Tumor markers

2017-07-31T11:43:02+03:00[Europe/Moscow] en true Tumor marker, Ferritin, Gastrin, Human chorionic gonadotropin, D-lactate dehydrogenase, Sialic acid, Hyaluronic acid, Leucyl aminopeptidase, BRCA2, Thyroglobulin, Glucose-6-phosphate isomerase, Alpha-methylacyl-CoA racemase, Lactate dehydrogenase, Lipotropin, Normetanephrine flashcards Tumor markers
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  • Tumor marker
    A tumor marker is a biomarker found in blood, urine, or body tissues that can be elevated by the presence of one or more types of cancer.
  • Ferritin
    Ferritin is a universal intracellular protein that stores iron and releases it in a controlled fashion.
  • Gastrin
    Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility.
  • Human chorionic gonadotropin
    Human chorionic gonadotropin (hCG) is a hormone produced by the placenta after implantation.
  • D-lactate dehydrogenase
    D-lactate dehydrogenase (EC 1.1.1.28, lactic acid dehydrogenase, lactic acid dehydrogenase, D-specific lactic dehydrogenase, D-(-)-lactate dehydrogenase (NAD+), D-lactic acid dehydrogenase, D-lactic dehydrogenase) is an enzyme with systematic name (R)-lactate:NAD+ oxidoreductase.
  • Sialic acid
    Sialic acid is a generic term for the N- or O-substituted derivatives of neuraminic acid, a monosaccharide with a nine-carbon backbone.
  • Hyaluronic acid
    Hyaluronic acid (HA; conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues.
  • Leucyl aminopeptidase
    Leucyl aminopeptidases (EC 3.4.11.1, leucine aminopeptidase, LAPs, leucyl peptidase, peptidase S, cytosol aminopeptidase, cathepsin III, L-leucine aminopeptidase, leucinaminopeptidase, leucinamide aminopeptidase, FTBL proteins, proteinates FTBL, aminopeptidase II, aminopeptidase III, aminopeptidase I) are enzymes that preferentially catalyze the hydrolysis of leucine residues at the N-terminus of peptides and proteins.
  • BRCA2
    BRCA2 and BRCA2 (/ˌbrækəˈtuː/) are a human gene and its protein product, respectively.
  • Thyroglobulin
    (Not to be confused with Thyroxine-binding globulin, a carrier protein responsible for carrying the thyroid hormones in the blood.) Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by the follicular cells of the thyroid and used entirely within the thyroid gland.
  • Glucose-6-phosphate isomerase
    Glucose-6-phosphate isomerase (GPI), alternatively known as phosphoglucose isomerase (PGI) or phosphohexose isomerase (PHI), is an enzyme that in humans is encoded by the GPI gene on chromosome 19.
  • Alpha-methylacyl-CoA racemase
    In enzymology, an alpha-methylacyl-CoA racemase, also known as AMACR, is an enzyme that catalyzes the following chemical reaction: (2R)-2-methylacyl-CoA (2S)-2-methylacyl-CoA In mammalian cells, the enzyme is responsible for converting (2R)-methylacyl-CoA esters to their (2S)-methylacyl-CoA epimers and known substrates, including coenzyme A esters of pristanic acid (mostly derived from phytanic acid, a 3-methyl branched-chain fatty acid that is abundant in the diet) and bile acids derived from cholesterol.
  • Lactate dehydrogenase
    Lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells (animals, plants, and prokaryotes).
  • Lipotropin
    Lipotropin is a hormone produced by the cleavage of pro-opiomelanocortin (POMC).
  • Normetanephrine
    Normetanephrine is a metabolite of norepinephrine created by action of catechol-O-methyl transferase on norepinephrine.