An-Najah National University
College of Medicine and Health Sciences
Virology 7105326
Second Semester 2015-2016
Course Outline
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Course credit hours: 2 Theoretical credit hours.
Student load: 2 hours a week.
Prerequisite course: General Microbiology.
Instructor:
Alaeddin Abu Zant, Ph.D Microbiology and Immunology
Email: aladdin_abuzant@najah.edu
Text Books:
1- Jawetz, Melnick & Adelberg's Medical Microbiology 27th Ed, 2016
2- Greenwood David et al. Medical Microbiology 17th Ed 2007
3- Warren Levinson. Review of Medical Microbiology and Immunology, 12th edition 2012
4- Lippincott's Illustrated Reviews: Microbiology, 2007, 2nd ed., Richard A. Harvey; Pamela C. Champe
Bruce D. Fisher, Lippincott Williams & Wilkins, ISBN 0-7817-8215-5
Additional material that can be used:
Internet resources (www.cdc.gov)
Published scientific papers and reviews
Course aims and description:
This course covers the most important and advanced knowledge about medically important viruses in
terms of their epidemiology, pathogenesis, clinical symptoms and prevention. In addition, it provides the
students with the major concepts about viral structure, classification, replication, anti-viral agents, viral
vaccines and the basics of viral diagnostic methods.
1
Intended learning outcomes (ILOs)
A- Knowledge and understanding:
a.1- Recognize the basics of the science of virology
a.2- Compare and contrast different virus families
a.3- Describe the replication strategies of DNA and RNA viruses
a.4- Explain the epidemiology and pathogenesis of viral diseases and the virus-host relationship
a.5- Identify strategies to diagnose, prevent and combat human viral diseases
a.6- Recognize and list human oncogenic viruses
a.7- Identify non-conventional infectious agents and their pathogeneses
B- Intellectual skills:
b.1- Correlate between clinical features of eventual viral diseases.
b.2- Choose and assess appropriate isolation methods and identification of different viruses.
b.3- Discuss and evaluate viral application in medicine and biotechnology.
b.4- Analyze critically research papers in Virology.
C- General and transferable skills:
c.1- Search Internet database for new updates in virology.
c.2- Independent learning
c.3- Work co-operatively in a team.
c.4- Organize and present scientific data in oral and written manner using English language
MAIN TOPICS OF THE COURSE
I- INTRODUCTION TO VIROLOGY
II- BASIC VIROLOGY
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Structure
Replication
Genetics
Pathogenesis
Classification
Vaccines
Antiviral agents
2
III-MEDICAL VIROLOGY
A-DNA VIRUSES
1-Non-enveloped:
 Papovaviridae
 Adenoviridae
 Parvoviridae
2- Enveloped
 Herpesviridae
 Poxviridae
 Hepadnaviridae
B-RNA VIRUSES
SINGLE-STRANDED RNA VIRUSES
1-Single-stranded RNA viruses (Positive Polarity)
A-Non-enveloped
 Picornaviridae
 Calciviridae
 Astroviridae
B-Enveloped
 Togaviridae
 Flaviviridae
 Retroviridae
 Coronaviridae
2-Single-stranded RNA viruses (Negative Polarity)
A-Enveloped
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Rhabdoviridae
Paramyxoviridae
Paramyxovirinae
Pneumovirinae
Orthomyxoviridae
Filoviridae
Bunyaviridae
Arenaviridae
DOUBLE-STRANDED RNA VIRUSES
 Reoviridae
3
C- Unconventional Infectious Agents
 Viroids
 Virusoids
 Prions
Teaching and learning methods
Tool
Purpose
Assessment method
ILOS
Lectures
To explain the theoretical
Written exams,
a.1, a.2, a.3, a.4, a.5, a.6,
knowledge for each topic.
Homework, Quizzes.
a.7.
Tutorials and
To explain the practical knowledge
Objective testing,
Documentary
for each topic.
Short answers,
films
c.1, c.2, c.3, c.4.
Problem-solving.
Case study and
To answer the questions of the
group discussion
students and evaluates their
Active participation.
b.1, b.2, b.3, b.4
c.1, c.2, c.3, c.4.
knowledge.
Presentations
To encourage students discuss,
b.1, b.2, b.3, b.4
analyze and criticize data and
Rubric evaluation.
c.1, c.2, c.3, c.4.
others works.
Course Policies
Class attendance (Participation)
Case Presentation
Grading
Tool
%
Assessment Method
ILOS
First Exam
25
Second Exam
25
Objective essays question and
a1-7,
Final Exam
50
case study
b1-4.
Total
100
Rubric evaluation
b1-4,
Case study and
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seminars
c1-4.
4