Snapshot of IMS LifeLink Claims Database 10% Random Sample Prepared by: Gary W. Moore and Bradley C. Martin Health Data Unit of the UAMS Translational Research Institute What is LifeLink? • LifeLink is an administrative claims database – Captures bills paid to health providers by over 80 insurance and managed care plans. • Demographic and enrollment information – Geographic (state and zip3) of member residence • Diagnostic information (ICD-9-CM) • Procedures (HCPCs CPT-4) and Lab tests • Prescriptions Dispensed – Adjudicated claims for more than 40 million unique enrollees per year • 2006-2013 – 10% ember random sample obtained by UAMS TRI Outline of LifeLink Statistics • Demographic Characteristics • Plan Characteristics – HMO, PPO, Commercial, Medicare • Geographic Representation • Utilization – Inpatient, Office, Hospital outpatient – Most frequent diagnostic categories treated IMS LifeLink PharMetrics Plus™ – U.S. Age and Gender Distribution of Plan Members Distribution (N, %) of Enrollees by Gender Distribution (N, %) of Enrollees by Age Groups Missing 8,419 0.094% 65+: Elderly 838,040 9.345% Unknown 6,054 0.068% Male 4,413,685 49.216% 13-18: Teen 723,269 8.065% 0-12: Child Female Male Female 4,548,327 50.717% 0-12: Child 1,108,367 12.359% Unknown 51-64: Adult III 1,825,661 20.357% 31-50: Adult II 2,734,952 30.497% 13-18: Teen 19-30: Adult I 31-50: Adult II 19-30: Adult I 51-64: Adult III 1,729,358 65+: Elderly 19.284% Missing IMS LifeLink PharMetrics Plus™ – U.S. Gender and Age Distribution of Plan Members Gender by Age Group 3,000,000 538 2,500,000 1,400,229 2,000,000 529 958 Unknown 1,500,000 Female 944,449 867,126 Male 290 1,000,000 539,946 483 226 500,000 861,274 568,131 369,311 0 1,334,185 439,346 353,732 880,683 398,211 IMS LifeLink PharMetrics Plus™ – U.S. LifeLink Members Covered by State IMS LifeLink PharMetrics Plus™ – U.S. Proportion of Population Enrolled in LifeLink by State IMS LifeLink PharMetrics Plus™ – U.S. Length of Enrollment of Plan Members Percent of Total Enrollees (8,968,066) by Total Months Enrolled (Jan 2006 - Jul 2013) 16 14.13 14 12 10 8 13.94 Average patient enrollment = 33.31 months N (%) patients w/ enrollment > 2 years = 4.7 million (52.37%) 10.91 8.65 7.87 6.38 6 4 6.44 6.28 6.28 5.27 3.81 3.95 2.1 2 0 2.3 1.69 IMS LifeLink PharMetrics Plus™ – U.S. Pharmacy Benefits Enrollment of Plan Members Percent of Total Enrollees (8,968,066) by Total Months Enrolled (Rx Benefit) (Jan 2006 - Jul 2013) 18 Proportion of subjects without pharmacy benefits 15.51 16 13.9 14 12 10.57 10 8.65 7.53 8 6 4 2 0 Average patient enrollment = 28.99 months N (%) patients w/ enrollment > 2 years = 4.09 million (45.59%) 5.78 6.12 4.92 5.06 4.54 3.65 4.65 3.62 1.75 2.01 1.73 IMS LifeLink PharMetrics Plus™ – Arkansas LifeLink Members by 3 Digit Zip Code Area in Arkansas IMS LifeLink PharMetrics Plus™ – Texas LifeLink Members by 3 Digit Zip Code Area in Texas IMS LifeLink PharMetrics Plus™ – U.S. Distribution of Payer Type of Plan Members Number of Enrollees (N, %) by Pay Type Group Medicare Risk only; 55,477; Rx 0.62% Only ; 0; 0.00 Medicare Risk and Any % Other; 21,645; 0.24% Self-Insured only; 2,442,836; 27.24% Medicare Cost only; 28,258; 0.32% All other Pay Type combinations; 71,772; 0.80% Commercial and Self-Insured; 252,039; 2.81% All other Pay Type combinations Commercial and Self-Insured Commercial only Medicaid and/or SCHIP Medicare Cost only Medicare Risk and Any Other Medicare Risk only Rx Only Self-Insured only Medicaid and/or SCHIP; 142,129; 1.58% Commercial only; 5,953,910; 66.39% IMS LifeLink PharMetrics Plus™ – U.S. Distribution of Payer Type by Children, Adults, and Elderly Number of Enrollees by Pay Type Group by Age Group 7,000,000 184,563 6,000,000 5,000,000 Commercial and Self-Insured Commercial only 4,000,000 Medicaid and/or SCHIP 4,284,460 Medicare Cost only Medicare Risk and Any Other Medicare Risk only 3,000,000 Self-Insured only All other Pay Type combinations 2,000,000 43,940 1,163,353 1,000,000 1,694,763 23,534 500,317 537,138 210,186 0 0-18: Child 19-64: Adult 65+: Elderly IMS LifeLink PharMetrics Plus™ – U.S. Distribution of Payer Type by Year Number of Enrollees by Pay Type Group by Year 5,000,000 16,868 15,556 4,500,000 19,633 4,000,000 14,695 20,331 14,653 3,500,000 Commercial and Self-Insured Commercial only 12,715 3,218,790 3,000,000 4,875 3,050,029 2,642,195 2,547,502 Medicare Cost only 2,420,528 Medicare Risk and Any Other 2,776,241 2,500,000 Medicaid and/or SCHIP Medicare Risk only 2,000,000 2,019,236 2,371,805 Rx Only Self-Insured only All other Pay Type combinations 1,500,000 67,571 73,527 85,139 88,866 86,941 39,827 60,709 1,000,000 37,171 1,324,241 1,333,725 1,358,286 1,397,108 1,327,074 1,089,295 500,000 968,462 683,182 0 2006 2007 2008 2009 2010 2011 2012 2013 IMS LifeLink PharMetrics Plus™ – U.S. Distribution of Insurance Product Type of Plan Members Number of Enrollees (N, %) by Product Type Group All other Product Type combinations Preferred Provider Organization (PPO) only; 6,352,896; 70.84% Consumer Directed Health Care only Health Maintenance Organization (HMO) only Preferred Provider Organization (PPO) and Any Other; 556,027; 6.20% Indemnity/Traditional only Point of Service (POS) only Preferred Provider Organization (PPO) and Any Other Preferred Provider Organization (PPO) only Point of Service (POS) only; 545,027; 6.08% Indemnity/Traditional only; 267,692; 2.98% Health Maintenance Organization (HMO) only; 979,005; 10.92% Consumer Directed Health Care only; 36,417; 0.41% All other Product Type combinations; 231,002; 2.58% IMS LifeLink PharMetrics Plus™ – U.S. Distribution of Insurance Product Type of Children, Adults, and Elderly Number of Enrollees by Product Type by Age Group 7,000,000 6,000,000 665,580 388,376 5,000,000 400,175 Consumer Directed Health Care only Health Maintenance Organization (HMO) only 4,000,000 Indemnity/Traditional only Point of Service (POS) only Preferred Provider Organization (PPO) and Any Other 3,000,000 Preferred Provider Organization (PPO) only All other Product Type combinations 4,502,659 2,000,000 211,897 109,790 94,700 1,000,000 100,950 46,514 61,001 1,335,843 509,219 0 0-18: Child 19-64: Adult 65+: Elderly IMS LifeLink PharMetrics Plus™ – U.S. Distribution of Insurance Product Type by Year Number of Enrollees by Product Type Group by Year 5,000,000 14,711 18,906 4,500,000 642,732 580,564 4,000,000 10,138 601,864 3,500,000 227,270 254,661 21,444 208,239 514,575 421,386 386,376 49,171 50,885 112,833 213,911 54,363 34,013 480,602 91,971 207,048 29,608 7,995 3,000,000 518,224 40,519 408,640 82,991 201,374 28,782 357,640 320,667 41,390 2,500,000 Consumer Directed Health Care only 39,530 78,998 172,404 8,698 219,491 336,429 2,000,000 3,265,982 3,231,584 3,242,747 3,117,958 2,692,332 2,454,069 1,970,450 500,000 0 2006 Point of Service (POS) only Preferred Provider Organization (PPO) and Any Other All other Product Type combinations 3,263,166 1,000,000 Indemnity/Traditional only Preferred Provider Organization (PPO) only 52,997 1,500,000 Health Maintenance Organization (HMO) only 2007 2008 2009 2010 2011 2012 2013 IMS LifeLink PharMetrics Plus™ – U.S. Descriptive Statistics for Enrollees with at least one Retail Pharmacy Rx Fill in Year Millions Number of Retail Pharmcy Rx Fills by Year 40 35 30 25 20 15 10 5 0 Retail Pharmcy Rx Fills 2006 2007 2008 2009 2010 2011 2012 2013 17,577,180 30,444,424 36,120,978 36,028,158 33,040,719 31,387,382 29,475,951 12,253,831 NOTE: Year 2013 is limited to the months from January to July. IMS LifeLink PharMetrics Plus™ – U.S. Descriptive Statistics for Enrollees with at least one Retail Pharmacy Rx Fill in Year Thousands Number of Enrollees with at least one Retail Pharmacy Rx Fill in Year 3,000 2,500 2,000 1,500 1,000 500 0 Enrollees 2006 2007 2008 2009 2010 2011 2012 2013 1,711,184 2,273,077 2,651,154 2,610,649 2,398,059 2,348,464 2,272,620 1,597,936 NOTE: Year 2013 is limited to the months from January to July. IMS LifeLink PharMetrics Plus™ – U.S. Descriptive Statistics for Enrollees with at least one Retail Pharmacy Rx Fill in Year Median, Mean, and Standard Deviation for Retail Pharmacy Rx Fills Per Enrollee per Year 20 18 16 14 12 10 8 6 4 2 0 2006 2007 2008 2009 2010 2011 2012 2013 5 7 7 7 7 7 7 5 Mean 10.27 13.39 13.62 13.80 13.78 13.37 12.97 7.67 StdDev 14.03 18.01 18.32 18.45 18.21 17.89 17.36 8.93 Median NOTE: Year 2013 is limited to the months from January to July. IMS LifeLink PharMetrics Plus™ – U.S. 25 Most Frequent Retail Pharmacy Rx Fills of LifeLink Members by Drug Group Overall (January 2006 -> July 2013) Top 25 Retail Pharmacy Rx Fills by Drug Group (GPI-2) (decreasing order of frequency) 0 2,000 4,000 6,000 8,000 10,000 12,000 14,000 Thousands 16,000 18,000 36 - ANTIHYPERTENSIVES 58 - ANTIDEPRESSANTS 39 - ANTIHYPERLIPIDEMICS 65 - ANALGESICS - OPIOID 27 - ANTIDIABETICS 49 - ULCER DRUGS 25 - CONTRACEPTIVES 33 - BETA BLOCKERS 44 - ANTIASTHMATIC AND BRONCHODILATOR AGENTS 28 - THYROID AGENTS 90 - DERMATOLOGICALS 37 - DIURETICS 66 - ANALGESICS - ANTI-INFLAMMATORY 72 - ANTICONVULSANTS 01 - PENICILLINS 57 - ANTIANXIETY AGENTS 34 - CALCIUM CHANNEL BLOCKERS 03 - MACROLIDES 61 - ADHD/ANTI-NARCOLEPSY/ANTI-OBESITY/ANOREXIANTS 42 - NASAL AGENTS - SYSTEMIC AND TOPICAL 60 - HYPNOTICS 22 - CORTICOSTEROIDS 43 - COUGH/COLD/ALLERGY 86 - OPHTHALMIC AGENTS 41 - ANTIHISTAMINES IMS LifeLink PharMetrics Plus™ – U.S. 25 Most Frequent Retail Pharmacy Rx Fills of LifeLink Members by Drug Name Overall (January 2006 -> July 2013) Top 25 Retail Pharmacy Rx Fills by Drug Name (GPI-8) (decreasing order of frequency) 0 1000 2000 3000 4000 5000 Thousands 6000 7000 65991702 - HYDROCODONE COMBINATION 28100010 - LEVOTHYROXINE 39400075 - SIMVASTATIN 36100030 - LISINOPRIL 33200030 - METOPROLOL 03400010 - AZITHROMYCIN 25990002 - ETHINYL ESTRADIOL ORAL CONTRACEPTIVE 39400010 - ATORVASTATIN 01200010 - AMOXICILLIN 27250050 - METFORMIN 49270060 - OMEPRAZOLE 37600040 - HYDROCHLOROTHIAZIDE 44201010 - ALBUTEROL 34000003 - AMLODIPINE 57100010 - ALPRAZOLAM 60204080 - ZOLPIDEM 58160070 - SERTRALINE 36994002 - ARB DIURETIC COMBINATION 33200020 - ATENOLOL 58300040 - BUPROPION 42200032 - FLUTICASONE 25992002 - TRIPHASIC OC 44505050 - MONTELUKAST 58160020 - CITALOPRAM 49270025 - ESOMEPRAZOLE IMS LifeLink PharMetrics Plus™ – U.S. Inpatient Hospitalizations by Year Thousands Frequency of Inpatient Hospitalizations by Year 350 300 250 200 150 100 50 0 IMS LifeLink PharMetrics Plus™ – U.S. Primary Discharge Diagnosis Types of Inpatient Hospitalizations Number of Inpatient Hospitalizations by CCS Level I Category of Primary Discharge Dx 0 50 100 150 200 Thousands 250 300 1 - Infectious and parasitic diseases 2 - Neoplasms 3 - Endocrine; nutritional; and metabolic diseases and immunity disorders 4 - Diseases of the blood and blood-forming organs 5 - Mental Illness 6 - Diseases of the nervous system and sense organs 7 - Diseases of the circulatory system 8 - Diseases of the respiratory system 9 - Diseases of the digestive system 10 - Diseases of the genitourinary system 11 - Complications of pregnancy; childbirth; and the puerperium 12 - Diseases of the skin and subcutaneous tissue 13 - Diseases of the musculoskeletal system and connective tissue 14 - Congenital anomalies 15 - Certain conditions originating in the perinatal period 16 - Injury and poisoning 17 - Symptoms; signs; and ill-defined conditions and factors influencing health status 18 - Residual codes; unclassified; all E codes [259. and 260.] IMS LifeLink PharMetrics Plus™ – U.S. 12 Most Frequent Discharge Diagnosis Types of Inpatient Hospitalizations Number of Inpatient Hospitalizations by CCS Level II Category of Primary Discharge Dx (Top 12 CCS Level II Dx Categories in decreasing order of frequency) 0 50 100 150 Thousands 200 7.2 - Diseases of the heart 15.1 - Liveborn [218.] 11.3 - Complications mainly related to pregnancy 11.4 - Indications for care in pregnancy; labor; and delivery 9.6 - Lower gastrointestinal disorders 13.2 - Non-traumatic joint disorders 11.5 - Complications during labor 8.1 - Respiratory infections 16.10 - Complications 10.1 - Diseases of the urinary system 5.8 - Mood disorders [657] 13.3 - Spondylosis; intervertebral disc disorders; other back problems [205.] 863.925 All Other CCS Level II Dx Categories IMS LifeLink PharMetrics Plus™ – U.S. Outpatient Office Encounters by Year Millions Outpatient Office Encounters by Year 25 20 15 10 5 0 IMS LifeLink PharMetrics Plus™ – U.S. Primary Diagnosis Types of Outpatient Office Encounters Number of Outpatient Office Encounters by CCS Level I Category of Primary Discharge Dx 0 5 10 15 20 25 Millions 30 1 - Infectious and parasitic diseases 2 - Neoplasms 3 - Endocrine; nutritional; and metabolic diseases and immunity disorders 4 - Diseases of the blood and blood-forming organs 5 - Mental Illness 6 - Diseases of the nervous system and sense organs 7 - Diseases of the circulatory system 8 - Diseases of the respiratory system 9 - Diseases of the digestive system 10 - Diseases of the genitourinary system 11 - Complications of pregnancy; childbirth; and the puerperium 12 - Diseases of the skin and subcutaneous tissue 13 - Diseases of the musculoskeletal system and connective tissue 14 - Congenital anomalies 15 - Certain conditions originating in the perinatal period 16 - Injury and poisoning 17 - Symptoms; signs; and ill-defined conditions and factors influencing health status 18 - Residual codes; unclassified; all E codes [259. and 260.] IMS LifeLink PharMetrics Plus™ – U.S. 12 Most Frequent Discharge Diagnosis Types of Outpatient Office Encounters Number of Outpatient Office Encounters by CCS Level II Category of Primary Dx (Top 12 CCS Level II Dx Categories in decreasing order of frequency) 0 2 4 6 8 10 Millions 12 17.2 - Factors influencing health care 13.3 - Spondylosis; intervertebral disc disorders; other back problems [205.] 8.1 - Respiratory infections 13.9 - Other bone disease and musculoskeletal deformities [212.] 6.7 - Eye disorders 13.2 - Non-traumatic joint disorders 5.8 - Mood disorders [657] 8.9 - Other upper respiratory disease [134.] 13.8 - Other connective tissue disease [211.] 17.1 - Symptoms; signs; and ill-defined conditions 7.1 - Hypertension 6.8 - Ear conditions 54.578 All Other CCS Level II Dx Categories IMS LifeLink PharMetrics Plus™ – U.S. Outpatient Facility / Hospital Encounter by Year x 100000 Outpatient Facility / Hospital Encounters by Year 45 40 35 30 25 20 15 10 5 0 IMS LifeLink PharMetrics Plus™ – U.S. Primary Diagnoses of Outpatient Facility / Hospital Encounters Number of Outpatient Facility / Hospital Encounters by CCS Level I Category of Primary Dx 0 500 1,000 1,500 2,000 2,500 Thousands 3,000 3,500 1 - Infectious and parasitic diseases 2 - Neoplasms 3 - Endocrine; nutritional; and metabolic diseases and immunity disorders 4 - Diseases of the blood and blood-forming organs 5 - Mental Illness 6 - Diseases of the nervous system and sense organs 7 - Diseases of the circulatory system 8 - Diseases of the respiratory system 9 - Diseases of the digestive system 10 - Diseases of the genitourinary system 11 - Complications of pregnancy; childbirth; and the puerperium 12 - Diseases of the skin and subcutaneous tissue 13 - Diseases of the musculoskeletal system and connective tissue 14 - Congenital anomalies 15 - Certain conditions originating in the perinatal period 16 - Injury and poisoning 17 - Symptoms; signs; and ill-defined conditions and factors influencing health status 18 - Residual codes; unclassified; all E codes [259. and 260.] IMS LifeLink PharMetrics Plus™ – U.S. 12 Most Frequent Primary Diagnoses of Outpatient Facility / Hospital Encounters Number of Outpatient Facility / Hospital Encounters by CCS Level II Category of Primary Discharge Dx (Top 12 CCS Level II Dx Categories in decreasing order of frequency) 0 500 1,000 1,500 Thousands 2,000 17.2 - Factors influencing health care 17.1 - Symptoms; signs; and ill-defined conditions 7.2 - Diseases of the heart 10.1 - Diseases of the urinary system 8.1 - Respiratory infections 13.3 - Spondylosis; intervertebral disc disorders; other back problems [205.] 16.7 - Sprains and strains [232.] 13.2 - Non-traumatic joint disorders 10.3 - Diseases of female genital organs 13.8 - Other connective tissue disease [211.] 16.6 - Open wounds 6.7 - Eye disorders 13,858.122 All Other CCS Level II Dx Categories