Digestive and Respiratory Supplemental Instruction Iowa State University Leader: Course: Instructor: Date: Kristina AnS 214 Keating 12/9/2013 Digestive System 1. The digestive system is made up of two groups of organs the ______________________ which includes the esophagus and stomach and the _________________ digestive organs which includes the teeth and tongue. The six processes involved in digestion are ______________, _______________, __________________, _____________________, ______________, and __________________. Saliva contains ___________________ for starch digestion and ______________________ which is activated by stomach acid. Salivation can be triggered by _____________, _____________, and _____________ of food during the ________________ phase. This stage also includes ___________ secretions and _____________. After food has been broken down and moistened in the mouth it moves into the ________________ in the form of a bolus. The bolus is then pushed along by contractions called ________________. It then reaches the stomach where chemical digestion of ___________ and ______________ begins. When food enters the stomach a _______________________ response occurs where the stomach resists stretch, but then relaxes to allow space for the food. In the gastric pits are _____________ cells that produce HCl and intrinsic factor and ______________ cells that secrete inactive pepsinogen. HCl activates _____________________ and ________________ which begin digestion of proteins and fats. __________________ cells control the mixing of food and chemicals by regulating the frequency of peristaltic waves. This makes up the _______________ phase of digestion. The final intestinal phase begins when food moves into the _____________________ which is made up of three parts the duodenum, _______________, and ________________. The __________ secretes bile which is then stored in the ________________. Bile is then injected into the small intestine where ________________ function to emulsify and absorb fats. The pancreas functions in protein digestions by secreting _______________, _____________, and ____________________ into the small intestine. The small intestine has structural modifications such as ______________, ______________, and _______________ that increase its ability to absorb nutrients. Food is moved along through the process of intestinal _______________. This process includes ____________________ and peristaltic ____________. Contents of the small intestine are moved along towards the ____________________. The presence of food in the ________________ causes the large intestine to undergo mass movements in the __________________________. This forces feces into the ______________. ________________ control allows the external anal sphincter to relax, while a _________________________ is responsible for the relaxation of the internal anal sphincter. This process is called _________________. Nutrient Digestion 2. Carbohydrate digestion begins in the _________________. However, it is halted in the stomach due to the inactivation of ______________________ by acid. ______________ amylase resumes carbohydrate digestion in the small intestine. Other ________________ enzymes act on other sugars such as fructose. Protein digestion begins in the _____________ due to the action of ___________________ (inactive). This inactive form is activated by __________. In the small intestine the enzymes _______________, Supplemental Instruction 1060 Hixson-Lied Student Success Center 294-6624 www.si.iastate.edu _____________________, and ______________________ continue protein digestion. Fat digestion takes place in the _______________________. Bile salts ______________ fat globules. Pancreatic _______________ then breaks down the fat into free _______________________ and monoglycerides. They combine with bile salts to form _______________ which ferry the components to the intestinal mucosa. The fatty acids and monoglycerides leave the ______________ and enter epithelial cells. They then form __________________. These are extruded by ___________________ and enter ______________. Finally they are carried away by _____________. Respiratory System 3. The upper respiratory system which is also the ___________________ zone has three functions: ___________, ______________, and ______________ inhaled air. Cells in this zone secrete _______________ to trap any foreign particles. If a particle makes it past this area it will come into contact with the _______________ which will result in a coughing reflex to expel it. The final part of the respiratory system, which resides in the respiratory zone, is the ________________. This is where ______________________ occurs. __________________ is the amount of air moving in and out during normal respiration. ____________________ is the maximum amount of air inspired after maximal expiration. Dead space is the space in the ___________________ where air remains and cannot undergo gas exchange. _____________ dead space also includes ______________ dead space. Alveolar ventilation rate is _______________ X ___________________________. The respiratory system has three characteristics: ________________ which is the ability to stretch, ________________ which is the tendency to return to original size and shape, and ______________________ which is the attraction between like molecules. Due to Boyle’s Law (___________________) air can enter the lungs. Inspiration is an ________________ process, but expiration is a _______________ process. The pressure of each gas on the lungs is dependent upon is proportion in the total mixture. This is _______________ Law. ________________ Law says that the amount of gas dissolved in a liquid depends on the solubility, _______________, and ____________________ of the gas. Oxygen is transported in the blood by ______________________ which can load ____ oxygen molecules at a time. Carbon dioxide is primarily transported as _________________. 4. Diagram the production of HCl. 5. Diagram an alveolus. 6. Describe what is happening in the diagram below. 7. Review the table of digestive substances. Inactive Hormone (if applicable) Trypsinogen Activating Factor Enterokinas e, trypsin Active Substance Function Location Trypsin Brush border Chymotrypsinogen Trypsin Chymotrypsin Procarboxypeptidase Trypsin Carboxypeptidase None Acid and fat in small intestine CCK None Acid and fat in small intestine Secretin None Increase in stomach pH Gastrin None Food Salivary Amylase None Carbohydrat es Pancreatic Amylase Protein digestion, activation of other hormones Protein digestion Protein digestion at carboxyl end Inhibit gastric secretion and motility Inhibit gastric secretion and motility Increase stomach secretions Starch digestion Starch digestion Pepsinogen HCl Pepsin None Proteins Aminopeptidase Chief cells/ stomach Brush border None Proteins Dipeptidase None RNA RNase None DNA DNase None Fat in duodenum High blood sugar Pancreatic Lipase Protein digestion Protein digestion at amine end Break up dipeptides Degrade RNA Degrade DNA Fat digestion Lower blood sugar Low blood sugar Glucagon None None Insulin Brush border Brush border Duodenum Duodenum G cells Mouth Pancreas Brush border Pancreas Pancreas Pancreas Pancreas Raise Pancreas blood sugar None Alcohol None Fat in duodenum None Food ACh None Food Histamine None Food HCl None HCl Lingual Lipase None Serotonin None Acid and fat in duodenum Acid and fat in duodenum Bacteria None Bacteria Lysozyme None Food Mucus None Acid and fat in small intestine Gastric Inhibitory Peptide None Alcohol Dehydrogenase Bile Somatostatin Ig A Alcohol digestion Fat emulsificati on Increase stomach secretions Increase stomach secretions Activate pepsin, break up cells walls, kill bacteria Digest fats Inhibit gastric secretion Inhibit gastric secretion Inhibit bacterial growth Kill bacteria Lubrication for swallowing Suppress gastric secretion and motility Stomach Liver/ gallbladder Stomach Enteroendocrine cells Parietal cells/ stomach Mouth, active in stomach Stomach Stomach Mouth Mouth Mouth Duodenum