NATIONAL INSTITUTE OF TECHNOLOGY, ARUNACHAL PRADESH, YUPIA, Pin-791112 (Established by MHRD, Govt. of India) Website : www.nitap.in, Fax No: (0360) 2284972 E-Mail: nitarunachal@gmail.com / admin@nitap.in DEPARTMENT OF BIOTECHNOLOGY & CHEMICAL ENGINEERING Exercises Proposed for teaching in (January –May, 2016 Semester) 1. 2. 3. 4. Name of the Teacher Department Course Title Course code Dr. Kimjolly Lhouvum Biotechnology & Chemical Engineering Cell Biology BT-404 5. Course Hands out (in reference to framed & approved syllabus) (maximum 500 words) Contents Class estimate Unit I: An overview of cells and cell research Origin and evolution of cells, cells as experimental models, tools of 12 classes cell biology – chemistry of cells – molecular composition of cells, central role of enzymes, metabolic energy, biosynthesis of cell constituents, cell membrane. Nucleus, Endoplasmic reticulum, Golgi apparatus and Lysosomes, Bioenergetics and Metabolism – Mitochondria, chloroplasts, Peroxisomes. Unit II: Cell structure and function Cell cycle, the cytoskeleton and cell movement, cell surface – transport of small molecules, Endocytosis, cell –cell interactionsAdhesion junctions-Tight junctions-Gap junctions- Plasmodesmata 8 classes Unit III: Cell signaling – cell regulation Signaling molecules and their receptors, functions, pathways of intracellular signal transduction–the Cell Cycle – Mitosis and Meiosis –Cell death and cell renewal-Programmed cell death-Stem cellsEmbryonic stem cells and therapeutic cloning. 10 classes Unit IV: Cancer The Development and causes of cancer, tumour viruses, oncogenes, prevention and treatment. 8 classes 6. Books/Literature to be followed: (a) Books (Min. 2 texts + 3 references) NATIONAL INSTITUTE OF TECHNOLOGY, ARUNACHAL PRADESH, YUPIA, Pin-791112 (Established by MHRD, Govt. of India) Website : www.nitap.in, Fax No: (0360) 2284972 E-Mail: nitarunachal@gmail.com / admin@nitap.in DEPARTMENT OF BIOTECHNOLOGY & CHEMICAL ENGINEERING (i) (ii) (iii) (iv) Title Author Publisher Edition Title Author Publisher Edition Title Author Publisher Edition Title Author Publisher Edition The Cell: A molecular approach Geoffrey M.Cooper, Robert E. Hausmann ASM Press 6th edition Essential cell biology Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson Garland Science Sixth Cell Biology Gerard Karp Wiley 6th Molecular Cell Biology Lodish, Harvey Krieger, Monty Kaiser, Chris A. Berk, Arnold, W H Freeman 6th (b) Magazines/Journals (Minimum 5) 1. Cell - ScienceDirect and Cell Press 2. PNAS - USNAS 3. Bioorganic & Medicinal Chemistry - ScienceDirect 4. Nature – Nature Publishing Group 5. Journal of Genetics and Genomics- Elsevier 6. FEBS Letters- Elsevier 7. Mode of Teaching: J.C Bose √ /S. N. Bose (please tick). 8. If the course is of practices, list the experiments to be offered. (i) Microscopic study of cell and cell organelles (ii) Cell fractionation (iii) Fixation, Dehydration, embedding and sectioning of tissues (iv) Histology of extracellular matrix (v) Isolation of Cytoskeleton (microtubules, actin and Myosin filaments) (vi) Isolation of Mitochondria (vii) Nuclear staining (viii) Stages of cell cycle NATIONAL INSTITUTE OF TECHNOLOGY, ARUNACHAL PRADESH, YUPIA, Pin-791112 (Established by MHRD, Govt. of India) Website : www.nitap.in, Fax No: (0360) 2284972 E-Mail: nitarunachal@gmail.com / admin@nitap.in DEPARTMENT OF BIOTECHNOLOGY & CHEMICAL ENGINEERING Are the manuals ready for the experiments to be conducted? Yes √ /No (please tick) If “No”, the reasons there of and fixing responsibility __________________________________________ __________________________________________ __________________________________________ __________________________________________ Remarks/ Endorsement by the HoD With his /her signature with date Name of the Teacher: Dr. Kimjolly Lhouvum Designation: Assistant Professor & Head Signature with Date: