Digestion Vocabulary: Malnourished: to be missing one or more essential nutrients Undernourishment: caloric deficiency Vitamins: organic molecules required in the diet Minerals: simple inorganic molecules Substrate-feeders: live on or in their food source, eating their way through the food Deposit-feeder: eat their way through dirt or partially decayed organic material Fluid-feeders: suck nutrient-rich fluids from a living host Bulk-feeders: eat relatively large pieces of food Ingestion: the act of eating, first stage of food processing Digestion: the process of breaking food down into molecules small enough for the body to absorb, second stage of food processing Enzymatic hydrolysis: the splitting process by adding a molecule of water and breaking covalent bonds Absorption: the animal’s cells take up (absorb) small molecules such as amino acids and simple sugars from the digestive compartment, third stage Elimination: the passing of undigested material out of the digestive compartment Intracellular digestion: the joining of food vacuoles and lysosomes to allow chemical digestion to occur within the cytoplasm of a cell Extracellular digestion: the breakdown of food outside cells Gastrovascular cavities: digestive sacs with single openings that function in both digestion and distribution of nutrients throughout the body (simple body) Complete digestive tracts/Alimentary canals: digestive tube extending between two openings, a mouth and an anus (most body types) Gastric juice: digestive fluid Pepsin: an enzyme in gastric juice the begins hydrolysis of proteins Acid chyme: nutrient-rich broth in the stomach Pyloric sphincter: helps regulate the passage of chyme into the intestine Bile: produced by the liver, stored in the gallbladder, contain bile salts that act as Detergents that aid in digestion/absorption of fats Emulsification: a process that keeps tiny fat droplets from coalescing Peristalsis: rhythmic waves of contraction by smooth muscles in the wall of the canals, pushes food along the tract Sphincters: ring like valves that close off the tube like draw strings, regulating the passage of material between chambers of the canal Salivary glands: exocrine glands that lubricate food, adhere together chewed Pieces, and begin process of chemical digestion Salivary amylase: an enzyme in saliva that hydrolyzes starch and glycogen Pharynx: a junction that opens to both the esophagus and the wind pipe (trachea) Epiglottis: a cartilage flap at the top of the trachea blocking the glottis Esophagus: conducts food from the pharynx to the stomach Stomach: secretes gastric juice and mixes this secretion with the food by the churning action of smooth muscles Small intestine: enzymatic hydrolysis and nutrient absorption Large intestine/colon: between the small intestine and the anus, water absorption and formation of poop Cecum: a blind outpocket of a hollow organ such as an intestine Appendix: small, finger-like extension of the cecum, contains a mass of white blood cells that contribute to immunity Rectum: where poop is stored until it can be eliminated Nutritional Requirements: Satisfy 3 needs: Fuel(Chemical energy) Organic raw materials used in biosynthesis(carbon skeletons make many of their own molecules) Nutrients that the animal cannot make for itself Glucose Regulation/ Example of Homeostasis: 1. The level of glucose rises above a set point 2. The pancreas secretes insulin 3. Insulin enhances the transport of glucose into body cells and stimulates the liver and muscle cells to store glycogen. Blood glucose levels drop 4. Sometimes it falls below the set point 5. In this situation the pancreas secretes the hormone glucagon(opposes the effect of insulin) 6. Glucagon promotes the breakdown of glycogen and the release of glucose into the blood, increasing blood glucose level Excess calories used for biosynthesis Liver and muscle cells store energy in the form of glycogen If caloric intake exceeds caloric expenditure, excess is stored as fat Essential Amino Acids Animals require 20 amino acids to make proteins 8 amino acids are not produced by oneself Overview of Food Processing: Chewing breaks apart the food while the enzyme amylase, in saliva, breaks it apart further In the throat/pharynx, the swallowed food goes through the esophagus because the epiglottis is blocking off the trachea The esophagus sends the food to the stomach Stomach the stomach makes gastric juice secreted by the epithelium lining, and makes pepsin the enzyme that begins the hydrolysis of proteins pepsin is first secreted in its inactive form pepsinogen and parietal cells secrete hydrochloric acid that converts it into its active from pepsin epithelial cells secrete mucus to prevent the stomach from digesting itself acid chyme is slowly released from the stomach, through the pyloric sphincter to the small intestine Small Intestine: Where most of the absorption of nutrients into the blood and enymatic hydrolysis occurs In the first 25cm of the small intestine, the duodenum, the chyme from the stomach mixes with digestive juices from the pancreas, liver, gallbladder, and gland cells The jejunum and ileum function mainly in the absorption of nutrients and water Pancreas: Produces several hydrolytic enzymes and an alkaline solution rich in bicarbonate The bicarbonate acts as an buffer that offsets the acidity of the chyme Liver: Produces bile that contains no digestive enzymes, but contains bile salts, that aid in the digestion and absorption of fats Gallbladder: stores bile until needed Absorption of Nutrients Large circular folds in the lining of the small intestine have finger like projections called villi, and each epithelial cell of a villus as microvilli that are exposed to the intestinal lumen Nutrients are pumped against the concentration gradient by epithelial membranes. This active transport allows the intestine to absorb a lot of nutrients Large Intestine/Colon: Connected to the small intestine at a T shape junction with the cecum Recovers water that has entered the alimentary canal Helps in vitamin synthesis Wastes of the digestive tract (feces) becomes more solid as it passes through the colon by peristalsis Living in the colon is a rich flora of mostly harmless bacteria (E. Coli) At the end of the colon is the rectum where poop is stored until it can be eliminated Hormones Help Regulate Digestion: When we see, smell, or taste food, impulses from the brain to the stomach initiates the secretion of gastric juice Certain substances in the food stimulate the stomach wall to release the hormone gastrin into the circulatory system Other hormones, collectively called enterogastrones, are secreted by the wall of the duodenum The acidic pH of the chyme that eneters the duodenum stimulates the cells in the wall to release the hormone secretin Cholecystokinin is secreted in response to the presence of amino or fatty acids