Hosam Mohamed-
broad spectrum gm + & gm-
What is the spectrum for Tetracyclines?
-
F; can be cidal at very high concentrations or very susceptible bacteria
Tetracyclines are always static. T/F?
-
neutral or alkaline
Tetracyclines are stable at pH > 2, but inactive at ___________ solutions.
-
dairy & antacids; causes chelation
What substances must be avoided when taking Tetracyclines? Why?
-
efflux, impaired influx, ribosome protection, teto
How do bacteria exhibit resistance to tetracyclines?
-
reversible retardation of bone growth, teeth discoloration in infants & young children
What are bone SE's associated with Tetracycline?
-
renal tubular acidosis, reversible faconi-like syndrome, reversible phototoxicity
What are kidney/skin SE's associated with Tetracycline?
-
out of date TC products
What causes Faconi-like syndrome?
-
d
Phototoxicity is increased in patients who take ______.
a) doxycycline
b) tetracycline
c) minocycline
d) demecyclocline
-
c
The risk of phototoxicity is rare in patients who take _______.
a) doxycycline
b) tetracycline
c) minocycline
d) demecyclocline
-
a,b
The risk of phototoxicity is lower in patients who take ______.
a) doxycycline
b) tetracycline
c) minocycline
d) demecyclocline
-
digoxin, methoxyflorane
What are drug interactions associated with Tetracyclines?
-
ehrlichiosis, helicobacter pylori, syphilis, cutibacterium acnes
Tetracyclines are 2nd line treatment for:
