AP BIOLOGY (Secondary) ESSENTIAL UNIT 4 (E04) (Cellular Communication) (July 2013) Unit Statement: In this unit student will explore the nature of cell communication, the structure and function of the cell membrane, diffusion, facilitated diffusion, active transport, osmosis and how these processes allow the immune, nervous, endocrine, muscular and circulatory systems to transmit and receive information. Overview – Cellular Communication (3 Weeks) ● Cell Communication ● Cell membranes and Transport ● Immune System ● Nervous System ● Muscular System ● Endocrine system ● Circulatory System Essential Outcomes: (must be assessed for mastery) 1. The Student Will use representations and models to pose scientific questions about the properties of cell membranes and selective permeability based on molecular structure. 2. TSW construct models that connect the movement of molecules across membranes with membrane structure and function. 3. TSW explain how internal membranes and organelles contribute to cell functions. 4. TSW create representations and models to describe specific and nonspecific immune responses in plants and animals. 5. TSW describe basic chemical processes and generate scientific questions involving cell communication shared across evolutionary lines of descent. 6. TSW construct explanations and/or create representations of cell communication through cell-to-cell direct contact or from a distance through chemical signaling. 7. TSW use representation(s) and appropriate models to justify, based on scientific evidence, and describe the key elements of signal transduction pathways by which a signal is converted to and alters cellular response. 8. TSW construct an explanation of how certain drugs affect signal reception and, consequently, signal transduction pathways. 25 QSI AP BIOLOGY E04 SEC Copyright © 1988-2013 9. TSW analyze data that indicate how organisms exchange information in response to internal changes and external cues, and which can change behavior. 10. TSW construct an explanation, based on scientific theories and models and create a visual representation of complex nervous systems to describe/explain how these systems detect external and internal signals, transmit and integrate information, and produce responses. Suggested Chapters (Campbell): ● ● ● ● ● ● ● ● 7 - Membrane Structure and Function 11 - Cell Communication 42 - Circulation and Gas Exchange 43 - Immune System 45 - Hormones and the Endocrine System 48 - Neurons, Synapses, and Signaling 49 - Nervous Systems 50 - Sensory and Motor Mechanisms Suggested Chapters (Starr): ● ● ● ● ● ● ● 5 – A Closer Look at Cell Membranes 33 – Neural Control 34 – Sensory Perception 35 – Endocrine Control 36 – Structural Support and Movement 37 – Circulatory System 38 – Immunity Suggested Overview of Lecture and Discussion Topics: 1. 2. 3. 4. 5. 6. 7. Membrane structure and function. Cell communication steps and ubiquitous nature. Functioning of immune system and ELISA Assay background. Neuron structure and functioning. Nature of sensory mechanisms. Sliding filament theory. Student presentations are dispersed between above topics. Suggested Activities: 1. Science project a. Open inquiry into the shape and function of specialized cells of the immune, endocrine, sensory mechanisms. b. Research on topic. At least two scientific journal articles must be used. c. Students are required to construct a 3-D model of their specialized cell. d. Provide explanation of how that cell communicates with the rest of the body. e. Describe a disease state other than cancer that can affect this cell. f. Presentation of material to class members. 26 QSI AP BIOLOGY E04 SEC Copyright © 1988-2013 2. Diffusion and Osmosis: AP Investigation 4 (Smartscience Labs: Membrane Diffusion, Osmosis, Onion Osmosis) 3. Activity of membrane modeling- cut and paste. 4. Membrane Channels Simulation (http://phet.colorado.edu/en/simulation/membrane-channels) 5. Neuron Simulation (http://phet.colorado.edu/en/simulation/neuron) 6. Manipulation of models of neuron signaling and action potential computations. 7. Models of cell communication with insulin. Technology Links: ● ● ● ● Biosignaling: Cell Communication and Signaling is an open access online journal. Learn Genetics: The Inside Story of Cell Communication The University of Utah’s Genetic Science Learning Center. Learn Genetics: A Real Example of Cell Communication: A Youtube video. The Biology Project: Cell Signalling Problem Set Suggested Rubric: The students will be evaluated for each unit according to the following rubric: Above Mastery (A) Mastery (B) In Progress (P) Multiple Choice Unit Exam (s) 93% or better 86% - 92.9% 85.9% or lower Free Response Question 8 or better on the unique rubric written for each question 5 – 7 on the unique rubric written for each question 4 or below on the unique rubric written for each question Laboratory Experiment (s) Laboratory experiments were performed, data collected and analyzed, and written in a concise, clear, and accurate manner with graphics/diagrams neat and complete and appropriate terminology according to teacher’s instructions. If formal lab is requested – use Lab Report Rubric Laboratory experiments were performed, data collected and analyzed, and written in a concise, clear, and accurate manner with graphics/diagrams relatively neat and complete and generally appropriate terminology according to teacher’s instructions. If Laboratory experiments were performed and written in a concise, clear, and accurate manner with graphics/diagrams lacking in neatness and completeness and some appropriate terminology according to teacher’s instructions. If formal lab is requested – use 27 QSI AP BIOLOGY E04 SEC Copyright © 1988-2013 Study Guide, Worksheets, Homework, and Notebook Study Guides, Worksheets, and Notebooks are consistently up to date, neat, and accurate. Information can be easily accessed. formal lab is requested – use Lab Report Rubric Lab Report Rubric. Study Guides, Worksheets, and Notebooks are relatively up to date, neat, and accurate Study Guides, Worksheets, and Notebooks are not up to date, neat, and accurate. Information can be somewhat easily accessed. It is difficult to access information. If a student falls within the “P” range the following steps will be taken to complete the outstanding unit: 1. The student will be automatically be assigned to the after-school homework tutorial for the duration of the next unit or until mastery of the outstanding unit, whichever comes first. In the after school homework tutorial, the following steps should be taken: a. First, the student must complete all unfinished work for the outstanding unit. b. Second, the student will use his/her time to study the necessary material and ask for additional help if necessary. c. Third, student will retest if necessary. If the student masters the subject matter the second time around with an 86% or better and finished all past work with at least a ‘B’ according to the rubric, he/she will earn a ‘B’. 2. If the student doesn’t master the outstanding unit according to the rubric during current unit, the unit will be assessed with an H, W, or D. If a W is awarded then no credit for that unit may be obtained in the current calendar school year, but the student still may participate in the AP exam in May. 28 QSI AP BIOLOGY E04 SEC Copyright © 1988-2013