Transmembrane proteins

2017-07-30T03:33:05+03:00[Europe/Moscow] en true Integrin, Cadherin, Syntaxin, Glycophorin, Coenzyme Q – cytochrome c reductase, Major intrinsic proteins, Chloride channel, Cation diffusion facilitator, Formate-nitrite transporter, Small-conductance mechanosensitive channel, Nucleobase cation symporter-2, Proton-pumping pyrophosphatase, Fumarate reductase, Light-harvesting complexes of green plants, Bacterial antenna complex, Photosystem II light-harvesting protein, Oligosaccharide-transporting ATPase, Photosynthetic reaction centre protein family, Cytochrome c oxidase subunit I, Phage major coat protein, Cytochrome C1, V-ATPase, M2 proton channel, Major facilitator superfamily, Organic anion-transporting polypeptide, Pilin, Ion channel family, ATP synthase subunit C, FXYD6, Cytochrome b, Polycystin cation channel family, Potassium transporter family, Ryanodine-Inositol 1,4,5-triphosphate receptor calcium channels, Transient receptor potential calcium channel family, P2X purinoreceptor, Protein-S-isoprenylcysteine O-methyltransferase, Lactose permease, Bcl-2 family, Innexin, Large-conductance mechanosensitive channel, Porin (protein), SecA, MT-ATP6, Bacterial rhodopsins, Disulfide bond formation protein B, Neurotransmitter sodium symporter, Potassium channel tetramerisation domain, SecY protein, Transmembrane domain of ABC transporters, Sulfatase, ATP synthase alpha/beta subunits, ATP synthase gamma subunit, Proton ATPase, Cytochrome c oxidase subunit II, Cytochrome c oxidase subunit III, APC Family, AGCS family, Calcium ATPase, Betaine transporter, Myelin proteolipid protein, Nucleobase cation symporter-1, Sodium-solute symporter, Calcium-dependent chloride channel, MACPF, Tryptophan-rich sensory protein, Translocase of the inner membrane, Dispanin, NhaA family, Nicotinamide ribonucleoside uptake transporters, P-Aminobenzoyl-glutamate transporter, Sodium-proton antiporter, F420H2DH family flashcards Transmembrane proteins
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  • Integrin
    Integrins are transmembrane receptors that are the bridges for cell-cell and cell-extracellular matrix (ECM) interactions.
  • Cadherin
    Cadherins (named for "calcium-dependent adhesion") are a class of type-1 transmembrane proteins.
  • Syntaxin
    Syntaxins are a family of membrane integrated Q-SNARE proteins participating in exocytosis.
  • Glycophorin
    A glycophorin is a sialoglycoprotein of the membrane of a red blood cell.
  • Coenzyme Q – cytochrome c reductase
    The coenzyme Q : cytochrome c — oxidoreductase, sometimes called the cytochrome bc1 complex, and at other times complex III, is the third complex in the electron transport chain (EC, playing a critical role in biochemical generation of ATP (oxidative phosphorylation).
  • Major intrinsic proteins
    Major intrinsic proteins comprise a large superfamily of transmembrane protein channels that are grouped together on the basis of homology.
  • Chloride channel
    Chloride channels are a superfamily of poorly understood ion channels specific for chloride.
  • Cation diffusion facilitator
    Cation diffusion facilitators (CDFs) are integral membrane proteins that increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt.
  • Formate-nitrite transporter
    The Formate-Nitrite Transporter (FNT) Family (TC# 1.A.16) is a family of homologous transmembrane proteins belonging to the Major Intrinsic Protein (MIP) Superfamily.
  • Small-conductance mechanosensitive channel
    Members of the Small Conductance Mechanosensitive Ion Channel (MscS) Family (TC# 1.A.23) provide protection against hypo-osmotic shock in bacteria, responding both to stretching of the cell membrane and to membrane depolarization.
  • Nucleobase cation symporter-2
    The Nucleobase:Cation Symporter-2 (NCS2) Family, also called the Nucleobase/Ascorbate Transporter (NAT) Family, consists of over 1000 sequenced proteins derived from gram-negative and gram-positive bacteria, archaea, fungi, plants and animals.
  • Proton-pumping pyrophosphatase
    Two types of inorganic diphosphatase, very different in terms of both amino acid sequence and structure, have been characterised to date: soluble and transmembrane proton-pumping pyrophosphatases (sPPases and H(+)-PPases, respectively).
  • Fumarate reductase
    Fumarate reductase is the enzyme that converts fumarate to succinate, and is important in microbial metabolism as a part of anaerobic respiration.
  • Light-harvesting complexes of green plants
    The light-harvesting complex (or antenna complex) is an array of protein and chlorophyll molecules embedded in the thylakoid membrane of plants, which transfer light energy to one chlorophyll a molecule at the reaction center of a photosystem.
  • Bacterial antenna complex
    Bacterial antenna complex proteins are the main light-absorbing components in photosynthetic bacteria.
  • Photosystem II light-harvesting protein
    Photosystem II light-harvesting proteins are the intrinsic transmembrane proteins CP43 (PsbC) and CP47 (PsbB) occurring in the reaction centre of photosystem II.
  • Oligosaccharide-transporting ATPase
    In enzymology, an oligosaccharide-transporting ATPase (EC is an enzyme that catalyzes the chemical reaction ATP + H2O + oligosaccharideout ADP + phosphate + oligosaccharidein The 3 substrates of this enzyme are ATP, H2O, and oligosaccharide, whereas its 3 products are ADP, phosphate, and oligosaccharide.
  • Photosynthetic reaction centre protein family
    Photosynthetic reaction centre proteins are main protein components of photosynthetic reaction centres of bacteria and plants.
  • Cytochrome c oxidase subunit I
    "Cox1" redirects here.
  • Phage major coat protein
    In molecular biology, a phage major coat protein is an alpha-helical protein that forms a viral envelope of filamentous bacteriophages.
  • Cytochrome C1
    Cytochrome C1 (also known as Complex III subunit 4) is a protein encoded by the CYC1 gene.
  • V-ATPase
    Vacuolar-type H+-ATPase (V-ATPase) is a highly conserved evolutionarily ancient enzyme with remarkably diverse functions in eukaryotic organisms.
  • M2 proton channel
    The Matrix-2 (M2) protein is a proton-selective ion channel protein, integral in the viral envelope of the influenza A virus.
  • Major facilitator superfamily
    The major facilitator superfamily (MFS) is a class of membrane transport proteins that facilitate movement of small solutes across cell membranes in response to chemiosmotic gradients.
  • Organic anion-transporting polypeptide
    An organic anion-transporting polypeptide (OATP) is a membrane transport protein or 'transporter' that mediates the transport of mainly organic anions across the cell membrane.
  • Pilin
    Pilin refers to a class of fibrous proteins that are found in pilus structures in bacteria.
  • Ion channel family
    Transmembrane cation channel superfamily was defined in InterPro and Pfam as the family of tetrameric ion channels.
  • ATP synthase subunit C
    ATPase, subunit C of F0/V0 complex is the main transmembrane subunit of V-type, A-type and F-type ATP synthases.
  • FXYD6
    FXYD6 (pronounced fix-id six), or FXYD domain-containing ion transport regulator 6, is a gene which is located at the 11q23.
  • Cytochrome b
    Cytochrome b is a protein found in the mitochondria of eukaryotic cells.
  • Polycystin cation channel family
    The Polycystin Cation Channel (PCC) Family (TC# 1.A.5) consists of several transporters ranging in size from 500 to over 4000 amino acyl residues (aas) in length and exhibiting between 5 and 18 transmembrane segments (TMSs).
  • Potassium transporter family
    The K+ Transporter (Trk) Family is a member of the voltage-gated ion channel (VIC) superfamily.
  • Ryanodine-Inositol 1,4,5-triphosphate receptor calcium channels
    The ryanodine-inositol 1,4,5-triphosphate receptor Ca2+ channel (RIR-CaC) family (TC# 1.A.3) consists of several receptor proteins exhibiting 4 to 6 transmembrane segments (TMSs), although ryanodine receptor Ca2+ release channel (RyR2; TC# 1.A.3.1.1), of Homo sapiens exhibits 10 TMSs.
  • Transient receptor potential calcium channel family
    The transient receptor potential Ca2+ channel (TRP-CC) family (TC# 1.A.4) is a member of the voltage-gated ion channel (VIC) superfamily and consists of cation channels conserved from worms to humans.
  • P2X purinoreceptor
    The ATP-gated P2X Receptor Cation Channel (P2X Receptor) Family (TC# 1.A.7) consists of cation-permeable ligand gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP).
  • Protein-S-isoprenylcysteine O-methyltransferase
    The isoprenylcysteine o-methyltransferase (EC carries out carboyxl methylation of cleaved eukaryotic proteins that terminate in a CaaX motif.
  • Lactose permease
    Lactose permease is a membrane protein which is a member of the major facilitator superfamily.
  • Bcl-2 family
    The Bcl-2 Family (TC# 1.A.21) consists of apoptosis regulator Bcl-2 and its homologues.
  • Innexin
    Innexins (TC# 1.A.25), or gap junction proteins, are structurally related transmembrane proteins that assemble to form invertebrate gap junctions.
  • Large-conductance mechanosensitive channel
    The Large Conductance Mechanosensitive Ion Channel (MscL) Family (TC# 1.A.22) consists of pore-forming membrane proteins that are responsible for translating physical forces applied to cell membranes into electrophysiological activities.
  • Porin (protein)
    Porins are beta barrel proteins that cross a cellular membrane and act as a pore through which molecules can diffuse.
  • SecA
    The SecA protein is a cell membrane associated subunit of the eubacterial Sec or Type II secretory pathway, a system which is responsible for the secretion of proteins through the cell membrane.
  • MT-ATP6
    MT-ATP6 (or ATP6) is a mitochondrial gene encoding the ATP synthase Fo subunit 6 (or subunit/chain A).
  • Bacterial rhodopsins
    Bacterial rhodopsins are a family of bacterial opsins.
  • Disulfide bond formation protein B
    Disulfide bond formation protein B (DsbB) is a protein component of the pathway that leads to disulfide bond formation in periplasmic proteins of Escherichia coli and other bacteria.
  • Neurotransmitter sodium symporter
    Members of the Neurotransmitter:Sodium Symporter (NSS) family (TC# 2.A.22) catalyze uptake of a variety of neurotransmitters, amino acids, osmolytes and related nitrogenous substances by a solute:Na+ symport mechanism.
  • Potassium channel tetramerisation domain
    K+ channel tetramerisation domain is the N-terminal, cytoplasmic tetramerisation domain (T1) of voltage-gated K+ channels.
  • SecY protein
    The SecY protein is the main transmembrane subunit of the eubacterial Sec or Type II secretory pathway and a protein-secreting ATPase complex, also known as a translocon.
  • Transmembrane domain of ABC transporters
    ABC transporter transmembrane domain is the main transmembrane structural unit of ATP-binding cassette transporter proteins, consisting of six alpha helix transmembrane domains which traverse the plasma membrane.
  • Sulfatase
    Sulfatases EC 3.1.
  • ATP synthase alpha/beta subunits
    Some ATPases work in reverse, using the energy from the hydrolysis of ATP to create a proton gradient.
  • ATP synthase gamma subunit
    Gamma subunit of ATP synthase F1 complex forms the central shaft that connects the F0 rotary motor to the F1 catalytic core.
  • Proton ATPase
    In the field of enzymology, the proton-ATPase (EC is an enzyme that catalyzes the following chemical reaction: ATP + H2O + H+in ADP + phosphate + H+out The 3 substrates of this enzyme are ATP, H2O, and H+, whereas its 3 products are ADP, phosphate, and H+.
  • Cytochrome c oxidase subunit II
    Cytochrome c oxidase subunit 2, also known as cytochrome c oxidase polypeptide II, is a protein that in humans is encoded by the MT-CO2 gene.
  • Cytochrome c oxidase subunit III
    Cytochrome c oxidase subunit 3 is an enzyme that in humans is encoded by the MT-CO3 gene.
  • APC Family
    The Amino Acid-Polyamine-Organocation (APC) Family (TC# 2.A.3) of transport proteins includes members that function as solute:cation symporters and solute:solute antiporters.
  • AGCS family
    Members of the Alanine or Glycine:Cation Symporter (AGCS) Family (TC# 2.A.25) transport alanine and/or glycine in symport with Na+ and or H+.
  • Calcium ATPase
    Ca2+ ATPase is a form of P-ATPase that transfers calcium after a muscle has contracted.
  • Betaine transporter
    Proteins of the Betaine/Carnitine/Choline Transporter (BCCT) family (TC# 2.A.15) are found in Gram-negative and Gram-positive bacteria and archaea.
  • Myelin proteolipid protein
    Myelin proteolipid protein (PLP or lipophilin) is the major myelin protein from the central nervous system (CNS).
  • Nucleobase cation symporter-1
    The Nucleobase:Cation Symporter-1 (NCS1) Family (TC# 2.A.39) consists of over 1000 currently sequenced proteins derived from Gram-negative and Gram-positive bacteria, archaea, fungi and plants.
  • Sodium-solute symporter
    Members of the Solute:Sodium Symporter (SSS) Family (TC# 2.A.21) catalyze solute:Na+ symport.
  • Calcium-dependent chloride channel
    The Calcium-Dependent Chloride Channel (Ca-ClC) Family (TC# 1.A.17) consists of eukaryotic proteins that are required for normal electrolyte and fluid secretion, olfactory perception, and neuronal and smooth muscle excitability in animals.
    The Membrane Attack Complex/Perforin (MACPF) superfamily, sometimes referred to as the MACPF/CDC superfamily, is named after a domain that is common to the membrane attack complex (MAC) proteins of the complement system (C6, C7, C8α, C8β and C9) and perforin (PF).
  • Tryptophan-rich sensory protein
    Tryptophan-rich sensory proteins (TspO) are a family of proteins that are involved in transmembrane signalling.
  • Translocase of the inner membrane
    The translocase of the inner membrane (TIM) is a complex of proteins found in the inner mitochondrial membrane of the mitochondria.
  • Dispanin
    In molecular biology, the protein family Dispanin is another name for Interferon-induced transmembrane protein (IFITM).
  • NhaA family
    Na+/H+ antiporter A (NhaA) family (TC# 2.A.33) contains a number of bacterial sodium-proton antiporter (SPAP) proteins.
  • Nicotinamide ribonucleoside uptake transporters
    The Nicotinamide Ribonucleoside (NR) Uptake Permease (PnuC) Family (TC# 4.B.1) is a family of transmembrane transporters that is part of the TOG superfamily.
  • P-Aminobenzoyl-glutamate transporter
    The p-aminobenzoyl-glutamate transporter (AbgT) family (TC# 2.A.68) is a family of transporter proteins belonging to the ion transporter (IT) superfamily.
  • Sodium-proton antiporter
    Sodium/proton antiporters are essential secondary-active transporters for sodium and pH homeostasis.
  • F420H2DH family
    The H+-translocating F420H2 Dehydrogenase (F420H2DH) Family (TC# 3.D.9) is a member of the Na+ transporting Mrp superfamily.