Stages of Mitosis
Mitosis (M Phase)
The M Phase consists of:
• Mitosis and Cytokinesis
Four Stages of Mitosis:
Prophase
Metaphase
Anaphase
Telophase
Late Interphase
Centrosome (with centriole pair)
Nuclear membrane
Chromatin
Nucleolus
Late Interphase
• Cell is preparing for
division.
• Chromatin (relaxed
form of DNA) has
been replicated.
• Nuclear membrane
and nucleolus are
still visible.
Early & Late Prophase
Spindle apparatus
Chromosomes made of
two sister chromatids
Nuclear membrane
(disappearing)
Centromere (where sister
chromatids attach)
Early & Late Prophase
• Chromatin condenses into chromosomes.
• Nuclear membrane & nucleolus disappear.
• Spindle apparatus forms.
Metaphase
Centrosome
Equator or metaphase plate
Centromere
Metaphase
• Chromosomes line
up at imaginary line
in the middle of the
cell.
• Spindle apparatus is
attached to the
centromeres.
Anaphase
Centrosome
Shortening spindle apparatus
Anaphase
• Spindle apparatus
shortens and
chromatids are
pulled apart.
Telophase & Cytokinesis
Chromosomes relaxing
Animal cell “cleavage furrow”
OR
Plant cell “cell plate”
Nuclear membrane reforming
Telophase & Cytokinesis
• Chromosomes arrive
at opposite ends of
the cell and begin to
relax.
• Nuclear membranes
reform and nucleoli
reappear.
• Spindle apparatus
disassembles.
Telophase & Cytokinesis
• Begins towards the
end of mitosis.
• Microtubules help
organelles and
cytoplasm divide.
What’s the end product?
• Two identical daughter cells ready to start the
cycle again… or not.
• Some cells (like your nerve and muscle cells)
do not undergo division.
• For those that do (your skin and the lining of
your intestinal tract) how would you know
how quickly division takes place?
RE-identify the stages of Mitosis