VIROLOGY
Claude MUVUNYI M.D, Ph.D.
Head of Microbiology Unit/NRL
RBC
VIROLOGY
 Module: INFECTION II
 Definition: Study of viral structure and behavior, HOW
disease occurs and WHY?
 Course Intent: Undergraduate students (Medicine and
Pharmacy). All aspects of virology will be covered including
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Viruses Structure,
replication and expression mechanisms,
Pathogenesis and epidemiology
host defenses
Methods for diagnosis
VIROLOGY
Prerequisites:
• Cell and Molecular Biology: This is an absolute requirement!! If you
don’t have a solid understanding of cell structure and the processes
of transcription and translation, drop the class now.
• Microbiology: Also listed as a requirement, but I’ll let it slide if
you’ve had #3.
• Genetics: recommended, but not required
• Organic chemistry and biochemistry are very helpful, but not
required
• Immunology is also helpful, but not required
VIROLOGY
 Required text:
• E.K. Wagner and M.J. Hewlett, "Basic Virology", 2nd Ed. Blackwell Science,
2004.
• Virology: Principles and Applications. 2007. Authors: Carter and Saunders
(Wiley Publishing)
 Recommended reference texts:
• S.J. Flint et al., "Principles of Virology: Molecular Biology, Pathogenesis, and
Control", ASM Press, 2000.
 Internet resources: Animations and other materials can be found at
http://www.blackwellpublishing.com/Wagner/default.asp.
 Class notes: You will have access to all lecture material Syllabus
• Power points slides
• syllabus as hard and soft files.
VIROLOGY
Requirement to sit for Exams: 85 % class
attendance
Grade Determination: The grade in this class is
determined by the following:
• Lecture Exam (multiple choice or short answers) –
70%
• Presentation or Assay (TP): 30%
VIROLOGY
 Course Outcomes: At the end of the course, students
should be able to:
• Diagram replication strategies for the major classes of viruses
• Explain different strategies for viral gene expression, infection
patterns and pathogenesis
• Explain the differences between different classes of viruses
• Identify reliable sources of information about epidemics,
emerging viruses, and vaccination programs
• Describe prevention and treatment strategies associated with
various viral infections
VIROLOGY
 SEQUENCE OF LECTURE MATERIAL
• SECTION 1: Viral definition, structures and classification
• SECTION 2: Replication of the virus
• SECTION 3: Viral Pathogenesis
• SECTION 4: Viral diseases and Epidemiology
• SECTION 5: Means of viral infection diagnosis
VIROLOGY
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