4. (StI-HUGE) HUMAN GENETICS
STUDY PROGRAMME
Integrated studies of dentistry
DEPARTMENT
For general knowledge subjects
NAME OF SUBJECT
HUMANA GENETIKA
Compulsory
STATUS OF THE SUBJECT
Condition:
Year of studies
first
none
Winter term (No.of the lessons
per week
Summer term (No.of the
lessons per week)
Lectures
Exercises
Lectures.
Exercises
3
2
-
-
No.of tests
No.of
seminars
No.of
POINT
S
3
-
5,5
Methods of conducting teaching Lectures and exercises
GOA
L
Purpose of this subject is to teach students everything about human genome as well as genetical machanisms of hereditary
diseases. Students will be able to use different sources of information and learn about technological achievements in
exploration of human genome. They will also learn about transferring genetical information.
Students will be able to use basic genetic notions, learn about structure of chromatine, organisation of
chromosome. They will apply Mendel's laws and understand gene interactions.they will be able to predict
Knowledg
machanisms of inheriting and be able to precisely construct family trees based on the given data. They will
e
understand mechanisms of mutation and DNA reparation. They will understand basic techniques of molecular
genetics and principles of gentic therapy.
PURPOSE
Skills
After pre-exam and exam obligations student will be able to:

See difference in structural levels and functional organisation of human genome

Identify mechanisms of regulating gene expression

Understand genetic experiments which lead to determining causes for genetic diseases.

Explain methodology of basic techniques of molecular genetics

To use the internet and other learning sources with great understanding
CONTENT OF THE SUBJECT:
Theoretical teaching – methodical units
1. Introduction to human genetics
2. nuclear acids
3. molecular organization of a cell
4. molecular organization of chromosome
5. laws of inheriting
6. deviation from Mendel rules of inheritance
7. functional organization of human genome
8. mutations, reparations and recombinations
9. molecular markers
10. prenatal diagnosis of genetic diseases
11. the ways of inheriting diseases
12. analysis of tests and signatures
Practical teaching – methodical units
1. NUCLEIC ACIDS- structure and function of DNA and RNA
2. CELL ORGANELLES-built and function and microphotographies
3. CHROMOSOMES OF A MAN, KARIOTYPE AND KARIOGRAM
4. CELL DIVISIONS AND GEMATOGENESIS
5. BASIC LAWS OF INHERITING
6. ANALYSIS OF FAMILY TREE
7. DEVIATION OF MENDEL RULES
8.CHARACTERISTICS RELATED TO SEX CHROMOZOMES X AND Y
9. MULTIPLE ALELS – ABO system of blood groups and Rh system
10. CHANGES IN NUMBER AND STRUCTURE OF CHROMOSOMES
11. POPULATION GENETICS
12. ISOLATION OF DNA AND ELECTROFORESIS
13. MOLECULAR MARKERS
14 . FORENSICS
Compulsory
RECOMMANDED
READING
Additional
1. Vapa Lj. Ćeliska i molekularna osnova nasledjivanja, , skripta, PMF Novi Sad , 2007.
2. Vapa Lj. Humana genetika, skripta, PMF Novi Sad , 2007.
3. Popić-Paljić F. Humana genetika-Medicinski fakultet, u štampi
1. Strachan T, Read AP. Human Molecular Genetics 3 Garland Publishing, UK, 2004.
2. Diklić V., Kosanović M., Nikoliš J., Dukić S., Biologija sa humanom genetikom, Grafopan,
Beograd, 2001.
Evaluation of students' work – No.of points per individual activity
Pre-exam obligations
Lectures
Exercises
Lectures
3
30
Seminar paper
The rest
Final exam
Written
Oral
67
-
Total
100
List of teachers and assistents
Associate
Assistent
3
1
1.
Lecturer
Prof.dr Feodora Popić-Paljić
Professor
PhD
2.
3.
4.
5.
Associate prof.
Professor
Scientist
1
Asst. Ivana Kavečan
Dr Miljen Maletin, Associate u nastavi
Nataša Jovanović, Associate u nastavi
Dr Iva Salatić, student na dokt.studijama
Chief of the department
Prof. dr Aleksndra Doronjski, ensuring