broad spectrum gm + & gm-
What is the spectrum for Tetracyclines?
F; can be cidal at very high concentrations or very susceptible bacteria
Tetracyclines are always static. T/F?
neutral or alkaline
Tetracyclines are stable at pH > 2, but inactive at ___________ solutions.
dairy & antacids; causes chelation
What substances must be avoided when taking Tetracyclines? Why?
efflux, impaired influx, ribosome protection, teto
How do bacteria exhibit resistance to tetracyclines?
reversible retardation of bone growth, teeth discoloration in infants & young children
What are bone SE's associated with Tetracycline?
renal tubular acidosis, reversible faconi-like syndrome, reversible phototoxicity
What are kidney/skin SE's associated with Tetracycline?
out of date TC products
What causes Faconi-like syndrome?
d
Phototoxicity is increased in patients who take ______.
a) doxycycline
b) tetracycline
c) minocycline
d) demecyclocline
c
The risk of phototoxicity is rare in patients who take _______.
a) doxycycline
b) tetracycline
c) minocycline
d) demecyclocline
a,b
The risk of phototoxicity is lower in patients who take ______.
a) doxycycline
b) tetracycline
c) minocycline
d) demecyclocline
digoxin, methoxyflorane
What are drug interactions associated with Tetracyclines?
ehrlichiosis, helicobacter pylori, syphilis, cutibacterium acnes
Tetracyclines are 2nd line treatment for: