Meiosis is the type of nuclear division that reduces the chromosome number from the diploid (2n) number to the haploid (n) number. In humans, the diploid number of 46 is reduced to the haploid number of 23. 2 Gametes (reproductive cells, often the sperm and egg) have the haploid number of chromosomes (1n). Fusion of gametes form a cell called a zygote. A zygote always has the full or diploid (2n) number of chromosomes. In plants and animals, the zygote undergoes development to become an adult organism. 3 In diploid body cells, the chromosomes occur in pairs which are called Homologous chromosomes or homologues. 4 Exchange of genetic material between non-sister chromatids of a bivalent during meiosis. (This occurs during Meiosis 1 / Prophase 1). 5 Meiosis requires two nuclear divisions and produces four haploid daughter cells, each having half the total number of chromosome. • Production of haploid gametes to maintain the diploid number of species, generation after generation. • Crossing-over, which brings together new gene combination of chromosomes and that lead to genetic variations. 7 MEIOSIS CONSISTS OF TWO UNIQUE CELL DIVISIONS Meiosis I Prophase I Metaphase I Anaphase I Telophase I Meiosis II Prophase II Metaphase II Anaphase II Telophase II 8 9 10 11 12 In human males, spermatogenesis occurs within the testes, and in females, oogenesis occurs within the ovaries. Secondary The testes of Primary spermatocytes human male undergo spermatocytes with 46 chromosomes contain stem cells meiosis II to produce called undergo meiosis I to spermatogonia, and four spermatids with 23 form two secondary these cells keep the daughter chromosomes. testes suppliedeach spermatocytes, Spermatids with primary then with 23 duplicated spermatocytes that differentiate into viable undergo chromosomes. sperm (spermatozoa). spermatogenesis. 14 Theother ovaries contain The is a polar body The result of meiosis I They even begin stem cells called that may either is two haploid cells oogenesis, but only a oogonia thator produce disintegrate divide with 23 chromosomes, few continue when a many primary again. The secondary One of these cells, female is sexually oocytes with 46 oocyte begins meiosis II termed the secondary mature. chromosomes during but stops at metaphase oocyte receives fetal development. II. Then the secondary almostleaves all thethe ovary oocyte and enters an oviduct. cytoplasm. 15 Video link for mitosis on http://www.youtube.com/watch?v=65SODTL_QsA (Right Click then choose open Hyperlink) Download the video (student must watch most of it) 16 17 البالغ (يقصد بها النضوج الجنسي) adult تبادل Exchange عملية انتاج الحيوانات المنوية Spermatogenesis عملية انتاج البويضات Oogenesis الخصيتان testes المبيض ovaries Test Your Self إختبر نفسك 18 1- Sexual reproduction _____. A) requires haploid gametes B) results in a diploid zygote C) creates offspring that are genetically different from the parents D) All of these 2- Once duplicated, a chromosome is composed of two identical parts called _____. A) sister chromatids B) centromeres C) homologous chromosomes D) chiasmata 3- Sexual reproduction contributes greatly to the process of _____. A) evolution B) metabolism C) organization D) growth and repair 19 4- The combining of chromosomes from genetically different gametes occurs during _____. A) crossing over B) synapsis C) meiosis II D) fertilization 5- In animals the haploid cells produced by meiosis mature and become _____. A) spores B) zygotes C) gametes D) diploid 6- A primary spermatocyte with 46 chromosomes will undergo meiosis and yield _____. A) four spermatids with 46 chromosomes B) four spermatids with 23 chromosomes C) two spermatids with 46 chromosomes D) two spermatids with 23 chromosomes 20 7- In females, meiosis is a part of _____, which occurs in the ovaries and produces eggs. A) fertilization B) oogenesis C) the alternation of generations D) spermatogenesis 8- When a primary spermatocyte undergoes meiosis I, two _____ secondary spermatocytes are produced. A) diploid B) haploid C) triploidy 9- Mitosis occurs in humans during _____. A) development of the zygote B) growth of a child C) repair of tissue at any time D) All of these 21 10 - Which phase is characterized by the haploid number of duplicated chromosomes at the metaphase plate? A) meiosis II metaphase II B) mitosis prophase C) meiosis II telophase II D) meiosis I metaphase I 11- Which of the following results in diploid daughter cells? A) meiosis I B) meiosis II C) mitosis 12- Which is true of both meiosis II and mitosis? A) Pairing of chromosomes B) Diploid number of chromosomes at the metaphase plate C) Separation of sister chromatids D) Four daughter cells 22 13- Which is characteristic of meiosis I? A) Pairing of chromosomes B) Separation of sister chromatids C) Diploid daughter cells D) All of these 14- At the end of telophase II and cytokinesis there are __________ haploid cells. A) two B) four C) six 15- The homologues of each bivalent separate and move to opposite poles during _____. A) prophase I B) metaphase II C) anaphase I D) anaphase II 23 16- Crossing over between nonsister chromatids occurs during _____. A) interkinesis B) prophase I C) telophase I D) anaphase II 17- Turner's syndrome is _______. A) produced by mutation B) produced by nondisjunction of an autosome C) produced by nondisjunction of an X chromosome D) trisomy X 18- Down Syndrome is an example of _______. A) polyploidism B) trisomy C) monosomy D) abnormality in embryonic development 24 19- At the completion of meiosis II, there are _____ daughter cells. A) two haploid B) two diploid C) four haploid D) four diploid 20- The diploid number of chromosomes is restored after _____ so that an animal's body cells contain the diploid number of chromosomes. A) meiosis I B) meiosis II C) fertilization 25 Thank You 26