: negative, HSV: negative, RPR: negative, CMV: positive. The patient had a normal one hour glucose tolerance test done at 24 weeks and 4 days of 93. Her hemoglobin in the office today is 13.1. Her urine dipstick in the office today is within normal limits. The patient denies any headaches, head trauma, lesions or masses. The patient denies cough, sputum production, wheezing, or hemoptysis. The patient denies any chest pain, dizziness, palpitations, or edema. The patient denies any skin lesions, rashes, or breakdowns. The patient denies nausea, vomiting, or cramping. The patient denies any difficult urinating, pain, frequency, or hesitation. No foul smelling urine or vaginal discharge. The patient notes frequent vaginal bleeding during pregnancy, but denies bleeding at this time. The patient denies any syncope or weakness. The patient denies any history of anemia or blood disorder and denies any bruising. The patient denies muscle aches, swelling, or joint pain. The patient denies any depression, anxiety, or suicidal thoughts or ideation. The patient denies any intolerance to heat or cold, any changes in weight, hair or hat, shoe size. The patient states positive fetal movement on a daily basis. The patient denies any preterm labor. S.W. is a 29 year old well- nourished Caucasian female in no apparent distress. She is 26 weeks pregnant today. The patient is 5’3” and weighs 143 pounds with a 12 pound weight gain during her pregnancy thus far. Her vitals are all within normal limits with a temperature of 98.2, respirations of 16, heart rate of 82, and blood pressure of 112/64. The fetal heart rate is in the 140’s. Her physical exam is unremarkable. She is alert and oriented to person, place, time, and situation. The patient has normal skin turgor, no edema, no rashes, erythema, or lesions noted. Her skin is warm, dry, and intact. Her heart rate and rhythm are normal, no murmur auscultated, no palpable thrills or heaves. Her lungs are clear bilaterally to auscultation, her breathing is nonlabored with no use of accessory muscles, no clubbing noted. The abdomen is soft, non-tender with no palpable masses and no guarding present, positive bowel sounds in all four quadrants. The fundal height is 24.5 cm. The patient is able to move all extremities without pain or tenderness. Full ROM in all extremities, no crepitus or limitation noted. Muscle strength is +5, equal bilaterally. Deep tendon reflexes are symmetrical bilaterally in the upper and lower extremities, measuring 2 +. Gait is even and coordinated. The external genitalia are normal with no masses or lesions noted. The cervix is tight and closed today. Scant amount of dark brown discharge noted in the vaginal canal, no other discharged noted. The patient appears healthy today. Differential Diagnosis Based upon the patients’ presentation, assessment, and diagnostic testing the most likely differential diagnosis for this patient are placenta praevia, placental accrete, and ectopic pregnancy. The patient is having abnormal vaginal bleeding during pregnancy without cramping, nausea, or vomiting. About half of patients who have bleeding during pregnancy have no known cause (Yang et al, 2004). Placenta praevia is a condition in which the placenta covers all or part of the cervix, which can lead to antepartum bleeding (Rao et al, 2012). Placenta praevia typically presents with third trimester painless bleeding (Rao et al, 2012). The third trimester begins at 28 weeks. S.W. is still in her second trimester, but she is reporting painless bleeding. Guidelines from the Society of Obstetricians and Gynecologists of Canada recommend the use of transvaginal ultrasound to diagnosis and evaluate placenta praevia (Oppenheimer, 2007). Placenta accrete refers to when the placenta is implanted into the uterus with varying degrees and can lead to bleeding during the pregnancy (Wortman & Alexander, 2013). Patients at greatest risk for developing placenta accreta are those who have a history of myometrial damage secondary to previous cesarean delivery (ACOG, 2012). S.W. has not had a previous cesarean delivery and has no myomentrial damage at this time. Placenta accreta is diagnosed with the use of grayscale ultrasonography and MRI can be performed in ambiguous cases (ACOG, 2012). Ectopic pregnancy is a condition in which the fetus develops outside of the uterus and presents with vaginal bleeding, pelvic pain, and palpable adrenal mass (Lozeau & Potter, 2005). S.W. reports vaginal bleeding, but does not report pelvic pain and no mass was palpated on exam. Diagnostics A transvaginal or pelvic ultrasound is performed to diagnosis placenta previa and placental accraeta (ACOG, 2012. Fetal heart rate should be monitored to assess for abnormalities (RCOG, 2011). Laboratory results that are important to evaluate bleeding in patients include a complete blood count, PT, aPTT, and fibrogen level to evaluate blood count for anemia and coaguability (Buttaro, 2013). The patient had a non-stress test done today. The fetus had a reactive non-stress test with an average heart rate in the 140’s. While hospitalized the patient had a transvaginal ultrasound performed which showed a partial placenta previa with minimal pooling. The patient also had a fetal ultrasound while hospitalized which was within normal limits for gestational age. A hemoglobin result was obtained in the office which showed a hemoglobin level of 13.1. Treatment Plan Follow up transvaginal ultrasound should be performed at 32 weeks for patients with placenta previa to assess the position of the placenta and a final ultrasound should be performed at 36 weeks (Rao et al, 2012). The American Congress of Obstetricians and Gynecologists recommends late preterm or early term delivery for patients with placenta previa (ACOG, 2013). The patient should be educated on the likelihood of an early delivery. Proper education is vital to ensure the patient is compliant with her prenatal care to decrease the likelihood of further complications during her pregnancy. In order to reduce the risk of antepartum hemorrhage there is no evidence to support bed rest, reduced activity, or avoidance of sexual intercourse (Rao et al, 2012). Aerobic exercise is contraindicated in patients with placenta previa and persistent bleeding during the second and third trimester (ACOG, 2002). Discussion The patient was placed on bed rest with minimal activity as well as no sexual intercourse although there is no clear evidence to support that those interventions will decrease the risk of antepartum bleeding. The patient was informed to continue taking a prenatal vitamin with folic acid daily. The patient was ordered to have non-stress tests twice a week as well as serial ultrasounds for fetal growth and development per the maternal fetal specialist in the office. The patient was advised to monitor for fetal movement daily. Education in regards to early preterm labor was provided to the patient consistent with the recommends from The American College of Obstetricians and Gynecologists. S.W. was informed that if she has another episode of excessive bleeding, saturating a menses pad within an hour, then to immediately go to the hospital for evaluation. She was advised to return to the office in two weeks and as needed. This patient was pregnant for the first time and is experiencing a pregnancy complicated by frequent vaginal bleeding. Due to the complications during her pregnancy so far this patient was suffering from anxiety as well. Maternal anxiety can lead to neurobiobehavioral dysregularities in infants (Parcells, 2010). It is important to monitor this patient for her anxiety and to prevent further pregnancy complications as well as impacting the infant. Vaginal bleeding during pregnancy is common and often undiagnosed, but it is important to provide patients with a full work up to rule out any severe complications. The treatment plan in place for the patient followed conservative management and were primarily based upon guidelines, but also components of the plan were based on the provider’s personal preference. I felt as though the treatment plan for the patient was appropriate and agree with the conservative management to ensure the best possible outcome for the patient and baby. References Buttaro, T. M., Trybulski, J., Bailey, P. P., & Sandberg-Cook, J. (2013). Primary Care A Collaborative Practice (4th ed.). St. Louis: Elsevier. Lozeau, A.-M., & Potter, B. (2005). Diagnosis and Management of Ectopic Pregnancy. American Family Physician, 1707-1714. Oppenheimer, L. (2007, March). Diagnosis and Management of Placenta Previa. Retrieved December 5, 2013, from SOGC Clinical Practice Guideline: http://sogc.org/wpcontent/uploads/2013/01/189E-CPG-March2007.pdf Parcells, D. (2010). Women's mental health nursing: depression, anxiety and stress during pregnancy. Journal Of Psychiatric & Mental Health Nursing, 17(9), 813-820. doi:10.1111/j.1365-2850.2010.01588.x Rao, K., Belogolovkin, V., Yankowitz, J., & A. (2012). Abnormal placentation: evidence-based diagnosis and management of placenta previa, placenta accreta, and vasa previa. Obstetrical & Gynecological Survey, 67(8), 503-519. doi:10.1097/OGX.0b013e3182685870 Royal College of Obstrectrians and Gynecaolgists. (2011, January). Placenta Praevia, Placenta Praevia Accreta and Vasa Praevia: Diagnosis and Management. Retrieved December 5, 2013, from http://www.rcog.org.uk/files/rcogcorp/GTG27PlacentaPraeviaJanuary2011.pdf The American College of Obstetricians and Gynecologists. (2002, January). Exercise During Pregnancy and the Postpartum Period. Retrieved December 6, 2013, from http://www.acog.org/Resources_And_Publications/Committee_Opinions/Committee_on_ Obstetric_Practice/Exercise_During_Pregnancy_and_the_Postpartum_Period The American Congress of Obstetricans and Gynecologists. (2013, April). Medically Indicated Late-Preterm and Early-Term Deliveries. Retrieved December 5, 2013, from http://www.acog.org/Resources_And_Publications/Committee_Opinions/Committee_on_ Obstetric_Practice/Medically_Indicated_Late-Preterm_and_Early-Term_Deliveries The American Congress of Obstetricians and Gynocologists. (2012, July). Placenta Accreta. Retrieved December 5, 2013, from http://www.acog.org/~/media/Committee%20Opinions/Committee%20on%20Obstetric% 20Practice/co529.pdf?dmc=1&ts=20131206T1313193031 Wortman, A., & Alexander, J. (2013). Placenta accreta, increta, and percreta. Obstetrics & Gynecology Clinics Of North America, 40(1), 137-154. doi:10.1016/j.ogc.2012.12.002 Yang, J., Hartmann, K., Savitz, D., Herring, A., Dole, N., Olshan, A., et al. (2004). Vaginal Bleeding during Pregnancy and Preterm Birth. American Journal of Epidemiology, 118125.