Eldra Solomon Linda Berg Diana W. Martin www.cengage.com/biology/solomon Chapter 1 A View of Life Albia Dugger • Miami Dade College A View of Life: H1N1 H1N1 • H1N1 influenza attracted global attention in April 2009, when more than 200 countries around the world reported confirmed cases within a few months • Pandemics such as H1N1 affect many aspects of life, including global economy, travel, tourism, and education Biology • Biologists are making new discoveries that affect every aspect of our lives, including health, food, safety, relationships with humans and other organisms, and the environment of our planet • biology • The science of life 1.1 THREE BASIC THEMES LEARNING OBJECTIVE: • Describe three basic themes of biology Three Basic Themes of Biology • Evolution • Evolution results in populations changing over time • Explains how the ancestry of organisms can be traced back to earlier forms of life • Information transfer • Information must be transmitted within cells, among cells, among organisms, and from one generation to the next • Energy transfer • Life requires continuous input of energy from the sun KEY CONCEPTS 1.1 • Basic themes of biology include evolution, information transfer, and energy transfer 1.2 CHARACTERISTICS OF LIFE LEARNING OBJECTIVE: • Distinguish between living and nonliving things by describing the features that characterize living organisms Organisms are Composed of Cells • cell theory • A fundamental unifying concept of biology • Every living organism is composed of one or more cells • New cells are formed only by division of previously existing cells • Simple, unicellular life-forms consist of a single cell • Complex, multicellular organisms depend on coordinated functions of cells that are organized to form tissues, organs, and organ systems Unicellular and Multicellular Life-Forms • Paramecium (a) Unicellular organisms consist of one intricate cell that performs all the functions essential to life. Ciliates, such as this Paramecium , move about by beating their hairlike cilia. • African buffalo, plants (b) Multicellular organisms, such as this African buffalo (Syncerus caffer) and the plants on which it grazes, may consist of billions of cells specialized to perform specific functions. Cell Structure • A plasma membrane protects the cell and regulates passage of materials between the cell and its environment • Specialized molecules – usually deoxyribonucleic acid (DNA) – contain genetic instructions and transmit genetic information • Internal structures (organelles) are specialized to perform specific functions Two Types of Cells • prokaryotic cells • Exclusive to bacteria and archaea • Structurally simple; they do not have a nucleus or other membrane-enclosed organelles • eukaryotic cells • Typically contain a variety of organelles enclosed by membranes, including a nucleus, which houses DNA Organisms Grow and Develop • Biological growth involves an increase in size of individual cells of an organism, in number of cells, or in both • Some organisms (e.g. trees) grow throughout their lives • Many animals have a growth period that ends at adult size • Development includes all changes during an organism’s life • Example: A human develops from a fertilized egg into a multicellular organism with structures and body form adapted to specific functions Organisms Regulate Their Metabolic Processes • Metabolism includes all chemical activities that take place in an organism, including chemical reactions essential to nutrition, growth and repair, and conversion of energy • Homeostatic mechanisms carefully regulate metabolic processes to maintain an appropriate, balanced internal environment (homeostasis) • Example: Regulation of blood sugar (glucose) Organisms Respond to Stimuli • Organisms respond to physical or chemical changes in their external or internal environment (stimuli) • Responses typically involve movement • Unicellular organisms may move by slow oozing of the cell (amoeboid movement), by beating tiny, hairlike extensions of the cell (cilia) or longer structures (flagella) Flagella • Bacteria equipped with flagella for locomotion • Helicobacter pylori have been linked to stomach ulcers Organisms Respond to Stimuli (cont.) • Most animals move by contracting muscles • Complex animals have highly specialized cells that respond to specific types of stimuli, such as light • Plants respond to light, gravity, water, touch, and other stimuli Plants Respond to Stimuli Fig. 1-3a, p. 4 Organisms Reproduce • asexual reproduction • Offspring have the same genes as the single parent • Variation occurs only by mutations • sexual reproduction • Offspring are produced by fusion of egg and sperm • Genes are typically contributed by two parents Asexual and Sexual Reproduction Fig. 1-4, p. 5 Populations Evolve and Become Adapted to the Environment • As populations evolve, they become adapted to their environment • Adaptations may be structural, physiological, biochemical, behavioral, or a combination of all four • adaptations • Inherited characteristics that enhance an organism’s ability to survive in a particular environment Adaptations • Burchell’s zebras (1) are behaviorally adapted to watch for predators, (2) have stripes for visual protection against predators, (3) have stomachs adapted to coarse grass (enlarged cecum) Fig. 1-5, p. 5 KEY CONCEPTS 1.2 • Characteristics of life include: • cellular structure • growth and development • self-regulated metabolism • response to stimuli • reproduction 1.3 LEVELS OF BIOLOGICAL ORGANIZATION LEARNING OBJECTIVE: • Construct a hierarchy of biological organization, including levels characteristic of individual organisms and levels characteristic of ecological systems Organisms Have Several Levels of Organization • Atoms and molecules form cells • Cells associate to form tissues • Tissues organize into functional structures (organs) • In animals, major biological functions are performed by a coordinated group of tissues and organs (organ system) • Organ systems function together to make up a complex, multicellular organism Several Levels of Ecological Organization Can Be Identified • population • All members of one species living in the same geographic area at the same time • community • Populations of various types of organisms living and interacting with one another in a particular area • ecosystem • A community together with its nonliving environment Levels of Organization (cont.) • All of Earth’s ecosystems together are known as the biosphere • The study of how organisms relate to one another and to their physical environment is called ecology Hierarchy of Biological Organization Organism Organ systems work together in a functional organism. Organ system (e.g., skeletal system) Tissues and organs make up organ systems. Population A population consists of organisms of the same species. Organism Population Organ system Organ (e. g., bone) Tissues form organs. Community The populations of different species that populate the same area make up a community. Organ Tissue (e.g., bone tissue) Cells associate to form tissues. Cellular level Atoms and molecules make up the cytoplasm and form organelles, such as the nucleus and mitochondria (the site of many energy transformations). Organelles perform various functions of the cell. Chemical level Atoms join to form molecules. Macromolecules are large molecules such as proteins and DNA. Community Tissue Bone cells Nucleus Cell Organelle Ecosystem Macromolecule Biosphere Molecule Oxygen atom Hydrogen atoms Water Ecosystem A community together with the nonliving environment forms an ecosystem. Biosphere Earth and all of its communities constitute the biosphere. Stepped Art Fig. 1-6, p. 7 KEY CONCEPTS 1.3 • Biological organization includes chemical, cell, tissue, organ, organ system, and organism levels • Ecological organization includes population, community, ecosystem, and biosphere levels 1.4 INFORMATION TRANSFER LEARNING OBJECTIVE: • Summarize the importance of information transfer within and between living systems, giving specific examples DNA Transmits Information from One Generation to the Next • A DNA molecule consists of two chains of atoms twisted into a helix • Each chain is made up of a sequence of chemical subunits called nucleotides DNA • DNA is the hereditary material that transmits information from one generation to the next • The sequence of nucleotides makes up the genetic code Fig. 1-7, p. 8 Information is Transmitted by Chemical and Electrical Signals • Genes control development and function of every organism • The DNA that makes up genes contains instructions for making all the proteins required by the organism • proteins • Large molecules important in determining the structure and function of cells and tissues Communication Between Cells • Cells use proteins and other molecules to communicate with one another • Hormones and other chemical messengers signal cells in distant organs to secrete a required substance or change a metabolic activity • Animals’ nervous systems transmit information by electrical impulses and chemical compounds (neurotransmitters) KEY CONCEPTS 1.4 • Information transfer includes: • DNA transfer of information from one generation to the next • Chemical and electrical signals within and among the cells of every organism • Chemicals, visual displays, and sounds that allow organisms to communicate with one another and to interact with their environment 1.5 THE ENERGY OF LIFE LEARNING OBJECTIVE: • Summarize the flow of energy through ecosystems and contrast the roles of producers, consumers, and decomposers Energy and Metabolism • Life depends on continuous input of energy from the sun • Whenever energy is used to perform biological work, some is converted to heat and dispersed into the environment • All energy transformations and chemical processes within an organism are referred to as its metabolism Cellular Respiration • All cells require nutrients that contain energy • During cellular respiration, cells capture energy released by nutrient molecules through a series of carefully regulated chemical reactions • Cells use this energy to do work, including synthesis of new cell components Energy in Ecosystems • Ecosystems also depend on continuous energy input • Ecosystems include three types of organisms (producers, consumers, decomposers) and their physical environment • There is a one-way flow of energy through ecosystems • Organisms can neither create energy nor use it with complete efficiency • During every energy transaction, some energy disperses into the environment as heat The Producers • Plants, algae, and some bacteria are producers (autotrophs) that produce their own food from simple raw materials • Most producers use sunlight as energy for photosynthesis, which transforms light energy into chemical energy stored in chemical bonds of food molecules • Photosynthesis synthesizes food molecules such as glucose (sugar) from carbon dioxide and water, and releases oxygen: carbon dioxide + water + light → glucose + oxygen The Consumers • Animals are consumers (heterotrophs) that obtain energy by breaking down food molecules produced in photosynthesis • Primary consumers eat producers; secondary consumers eat primary consumers • Chemical bonds are broken in the process of cellular respiration, and stored energy is made available: glucose + oxygen → carbon dioxide + water + energy The Decomposers • Most bacteria and fungi are decomposers, heterotrophs that obtain nutrients by breaking down nonliving organic material such as wastes, dead leaves and branches, and bodies of dead organisms • In the process of obtaining energy, decomposers make the components of these materials available for reuse Energy Flow Within and Among Organisms Light energy Photosynthesis captures light energy Oxygen Energy stored in glucose and other nutrients Carbon dioxide and water Oxygen Energy Cellular respiration releases energy stored in glucose molecules Synthesis of Other Life Activities needed • Homeostasis • Growth and molecules and structures development • Reproduction • Movement of materials in and out of cells • Movement of body Fig. 1-8, p. 9 Energy Flow Through the Biosphere • During every energy transaction, some energy is lost to biological systems, dispersing into the environment as heat Light energy Heat Heat Food Heat Primary consumer (caterpillar) Secondary consumer (robin) Heat Producer (plant) Plant litter, wastes Soil Dead bodies Decomposers (bacteria, fungi) Fig. 1-9, p. 10 1.6 THE BASIC CONCEPTS OF BIOLOGY LEARNING OBJECTIVES: • Demonstrate the binomial system of nomenclature using specific examples, and classify an organism in its domain, kingdom, phylum, class, order, family, genus, and species • Identify the three domains and the kingdoms of living organisms, and give examples of organisms in each group • Give a brief overview of the scientific theory of evolution and explain why it is the principal unifying concept in biology • Apply the theory of natural selection to any given adaptation and suggest a logical explanation of how it may have evolved Evolution • evolution • Process by which populations of organisms change over time • Involves passing genes for new traits from one generation to another, leading to differences in populations Biologists Use a Binomial System for Naming Organisms • Systematics is the field of biology that studies the diversity of organisms and their relationships • Taxonomy, is the science of naming and classifying organisms Binomial System • The binomial system of nomenclature is used to name each species, it is called such because each species has a two-part name • The first part of the name is the genus • The second part, the specific epithet, designates a particular species in that genus • Example: The domestic dog, Canis familiaris (or C. familiaris), and timber wolf, Canis lupus (C. lupus), are in the same genus Species and Genus • A species is a group of organisms with similar structure, function, and behavior • Closely related species are grouped into a genus (genera) Taxonomic Classification is Hierarchical • Related genera are grouped in a family • Families are grouped into orders, orders into classes, and classes into phyla (phylum) • Phyla are assigned to kingdoms, and kingdoms are grouped in domains • Each level is a taxon (taxa) Classification of the Cat, Human, and White Oak Tree Table 1-1, p. 11 DOMAIN Eukarya KINGDOM Animalia PHYLUM Chordata CLASS Mammalia ORDER Primates FAMILY Pongidae GENUS Pan SPECIES Pan troglodytes Fig. 1-10, p. 12 Three Domains • Most biologists assign organisms to three domains and several kingdoms • There are two domains of organisms with prokaryotic cells (prokaryotes): Bacteria and Archaea • Kingdom Archaea corresponds to domain Archaea • Kingdom Bacteria corresponds to domain Bacteria • All other organisms belong to the domain Eukarya Domain Eukarya • Organisms with eukaryotic cells (eukaryotes) are classified in domain Eukarya • Protists (including five “supergroups”) are unicellular, colonial, or simple multicellular eukaryotic organisms • Kingdom Plantae (plants) are complex multicellular organisms adapted for photosynthesis • Kingdom Fungi (yeasts, mildews, molds, and mushrooms) do not photosynthesize – they obtain nutrients by secreting digestive enzymes into food and absorbing it • Kingdom Animalia includes complex multicellular organisms that obtain nutrition by eating other organisms Three Domains of Life Domain Bacteria Domain Archaea (a) The large, rod-shaped bacterium Bacillus anthracis, a member of domain Bacteria, causes anthrax, a disease of cattle and sheep that can infect humans. (b) These archaea (Methanosarcina mazei), members of the domain Archaea, produce methane. Bacteria Archaea Domain Eukarya (c) These unicellular protozoa (Tetrahymena) are classified in one of the protist groups. Protists Common ancestor of all organisms (d) Plants include many beautiful and diverse forms, such as the lady’s slipper (Phragmipedium caricinum). (e) Among the fiercest animals, lions (Panthera leo) are also among the most sociable. The largest of the big cats, lions live in prides (groups). Plants Animals (f) Mushrooms, such as these fly agaric mushrooms (Amanita muscaria), are fungi. The fly agaric is poisonous and causes delirium, raving, and profuse sweating when ingested. Fungi Stepped Art Fig. 1-11, p. 13 Species Adapt in Response to Changes in Their Environment • Every organism is the product of numerous interactions between environmental conditions and genes inherited from its ancestors • If all individuals of a species were exactly alike, any change in the environment might be disastrous to all, and the species would become extinct • Adaptations to changes in the environment occur as a result of evolutionary processes that take place over time and involve many generations Natural Selection: An Important Evolutionary Mechanism • Charles Darwin and Alfred Wallace proposed a theory of evolution and suggested a mechanism: natural selection • Darwin’s book, On the Origin of Species by Natural Selection (1859), supported his hypothesis that present forms of life descended, with modifications, from previously existing forms Darwin’s Four Observations • Darwin based his theory on four observations: 1. Individual members of a species vary from one another 2. Organisms produce many more offspring than will survive to reproduce 3. More individuals are produced than the environment can support, so organisms must compete for necessary, but limited, resources; also, some are killed by predators, disease organisms, or unfavorable natural conditions 4. Individuals with characteristics that enable them to withstand prevailing environmental conditions and challenges are more likely to survive and reproduce Adaptation • Survivors that reproduce pass their adaptations for survival on to their offspring • The best-adapted individuals leave, on average, more offspring than other individuals (differential reproduction) • The environment selects the best-adapted organisms of a population for survival • Adaptation involves changes in populations, not individuals Mutation and Variation • Most variations among individuals result from different varieties of genes that code for each characteristic • The ultimate source of these variations is random mutations (chemical or physical changes in DNA that can be inherited) • Mutations modify genes and provide the raw material for evolution Populations Evolve Due to Selective Pressures from Environmental Changes • All genes in a population make up its gene pool (a reservoir of genetic variation) • Natural selection acts on individuals within a population • Selection favors individuals with genes for traits that allow them to respond effectively to environmental pressure; these individuals are most likely to survive and produce offspring • Over time, members of a population become better adapted to their environment and less like their ancestors – new species may evolve 1.7 THE PROCESS OF SCIENCE LEARNING OBJECTIVES: • Design a study to test a given hypothesis, using the procedure and terminology of the scientific method • Compare the reductionist and systems approaches to biological research Process of Science • Science is a way of thinking, and a method of investigating, the natural world in a systematic manner • The process of science is investigative, dynamic, and often controversial – observations, questions, and experimental design depend on the creativity of the individual scientist • Science is influenced by cultural, social, historical, and technological contexts, so the process changes over time Scientific Method • The scientific method involves a series of ordered steps: • Make careful observations • Ask critical questions and develop hypotheses • Make predictions that can be tested by making further observations or by performing experiments • Gather information (data) that can be analyzed • Interpret the results of experiments and draw conclusions Careful Observations and Chance • 1928: Alexander Fleming did not set out to discover penicillin • When a blue mold invaded one of his bacterial cultures, he noticed that the contaminated area was surrounded by a zone where bacterial colonies did not grow • Fleming benefited from chance, but his mind was prepared to make observations and formulate critical questions A Hypothesis is a Testable Statement • A hypothesis is a tentative explanation for observations or phenomena • A good hypothesis has three characteristics: 1. It is reasonably consistent with well-established facts 2. It is capable of being tested; and test results should be repeatable by independent observers 3. It is falsifiable (can be proven false) A Falsifiable Hypothesis Can Be Tested • A well-stated hypothesis can be tested • If no evidence is found to support it, the hypothesis is rejected • The hypothesis can be shown to be false • A hypothesis can be supported by data, but it can’t really be proven true Models Are Important in Developing and Testing Hypotheses • Hypotheses may be derived from models that scientists develop to provide a comprehensive explanation for a large number of observations • Examples: Model of the structure of DNA; model of the structure of the plasma membrane • The best design for an experiment can sometimes be established by performing computer simulations Many Predictions can be Tested by Experiment • Scientists make predictions (deductive, logical consequences of a hypothesis) that can be tested by experiments • Some predictions can be tested by controlled experiments in which an experimental group differs from a control group only with respect to the variable being studied Key Experiment • Scientists observed that the nucleus was the most prominent part of the cell, and predicted that cells would be adversely affected if they lost their nuclei • Experiment: • Experimental group: Nucleus was removed • Control group: A microloop was inserted into the cell to simulate removal, but the nucleus was left inside • Result: The control group lived; the experimental group died Key Experiment (cont.) Amoeba dies (a) Experimental group. When its nucleus is surgically removed with a microloop, the amoeba dies. Fig. 1-17a, p. 18 Amoeba lives (b) Control group. A control amoeba subjected to similar surgical procedures (including insertion of a microloop), but without actual removal of the nucleus, does not die. Fig. 1-17b, p. 18 Researchers Must Avoid Bias • In scientific studies, researchers must try to avoid bias or preconceived ideas of what should happen • In a double-blind study neither patient nor physician knows who gets an experimental drug and who gets a placebo • Not all experiments can be so neatly designed – it is often difficult to establish appropriate controls Scientists Interpret Results and Make Conclusions • Scientists gather data in an experiment, interpret results, and draw conclusions from them • In the amoeba experiment, investigators concluded that data supported the hypothesis that the nucleus is essential for the survival of the cell • Results that falsify a hypothesis also may be valuable and may lead to new hypotheses Sampling Error and Repeatability • One reason for inaccurate conclusions is sampling error • Not all cases can be observed or tested • If the sample is too small, it may not be representative because of random factors • Scientists try to state that any specific conclusion has a certain statistical probability of being correct • Experiments must be repeatable by other scientists Statistical Probability Fig. 1-19, p. 21 Curtain Marbles Single selection produces Assumption 100% blue Actual ratio 20% blue 80% white (a) Taking a single selection can result in sampling error. If the only marble selected is blue, we might assume all the marbles are blue. Fig. 1-19a, p. 21 Curtain Marbles Multiple selections produce Assumption 30% blue Actual ratio 70% white 20% blue 80% white (b) The greater the number of selections we take of an unknown, the more likely we can make valid assumptions about it. Fig. 1-19b, p. 21 A Theory is Supported by Tested Hypotheses • A scientific theory is an integrated explanation of some aspect of the natural world, based on a number of hypotheses, each supported by consistent results from many observations or experiments • By showing relationships among classes of facts, a scientific theory clarifies our understanding of the natural world Paradigm Shifts Allow New Discoveries • A paradigm is a set of assumptions or concepts that constitute a way of thinking about reality • As new facts are discovered, biologists have to make paradigm shifts – they change their view of reality to accommodate new knowledge • Systems biology is a field of biology that builds on information provided and integrates the different levels of information Science Has Ethical Dimensions • Honesty is particularly important in science – science tends to correct itself through consistent use of the scientific process • Scientists face many societal and political issues surrounding areas such as genetic research, stem cell research, cloning, and human and animal experimentation • Human genome research raises ethical concerns about the privacy of genetic information; and the ethical, legal, and social implications of its findings KEY CONCEPTS 1.7 • Biologists ask questions, develop hypotheses, make predictions, and collect data by careful observation and experiment • Based on their results, they come to conclusions